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Books in Life sciences

  • Twentieth Century Mouse Genetics

    A Historical and Scientific Review
    • 1st Edition
    • Robert P. Erickson
    • English
    Twentieth Century Mouse Genetics: A Historical and Scientific Review provides a comprehensive examination of key advances in mouse genetics throughout the 20th century. Here Dr. Robert P. Erickson, a leader in the field, identifies the contributions of historic mouse genetics studies, and how those approaches and early discoveries are still shaping human genetics research and medical genetics today. In addition to historical overviews, the author provides researcher biographies and updates connecting historic research to ongoing advances. Past studies discussed use the T/t complex as an example and include the origins of mouse genetics, the synthesis of genetics and evolution, cytogenetics and gene mapping, population genetics and mutation research, immunogenetics, reproductive genetics, molecular cloning, X-inactivation and epigenetics, sex determination, and pharmacogenetics. Here researchers, students, and clinicians will find fresh inspiration to engage in human genetics research employing mouse models and to translate those findings to clinical practice.
  • Epigenetics and Metabolomics

    • 1st Edition
    • Volume 28
    • Paban K. Agrawala + 1 more
    • English
    Epigenetics and Metabolomics, a new volume in the Translational Epigenetics series, offers a synthesized discussion of epigenetic control of metabolic activity, and systems-based approaches for better understanding these mechanisms. Over a dozen chapter authors provide an overview of epigenetics in translational medicine and metabolomics techniques, followed by analyses of epigenetic and metabolomic linkage mechanisms likely to result in effective identification of disease biomarkers, as well as new therapies targeting the removal of the inappropriate epigenetic alterations. Epigenetic interventions in cancer, brain damage, and neuroendocrine disease, among other disorders, are discussed in-depth, with an emphasis on exploring next steps for clinical translation and personalized healthcare.
  • Engineering Technologies and Clinical Translation

    Volume 3 of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy
    • 1st Edition
    • Mansoor M. Amiji + 1 more
    • English
    Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies, focusing specifically on the development of solutions for drug delivery and its clinical outcomes. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discus... biomaterial, microfluidic, and biodegradable devices, engineered microbes, personalized medicine, clinical approval process, and many other IO technologies. Engineering Technologies and Clinical Translation: Volume 3: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.
  • Valorization of Agri-Food Wastes and By-Products

    Recent Trends, Innovations and Sustainability Challenges
    • 1st Edition
    • Rajeev Bhat
    • English
    Valorization of Agri-Food Wastes and By-Products: Recent Trends, Innovations and Sustainability Challenges addresses the waste and by-product valorization of fruits and vegetables, beverages, nuts and seeds, dairy and seafood. The book focuses its coverage on bioactive recovery, health benefits, biofuel production and environment issues, as well as recent technological developments surrounding state of the art of food waste management and innovation. The book also presents tools for value chain analysis and explores future sustainability challenges. In addition, the book offers theoretical and experimental information used to investigate different aspects of the valorization of agri-food wastes and by-products. Valorization of Agri-Food Wastes and By-Products: Recent Trends, Innovations and Sustainability Challenges will be a great resource for food researchers, including those working in food loss or waste, agricultural processing, and engineering, food scientists, technologists, agricultural engineers, and students and professionals working on sustainable food production and effective management of food loss, wastes and by-products.
  • Pandemic Outbreaks in the 21st Century

    Epidemiology, Pathogenesis, Prevention, and Treatment
    • 1st Edition
    • Viswanath Buddolla
    • English
    In the past two decades, several pandemics have ravaged the globe, giving us several lessons on infectious disease epidemiology, the importance of initial detection and characterization of outbreak viruses, the importance of viral epidemic prevention steps, and the importance of modern vaccines. Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment summarizes the improvements in the 21st century to overcome / prevent / treat global pandemic with future prospective. Divided into 9 chapters, the book begins with an in-depth introduction to the lessons learned from the first pandemic of the 21st century. It describes the history, present and future in terms of detection, prevention and treatment. Followed by chapters on the outbreak, treatment strategies and clinical management of several infectious diseases like MERS, SARD and COVID 19, Pandemic Outbreaks in the Twenty-First Century: Epidemiology, Pathogenesis, Prevention, and Treatment, presents chapters on immunotherapies and vaccine technologies to combat pandemic outbreak and challenges. The book finishes with a chapter on the current knowledge and technology to control pandemic outbreaks. All are presented in a practical short format, making this volume a valuable resource for very broad academic audience.
  • Abiotic Stress and Legumes

    Tolerance and Management
    • 1st Edition
    • Vijay Pratap Singh + 5 more
    • English
    Abiotic Stress and Legumes: Tolerance and Management is the first book to focus on the ability of legume plants to adapt effectively to environmental challenges. Using the -omic approach, this book takes a targeted approach to understanding the methods and means of ensuring survival and maximizing the productivity of the legume plant by improving tolerance to environmental /abiotic stress factors including drought, temperature change, and other challenges.The book presents a comprehensive overview of the progress that has been made in identifying means of managing abiotic stress effects, specifically in legumes, including the development of several varieties which exhibit tolerance through high yield using transcriptomic, proteomic, metabolomic and ionomic approaches. Further, exogenous application of various stimulants such as plant hormones, nutrients, sugars, and polyamines has emerged as an alternative strategy to improve productivity under these environmental challenges.Abiotic Stress and Legumes: Tolerance and Management examines these emerging strategies and serves as an important resource for researchers, academicians and scientists, enhancing their knowledge and aiding further research.
  • Epigenetics in Psychiatry

    • 2nd Edition
    • Jacob Peedicayil + 2 more
    • English
    Epigenetics in Psychiatry, Second Edition covers all major areas of psychiatry in which extensive epigenetic research has been performed, fully encompassing a diverse and maturing field, including drug addiction, bipolar disorder, epidemiology, cognitive disorders, and the uses of putative epigenetic-based psychotropic drugs. Uniquely, each chapter correlates epigenetics with relevant advances across genomics, transcriptomics, and proteomics. The book acts as a catalyst for further research in this growing area of psychiatry. This new edition has been fully revised to address recent advances in epigenetic understanding of psychiatric disorders, evoking data consortia (e.g., CommonMind, ATAC-seq), single cell analysis, and epigenome-wide association studies to empower new research. The book also examines epigenetic effects of the microbiome on psychiatric disorders, and the use of neuroimaging in studying the role of epigenetic mechanisms of gene expression. Ongoing advances in epigenetic therapy are explored in-depth.
  • Field Crop Arthropod Pests of Economic Importance

    • 1st Edition
    • Peter A. Edde
    • English
    Field Crop Arthropod Pests of Economic Importance presents detailed descriptions of the biology and ecology of important arthropod pest of selected global field crops. Standard management options for insect pest control on crops include biological, non-chemical, and chemical approaches. However, because agricultural crops face a wide range of insect pests throughout the year, it can prove difficult to find a simple solution to insect pest control in many, if not most, cropping systems. A whole-farm or integrated pest management approach combines cultural, natural, and chemical controls to maintain insect pest populations below levels that cause economic damage to the crop. This practice requires accurate species identification and thorough knowledge of the biology and ecology of the target organism. Integration and effective use of various control components is often enhanced when the target organism is correctly identified, and its biology and ecology are known. This book provides a key resource toward that identification and understanding. Students and professionals in agronomy, insect detection and survey, and economic entomology will find the book a valuable learning aid and resource tool.
  • Systemic Drug Delivery Strategies

    Volume 2 of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy
    • 1st Edition
    • Mansoor M. Amiji + 1 more
    • English
    Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 examines the challenges of delivering immuno-oncology therapies, focusing specifically on the multiple technologies of affective drug delivery strategies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discusses methods of targeting tumors, CRISPR technology, and vaccine delivery among many other delivery strategies. Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.
  • Advancements and Technologies in Pig and Poultry Bacterial Disease Control

    • 1st Edition
    • Neil Foster + 2 more
    • English
    Advancements and Technologies in Pig and Poultry Bacterial Disease Control provides the most up-to-date knowledge on the tools and technologies used in the economics, prevention, monitoring and control of the most important bacterial diseases in these two important livestock species. Written by international experts in veterinary medicine, veterinary science, agricultural economics and environmental monitoring, this book provides state-of-the-art information regarding the application of technology to the prevention and control of bacterial disease in pigs and poultry. It presents the most up-to-date information on the major bacterial pathogens, why they are important, their epidemiology, pathogenesis and molecular basis of their virulence. Additional sections examine how genomic sequencing addresses the development of disease biomarkers for faster and highly specific diagnosis and how next generation sequencing can identify good and bad microflora. This book will be a valuable resource for veterinarians, epidemiologists, animal scientists, technologists, and researchers studying precision livestock farming. Students in veterinary, animal science and bio-science courses will also find it useful for its coverage of diseases and monitoring tools.
  • Hormones, Regulators and Viruses

    • 1st Edition
    • Volume 117
    • Gerald Litwack
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors
  • Microbes in Land Use Change Management

    • 1st Edition
    • Jay Shankar Singh + 3 more
    • English
    Microbes in Land Use Change Management details the various roles of microbial resources in management of land uses and how the microbes can be used for the source of income due to their cultivation for the purpose of biomass and bioenergy production. Using various techniques, the disturbed and marginal lands may also be restored eco-friendly in present era to fulfil the feeding needs of mankind around the globe. Microbes in Land Use Change Management provides standard and up to date information towards the land use change management using various microbial technologies to enhance the productivity of agriculture. Needless to say that Microbes in Land Use Change Management also considers the areas including generation of alternative energy sources, restoration of degraded and marginal lands, mitigation of global warming gases and next generation -omics technique etc. Land use change affects environment conditions and soil microbial community. Microbial population and its species diversity have influence in maintaining ecosystem balance. The study of changes of microbial population provides an idea about the variation occurring in a specific area and possibilities of restoration. Meant for a multidisciplinary audience Microbes in Land Use Change Management shows the need of next-generation omics technologies to explore microbial diversity.
  • Emerging Horizons in Neuromodulation: New Frontiers in Brain and Spine Stimulation

    • 1st Edition
    • Volume 159
    • English
    International Review of Neurobiology serial highlights new advances in the field with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Oncological Functional Nutrition

    Phytochemicals and Medicinal Plants
    • 1st Edition
    • Maira Rubi Segura Campos + 1 more
    • English
    Oncological Functional Nutrition: Phytochemicals and Medicinal Plants presents the anticancer activities, metabolism, mechanism of action, doses, and sources of various phytochemicals and medicinal plants. Broken into five parts, this book addresses cancer epidemiology, molecular and therapeutic bases of cancer, macro and micronutrients in cancer prevention and treatment, phytochemicals in the cancer treatment, and medical plants as potential functional foods or resources for the obtention of metabolites with anticancer activity. Written for nutritionists, food scientists, health professionals, oncologists, endocrinologists, natural product chemists, ethnobotanists, chemists, pharmacists, biochemists, and students studying relating fields, Oncological Functional Nutrition: Phytochemicals and Medicinal Plants will be a useful reference for those interested in learning more about functional nutrition and cancer.
  • Microbial Extremozymes

    Novel Sources and Industrial Applications
    • 1st Edition
    • Mohammed Kuddus
    • English
    Microbial Extremozymes: Novel Sources and Industrial Applications is a unique resource of practical research information on the latest novel sources and technologies regarding extremozymes in bioremediation, waste management, valorization of industrial by-products, biotransformation of natural polymers, nutrition, food safety and diagnosis of disease. The book's broad knowledge and varying applications are useful to the food industry, dairy industry, fruit and vegetable processing, and baking and beverages industries, as well as the pharmaceutical and biomedical industries. This is a concise, all-encompassing resource for a range of scientists needing knowledge of extremozymes to enhance and research. Furthermore, it provides an updated knowledge of microbial enzymes isolated from extreme environments (temperatures, etc.) and their biotechnological applications. It will be useful to researchers, scientists and students in enzyme research. In addition, users from the dairy and baking industries will benefit from the presented content.
  • Biochemistry of Lipids, Lipoproteins and Membranes

    • 7th Edition
    • Neale Ridgway + 1 more
    • English
    Biochemistry of Lipids, Lipoproteins and Membranes, Seventh Edition serves as a comprehensive, general reference book for scientists and students studying lipids, lipoproteins and membranes. Here, across 19 chapters, leaders in the field summarize fundamental concepts, recent research developments, data analysis, and implications for human disease and intervention. Topics discussed include lipid biology in both prokaryotes and eukaryotes, fatty acid synthesis, desaturation and elongation, and pathways leading to synthesis of complex phospholipids, sphingolipids and their structural variants. Chapters also examine how bioactive lipids are involved in cell signaling, with an emphasis on disease implications and pathological consequences. As the field advances, each chapter in this new edition has been fully revised to address emerging topics, with all-new coverage of lipid droplets and their role as regulatory organelles for energy homeostasis, as well as their relationship to obesity, liver disease and diabetes. Evolving research in fatty acid handling and storage in eukaryotes is also discussed in-depth, with new sections addressing fatty acid uptake, activation and lipolysis.
  • Twin and Family Studies of Epigenetics

    • 1st Edition
    • Volume 27
    • Shuai Li + 1 more
    • English
    Twin and Family Studies of Epigenetics, Volume 27, the latest release in the Translational Epigenetics series, gathers expert opinions on epigenetic twin and family study research methods, recent findings across various disease areas, and future directions. The book provides in-depth coverage of epigenetics fundamentals, twin and family epigenetic study design, and the broader role of epigenetics in answering questions on the developmental origins of health and disease. Throughout the volume, twin and family studies are employed to examine causes of epigenetic variation, the relationship between epigenetic modifications and mental illness, cancers, cardiovascular disease, diabetes, obesity, high blood pressure, and more. Emerging research methods applied in twin and family studies discussed include imaging epigenetics, exposure-specific DNA methylation changes, and unravelling time trends in epigenetic effects.
  • Scientific Principles of Adipose Stem Cells

    • 1st Edition
    • Lauren Kokai + 2 more
    • English
    Scientific Principles of Adipose Stem Cells provides readers with in-depth and expert knowledge on adipose stem cells, their developmental biologic origins, foundational research on ASC signaling mechanisms and immunomodulatory properties, and clinical insights into applications in regenerative medicine. Topics covered include basic adipose stem cell developmental biology and mechanisms of regulating self-renewal and activation in the stem cell niche, important methods for isolation and characterizing ASCs, and data on the impact on human demographics (age, sex, BMI) on ASC phenotype. A section devoted to ASC biology, ASCs for stem cell therapy and regenerative medicine, and ASCs in tissue engineering applications are also included. The book is written for scientists and clinicians who are broadly familiar with stem cells and basic cell biology principles and those seeking advanced information on adipose stem cells.
  • Cancer Immunology and Immunotherapy

    Volume 1 of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy
    • 1st Edition
    • Mansoor M. Amiji + 1 more
    • English
    Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.
  • Pathogenesis, Treatment and Prevention of Leishmaniasis

    • 1st Edition
    • Mukesh Samant + 1 more
    • English
    Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis.
  • Pandemic of Diabetes and Prediabetes: Prevention and Control, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 50-3
    • K M Venkat Narayan
    • English
    Provides in-depth, clinical reviews on diabetes and prediabetes prevention and control, providing actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field; Authors synthesize and distill the latest research and practice guidelines to create these timely topic-based reviews.
  • Fundamentals of Pediatric Imaging

    • 3rd Edition
    • Lane F. Donnelly
    • English
    Fundamentals of Pediatric Imaging, Third Edition presents the foremost techniques of pediatric medical image analysis and processing. It includes advanced imaging techniques, neuro applications, and highlights basic anatomy needed to understand this complex specialty. The book introduces the theory and concepts of pediatric digital image analysis and newly revised information on quality and safety topics, imaging modalities, imaging applications, and new discoveries in diseases and treatments. The newly revised edition provides updates in areas of expertise including neurologic, musculoskeletal, cardiac, chest, and GU imaging. Edited by Lane F. Donnelly, MD, recipient of the Society of Pediatric Radiology’s 2009 Singleton-Taybi Award, this book is sure to be a prime reference in pediatric medical imagining.
  • Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

    • 1st Edition
    • Xinyu Liu + 1 more
    • English
    Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanic... systems (MEMS) and microfluidic devices to robotic micro-nanomanipulati... systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies.
  • Recent Advancement in Microbial Biotechnology

    Agricultural and Industrial Approach
    • 1st Edition
    • Surajit de Mandal + 1 more
    • English
    The rapid increase in microbial resources along with the development of biotechnological methods has revolutionized the field of microbial biotechnology. Genome characterization methods and metagenomic approaches further illustrate the role of microorganisms in various fields of research. Recent Advancement in Microbial Biotechnology: Agricultural and Industrial Approach provides an overview on the recent application of the microorganisms in agricultural and industrial improvements. The purpose of this book is to integrate all these diverse areas of research in a common platform. Recent advancement in Microbial Biotechnology targets researchers from both academia and industry, professors and graduate students working in molecular biology, microbiology and biotechnology.
  • Advances in Botanical Research

    Past, Current and Future Topics
    • 1st Edition
    • Volume 100
    • English
    Advances in Botanical Research: Past, Current and Future Topics, Volume 100 in the Advances in Botanical Research series, celebrates a remarkable achievement as 100 volumes have now been published, with several others being prepared. New chapters in this monumental release include Editorial activities for Advances in Botanical Research, Revisiting ABR editing in the period 2006-2012: An exciting experience with Jean-Claude Kader, A tribute to the scientific contributions of Pierre Gadal and his laboratory, Evolution of Bacterial Phototrophy, Algae for Global Sustainability, Genomics of cyanobacteria: New insights and lessons for shaping our future, An overview of the root-knot-nematode compatible interaction, and more.
  • Endocrine-Disrupting Chemicals

    • 1st Edition
    • Volume 92
    • English
    Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • iPSCs in Tissue Engineering

    • 1st Edition
    • Alexander Birbrair
    • English
    The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs in Tissue Engineering, Volume 11 addresses how induced pluripotent stem cells (iPSCs) are being used to advance tissue engineering. Somatic cells can be reprogrammed into iPSCs by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This book will address the advances in research of how iPSCs are being used for the generation of different tissues and organs such as the lungs, trachea, salivary glands, skeletal muscle, liver, intestine, kidney, even the brain, and much more. This volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and tissue engineering and is contributed by world-renowned authors in the field.
  • Overcoming Drug Resistance in Gynecologic Cancers

    • 1st Edition
    • Volume 17
    • English
    Overcoming Drug Resistance in Gynecologic Cancers provides up-to-date information related to important gynecologic cancers and focuses on mechanisms of drug resistance, genetics, signaling, immunology, health disparities, nanotechnology, economic considerations and financial impacts. The book covers not only drug resistance but also important means to reverse resistance both in the laboratory and clinic. The book discusses topics such as lifestyle, nutrition and risk of gynecologic cancers, the financial impact of drug resistance, chemosensitizing agents and targeted therapies in cervical, endometrial and ovarian cancer, immunotherapy to overcome drug resistance, and genetic polymorphisms in gynecologic cancers. Additionally, it discusses ethnic and racial health disparity perspectives and future developments in chemosensitizing activities to reverse drug resistance in gynecologic cancers. It is a valuable resource for cancer researchers, oncologists, clinicians and other biomedical field members who are interested in new approaches to improve chemotherapy outcome in patients with gynecologic cancers.
  • Disorders of Emotion in Neurologic Disease

    • 1st Edition
    • Volume 183
    • English
    Disorders of Emotion in Neurologic Disease, Volume 183 in the Handbook of Clinical Neurology Series, informs clinicians on which neurologic diseases are likely to have a secondary effect on emotion, what to look for in diagnosis, and best practices for treatment. The book begins with an understanding of the neurological basis for emotions in order to better understand what goes awry in neurological disease. It then discusses specific neurologic diseases and disorders affecting emotion.
  • Advances in Organic Farming

    Agronomic Soil Management Practices
    • 1st Edition
    • Vijay Singh Meena + 4 more
    • English
    Advances in Organic Farming: Agronomic Soil Management Practices focuses on the integrated interactions between soil-plant-microbe-e... elements in a functioning ecosystem. It explains sustainable nutrient management under organic farming and agriculture, with chapters focusing on the role of nutrient management in sustaining global ecosystems, the remediation of polluted soils, conservation practices, degradation of pollutants, biofertilizers and biopesticides, critical biogeochemical cycles, potential responses for current and impending environmental change, and other critical factors. Organic farming is both challenging and exciting, as its practice of “feeding the soil, not the plant” provides opportunity to better understand why some growing methods are preferred over others. In the simplest terms, organic growing is based on maintaining a living soil with a diverse population of micro and macro soil organisms. Organic matter (OM) is maintained in the soil through the addition of compost, animal manure, green manures and the avoidance of excess mechanization.
  • Retinal Computation

    • 1st Edition
    • Greg Schwartz
    • English
    Retinal Computation summarizes current progress in defining the computations performed by the retina, also including the synaptic and circuit mechanisms by which they are implemented. Each chapter focuses on a single retinal computation that includes the definition of the computation and its neuroethological purpose, along with the available information on its known and unknown neuronal mechanisms. All chapters contain end-of-chapter questions associated with a landmark paper, as well as programming exercises. This book is written for advanced graduate students, researchers and ophthalmologists interested in vision science or computational neuroscience of sensory systems. While the typical textbook's description of the retina is akin to a biological video camera, the real retina is actually the world’s most complex image processing machine. As part of the central nervous system, the retina converts patterns of light at the input into a rich palette of representations at the output. The parallel streams of information in the optic nerve encode features like color, contrast, orientation of edges, and direction of motion. Image processing in the retina is undeniably complex, but as one of the most accessible parts of the central nervous system, the tools to study retinal circuits with unprecedented precision are up to the task. This book provides a practical guide and resource about the current state of the field of retinal computation.
  • Molecular Mechanisms of Nutritional Interventions and Supplements for the Management of Sexual Dysfunction and Benign Prostatic Hyperplasia

    • 1st Edition
    • Bilal Chughtai
    • English
    Molecular Mechanisms of Nutritional Interventions and Supplements for the Management of Sexual Disfunction and Benign Prostatic Hyperplasia presents the epidemiologic data linking diet with BPH and ED, along with a deep explanation on why nutritional approaches and different macronutrients may modify the pathogenesis of the disease. Coverage includes the relevance/epidemiolo... of the disease, pathophysiological events causing the disease, available therapeutic options, molecular mechanisms of action of available treatments, epidemiological and intervention studies suggesting the benefit of diet as therapeutic option for BPH and ED, and potential mechanisms of action of nutritional based approaches as treatment for BPH and ED. By combining medicine, diet and lifestyle options, this title provides a truly multidisciplinary approach to BPH and ED, making it a unique resource for those treating BPH and an irreplaceable reference guide for those in research.
  • Contamination of Water

    Health Risk Assessment and Treatment Strategies
    • 1st Edition
    • Arif Ahamad + 2 more
    • English
    Water containing significant amounts of inorganic and organic contaminants can have serious environmental consequences and serious health implications when ingested. Contamination of Water: Health Risk Assessment and Treatment Strategies takes an interconnected look at the various pollutants, the source of contamination, the effects of contamination on aquatic ecosystems and human health, and what the potential mitigation strategies are. This book is organized into three sections. The first section examines the sources of potential contamination. This includes considering the current scenario of heavy metal and pesticide contamination in water as well as the regions impacted due to industrialization, mining, or urbanization. The second section goes on to discuss water contamination and health risks caused by toxic elements, radiological contaminants, microplastics and nanoparticles, and pharmaceutical and personal care products. This book concludes with a section exploring efficient low-cost treatment technologies and remediation strategies that remove toxic pollutants from water. Contamination of Water incorporates both theoretical and practical information that will be useful for researchers, professors, graduate students, and professionals working on water contamination, environmental and health impacts, and the management and treatment of water resources.
  • Sustainable Production Technology in Food

    • 1st Edition
    • Jose M. Lorenzo + 2 more
    • English
    Sustainability is an essential part of our modern food production system. Carrying out food research that considers environmental, social, and economic factors, is a major objective for food producers and researchers. Strategic development and use of technology can greatly assist in the progression toward a more sustainable food system. Sustainable Production Technology in Food explores important scientific and practical aspects related to sustainable technologies used in all aspects of the food system. This book is organized into 13 chapters, that cover the main concepts related to sustainability and technology. Coverage includes current technology in the industry, technological developments to improve sustainability of food production (biopreservation, pulsed electric fields, high pressure processing, ultrasound, cold plasma, and nanotechnology), regulatory aspects, and future perspectives.
  • Wood Degradation and Ligninolytic Fungi

    • 1st Edition
    • Volume 99
    • English
    Wood Degradation and Ligninolytic Fungi, Volume 99 summarizes current knowledge on wood degradation by fungi. Chapters in this new release include Intracellular detoxification strategies of lignolytic fungi, Cell signaling during wood degradation, Evolution of ligninolytic systems in fungi, Diversity and distribution of lignolytic fungi, Fungal catalysts for lignin valorization: applied aspects, Expression of fungal lignocellulolytic genes in the environment, Wood degradation in grapevine disease, Imaging wood degradation, Lignin degradation by ascomycetes, and more. The increasing interest for wood decaying fungi over the past few years has sparked great potential for their use in biomass valorization, their important function in global carbon cycle, and for the damages they can cause on wood materials, hence this new release includes updates on these and related topics.
  • Chirurgie endoscopique endonasale

    • 1st Edition
    • Patron Vincent + 1 more
    • French
    La chirurgie endoscopique endonasale est une chirurgie récente, dont la réputation était, encore il y a quelques années, celle d’une « chirurgie aveugle et aveuglante » tant ses complications pouvaient être graves et fréquentes. Aujourd’hui les progrès techniques et technologiques permettent d’améliorer la plupart des pathologies nasosinusiennes avec des suites opératoires simples. Pourtant, nombre de chirurgiens limitent toujours leur pratique aux procédures élémentaires par méconnaissance des techniques actuelles. Très didactique et richement illustré, ce livre apportera au praticien toutes les connaissances anatomiques, radiologiques et techniques nécessaires pour réaliser l’ensemble des procédures endoscopiques courantes. Chaque intervention y est décrite « pas à pas », depuis la préparation de l’intervention jusqu’aux suites opératoires. Une iconographie abondante et de nombreux conseils pratiques en font un ouvrage au plus proche de l’enseignement de terrain réalisé au bloc opératoire. L’ouvrage est complété par de nombreuses vidéos en ligne
  • Big Data's Threat to Liberty

    Surveillance, Nudging, and the Curation of Information
    • 1st Edition
    • Henrik Skaug Saetra
    • English
    Big Data permeates all aspects of modern life, and while there is no shortage of potential benefits resulting from this, author Henrik Skaug Sætra argues that we must also understand the threats Big Data poses to liberty. The issues discussed in Big Data’s Threat to Liberty: Surveillance, Nudging, and the Curation of Information are related to how we are constantly under surveillance. Data is gathered from our homes, our cars, our smartphones, various devices around the house, and public sources such as facial recognition enabled camera surveillance and various websites and social networks. Furthermore, the information gathered is used to influence our actions. Detailed personality profiles are utilized in order to make us purchase products and services, or pay our taxes, through tailor-made nudges aimed at irrational and subconscious mechanisms, and delivered with a level of precision only possible with Big Data-driven algorithmic curation of data. Finally, the information we receive through various media is curated by algorithms, and even people are curated in order to satisfy our desires. By providing us with what the algorithm believes we want, we are spared from the exposure of unpleasant information, and even unpleasant people. The ideological landscapes we traverse are thus characterized by conformity, and a concomitant tyranny of popular opinion becomes ever more coercive as this occurs.The question is: How does being constantly watched, manipulated, and having our world-views shaped as just described affect our freedom? In this book it is argued that Big Data’s threat to individual liberty is routinely misunderstood and underappreciated due to (a) vagueness resulting from the concept of liberty being used without it being defined, or (b) the use of definitions based on flawed understandings of what liberty is. In this new and unique contribution to the ethics of Big Data and artificial intelligence, both these challenges are thoroughly addressed.
  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 116
    • English
    Advances in Applied Microbiology, Volume 116 continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic of microbiology, with this release focusing on the lipid production by oleaginous yeasts.
  • Photoacoustic Probes for In Vivo Imaging

    • 1st Edition
    • Volume 657
    • English
    Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Advances in Virus Research

    • 1st Edition
    • Volume 110
    • Thomas Mettenleiter + 2 more
    • English
    Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
  • Advances in Cancer Research

    • 1st Edition
    • Volume 152
    • English
    Advances in Cancer Research, Volume 152, the latest release in this ongoing, well-regarded serial, provides invaluable information on the exciting and fast-moving field of cancer research.
  • Monoclonal Antibodies

    Physicochemical Analysis
    • 1st Edition
    • Harleen Kaur + 1 more
    • English
    Monoclonal antibodies (mAbs) are naturally occurring complex biomolecules. New engineering methods have turned mAbs into a leading therapeutic modality for addressing immunotherapeutic challenges and led to the rise of mAbs as the dominant class of protein therapeutics. mAbs have already demonstrated a great potential in developing safe and reliable treatments for complex diseases and creating more affordable healthcare alternatives. Developing mAbs into well-characterized antibody therapeutics that meet regulatory expectations, however, is extremely challenging. Obstacles to overcome include the determination and development of physiochemical characteristics such as aggregation, fragmentation, charge variants, identity, carbohydrate structure, and higher-order structure (HOS). This book dives deep into mAbs structure and the array of physiochemical testing and characterization methods that need to be developed and validated to establish a mAb as a therapeutic molecule. The main focus of this book is on physiochemical aspects, including the importance of establishing quality attributes such as glycosylation, primary sequence, purity, and HOS and elucidating the structure of new antibody formats by mass spectrometry. Each of the aforementioned quality attributes has been discussed in detail; this will help scientists in researching and developing biopharmaceuticals and biosimilars to find practical solutions to physicochemical testing and characterization.
  • The Practical Guide to Clinical Research and Publication

    • 1st Edition
    • Uzung Yoon
    • English
    The Practical Guide to Clinical Research and Publication provides a comprehensive overview of the key foundations of epidemiology, statistics and epidemiological studies. This book presents the most important terms and knowledge in the field from a medical point-of-view. Sections contain numerous, clinically-oriented examples and drawings to facilitate understanding and clarify the relation to clinic and practice. The book contains many graphics and key points for easier understanding and is written using bullet points for ease of use and comprehension. It is ideal for physicians and clinical researchers who want to use it as guidance for clinical research or teaching.
  • Inter-Organellar Ca2+ Signaling in Health and Disease - Part B

    • 1st Edition
    • Volume 363
    • English
    International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.
  • Molecular Imaging

    Principles and Practice
    • 2nd Edition
    • Brian D. Ross + 1 more
    • English
    The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field.
  • Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

    • 1st Edition
    • Aristidis M. Tsatsakis
    • English
    Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment.
  • Microbial Management of Plant Stresses

    Current Trends, Application and Challenges
    • 1st Edition
    • Ajay Kumar + 1 more
    • English
    Microbial Management of Plant Stresses: Current Trends, Application and Challenges explores plant microbiota including isolated microbial communities that have been used to study the functional capacities, ecological structure and dynamics of the plant-microbe interaction with focus on agricultural crops. Presenting multiple examples and evidence of the potential genetic flexibility of microbial systems to counteract the climate induced stresses associated with their host as a part of indigenous system, this book presents strategies and approaches for improvement of microbiome. As climate changes have altered the global carbon cycling and ecological dynamics, the regular and periodic occurrences of severe salinity, drought, and heat stresses across the different regimes of the agro-ecological zones have put additional constraints on agricultural ecosystem to produce efficient foods and other derived products for rapidly growing world population through low cost and sustainable technology. Furthermore chemical amendments, agricultural inputs and other innovative technologies although may have fast results with fruitful effects for enhancing crop productivity but also have other ecological drawbacks and environmental issues and offer limited use opportunities. Microbial formulations and/or microbial consortia deploying two or multiple partners have been frequently used for mitigation of various stresses, however, field success is often variable and improvement Smart, knowledge-driven selection of microorganisms is needed as well as the use of suitable delivery approaches and formulations. Microbial Management of Plant Stresses: Current Trends, Application and Challenges presents the functional potential of plant microbiota to address current challenges in crop production addressing this urgent need to bring microbial innovations into practice.
  • Roselle

    Production, Processing, Products and Biocomposites
    • 1st Edition
    • S. M. Sapuan + 3 more
    • English
    Roselle: Production, Processing, Products and Biocomposites complies the latest findings on the production, processing, products and composites of the roselle plant. The book provides researchers with the latest information on its entire use, including fibers and fruit for any application. Subjects covered include environmental advantages and challenges, the plant as a renewable resource, economic issues such as the impact of biobased medicines, biodiesel, the current market for roselle products and regulations for food packaging materials. Sections include commentary from leading industrial and academic experts in the field who present cutting-edge research on roselle fiber for a variety of industries. By comprehensively covering the development and characterization of roselle fiber as a potential to replace conventional fiber made from petroleum-based polymers, this book is a must-have resource for anyone requiring up-to-date knowledge on the lifecycle of the roselle plant.
  • New Horizons in Evolution

    • 1st Edition
    • Solomon P. Wasser + 1 more
    • English
    New Horizons in Evolution is a compendium of the latest research, analyses, and theories of evolutionary biology. Chapters are collected from the international symposium held by the Board of Governors of the University of Haifa to honor Dr. Eviatar Nevo, founder and director of the Institute of Evolution. This book includes material written by top global scientists. Such detailed summaries and recent advances include topics like genomics, epigenetics, evolutionary theory, and the evolution of cancer. This book analyzes evolutionary biology of animals, such as lizards and subterranean mammals. It also discusses agricultural evolution, specifically the vital wheat crop in various climates and locations. Each chapter contributes the most up-to-date knowledge of evolution’s role in speciation, adaptation, and regulation. New Horizons in Evolution is a valuable resource for researchers involved in evolution, evolutionary biology, and evolutionary theory. Advanced undergraduate and graduate students in evolutionary biology courses will also find this useful due to the high expertise level and latest knowledge available through this resource. 
  • Encyclopedia of Biological Chemistry

    • 3rd Edition
    • Joseph Jez
    • English
    Encyclopedia of Biological Chemistry, Six Volume Set has always been characterized by its unique and comprehensive content. Since publication of the 2nd edition, many important discoveries have been made leading to novel concepts in several areas of biochemistry, and new technologies have advanced our understanding of key processes of life. All of these advances are included in the new and expanded third edition. With its 6 volumes, this is the most up-to-date and complete resource on biochemistry and molecular biology, provided through contributions by leading experts in the field.