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Elsevier

Books in Life sciences

  • The Zebrafish: Genetics, Genomics, and Transcriptomics

    • 4th Edition
    • Volume 135
    • English
    The Zebrafish: Genetics, Genomics, and Transcriptomics, Fourth Edition, is the latest volume in the Methods in Cell Biology series that looks at methods for the analysis of genetics, genomics, and transcriptomics of Zebrafish. Chapters cover such topics as gene-trap mutagenesis, genetic Screens for mutations, gene editing in zebrafish, homologous gene targeting, genome-wide RNA tomography, and developmental epigenetics and the zebrafish interactome.

  • Cold Plasma in Food and Agriculture

    Fundamentals and Applications
    • 1st Edition
    • NN Misra + 2 more
    • English
    Cold Plasma in Food and Agriculture: Fundamentals and Applications is an essential reference offering a broad perspective on a new, exciting, and growing field for the food industry. Written for researchers, industry personnel, and students interested in nonthermal food technology, this reference will lay the groundwork of plasma physics, chemistry, and technology, and their biological applications. Food scientists and food engineers interested in understanding the theory and application of nonthermal plasma for food will find this book valuable because it provides a roadmap for future developments in this emerging field. This reference is also useful for biologists, chemists, and physicists who wish to understand the fundamentals of plasma physics, chemistry, and technology and their biological interactions through applying novel plasma sources to food and other sensitive biomaterials.

  • Enzymes of Epigenetics Part B

    • 1st Edition
    • Volume 574
    • English
    Enzymes of Epigenetics: Part B, one of two new volumes in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods that are employed in the study of epigenetic regulation, including structural, biochemical, molecular, biological, cellular, computational, and systems approaches. Topics include chromatin structure and histones, posttranslational histone modification enzymes and complexes, histone modification binders, DNA modifications and nucleic acid regulators, epigenetic technologies, and small molecule epigenetic regulators and biological connections.

  • Nutraceuticals

    • 1st Edition
    • Alexandru Grumezescu
    • English
    Nutraceuticals, the fourth volume in the Nanotechnology in the Agri-Food Industry series, is an invaluable resource for anyone in the food industry who needs the most current information about scientific advances in this field. Nutraceuticals are gaining significant attention because of their apparent safety, as well as their nutritional and therapeutic uses. Scientific indications have reinforced dietary interposition as an effective implement for a healthy lifestyle. Bioactive components have been shown to exhibit antioxidant, anti-inflammatory, antimicrobial, hypocholesterolemic, hypoglycemic, anti-mutagenic, and anti-carcinogenic roles in the living system. Research professionals, professors, and students will all find this book useful.

  • Neuroimaging, Part I

    • 1st Edition
    • Volume 135
    • English
    Neuroimaging, Part One, a text from The Handbook of Clinical Neurology illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This first volume specifically covers a description of imaging techniques used in the adult brain, aiming to bring a comprehensive view of the field of neuroimaging to a varying audience. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, and the entire field is moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to this new horizon in the study of neurological disorders.

  • Trace Amines and Neurological Disorders

    Potential Mechanisms and Risk Factors
    • 1st Edition
    • Tahira Farooqui + 1 more
    • English
    Trace Amines and Neurological Disorders: Potential Mechanisms and Risk Factors explores trace amines which, under normal conditions, are present in the mammalian brain and peripheral nervous tissues at very low (nanomolar) concentrations. However, in a diverse array of human pathologies ranging from substance abuse, depression, attention deficit hyperactivity disorder, eating disorders, schizophrenia, and other neurological and neuropsychiatric diseases, the levels of trace amines are unusually high with an imbalance in their functions. Furthermore, the rapid turnover of trace amines is evidenced by their dramatic increases following treatment with monoamine oxidase inhibitors (MAOI) or deletion of the MAO genes. This suggests that the concentration of trace amines may be considerably higher at neuronal synapses than predicted by steady-state measures, implicating some pathophysiological role. Therefore, understanding molecular mechanisms and developing selective agonists and antagonists for trace amine-associated receptors (TAARs) has become a good approach for treating these diseases. Although the effects of trace amines at low physiological concentrations in mammalian species have been difficult to demonstrate, they may serve to maintain the neuronal activity of other monoamine neurotransmitters by possessing postsynaptic modulatory effects, particularly dopamine and serotonin, within defined physiological limits. Such an effect of trace amines makes them ideal candidates for the development of novel therapeutics for a wide range of human disorders. This book presents up-to-date, cutting-edge, and comprehensive information on the link between trace amines and neurological disorders.

  • Neuroimaging, Part II

    • 1st Edition
    • Volume 136
    • English
    Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders.

  • Synthetic Biology and Metabolic Engineering in Plants and Microbes Part A: Metabolism in Microbes

    • 1st Edition
    • Volume 575
    • English
    Synthetic Biology and Metabolic Engineering in Plants and Microbes: Part A, the new volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods, synthetic biology, and metabolic engineering in plants and microbes, and includes sections on such topics as the uses of integrases in microbial engineering, biosynthesis, and engineering of tryptophan derived metabolites, regulation and discovery of fungal natural products, and elucidation and localization of plant pathways.

  • Aquaculture Virology

    • 1st Edition
    • Frederick S.B. Kibenge + 1 more
    • English
    To date textbooks on viruses infecting fish, crustaceans and molluscs, the three main aquatic animal farmed groups, have been on the whole “diseases-centric” and individual viral diseases selected based on “epizoo-centric” approaches with little to no coverage of the basic biology of the viruses, in contrast to textbooks on viruses infecting terrestrial – farmed, pet, and free-range (wild) – animals and humans. Despite considerable advances in animal virology in recent years coupled with an economically important global aquaculture industry, knowledge of viruses of animal aquaculture is still sparse and in some cases outdated although these viruses are closely related to well-known virus families. The last book in fish virology (Fish viruses and fish viral diseases 1988, Wolf, K.) was published in the 1980s. A lot of work has been done on fish viruses and many new aquatic animal viruses continue to be discovered. Aquaculture Virology provides the current state of knowledge of aquatic animal viruses within the current virus classification and taxonomic context thereby allowing the reader to draw on the principles of general virology. This book is a systematic and concise resource useful to anyone involved with or looking to move into aquaculture and fisheries. Clinical veterinarians, aquaculture disease practitioners, biologists, farmers, and all those in industry, government or academia who are interested in aquatic animal virology will find this book extremely useful.

  • Ion Channels in Health and Disease

    • 1st Edition
    • Geoffrey S. Pitt
    • English
    Ion Channels in Health and Disease provides key insight to allow researchers to generate discoveries across disease states. A single resource that integrates disparate areas of biology and disease ion channel biology, this publication includes cross-referencing for disease, channels, and tissues. Offers a broad view of research of interest to early and experienced researchers across biological and biomedical research.

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