Skip to main content
Elsevier

Books in Life sciences

  • Monoclonal Antibodies

    Meeting the Challenges in Manufacturing, Formulation, Delivery and Stability of Final Drug Product
    • 1st Edition
    • Steven Shire
    • English
    Monoclonal antibodies (MAbs) are currently the major class of protein bio therapeutic being developed by biotechnology and pharmaceutical companies. Monoclonal Antibodies discusses the challenges and issues revolving around development of a monoclonal antibody produced by recombinant DNA technology into a therapeutic agent.This book covers downstream processing which includes design of processes to manufacture the formulation, formulation design, fill and finish into closure systems and routes of administration. The characterization of the final drug product is covered where the use of biophysical methods combined with genetic engineering is used to understand the solution properties of the formulation. The latter has become very important since many indications such as arthritis and asthma require the development of formulations for subcutaneous delivery (SC). The development of formulations for IV delivery is also important and comes with a different set of challenges. The challenges and strategies that can overcome these limitations are discussed in this book, starting with an introduction to these issues, followed by chapters detailing strategies to deal with them. Subsequent chapters explore the processing and storage of mAbs, development of delivery device technologies and conclude with a chapter on the future of mAbs in therapeutic remedies.

  • Regenerative Engineering of Musculoskeletal Tissues and Interfaces

    • 1st Edition
    • Syam Nukavarapu + 2 more
    • English
    Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces.

  • Modeling Food Processing Operations

    • 1st Edition
    • Serafim Bakalis + 2 more
    • English
    Computational modeling is an important tool for understanding and improving food processing and manufacturing. It is used for many different purposes, including process design and process optimization. However, modeling goes beyond the process and can include applications to understand and optimize food storage and the food supply chain, and to perform a life cycle analysis. Modeling Food Processing Operations provides a comprehensive overview of the various applications of modeling in conventional food processing. The needs of industry, current practices, and state-of-the-art technologies are examined, and case studies are provided. Part One provides an introduction to the topic, with a particular focus on modeling and simulation strategies in food processing operations. Part Two reviews the modeling of various food processes involving heating and cooling. These processes include: thermal inactivation; sterilization and pasteurization; drying; baking; frying; and chilled and frozen food processing, storage and display. Part Three examines the modeling of multiphase unit operations such as membrane separation, extrusion processes and food digestion, and reviews models used to optimize food distribution.

  • Grapevine Breeding Programs for the Wine Industry

    • 1st Edition
    • Andrew G. Reynolds
    • English
    Grapevine Breeding Programs for the Wine Industry: Traditional and Molecular Techniques summarizes recent trends in grapevine breeding, both in terms of research and practical programs. The first group of chapters covers the challenges faced by breeders and existing and emerging techniques used to combat them. Two further groups of chapters focus on grapevine breeding programs in different wine-producing countries around the world. With authoritative contributions from experts across the world’s winemaking regions, this book will be an essential reference for all those involved in viticulture and oeneology wanting to explore new methods, understand different approaches and refine existing practices.

  • Advances in Parasitology

    • 1st Edition
    • Volume 88
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies of parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. The 2013 impact factor is 4.36

  • Advances in Agronomy

    • 1st Edition
    • Volume 131
    • English
    Advances in Agronomy continues to be recognized as a leading reference and a first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. Five volumes are published yearly which ensures that authors’ contributions are disseminated to the readership in a timely manner. As always, the subjects covered are varied and exemplary of the myriad of subject matter dealt with by this long-running serial.

  • The Protective Arm of the Renin Angiotensin System (RAS)

    Functional Aspects and Therapeutic Implications
    • 1st Edition
    • Thomas Unger + 2 more
    • English
    The Protective Arm of the Renin Angiotensin System: Functional Aspects and Therapeutic Implications is the first comprehensive publication to signal the protective role of a distinct part of the renin–angiotensin system (RAS), providing readers with early insight into a complex system which will become of major medical importance in the near future. Focusing on recent research, The Protective Arm of the Renin Angiotensin System presents a host of new experimental studies on specific components of the RAS, namely angiotensin AT2 receptors (AT2R), the angiotensin (1–7) peptide with its receptor Mas, and the enzyme ACE 2, which exert significant beneficial, health-promoting actions by counterbalancing the well-known harmful arm of the RAS with its classical angiotensin AT1 receptor. This innovative concept of the protective arm of the RAS, examined in this reference, represents an indispensable background and will be a strong support for biomedical students, researchers, cardiologists, surgeons, nephrologists, diabetologists, and endocrinologists, as well as any other physician or researcher concerned with RAS physiology, pathophysiology and clinical implications.

  • Olive and Olive Oil Bioactive Constituents

    • 1st Edition
    • Dimitrios Boskou
    • English
    The market is flooded with products posing as elixirs, supplements, functional foods, and olive oil alternatives containing phenols obtained from multiple olive sources. This technically-oriented book will be of value to nutritionists and researchers in the biosciences. It unravels the body of science pertaining to olive minor constituents in relation to new chemical knowledge, technological innovations, and novel methods of recovery, parallel to toxicology, pharmacology, efficacy, doses, claims, and regulation. Topics include: the biological importance of bioactive compounds present in olive products; developments and innovations to preserve the level of bioactives in table olives and olive oil; and importance of variety, maturity, processing of olives, storage, debittering of olives and table olives as a valuable source of bioactive compounds.

  • Sunflower

    Chemistry, Production, Processing, and Utilization
    • 1st Edition
    • Enrique Martínez-Force + 2 more
    • English
    This comprehensive reference delivers key information on all aspects of sunflower. With over 20 chapters, this book provides an extensive review of the latest developments in sunflower genetics, breeding, processing, quality, and utilization; including food, energy and industrial bioproduct applications. World-renowned experts in this field review U.S. and international practices, production, and processing aspects of sunflower.

  • Nerves and Nerve Injuries

    Vol 2: Pain, Treatment, Injury, Disease and Future Directions
    • 1st Edition
    • R. Shane Tubbs + 5 more
    • English
    Nerves and Nerve Injuries is a must-have for clinicians and researchers dealing with the Peripheral Nervous System and neuropathy. An indispensable work for anyone studying the nerves or treating patients with nerve injuries, these books will become the ‘go to’ resource in the field. The nerves are treated in a systematic manner, discussing details such as their anatomy (both macro- and microscopic), physiology, examination (physical and imaging), pathology, and clinical and surgical interventions. The authors contributing their expertise are international experts on the subject. The books cover topics from detailed nerve anatomy and embryology to cutting-edge knowledge related to treatment, disease and mathematical modeling of the nerves. Nerves and Nerve Injuries Volume 2 focuses on pain, treatment, injury, disease and future directions in the field. This volume also addresses new information regarding neural interfaces, stem cells, medical and surgical treatments, and medical legal issues following nerve injury.

Related subjects