Skip to main content
Elsevier
View Cart

Books in Life sciences

BooksJournals

    • Molecular Mechanisms of Immunological Self-Recognition

      • 1st Edition
      • June 28, 2014
      • Frederick Alt + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 2 5 0 1
      • eBook
        9 7 8 1 4 8 3 2 1 5 9 3 8
      Molecular Mechanisms of Immunological Self-Recognition covers the understanding of immunological self-recognition. The introductory chapter of the book summarizes the dawn of the insight into immunological tolerance, and provides an overview of research on the underlying mechanisms. The book addresses the developments in the molecular mechanisms of B and T cell tolerance and describes the failure of tolerance in autoimmunity. The text concludes by furnishing orienting perspectives and highlighting new information presented. The novel findings characterized as impressive advances pertain to the areas of B cell development and the generation of molecular diversity; V gene usage, especially from transgenes, in positive and negative thymic selection; the handling of positive and negative signals by T and B cells; anergy in postthymic T cells; the design of peptide-based therapy for autoimmune diseases; and the design of therapy with the aid of monoclonal antibodies. Immunologists will find the text useful.

    • Preservation and Shelf Life Extension

      • 1st Edition
      • March 21, 2014
      • Tatiana Koutchma
      • English
      • Paperback
        9 7 8 0 1 2 4 1 6 6 2 1 9
      • eBook
        9 7 8 0 1 2 4 1 6 6 6 8 4
      Preservation and Shelf Life Extension focuses on the basic principles of ultraviolet light technology as applied in low-UV transmittance treatments of food fluids and solid foods. It describes the features of UV light absorption in food fluids and available commercial systems, and provides case studies for UV treatment of fresh juices, dairy products, wines, and beer. The book also includes information on various continuous and pulsed UV sources and processing systems, as well as examples of specific treatments for fruits, vegetables, meat and poultry products.

    • Disorders of Mineral Metabolism

      • 1st Edition
      • May 10, 2014
      • Felix Bronner + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 6 6 6 7
      • eBook
        9 7 8 1 4 8 3 2 6 5 8 7 2
      Disorders of Mineral Metabolism, Volume I: Trace Minerals covers the pathophysiology of clinically relevant minerals and elements. This volume focuses on minerals whose average daily intake is under 50 mg. This text is composed of 12 chapters that tackle the clinical relevance and essentiality of various trace minerals in the human body, with particular emphasis on the disorders due to their abnormal metabolism. The trace mineral and elements considered in this volume include iron, coppers, zinc, lead, nickel, manganese, chromium, molybdenum, cadmium, aluminum, tin, lithium, and fluoride. Each chapter discusses the properties, body requirements, analysis, nutritional interactions, and toxicity of the mineral. This book will prove useful to biochemists, pathophysiologists, and workers in the medical field.

    • Bone Substitute Biomaterials

      • 1st Edition
      • July 21, 2014
      • K. Mallick
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 4 9 7 1
      • Paperback
        9 7 8 0 0 8 1 0 1 5 2 8 5
      • eBook
        9 7 8 0 8 5 7 0 9 9 0 3 7
      Bone substitute biomaterials are fundamental to the biomedical sector, and have recently benefitted from extensive research and technological advances aimed at minimizing failure rates and reducing the need for further surgery. This book reviews these developments, with a particular focus on the desirable properties for bone substitute materials and their potential to encourage bone repair and regeneration. Part I covers the principles of bone substitute biomaterials for medical applications. One chapter reviews the quantification of bone mechanics at the whole-bone, micro-scale, and non-scale levels, while others discuss biomineralization, osteoductivization, materials to fill bone defects, and bioresorbable materials. Part II focuses on biomaterials as scaffolds and implants, including multi-functional scaffolds, bioceramics, and titanium-based foams. Finally, Part III reviews further materials with the potential to encourage bone repair and regeneration, including cartilage grafts, chitosan, inorganic polymer composites, and marine organisms.

    • Viral Immunology and Immunopathology

      • 1st Edition
      • June 28, 2014
      • Abner Louis Notkins
      • English
      • eBook
        9 7 8 1 4 8 3 2 1 8 9 7 7
      Viral Immunology and Immunopathalogy covers topics concerning the role of cellular and humoral immunity in viral infections, factors responsible for the persistence and recurrence of viral infections in the presence of immunity, mechanisms of viral immunopathology, and concepts in the development of vaccines. The book describes the history of viral immunology; the synthesis and properties of viral antigens; and the humoral immune response to viruses. The text also discusses the mechanisms of viral neutralization; cellular immunity; the role of inflammatory cells and effector molecules in combating viral infections; and the genetic control of resistance. The book concludes with chapters on herd immunity; viral immunopathology; and viral immunology and immunopathology. Immunologists, pathologists, virologists, and microbiologists will find the book useful.

    • Introduction to Biostatistics

      • 1st Edition
      • May 19, 2014
      • Ronald N. Forthofer + 1 more
      • English
      • Paperback
        9 7 8 1 4 9 3 3 0 7 3 3 3
      • eBook
        9 7 8 1 4 8 3 2 9 6 7 4 6
      The Biostatistics course is often found in the schools of public Health, medical schools, and, occasionally, in statistics and biology departments. The population of students in these courses is a diverse one, with varying preparedness. The book assumes the reader has at least two years of high school algebra, but no previous exposure to statistics is required.Written for individuals who might be fearful of mathematics, this book minimizes the technical difficulties and emphasizes the importance of statistics in scientific investigation. An understanding of underlying design and analysis is stressed. The limitations of the research, design and analytical techniques are discussed, allowing the reader to accurately interpret results. Real data, both processed and raw, are used extensively in examples and exercises. Statistical computing packages - MINITAB, SAS and Stata - are integrated. The use of the computer and software allows a sharper focus on the concepts, letting the computer do the necessary number-crunching.

    • Switchable and Responsive Surfaces and Materials for Biomedical Applications

      • 1st Edition
      • December 11, 2014
      • Johnathan Zhang
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 7 1 3 2
      • eBook
        9 7 8 0 8 5 7 0 9 7 1 7 0
      Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering, drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors.

    • An Introduction to Medical Laboratory Technology

      • 1st Edition
      • May 12, 2014
      • F. J. Baker + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 9 6 0 5
      • eBook
        9 7 8 1 4 8 3 1 9 5 4 1 4
      An Introduction to Medical Laboratory Technology, Second Edition provides information pertinent to medical laboratory technology. This book discusses the importance of laboratory technology in hospital practice. Organized into seven sections encompassing 33 chapters, this edition begins with an overview of the role of the medical technologist in the diagnosis of disease by the use of certain accepted laboratory methods. This text then explains the general types of glassware that is widely used in medical laboratories. Other chapters consider the main methods of estimating the sugar content of body fluids, methods in feces and gastric analysis, and microscopical and chemical examination of urine. This book discusses as well the microscopic examination of bacteria, which necessitates making smears and hanging-drop preparations on microscope slides. The final chapter deals with some aspects of elementary physiology. This book is a valuable resource for students and junior technicians, as well as for qualified technologists and medical students.

    • Frontiers in Catecholamine Research

      • 1st Edition
      • May 18, 2014
      • Earl Usdin + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 5 5 8 6 9
      Frontiers in Catecholamine Research is a collection of papers presented at the Third International Catecholamine Symposium, held at the University of Strasbourg, Strasbourg, France, on May 20-25, 1973. This book is organized into nine parts encompassing 205 chapters. The text begins with a discussion on clinically and experimentally used drugs that have been developed or whose mechanism of action has been clarified through monoamine research. Parts II and III deal with enzymes related to catecholamine studies, their properties, regulation, genetics, mechanism of action, and localization. Parts IV and V examine the concepts of synaptic dynamics of brain regulators and the isolation, characterization, methods of analysis, and mechanism of action of catecholamines. Part VI focuses on the complexities that surround the extrapolation of catecholamine function into the realms of electrophysiology and behavior. Part VII discusses the metabolism, behavioral, neurological, and physiological effects of amphetamine and other drugs of abuse. The concluding parts describe the role of catecholamine and its metabolism in neurologic diseases, such as schizophrenia.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology