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Books in Life sciences

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  • Lipid Analysis in Biology, Health, and Disease

    • 1st Edition
    • Sanjoy K. Bhattacharya
    • English
    Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.

  • Generative Artificial Intelligence and Ethics for Healthcare

    • 1st Edition
    • Loveleen Gaur + 1 more
    • English
    Generative Artificial Intelligence and Ethics for Healthcare conducts a deep dive into the potential issues and challenges associated with Generative AI applications. The book begins with foundational concepts of generative AI and then explores ethical theories, including specific case studies in healthcare, and concludes with discussions on policy and future implications. Written for healthcare professionals, policymakers, academics and AI developers, by authors who have a thorough understanding of AI and machine learning in the healthcare.

  • Domestic and Wild Sheep

    Origins, Genetics and Breeding
    • 1st Edition
    • Menghua Li + 1 more
    • English
    The Characterization of Genus Ovis: Genetics, Domestication and Behavior delves into the diverse world of wild and domesticated sheep. This book offers comprehensive information on the genetics, evolution, diversity, behavior, expansion, breeding, and domestication of sheep. It is a detailed characterization of this ecologically and commercially significant genus. Written by experts who have hosted the World Sheep Conference four times, the book is systematically structured into four sections to guide readers through the various Ovis species, their biological characteristics, genetic markers, and their significance to human populations.Furtherm... it offers new insights into the functional genetics of sheep species, their migrations and expansions in connection with human history, and guidance on successful breeding and husbandry. The book is organized for accessibility to student, academic, and professional audiences, making it an indispensable resource for anyone interested in animal evolution, diversity, behavior, and husbandry.

  • Federated Learning in Metaverse Healthcare

    Personalized Medicine and Wellness
    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Federated Learning in Metaverse Healthcare: Personalized Medicine and Wellness explores the integration of the metaverse with healthcare, offering immersive experiences and personalized care. The book introduces federated learning, emphasizing its advantages over traditional centralized machine learning in healthcare. It provides a historical context and discusses the technological advancements that led to the emergence of metaverse healthcare. Privacy-preserving methods crucial for protecting sensitive healthcare data within federated learning environments are also examined, underscoring the importance of secure communication protocols. Other important points include the transformation of healthcare delivery through virtual environments, remote consultations, and immersive experiences.The role of telemedicine in facilitating remote diagnostics and consultations via virtual platforms, and the applications of augmented reality wearables for real-time health monitoring and wellness tracking are detailed. Additionally, the book discusses federated learning's ability to deliver personalized treatment plans tailored to individual patient needs, its role in predictive modeling for disease risks and prevention, as well as virtual health coaches offering personalized guidance for wellness management. The challenges and ethical dilemmas of metaverse healthcare and federated learning, along with potential solutions, are also considered.

  • Protein Structure Prediction and Analysis

    • 1st Edition
    • Volume 147
    • English
    Protein Structure Prediction and Analysis, Volume 146 offers a comprehensive exploration of the methodologies, tools, and techniques utilized in the prediction and analysis of protein structures. The book delves into the fundamental principles of protein folding, modeling, and computational simulations, providing insights into the intricate process of predicting the three-dimensional structures of proteins. Sections in this new release include coverage of Current approaches for protein structure prediction and design, Protein Modelling, Prediction servers and applications in molecular modelling, Toward accurate in silico prediction of antigen binding affinities in antibody engineering, Molecular Blueprints: Guiding Drug Discovery through Protein Structure Analysis, and much more.Additional sections focus on Protein Structure Prediction Using Dynamic Speciation Evolutionary Algorithm with Problem Information Aggregation, Tau protein structure and dynamics, Tau interacts with G-protein coupled receptors (GPCRs), How to accurately predict nanobody structure: Classical physics-based simulations or deep learning approaches, Medicinal Chemistry-based Novel Therapeutics for Tauopathies in Alzheimer’s Disease, Mapping the Pathogenic Nexus: Gene Overlap and Protein Interaction Networks in Alzheimer's and Breast Cancer as a Precursor to Protein Structure Prediction and Analysis, and much more.

  • Nanotheranostics and Precision Oncology

    • 1st Edition
    • Ramish Riaz + 4 more
    • English
    Nanotheranostics and Precision Oncology delves into the merging fields of cancer research and nanotechnology, offering a thorough review of the latest advancements in precision oncology. It begins with an exploration of cancer biology, illuminating the genetic foundations of oncogenesis alongside the cellular and molecular mechanisms driving cancer progression, metastasis, and drug resistance. This resistance remains the foremost challenge in cancer care. Across 28 chapters, the book addresses precision medicine's role in overcoming drug resistance, the importance of biomarkers, the interpretation of genetic analyses, and the shift toward personalized oncology.In addition, the book examines nanotheranostics' applications and mechanisms in cancer diagnosis and treatment, integrating them with precision oncology. It outlines the design, mechanism, and impact of nanoprecision medicine in cancer management. The final section considers the future of nanotheranostics in precision oncology and the challenges of translating these innovations from research to clinical practice. This comprehensive guide serves students, clinicians, researchers, and the pharmaceutical industry involved in nanomedicine, oncology, molecular biology, and precision medicine.

  • Advances in Food and Nutrition Research

    • 1st Edition
    • Volume 116
    • English
    Advances in Food and Nutrition Research, Volume 116 presents the most recent developments in food science, focusing on the latest advances in understanding fundamental mechanisms and control solutions for lipid oxidation in meat. It delves into the interactions of cold plasma with food ingredient functionality, examines plant-based milk's health impacts, and critically analyzes the nutritional consequences of emerging processed foods. Additionally, the book addresses the formation and reduction of polycyclic aromatic hydrocarbons in processed foods and explores innovative technologies for meat waste valorization and the detection of bacterial pathogens using biosensors and phage biocontrol.Titles of notable chapters include Lipid Oxidation in Meat: From Fundamental Mechanisms to Latest Control Solutions, Cold Plasma interactions with Food Ingredients Functionality, Current Research on Plant-Based Milk and Impact on Health, Emerging Processed Food and its Nutritional Consequences: A Critical Analysis, and Polycyclic Aromatic Hydrocarbons in Processed Foods: Formation, Occurrence, Analysis and Reduction.

  • Biliary Tract Neoplasms

    • 1st Edition
    • Timothy M. Pawlik + 1 more
    • English
    Biliary Tract Neoplasms is a state-of-art reference of the multimodality management of bile duct cancer written by leaders in the field. As targeted therapy and clinical trials in this field are exploding, and the incidence of the disease is increasing, now is the time to address the topic in practical manner. This reference addresses surgical approaches to biliary neoplasms, targeted personalized systemic approaches to biliary neoplasms, and other treatment modalities such as radiotherapy and ablation. It is intended for scientists, researchers, clinicians, practicing surgeons, surgical oncologists, transplant surgeons as well as fellows/residents in the surgical space.The book's translational nature and impact of basic science findings that have informed targeted therapy for biliary neoplasms provide the very latest data on surgery, medical, imaging, and multi-modality care of biliary neoplasm to educate and inform care of this patient population.

  • Plant-Based Drug Discovery

    Unveiling Molecular Targets for Metabolic Conditions
    • 1st Edition
    • Mamta Bisht + 2 more
    • English
    Plant-Based Drug Discovery: Unveiling Molecular Targets for Metabolic Conditions provides an in-depth examination of the molecular mechanisms of phytochemicals and their potential in treating metabolic diseases. This comprehensive guide begins with an introduction to the prevalence and impact of metabolic disorders, emphasizing the significant role of phytochemicals in their management. The book delves into scientific concepts and research findings, offering valuable insights for researchers and healthcare professionals in the fields of molecular biology, biochemistry, pharmacology, and biotechnology. Chapters cover various crucial topics such as oxidative stress, epigenetic mechanisms, and mitophagy.In addition, they explore the targeting of molecular chaperones and the molecular targets of plant nutraceuticals for treating obesity, cardiovascular disease, and type 2 diabetes. The book also addresses technological advances, including AI and nanotechnology, highlighting opportunities and challenges in improving the use of plant molecules for metabolic disorder treatments. It serves as an essential resource for those engaged in drug discovery and related areas.

  • Animal Models of Disease Part D

    • 1st Edition
    • Volume 197
    • English
    Animal Models of Disease, Part D, Volume 197 in the Methods in Cell Biology series presents significant advancements in understanding disease mechanisms through animal models. This volume features chapters on timely topics such as characterizing tumor-infiltrating group 1 innate lymphoid cells in PyMT breast tumors and using zebrafish to unravel the molecular mechanisms of Alzheimer’s disease. The book also covers colitis mouse models and appropriate models for studying diabetes pathophysiology, demonstrating its comprehensive approach to current research.Additional sections cover evaluating polyglutamine protein aggregation in transgenic Caenorhabditis elegans models of Huntington's disease and studying tumor responses to radioimmunotherapy in ovarian cancer models. It also highlights the antimicrobial regime for gut microbiota depletion in mice and the biodistribution of metallic nanoparticles for lymphoma studies. This book is an essential resource for researchers seeking to explore disease mechanisms and therapeutic approaches through animal models.

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