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Books in Life sciences

Applied Biomechatronics Using Mathematical Models
1st Edition
Jorge Garza Ulloa
English
Applied Biomechatronics Using Mathematical Models provides an appropriate methodology to detect and measure diseases and injuries relating to human kinematics and kinetics. It features mathematical models that, when applied to engineering principles and techniques in the medical field, can be used in assistive devices that work with bodily signals. The use of data in the kinematics and kinetics analysis of the human body, including musculoskeletal kinetics and joints and their relationship to the central nervous system (CNS) is covered, helping users understand how the complex network of symbiotic systems in the skeletal and muscular system work together to allow movement controlled by the CNS. With the use of appropriate electronic sensors at specific areas connected to bio-instruments, we can obtain enough information to create a mathematical model for assistive devices by analyzing the kinematics and kinetics of the human body. The mathematical models developed in this book can provide more effective devices for use in aiding and improving the function of the body in relation to a variety of injuries and diseases.
Bipolar Disorder Vulnerability
Perspectives from Pediatric and High-Risk Populations
1st Edition
Jair Soares + 2 more
English
Bipolar Disorder Vulnerability: Perspectives from Pediatric and High-Risk Populations synthesizes our current understanding of high-risk and pediatric populations to aid readers in identifying markers of vulnerability for the development of bipolar disorder, with an ultimate goal of the development of drug targets and other therapies for early diagnosis and treatment. The book provides readers with an understanding of biological and environmental factors influencing disease manifestation that will aid them in defining discrete clinical stages and, importantly, establish an empirical basis for the application of novel therapeutics in a phase of illness during which specific treatments could more effectively alter disease course. Whereas most of the literature available on the pathophysiological mechanisms of bipolar disorder focuses on chronically ill adult individuals, this represents the only book that specifically examines pediatric and high-risk populations. An estimated 30 to 60 percent of adult bipolar disorder patients have their disease onset during childhood, with early-onset cases representing a particularly severe and genetically loaded form of the illness.
The Paracellular Channel
Biology, Physiology, and Disease
1st Edition
Jianghui Hou
English
The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization.
The Cerebellum: Disorders and Treatment
Handbook of Clinical Neurology Series
1st Edition
Volume 155
English
The Cerebellum: Disorders and Treatment, Volume 155 updates readers on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice, and (2) Therapy (including insights into innovative drug and rehabilitative approaches). The book's innovative structure discusses cerebellar disorders in children and adults as a continuum, with its companion volume, The Cerebellum: From Embryology to Diagnostic Investigations detailing embryology, anatomy, function and diagnostic investigations and neuroimaging, including conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies.
Bioinformatics Algorithms
Design and Implementation in Python
1st Edition
Miguel Rocha + 1 more
English
Bioinformatics Algorithms: Design and Implementation in Python provides a comprehensive book on many of the most important bioinformatics problems, putting forward the best algorithms and showing how to implement them. The book focuses on the use of the Python programming language and its algorithms, which is quickly becoming the most popular language in the bioinformatics field. Readers will find the tools they need to improve their knowledge and skills with regard to algorithm development and implementation, and will also uncover prototypes of bioinformatics applications that demonstrate the main principles underlying real world applications.
The Cerebellum: From Embryology to Diagnostic Investigations
Handbook of Clinical Neurology Series
1st Edition
Volume 154
English
The Cerebellum: From Embryology to Diagnostic Investigations, Volume 154 is designed to update the reader on the latest and clinically relevant advances in the study of cerebellar diseases in children and adults. It is organized into sections detailing: (1) Embryology, Anatomy and Function, and (2) Diagnostic investigations: Neuroimaging, and includes content on conventional sequences, diffusion tensor imaging, functional MRI, and connectivity studies. Its companion volume, The Cerebellum: Disorders and Treatment, describes disorders (starting from the fetal cerebellum, to adult cerebellum) encountered during daily practice and therapy (including insights into innovative drug and rehabilitative approaches to treat children and adults with cerebellar disorders).
Human Prion Diseases
1st Edition
Volume 153
English
Human Prion Diseases, Volume 153 is designed to update the reader on the latest advances and clinical aspects of prion diseases. The book is organized into five sections, including the pathophysiology of prions and a description of animal and human diseases. This is followed by detailed reports on recent advances in diagnosis strategies for the development of novel anti-prion molecules and possible designs of clinical trials in such a rare disease. An introductory chapter gives an extensive historical background of prion research, with a final chapter highlighting recent progress, and more importantly, unsolved problems.
The Physiology of Physical Training
1st Edition
Zsolt Radák
English
The Physiology of Physical Training provides complete coverage of the physiological and methodological aspects of physical training, providing essential knowledge for anyone involved in exercise physiology. Physiological processes at the cellular level (and for the whole organism) are covered to better explain particular training methods and convey a deeper knowledge and understanding of training techniques. Coverage of exercise training-induced adaptive responses and the most appropriate training methods to bring about targeted adaptive changes are also included. This is the perfect reference for researchers of physiology/kinesiolo... and human kinetics, practicing coaches, graduate students and sports medicine specialists.
Antimicrobial Peptides in Gastrointestinal Diseases
1st Edition
Chi Hin Cho
English
Antimicrobial peptides (AMPs), including cathelicidins and defensins are host defence peptides that carry out multiple roles in the gastrointestinal (GI) tract. Antimicrobial Peptides in Gastrointestinal Diseases presents knowledge about the physiological functions and pharmacological actions of AMPs in inflammation, cancer, and further infection of the GI tract. The book provides coverage from the basic research to clinical application for GI diseases. Current research and development of AMPs is presented, opening the way for further work on these peptides, not only in the context of GI diseases, but also for similar pathologies in other organs. AMPs are key to the regulation of human microbiome and second line defence in the GI mucosa, prevent colonization of pathogens and modulation of innate response to invading pathogens, and modify immunological reactions during inflammatory processes and oncogenic development in the GI mucosa. More importantly, AMPs possess diversified anti-microbial actions against various infectious diseases in the GI tract. With these physiological functions and pharmacological actions, AMPs have significant potential as therapeutic agents for the treatment of inflammation, cancer and further infection in the GI tract.
An Atlas of Comparative Vertebrate Histology
1st Edition
Donald B. McMillan + 1 more
English
Atlas of Comparative Vertebrate Histology looks at the histology of a wide range of vertebrates, representative of all the major classes and families, with examples ranging from amphioxus to primates. The authors focus their microscope on commonly seen vertebrates as well as ‘non-standard’ species, such as lamprey, hagfish, dogfish, skate, rock bass, cod, river catfish, toad, amphiuma, leopard and bull frog, garter and brown snake, Coturnix quail and cowbird. The study of comparative histology in the vertebrates helps students and researchers alike understand how various groups have addressed similar problems, opening doors to interesting research possibilities. Not all vertebrates follow the mammalian model of tissue and organ structure. When dealing with unique species, we see some structures taken beyond their ‘normal’ function. Comparative histology allows us to understand the structural responses underlying the physiology unique to each vertebrate group.

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