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Books in Life sciences

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    • Introduction to Neuropharmacology

      • 1st Edition
      • April 24, 2014
      • Philip B. Bradley
      • English
      • Paperback
        9 7 8 0 7 2 3 6 1 2 7 1 1
      • eBook
        9 7 8 1 4 8 3 1 8 3 6 8 8
      Introduction to Neuropharmacology presents the action of drugs as it relates to nervous system. It discusses the purposes into which drugs are use (e.g. as contraceptives and anti-riot agents). It addresses the differences between physiology and pharmacology. Some of the topics covered in the book are the factors affecting responses to drugs; properties of drugs; the kinetics of drug-receptor interactions; dose-response relationship; the principles of synaptic transmission; criteria for synaptic transmitters; somatic motor system; drugs affecting neuromuscular transmission; and drugs which act post-synaptically. The venoms and toxins that affect neuromuscular transmission are covered. The subdivisions of the autonomic nervous system are discussed. The text describes the autonomic ganglion stimulants. A study of the drugs mimicking parasympathetic stimulation is presented. A chapter is devoted to the drugs with antagonist actions on adrenoceptors. Another section focuses on the clinical uses of local anaesthetic drugs and the neurotransmitters in the central nervous system. The book can provide useful information to dentists, doctors, pharmacists, neurologists, students, and researchers.

    • Conceptual Background and Bioenergetic/Mitochondrial Aspects of Oncometabolism

      • 1st Edition
      • Volume 542
      • May 23, 2014
      • English
      • Hardback
        9 7 8 0 1 2 4 1 6 6 1 8 9
      • eBook
        9 7 8 0 1 2 4 1 6 6 5 7 8
      Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as "yet another" general hallmark of cancer, accumulating evidence suggests that the metabolic alterations of each neoplasm rather represent a molecular signature that intimately accompanies, and hence cannot be severed from, all facets of malignant transformation.

    • Blood and Tissue Antigens

      • 1st Edition
      • June 28, 2014
      • David Aminoff
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 5 5 1 6
      • eBook
        9 7 8 1 4 8 3 2 8 2 4 3 5
      Blood and Tissue Antigens documents the proceedings of the International Symposium on Blood and Tissue Antigens held in Ann Arbor, Michigan on September 17-19, 1969. This book focuses on the immunogenetic and biochemical aspects of the blood and tissue antigens. The topics discussed include the genetics of blood groups; blood groups and serum phosphatase; immunogenetics of the mouse H-2 system; and glycolipids as membrane antigens. The carbohydrate composition of epithelial mucins; glycolipids in SV40 and polyoma virus transformed mouse cell lines; and metabolic variations of serum proteins and enzymes are also elaborated. This text likewise covers the action of glycosidases on erythrocytes; blood group specific oligosaccharides in urine; biosynthesis of submaxillary mucins; and genes, glycosyltransferases... and blood types. This publication is a good source for students and individuals researching on blood and tissue antigens.

    • Current Topics in Bioenergetics

      • 1st Edition
      • June 28, 2014
      • D. Rao Sanadi
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 4 5 4
      • eBook
        9 7 8 1 4 8 3 2 1 6 8 8 1
      Current Topics in Bioenergetics, Volume 4 provides information pertinent to the molecular basis for energy transduction in membranous systems. This book presents the developments of relevant techniques in the field of bioenergetics. Organized into eight chapters, this volume begins with an overview of nonequilibrium and fluorescent probes that deal with relatively unexplored areas. This text then discusses the problem of pathways and mechanisms of energy transformations in the cell. Other chapters consider the transport of ions across the plasma membrane of nearly all living cells, which is a necessary condition for the maintenance of the vital life processes. This book discusses as well that bacterial synthesis offers basic and valuable information of general significance and remarkably stimulating challenges with direct bearing on different aspects of the problem of the basic mechanisms involved in biological electron transport-coupled energy conversion. The final chapter deals with the general models for the transport of sodium and potassium. This book is a valuable resource for biologists and biochemists.

    • Regulation of Fatty Acid and Glycerolipid Metabolism

      • 1st Edition
      • May 18, 2014
      • Raymond Dils + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 6 3 4 1
      • eBook
        9 7 8 1 4 8 3 1 4 8 7 6 2
      Regulation of Fatty Acid and Glycerolipid Metabolism is a compilation of papers presented during the 11th Meeting of the Federation of European Biochemical Societies in Copenhagen in 1977. The book deals with the regulation of enzyme activity and the turnover that results from fatty acid metabolism, lipid metabolism in membranes, and disturbed fatty acid metabolism. One study presented in the book shows that cellular fatty acid synthetase levels are significantly decreased by different medium and long chain fatty acids in Candida lypolytica, a kind of yeast. The book also examines the serious incidence of increase in the rate of conversion of glucose to fatty acids when white adipose tissues from rats are exposed to insulin. The selection addresses this increase as an important example of acute hormonal regulation of fatty acid synthesis in mammalian tissues. The text also describes the enzyme adaptation to nutritional and hormonal changes and the role of lipids in membrane fusion. The book presents other studies regarding the incidence of vascular, dietary, and congenital factors on fatty acid metabolism in adipose tissue and liver that are conducted in rats. Another study suggests that hyperinsulinemia is a key factor in the development of the obesity syndrome. Microbiologists, microchemists, and laboratory researchers and scientists dealing with fat metabolism will appreciate this book.

    • Handbook of Natural Antimicrobials for Food Safety and Quality

      • 1st Edition
      • November 4, 2014
      • M Taylor
      • English
      • Hardback
        9 7 8 1 7 8 2 4 2 0 3 4 7
      • Paperback
        9 7 8 0 0 8 1 0 1 3 9 9 1
      • eBook
        9 7 8 1 7 8 2 4 2 0 4 2 2
      Natural additives are increasingly favoured over synthetic ones as methods of ensuring food safety and long shelf-life. The antimicrobial properties of both plant-based antimicrobials such as essential oils and proteins such as bacteriocins are used in, for example, edible preservative films, in food packaging and in combination with synthetic preservatives for maximum efficacy. New developments in delivery technology such as nanoencapsulation also increase the potential of natural antimicrobials for widespread use in industry. Part one introduces the different types of natural antimicrobials for food applications. Part two covers methods of application, and part three looks at determining the effectiveness of natural antimicrobials in food. Part four focuses on enhancing quality and safety, and includes chapters on specific food products.

    • Progress in Biophysics and Molecular Biology

      • 1st Edition
      • May 18, 2014
      • J. A. V. Butler + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 4 4 4 1 2
      Progress in Biophysics and Molecular Biology, Volume 32 summarizes the significant progress that has been made in the fields of biophysics and molecular biology. Topics range from metabolic regulation and transfer RNA to cellular metabolism and prokaryotic and eukaryotic ribosomes. This volume consists of five chapters and begins with a discussion of mathematical models used in the study of metabolic regulation, with emphasis on the energy metabolism of eukaryotes. The next chapter examines the possible functions of transfer RNA minor components, paying particular attention to the principle of location-function relationships. The reader is also introduced to spatial-functional correlations in cellular metabolism and highlights the role of organize multienzyme systems, along with the fundamentals of ribosome structure and function in prokaryotes and eukaryotes. A chapter that analyzes the structures and functions of transfer RNA concludes the book. This book will be of interest to scientists, students, and researchers working in the fields of biophysics and molecular biology.

    • Disorders of Mineral Metabolism

      • 1st Edition
      • May 10, 2014
      • Jack W. Coburn + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 6 6 7 4
      • eBook
        9 7 8 1 4 8 3 2 6 5 3 5 3
      Disorders of Mineral Metabolism, Volume II: Calcium Physiology is a nine-chapter text that deals with the normal function of calcium, with much emphasis on a host of intracellular functions. This volume discusses the calcium absorption, excretion, and homeostasis, as well as the hormonal modifiers of its metabolism. The role of connective tissue and bone, the major storehouse of body calcium, is reviewed in terms of collagen metabolism. This book will prove useful to biochemists, pathophysiologists, and workers in the medical field.

    • Biologically Active Amines Found in Man

      • 1st Edition
      • May 17, 2014
      • Franz Franzen + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 5 0 2 1 5
      Biologically Active Amines Found in Man: Their Biochemistry, Pharmacology, and Pathophysiological Importance deals with the biochemistry, pharmacology, and pathophysiology of biologically active amines present in the human body. Emphasis is placed on amines derived by decarboxylation of α-amino acids in human beings and some of their especially interesting metabolites. This book consists of four chapters and opens with an overview of biogenic amines and their origin, followed by a discussion on their biochemistry, pharmacology, and pathophysiology. The metabolism and inactivation of biologically active amines such as tyramine, dopamine, noradrenaline, adrenaline, tryptamine, serotonin, and histamine are examined, along with their incorporation into the body protein and their rate of turnover. The influence of biologically active amines on the function of the kidneys, microcirculation, and respiratory metabolism is also considered. Finally, illnesses in which indigenous amines have known or possible/probable pathophysiological significance are described. This monograph will be of interest to biologists, biochemists, pharmacologists, and pathophysiologists.

    • Chesley's Hypertensive Disorders in Pregnancy

      • 4th Edition
      • August 28, 2014
      • Robert N. Taylor + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 4 0 7 8 6 6 6
      • Paperback
        9 7 8 0 1 2 8 1 0 0 6 4 6
      • eBook
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      Chesley’s Hypertensive Disorders in Pregnancy continues its tradition as one of the beacons to guide the field of preeclampsia research, recognized for its uniqueness and utility. Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this the hypertensive disorders remain marginally studied and management is often controversial.The fourth edition of Chesley’s Hypertensive Disorders in Pregnancy focuses on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, and not just preeclampsia.

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