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Elsevier

Books in Life sciences

  • Personalized Cancer Medicine through Multiomics

    • 1st Edition
    • Mohammad Azhar Aziz + 1 more
    • English
    Personalized Cancer Medicine through Multiomics explores the groundbreaking integration of multiomics to transform cancer diagnosis and treatment. The book delves into how the convergence of genomics, transcriptomics, proteomics, and metabolomics offers a comprehensive understanding of cancer biology, surpassing traditional single-omics approaches. Sections detail advancements in high-throughput technologies and computational methods, including machine learning, that enable the analysis of complex cancer datasets. Additional content discusses how multiomics identifies unique molecular signatures, novel therapeutic targets, and biomarkers, facilitating precise and individualized treatment strategies, particularly for heterogeneous cancers.For academics, this book serves as an essential resource, compiling fragmented research into a single, coherent volume. It provides foundational knowledge, the latest advancements, and practical applications of multiomics in personalized medicine. Researchers will benefit from interdisciplinary approaches, real-world examples, and cutting-edge methodologies, making it an invaluable reference for advancing their work in oncology.

  • The Fauna of Australia’s Tropical Savanna Biome

    Biodiversity, Biogeography, and Conservation
    • 1st Edition
    • Alan Andersen + 1 more
    • English
    The Fauna of Australia's Tropical Savanna Biome: Biodiversity, Biogeography and Conservation considers the full range of vegetation types and freshwater systems that occur within the dominant savanna matrix in Australia's monsoonal tropics. Edited by renowned experts of tropical ecology, it provides descriptions of diversity, taxonomic, functional composition and endemism, and ecological and biogeographical questions of wide interest. Chapters explore how diversity and composition vary among different habitats in a savanna landscape and along the savanna rainfall gradient. The book also considers how distinctive savanna fauna is within Australia and compared with tropical savannas elsewhere in the world. The book considers the unique biogeographic and evolutionary history of this highly diverse and distinctive biome, building on a rich foundation of knowledge accrued over decades of research on many aspects of the region's biodiversity, conservation values, and challenges. This is an indispensable resource for students and researchers studying tropical biodiversity, as well as conservationists and land managers of Australia's tropical savanna biome and those found across the globe.

  • Pulse Breeding, Processing, Functionality, and Products

    • 1st Edition
    • Fatma Boukid + 3 more
    • English
    Pulse Breeding, Processing, Functionality, and Products reflects the shift from animal- to plant-based foods, addressing increased interest in pulses due to their higher protein contents when compared to most cereals. The book provides comprehensive coverage of a wide range of knowledge related to pulses, from breeding approaches and market landscapes to extraction and fractionization, post- treatments for improved ingredients, their nutritional and compositional qualities, advances in testing methods, and their potential industrial applications in food and pet food. With its inclusion of problems/solutions and issues-focused insights, the book's content is valuable for immediate application and for inspiring additional research. The book offers the food industry and researchers the necessary insights to know the latest developments and emerging uses of pulse ingredients. As pulses have high adaptability, versatility, and offer potentially significant contributions to the human diet and pulse ingredient flours, proteins, fibers, and starches, they are increasingly being used in food formulations, hence this book covers the topic with a wide breadth of knowledge. Challenges, including taste, color, bite, mouthfeel, and texture are also covered for innovative products.

  • Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics

    • 1st Edition
    • Lara Scheherazade Milane + 1 more
    • English
    Targeting Intercellular Communication with Nanomedicine and Advanced Therapeutics delves into the complex world of intercellular communication biology and its implications on therapeutics. This book covers all areas of intercellular communication and therapeutics in development for different forms of communication, including their role in diseases such as cancer, neurological disorders, metabolic diseases, and inflammatory/immune diseases. Sections provide an introduction, biological targets, challenges, and approaches to overcoming biological barriers and the significance of contact points and mechanisms of internalization. Specifics of tunneling nanotubes, extracellular vesicles, and the immune and non-immune interface in various diseases are covered. Furthermore, the book explores the crosstalk of different forms of intercellular communication and the implications of mitochondrial exchange in the four primary pathological areas. This is an essential resource for researchers, students, and professionals in the field of drug development and delivery. By connecting the dots between extracellular vesicles, tunneling nanotubes, and cell-cell junctions, this book serves as a foundation for further advancements in the science of intercellular communication and it's applications to new drug discovery and delivery.

  • Membrane Transporters and Drug Delivery

    A Comprehensive and Multidisciplinary Guide
    • 1st Edition
    • Elena Puris + 3 more
    • English
    Membrane Transporters and Drug Delivery: A Comprehensive and Multidisciplinary Guide is a comprehensive reference on the rapidly evolving field of membrane transporters and their role in drug delivery. The book begins with a comprehensive introduction to membrane transporters and their function, structure, and regulation mechanisms. It then moves into the impact of diseases on transporters and how this may affect pharmacokinetics. The book also presents the latest advancements in transporter-mediated drug delivery, examines the roles of both efflux and influx transporters in drug pharmacokinetics, and covers different strategies for utilizing membrane transporters for drug delivery and targeting specific tissues and cell types.It concludes with a discussion on the regulatory and industrial aspects of transporter-related projects, explores the potential of artificial intelligence in transporter and drug delivery research, and offers a glimpse into future challenges and perspectives in this field.

  • Molecular Tools and Infectious Disease Epidemiology

    • 2nd Edition
    • Betsy Foxman + 1 more
    • English
    Molecular Tools and Infectious Disease Epidemiology, Second Edition examines the opportunities and methodologic challenges in the application of modern molecular genetic and biologic techniques to infectious disease epidemiology. The application of these techniques dramatically improves the measurement of disease and putative risk factors, increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. This book presents the key points of consideration when integrating molecular biology and epidemiology.Section... discuss how using molecular tools in epidemiologic research affects program design and conduct, consider the ethical concerns that arise in molecular epidemiologic studies, and provide a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory, and in the field. The book is recommended for graduate and advanced undergraduate students studying infectious disease epidemiology and molecular epidemiology; and for the epidemiologist wishing to integrate molecular techniques into their studies.

  • Insect Pathology

    • 3rd Edition
    • Nemat Keyhani + 2 more
    • English
    Insect Pathology, Third Edition offers the most comprehensive research on the topic of insect pathology, spanning the diversity of insects with a more diverse array of microbes. This book provides a full update on new approaches for studying the genetics, development, evolution, and ecology of insect pathogens. Written by leading researchers and experts, the book includes coverage of revolutionary genome editing tools, such as CRISPR-Cas9, which have been developed for multiple insect pathogen systems and provides insights into the molecular underpinnings of insect pathogens and their hosts. This book also updates modern molecular techniques, “omics” approaches, and newly applied findings. These new and revised topics are critical for understanding current perspectives in the field, making this book a needed reference for insect pathologists, entomologists, microbiologists, mycologists, nematologists, protistologists, ecologists, and practitioners of biological control of insect pests. New and long-time students of insect pathology will also find this new edition useful.

  • Advances in Virus Research

    • 1st Edition
    • Volume 126
    • English
    Advances in Virus Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Parasitology

    • 1st Edition
    • Volume 134
    • English
    Advances in Parasitology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1st Edition
    • Thomas M. Attard
    • English
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.

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