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Books in Life sciences

  • Biology of Fatty Acids

    Biochemical, Nutritional and Pharmacological Functions
    • 1st Edition
    • E. P. Meran Keshawa + 1 more
    • English
    Biology of Fatty Acids: Biochemical, Nutritional, and Pharmacological Functions offers an in-depth exploration of the vital roles fatty acids play in human health. From their influence on metabolism and immune functions to their potential in disease prevention and treatment, this book covers a wide range of topics. With contributions from leading experts, it examines the latest research on fatty acids in nutrition, emerging plant-based sources, and their pharmacological potential in treating conditions like neurodegenerative diseases and cancer. A must-read for scientists, healthcare professionals, and anyone interested in the transformative impact of fatty acids on human health.

  • Endothelium and Cardiovascular Diseases

    Vascular Biology and Clinical Syndromes
    • 2nd Edition
    • Protasio L. Da Luz + 3 more
    • English
    Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia... diabetes, and hypertension are discussed at length.With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health.

  • Flexible Constant-Force Robotic Manipulators

    Design and Applications
    • 1st Edition
    • Qingsong Xu
    • English
    Flexible Constant-Force Robotic Manipulators: Design and Applications offers a comprehensive survey of recent designs of flexible constant-force robotic manipulators, focusing on their applications in biomedical fields. The book presents innovative design approaches, including flexure mechanisms and bistable beams that enable compliant constant-force and constant-torque motion. Key topics include constant-force gripper designs for biological sample manipulation, polishing end-effectors for robotic manufacturing, and manipulators for ultrasound imaging that maintain consistent contact with the human body. This book defines the roles of these manipulators in biological cell manipulation, part polishing, ultrasound imaging, and healthcare, aiming to improve the quality of life. It is suitable for beginners, providing fundamental principles of compliant mechanism-based flexible robotics, and for advanced audiences, offering in-depth descriptions of state-of-the-art techniques. Readers will gain insights into the current limitations and future directions of robotic technology in precision medical treatment, making it a valuable resource for both newcomers and experienced professionals in the field.

  • Bacterial Efflux Systems

    • 1st Edition
    • Volume 724
    • English
    Bacterial Efflux Systems, Volume 722 covers experimental and computational approaches to study the function, structure, and mechanism of bacterial efflux pump systems. The methods covered include preparation of samples for structural and functional analyses and in vivo activity analysis. Specific chapters in this release cover Efflux pump functional assays, NMR and functional analysis efflux pumps, Methods for saturation mutagenesis and functional characterization, Cooperation and functional interplay between pumps, Mapping interactions, HDX-MS, and much more.Other sections cover Recombinant Expression and purification, Reconstitution of a RND efflux pump in different artificial membranes for a structural biology approach, Reconstitution of rnd and mfs efflux pumps for structural biology, CusCBA system, Expression and purification of efflux pumps of Gram positives, Expression and purification of efflux pumps of archaea, ABC transporters: BmrA preparation for NMR and PatA/PatB in peptidisc, In situ structural analysis of efflux assemblies by cryoET, Molecular dynamics simulations, and so much more.

  • Recent Advances in Hemodynamics and Blood Mimetics

    • 1st Edition
    • João Mário Rodrigues Miranda + 4 more
    • English
    Recent Advances in Hemodynamics and Blood Mimetics is a comprehensive compilation of recent developments in biofluid mechanics and biomimetics, covering topics such as numerical modeling, biomedical applications of microfluidics, biomimetic flows, biomedicine applications, and organ-on-chip technology. The book explores blood hemodynamics at different scales, including application to diseases, the relationship between blood biomechanics and rheology, the mimetization of blood properties at arterial and capillary level, including the study of blood mechanical and flow properties, flow and surface properties of blood cells, and mimetization of these same properties in fluid/particle systems.These concepts are applied to the development of organ-on-chip to improve the replication of biological processes in the human body. The book organizes recent knowledge on hemodynamics and blood mimetics and is representative of the different lines of research in the field, showing an integrated view of blood biomechanics encompassing all scales to create a valuable resource where different research lines can be found and their principles understood.

  • Imaging Blood-Brain Barrier Dysfunction in Brain Disorders

    • 1st Edition
    • Danny J.J. Wang + 1 more
    • English
    Imaging Blood-Brain Barrier Dysfunction in Brain Disorders delves into the intricate structure and function of the blood-brain barrier (BBB), examining its essential role in the pathogenesis of various brain disorders. The book offers a comprehensive overview of cutting-edge medical imaging technologies for visualizing BBB function, both in a healthy state and under diseased conditions. Readers will gain an in-depth understanding of how the BBB influences normal brain function, including aspects such as aging and sleep, and how its dysfunction is linked to serious neurological conditions.Furthermo... the book explores BBB anomalies in brain disorders like stroke, traumatic brain injury, cerebral small vessel disease, Alzheimer's disease, and sleep apnea. It highlights modern medical imaging technologies, such as MRI, for observing BBB function in vivo. It emphasizes the importance of BBB imaging for monitoring and potentially curing brain disorders, and discusses its potential in the early detection of neurological disorders, allowing for timely and effective treatment strategies.

  • Nanodiagnostics to Identify and Detect Microbial Infections and Antimicrobial Resistance

    Volume 1 - Nanotheranostics, Microbial Infections, and Antimicrobial Resistance
    • 1st Edition
    • Divakar Sharma + 1 more
    • English
    Nanodiagnostics to Identify and Detect Microbial Infections and Antimicrobial Resistance: Volume One, Nanotheranostics, Microbial Infections, and Antimicrobial Resistance offers a comprehensive understanding of the global problem of antimicrobial resistance (AMR) and provides insights into the various aspects of AMR and how nanodiagnostics can be utilized to combat it. This volume discusses the development of nanotechnologies for detecting and diagnosing microbial resistant pathogens and explores a range of nano-inspired diagnostics, including biosensors, microfluidic-assiste... devices, nanorobotics, and nanocapsules.This book encompasses contributions from experts in the field, making it a valuable resource for researchers, academics, graduate students, industry professionals, and clinicians in microbiology, nanotechnology, and infectious diseases. It aids in early detection and identification of antimicrobial resistance, offering innovative solutions to combat this global challenge.

  • Novel Bioproducts through Metabolic Engineering of Secondary Metabolites

    • 1st Edition
    • Yogesh K. Ahlawat + 3 more
    • English
    Novel Bioproducts through Metabolic Engineering of Secondary Metabolites provides comprehensive coverage of the latest developments in metabolic engineering and secondary metabolites, along with their roles in industrial product development. Sections cover the pivotal role secondary metabolites play in nature, their diverse classes, their significant applications in industry and medicine, and the fundamentals of metabolic engineering. Additional coverage includes biosynthetic pathways of secondary metabolites, strain development and optimization, rational design of pathway modifications, industrial enzymes and chemicals from metabolic engineering, and cutting-edge tools and technologies in metabolic engineering. The book concludes with a roadmap for the future of metabolic engineering, exploring emerging trends such as CRISPR and genome editing, artificial intelligence applications, and the evolving landscape of synthetic biology and bioeconomy.

  • Phytochemicals and Gut Health

    Evidence and Opportunities for Gastrointestinal Management
    • 1st Edition
    • Sachchida Nand Rai + 2 more
    • English
    Phytochemicals and Gut Health: Evidence and Opportunities for Gastrointestinal Management highlights specific plant phytochemicals, their bioactive compounds, and the influence they have on the gut-brain axis. By exploring sources, production, mechanisms of action, and clinical applications, the book uncovers how certain bioactives can optimize health and improve gastrointestinal diseases while reducing the side effects and limited efficacy of current medical treatments. The book's authors identify different classes of plant-based phytochemicals such as phenolic metabolites, alkaloids, terpenoids, and glucosinolates while demonstrating a better understanding of the gut-nutraceutical axis that can improve microbiota for GI disorders, and more. Readers will also gain important perspectives on mechanisms of action and the synergistic effects phytochemicals have on cardiovascular and neurological health.

  • Functionalized Drug Delivery Systems

    • 1st Edition
    • Umesh Gupta + 1 more
    • English
    Functionalized Drug Delivery Systems delves into the potential of various functionalized drug delivery systems, such as polymeric micelles, dendrimers, metallic nanoparticles, and SMEDDS. It offers a comprehensive guide from basic concepts to advanced surface engineering techniques. The book covers liposomes, dendrimers, metal nanoparticles, polymeric micelles, niosomes, and ethosomes, concluding with a chapter on the regulatory framework. This invaluable resource is perfect for pharmaceutical researchers and graduate students keen on advancing their understanding and application of these innovative drug delivery methods. The book also provides consolidated literature reviews, making it a foundational text for new researchers.Its chapters are dedicated to specific techniques, offering detailed insights into each method. Readers will gain knowledge on improving drug absorption and targeted delivery, supported by practical examples and case studies. The final chapter on regulatory frameworks ensures compliance and best practices in developing functionalized drug delivery systems. This book is an essential read for anyone in the field of pharmaceutical research.

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