Endocannabinoids
- 1st Edition, Volume 125 - November 26, 2015
- Editors: Loren Parsons, Matthew Hill
- Language: English
- Hardback ISBN:9 7 8 - 0 - 1 2 - 8 0 1 2 7 8 - 9
- eBook ISBN:9 7 8 - 0 - 1 2 - 8 0 1 3 7 6 - 2
Endocannabinoids, the latest volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into the neurobiology… Read more
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- The endocannabinoid system is the biological system in the body which mediates the effects of cannabis
- Provides an up to date, comprehensive overview of the biological functions of endocannabinoid signaling in the brain and how it regulates an array of processes, such as brain development, reward, emotion and pain
People working in basic neuroscience, purinergic science, neurology and psychiatry; investors and businesses in pharmaceutical R&D; medical doctors and care givers
Chapter One: The Endocannabinoid Signaling System in the CNS: A Primer
- Abstract
- 1 Introduction
- 2 The Endocannabinoids
- 3 Endocannabinoid Receptors
- 4 CB1R and Retrograde Regulation of Synaptic Activity
- 5 Summary
- Acknowledgments
Chapter Two: Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and Emotional Behavior Development
- Abstract
- 1 Adolescence and Pubertal Maturation
- 2 The Neurobiology of Stress
- 3 Adolescent HPA Axis Development
- 4 The Developmental Influence of Gonadal Hormones on the HPA Axis
- 5 The Endocannabinoid System
- 6 Endocannabinoid System Regulation of the HPA Axis in Adulthood
- 7 Ontogeny of the Endocannabinoid System
- 8 Adolescent HPA Axis Function: A Regulatory Role for the Endocannabinoid System?
- 9 Concluding Remarks
- Acknowledgments
Chapter Three: The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestinal Tract
- Abstract
- 1 Introduction
- 2 The Enteric Nervous System and the Brain–Gut Axis
- 3 The Endocannabinoid System
- 4 Endocannabinoid Signaling Mechanisms
- 5 Other Receptors, Agonists, and Antagonists
- 6 Endocannabinoid Tone
- 7 Cannabinoid Receptor Metaplasticity in the ENS
- 8 Cannabinoid Receptor Properties
- 9 Enteric Glia
- 10 Neurotransmission in the ENS and GI Tract
- 11 Brain–Gut Axis
- 12 The Endocannabinoid System of the ENS in GI Inflammation
- 13 Summary and Future Directions
- Disclosures
Chapter Four: Endocannabinoid Mechanisms Influencing Nausea
- Abstract
- 1 Endocannabinoids in Acute Nausea
- 2 Endocannabinoids in Anticipatory Nausea
- 3 Conclusions
Chapter Five: Endocannabinoid Regulation of Neuroendocrine Systems
- Abstract
- 1 The Endocannabinoids and Their Receptors
- 2 Cannabinoid Regulation of the Neuroendocrine Stress Response
- 3 Endocannabinoid Regulation of Energy Homeostasis
- 4 Endocannabinoids and Fluid Homeostasis
- 5 Endocannabinoid Regulation of Reproduction
Chapter Six: The Role of the Brain's Endocannabinoid System in Pain and Its Modulation by Stress
- Abstract
- 1 Introduction
- 2 The Endocannabinoid System
- 3 The Endocannabinoid System in the Brain Regulates Pain
- 4 The Modulation of Pain by Stress: Role for the Brain's Endocannabinoid System
- 5 The Role of the Endocannabinoid System in the Rostral Ventromedial Medulla in Pain, Stress-Induced Analgesia, and Stress-Induced Hyperalgesia
- 6 The Role of the Endocannabinoid System in the Periaquaductal Gray in Pain, Stress-Induced Analgesia, and Stress-Induced Hyperalgesia
- 7 The Role of the Endocannabinoid System in the Amygdala in Pain, Stress-Induced Analgesia, and Stress-Induced Hyperalgesia
- 8 The Role of the Endocannabinoid System in the Prefrontal Cortex in Pain, Stress-Induced Analgesia, and Stress-Induced Hyperalgesia
- 9 Less Characterized Supraspinal Endocannabinoid Mechanisms in Pain Modulation
- 10 Concluding Remarks
- Acknowledgments
Chapter Seven: Endocannabinoid Signaling in Motivation, Reward, and Addiction: Influences on Mesocorticolimbic Dopamine Function
- Abstract
- 1 Introduction
- 2 The Neurobiology of Reward
- 3 The Influence of Endocannabinoid Signaling on Reward
- 4 The Role of the Endocannabinoid System in Motivation
- 5 Drug Addiction and the Endocannabinoid System: A Reciprocal Modulation of Synaptic Plasticity
- 6 Concluding Remarks
- Acknowledgments
- No. of pages: 352
- Language: English
- Edition: 1
- Volume: 125
- Published: November 26, 2015
- Imprint: Academic Press
- Hardback ISBN: 9780128012789
- eBook ISBN: 9780128013762
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Loren Parsons
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