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Elsevier

Books in Life sciences

  • Chalcones

    From Drug Discovery to Pharmaceutical Applications
    • 1st Edition
    • Simone Carradori + 2 more
    • English
    Chalcones: From Drug Discovery to Pharmaceutical Applications serves as a comprehensive reference on chalcones, detailing their natural occurrence, synthetic methods, and therapeutic applications. The book provides both novice and experienced researchers with the foundational knowledge necessary to advance their work in this area. Sections cover the natural sources of chalcones, various extraction methods, structural characterization techniques, synthesis, and their role in organic chemistry and metal complexes, while also addressing pharmacokinetic properties, toxicity, and the medicinal uses of chalcones, including their effectiveness against viruses, bacteria, cancer, and neurodegenerative diseases. Final sections explore chalcone-containing products, drug formulation strategies, and clinical trials involving chalcone-based drug candidates. This reference is an essential resource for pharmaceutical researchers, providing critical insights into the applications and potential of chalcones in drug development and therapeutic interventions.

  • Computer-Aided Drug Design in Modern Drug Discovery

    • 1st Edition
    • Yinuo Wu + 2 more
    • English
    Computer-Aided Drug Design in Modern Drug Discovery offers an in-depth exploration of CADD, featuring real-world case studies and practical examples that empower researchers to effectively harness this technology in drug discovery and development. Exploring the intricacies of CADD, the book comprises several key chapters, beginning with an introduction to its methods and evolution that is followed by a thorough examination of the integration of artificial intelligence in drug design. Subsequent chapters cover various CADD approaches, including ligand-based, structure-based, and fragment-based design, alongside AI-driven compound generation and drug screening.The book also showcases a selection of marketed drugs developed with CADD or AI, such as Captopril, Tirofiban, and Crizotinib, providing invaluable insights into the successes and challenges faced in real-world applications. Finally, the discussion of emerging trends and future directions in CADD and AI highlights the ongoing evolution of these methodologies and their integration with traditional drug development processes.

  • Smart Wearable IoT

    Principles and Implementation of Development Modules with Wireless Biomedical SOC
    • 1st Edition
    • Shuenn-Yuh Lee + 1 more
    • English
    Smart Wearable IoT: Principles and Implementation of Development Modules with Wireless Biomedical SoC focuses on the development of intelligent wearable technology integrated with the Internet and various platforms. The book provides detailed guidance on building a user-friendly development platform that features intelligent wearable systems, including bio-signal SoCs/modules, user-friendly websites/apps, and artificial intelligence (AI) systems on edge/cloud. By exploring specific case studies, such as the ECG-based fatigue analysis system, readers will gain fundamental knowledge in biosignal acquisition and processing.This hands-on approach enables users to understand the integration of digital signal processing and artificial intelligence in analyzing physiological data, ultimately enhancing their skills in developing innovative wearable solutions.

  • Ion Channels in Cellular Pathophysiology Part A

    • 1st Edition
    • Volume 97
    • English
    Ion Channels in Cellular Pathophysiology, Part A, Volume 97 in the Current Topics in Membranes series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Possible therapeutic effects of essential oils on Na channels in experimental diabetic neuropathy, Modulation of ion channels by Group I metabotropic glutamate receptors, ATP-sensitive potassium channels in neurons: roles in and beyond metabolic control, Chemically induced cardiotoxicity: role of voltage dependent ion channels, Thyroid Hormone Deficiency-Induced Cardiac Ion Channel Dysfunction: Molecular Mechanisms and Arrhythmic Implications, and much more.Additional chapters discuss Pathophysiological Insights into Ion Channel Dysregulation and Electrical Remodeling in Cardiac Cells During Trypanosoma cruzi Infection, Targeting Sodium Channels in Neuroblastoma: Implications for Cellular Physiology, Breast cancer and voltage ion channels, Alpha-helical charged peptides a new concept of NaV gating modifiers, Nerve electrophysiological alterations in experimental diabetic neuropathy, and Cardioprotective effect of natural products on doxorubicin-induced acute cardiotoxicity and cardiac ischemia-reperfusion injury.

  • Advancing Biotechnology and Environmental Science Through Sustainable Innovations in Green Chemistry

    • 1st Edition
    • Volume 20
    • Usama Afzal + 2 more
    • English
    Advancing Biotechnology and Environmental Science Through Sustainable Innovations in Green Chemistry explores the transformative potential of green chemistry in addressing critical challenges in healthcare and environmental fields. The book provides a comprehensive guide on integrating sustainable innovations into various industries, promoting resource-saving processes and reducing waste to enhance environmental sustainability. With a strong focus on practical applications, the book delves into the development of environmentally-frie... materials and technologies, such as biodegradable polymers and advanced nanostructures. It highlights how these innovations can significantly improve environmental and health outcomes through detailed case studies and real-world examples.Sections cover medical, environmental applications, and environmental science. Each chapter includes visual elements like flowcharts, step-by-step procedures, and comparison tables, thus enhancing accessibility and retention of information. This book is an invaluable resource for scientists, researchers, and practitioners in chemistry, medicine, and environmental science.

  • Updates in Adrenal Disorders, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 55-2
    • Smita B. Abraham
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editor Dr. Smita B. Abraham brings her considerable expertise to the topic of Updates in Adrenal Disorders. Top experts discuss the latest developments in diagnosis and management of adrenal disorders, including topics such as diagnosis and management of adrenocortical carcinoma; management of adrenal tumors in pregnancy; autonomous cortisol secretion; primary bilateral macronodular adrenal hyperplasia; evaluation and management of primary hyperaldosteronism; and more.

  • Designer Crops

    Implications of Artificial Intelligence and Modern Biotechnological Methods
    • 1st Edition
    • Santosh Kumar Upadhyay
    • English
    Designer Crops: Implications of Artificial Intelligence and Modern Biotechnological Methods explores the global impact of environmental challenges and climate change on crop productivity. This comprehensive guide reveals how abiotic and biotic stresses and shifting climatic conditions have significantly affected traditional cropping systems and crop yields worldwide. This book discusses designer crops and climate-resilient and super cropping systems by applying diverse information from biotechnology, crop breeding, machine learning, and automation in agriculture. It showcases the evolution of technologies such as high-throughput genome sequencing, artificial intelligence, and precision breeding, revolutionizing crop design for enhanced disease resistance, nutritional value, and increased yields.In addition, it examines modern biotechnological tools and speed breeding strategies, offering a glimpse into the promising future of super crop development. Contributions from leading global experts on artificial intelligence in agriculture, machine learning for smart agricultural practices, and climate-resilient cropping strategies make this book a must have for upper-level undergraduate students in the fields of crop science, biotechnology, and sustainable agriculture. It will also be useful for researchers and professionals working in food technology, agricultural automation, and environmental consulting.

  • Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment

    • 1st Edition
    • Volume 169
    • English
    Innovative Nanotechnology: Transforming Skin Cancer Diagnosis and Treatment, Volume 169 in the Advances in Cancer Research series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this new release include an Introduction to Nanotechnology in Dermatology, Basics of Skin Cancer: Types, Diagnosis, and Current Challenges, Current Challenges in Skin Cancer Diagnosis and Treatment, Nanocarriers for Drug Delivery in Skin Cancer, Nanotechnology in Skin Cancer Diagnosis, Therapeutic Nanoparticles and Targeted Therapy, and much more.Additional chapters cover Nanotechnology in Photodynamic and Photothermal Therapy for Skin Cancer, Challenges in Translating Nanotechnology from Research to Clinical Practice, Nanotechnology and Immunotherapy Synergies in Skin Cancer, Patient-Centric Approaches and Personalized Nanomedicine in Skin Cancer, The Role of Theranostics and Nanotheranostics in Skin Cancer Management, Preclinical and Clinical Trials in Nanotech Skin Cancer Treatment, Safety, Ethical, and Regulatory Considerations in Nanotechnology for Skin Cancer, and many more interesting chapters on topics of current interest.

  • The Roadmap of Research

    A Guide to Understanding and Writing a Medical Study
    • 1st Edition
    • Vincenzo Giordano + 3 more
    • English
    The Roadmap of Research: A Guide to Understanding and Writing a Medical Study helps readers easily grasp the context, methodologies, findings, and implications of research studies, build on previous work, avoid redundancies, and identify areas where new studies can contribute significantly. The book enables researchers to innovate, propose new ideas, and design studies that contribute novel perspectives or methodologies to the field. Each step in this roadmap plays a pivotal role in the research process, from building a foundation of knowledge through reading and understanding, to generating new ideas through critical thinking, and finally, disseminating findings through clear and effective writing.

  • The Microbiome and Cancer Treatment

    Overcoming Resistance and Enhancing Efficacy
    • 1st Edition
    • Sadhna Aggarwal + 3 more
    • English
    The Microbiome and Cancer Treatment: Overcoming Resistance and Enhancing Efficacy delves into the intricate relationship between the microbiome and cancer treatment, highlighting the microbiome's critical role in drug resistance and therapeutic efficacy. The book's chapters are meticulously organized to provide a deep understanding of how the microbiome interacts with the immune system and influences cancer development and response to therapies. This book opens new avenues for investigation by providing a better understanding of the mechanisms of resistance and the role of microbiome alterations in chemoresistance.Sect... also address the complex "chicken-or-egg" relationship between microbiome alterations and chemoresistance. A diverse blend of chapters foster interdisciplinary collaboration across fields such as immunology, microbiology, oncology, and pharmacology, promoting holistic approaches to cancer treatment. Readers will benefit by gaining awareness and a better understanding of how the microbiome impacts health, particularly in the context of cancer, leading to more informed health choices.

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