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    • Lipid Analysis

      • 1st Edition
      • June 5, 2014
      • William W. Christie
      • English
      • eBook
        9 7 8 1 4 8 3 1 8 7 1 7 4
      Lipid Analysis: Isolation, Separation, Identification, and Structural Analysis of Lipids focuses on the methods, principles, and approaches involved in the isolation, identification, separation, and structural analysis of lipids. The publication first elaborates on the structure, chemistry and occurrence of lipids, isolation of lipids from tissues, and chromatographic and spectroscopic analysis of lipids. Discussions focus on equipping a laboratory for lipid analysis, spectroscopy, chromatographic procedures, general principles of solvent extraction procedures, structural features of lipids important in analyses, simple and complex lipids, and fatty acids. The text then examines the preparation of volatile derivatives of lipids and analysis of fatty acids and simple lipid classes. Topics include alkyl diglycerides and neutral plasmalogens, analysis of the hydrolysis products of simple lipids, preparation of large quantities of pure fatty acids, physical characterization of fatty acids, location of double bonds in fatty acid chains, and saponification of lipids. The manuscript covers the analysis and radioassay of isotopically-labelle... lipids, enzymatic hydrolysis of lipids, and analysis of molecular species of lipids. The publication is a primary reference for researchers interested in lipid analysis.

    • A Text-Book of Bacteriology

      • 9th Edition
      • June 5, 2014
      • R. W. Fairbrother + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 9 5 5 7 5
      Fairbrother's Textbook of Bacteriology, Tenth Edition provides an outline of the medical aspects of bacteriology. This book emphasizes the biological relationship of allied organisms. This edition begins with an overview of the various elements of the bacterial cell in detail, starting with external features such as flagella and capsules, and working inwards to the cytoplasm. This text then describes the principal toxic effects of the different groups of anti-bacterial substances. Other chapters consider the relationship of the different types of hypersensitivity to classical immune responses. This book discusses as well the earliest application of a specific chemical substance to the treatment of microbial disease. This book is a valuable resource for medical students. Bacteriologists, chemists, pathologists, and microbiologists will also find this book useful.

    • Enzymes

      • 2nd Edition
      • June 5, 2014
      • Malcolm Dixon + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 2 5 6 0 9
      Enzymes, Second Edition provides information pertinent to the developments in the field of enzymology. This book presents the properties of enzymes as chemical catalysts or simply as chemical substances. Organized into 13 chapters, this edition begins with an overview of the range of action or specificity of enzymes. This text then discusses the special techniques employed in the isolation of enzymes and explores the considerable progress in the study of the properties and functions of enzymes. Other chapters consider the mechanism of enzyme catalysis by more direct methods, including the use of isotopes. This book discusses as well the mechanism of the biosynthesis of enzymes and the means by which their chemical structure is determined by the genetic material of the chromosomes. The final chapter deals with the essential aspects of the enzymatic system linking energy-producing processes with energy-utilizing processes. This book is a valuable resource for biochemists, physical chemists, and research workers.

    • The Role of Chromosomes in Development

      • 1st Edition
      • June 5, 2014
      • Michael Locke
      • English
      • Paperback
        9 7 8 1 4 8 3 2 5 4 2 1 0
      • eBook
        9 7 8 1 4 8 3 2 6 3 6 5 6
      The Role of Chromosomes in Development is a collection of papers that deals with structural patterns and functional organization of chromosomes. Some papers discuss chromosomal proteins, DNA replication sequences in higher animals, and the implications of localized DNA synthesis in polytene chromosomes. Several papers describe chromosomal RNA, nuclear RNA fractions, genetic control, and the regulation of developmental pathways. One paper concerns the "bithorax" series that controls the development of certain body segments of the fly in a polarized and coordinated manner reminiscent of the genes in the operons of microorganisms. The bithorax genes evidently exploit and amplify a gradient arising from an anteroposterior gradient during mitotic division rates. The bithorax genes produces a whole set of new substances that repress certain systems of cellular differentiation, letting other systems to emerge and develop. Another paper investigates the hypothesis of diploid subnuclei as the architectural subunit of the ciliate macronucleus, as well as the hypothesis of "allelic repression" as the basis for certain examples of subnuclear differentiation. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology.

    • Lymphokines

      • 1st Edition
      • June 5, 2014
      • Edgar Pick
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 2 1 5 6
      • eBook
        9 7 8 1 4 8 3 2 6 6 9 9 2
      Lymphokines: A Forum for Immunoregulatory Cell Products deals with immunoregulatory cell products that produce lymphokines. Topics covered include the purification and characterization of transfer factor; activation of cytotoxicity and/or suppressor activity in murine macrophages by lymphokines, lipopolysaccharide, and polyinosinic-polycyt... acid; and the role of clotting processes in the action of lymphokines on macrophages. A comparison of the immune-modulating effects of interferon and interferon inducers is also presented. Comprised of 13 chapters, this volume begins with a discussion on transfer factor and its ability to react specifically with antigens. The clinical uses of transfer factor are considered with special emphasis on its value as a prophylactic agent. The reader is then introduced to the subject of T cell regulation of the immunoglobulin E (IgE) response via potentiating and suppressor lymphokines, together with the possible clinical application of IgE suppressive factors in the treatment of atopic diseases. Subsequent chapters examine the evidence in favor of the existence of T cell-derived polyclonal B cell activator (PBA) playing a role in both normal antibody responses and autoimmune diseases; the role of suppressor T cells and the associated lymphokines in contact sensitivity in mice; and lymphokine action on macrophages. The book also analyzes the genetics of the response of human and mouse cells to interferons. This monograph will be helpful to practitioners and researchers in the fields of microbiology and immunology.

    • Celiac Disease and Gluten

      • 1st Edition
      • June 5, 2014
      • Peter Koehler + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 2 2 0 7
      • Paperback
        9 7 8 0 1 2 8 1 0 1 3 4 6
      • eBook
        9 7 8 0 1 2 7 9 9 9 2 6 5
      Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities is a unique reference work—the first to integrate the insights of the causes and effects of celiac disease from the chemistry of reaction-causing foods to the diagnosis, pathogenesis, and symptoms that lead to proper diagnoses and treatment. With an estimated three million people in the United States alone affected by celiac disease, an autoimmune digestive disease, only five percent are properly diagnosed. Drawing on the connection between foods containing gluten and the resulting symptoms, this resource offers distinctive information that directly explores and links food science, medical diagnostics, and treatment information. A helpful tool for researchers and medical practitioners alike, Celiac Disease and Gluten: Multidisciplinary Challenges and Opportunities helps refine research targets, and provides a comprehensive overview on the multidisciplinary approaches to all crucial aspects related to celiac disease.

    • Mouse Models of the Nuclear Envelopathies and Related Diseases

      • 1st Edition
      • Volume 109
      • June 2, 2014
      • English
      • Hardback
        9 7 8 0 1 2 3 9 7 9 2 0 9
      • eBook
        9 7 8 0 1 2 3 9 8 4 6 4 7
      Volume 109 of Current Topics in Developmental Biology covers mouse models of the nuclear envelopathies and related diseases, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as mouse models neurodegenerative diseases including Parkinson’s and dystonia, muscle ageing and sarcopenia, cardiac failure and repair, ageing and prospects lifespan extension, lipodystrophy and the significance in fat regulation, also identifying developmental mutations in mammals and nuclear envelope and LINC complex in disease.

    • Tissue Engineering Using Ceramics and Polymers

      • 2nd Edition
      • June 2, 2014
      • Aldo R. Boccaccini + 1 more
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 3 9 8 4
      • Paperback
        9 7 8 0 8 5 7 0 9 7 1 2 5
      • eBook
        9 7 8 0 8 5 7 0 9 7 1 6 3
      The second edition of Tissue Engineering Using Ceramics and Polymers comprehensively reviews the latest advances in this area rapidly evolving area of biomaterials science. Part one considers the biomaterials used for tissue engineering. It introduces the properties and processing of bioactive ceramics and glasses, as well as polymeric biomaterials, particularly biodegradable polymer phase nanocomposites. Part two reviews the advances in techniques for processing, characterization, and modeling of materials. The topics covered range from nanoscale design in biomineralization strategies for bone tissue engineering to microscopy techniques for characterizing cells to materials for perfusion bioreactors. Further, carrier systems and biosensors in biomedical applications are considered. Finally, part three looks at the specific types of tissue and organ regeneration, with chapters concerning kidney, bladder, peripheral nerve, small intestine, skeletal muscle, cartilage, liver, and myocardial tissue engineering. Important developments in collagen-based tubular constructs, bioceramic nanoparticles, and multifunctional scaffolds for tissue engineering and drug delivery are also explained. Tissue Engineering Using Ceramics and Polymers is a valuable reference tool for both academic researchers and scientists involved in biomaterials or tissue engineering, including the areas of bone and soft-tissue reconstruction and repair, and organ regeneration.

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