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Books in Life sciences

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  • Transcriptomics in Atherosclerosis

    Deciphering Molecular Signatures and Advancing Therapeutic Strategies
    • 1st Edition
    • Yvan Devaux + 1 more
    • English
    Transcriptomics in Atherosclerosis: Deciphering Molecular Signatures and Advancing Therapeutic Strategies explores how transcriptomic research is transforming our understanding and management of atherosclerosis. Bridging molecular biology and clinical medicine, it delves into the dynamic regulation of gene expression, the role of non-coding RNAs, and emerging insights from epitranscriptomics.T... book emphasizes advanced technologies such as single-cell and spatial transcriptomics, while embracing systems-level integration with other omic layers. It highlights how these approaches can reveal disease mechanisms, refine risk stratification, and guide the development of RNA-based diagnostics and therapies.Designed for researchers, clinicians, and translational scientists, this volume moves beyond generic overviews to present current methods, practical insights, and real-world challenges in the field. By doing so, it lays the groundwork for a new generation of precision strategies in cardiovascular care.

  • Marine Microbiome and Microbial Bioprospecting

    Diversity and Bioactive Potential
    • 1st Edition
    • Manikkam Radhakrishnan + 3 more
    • English
    Marine Microbiome and Microbial Bioprospecting: Diversity and Bioactive Potential comprehensively discusses the diversity of microbes present in various marine ecosystems, their bioprospecting potential, and how they can be utilized to derive bioproducts that benefit different fields and industries. Sections overview marine microbes, their ex situ conservation, and the tools and techniques used to study marine microbial diversity and taxonomy. In addition, it explores and details microorganisms in different marine ecosystems and considers how bioactive metabolites from diverse marine microorganisms can be harnessed to combat pathogens, used in industrial products and in environmental remediation and degradation, and enhanced for agricultural and aquaculture applications.With contributions from experts in the field, this book aims to be a valuable resource for researchers and industry professionals in microbiology and biotechnology and anyone involved in finding lead molecules from marine microbial resources for wide-ranging applications.

  • Immuno-oncology and Immunotherapy Part E

    • 1st Edition
    • Volume 199
    • English
    Immuno-oncology and immunotherapy, Part E, Volume 199 in the Methods in Cell Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including an Evaluation of agents that affect anti-tumor function of CD8+ T cells at activation, Cancer cyro-immunotherapy: Models and methods, Methods for analysis of cancer- and TLS-associated immune infiltrates by multiplex immunofluorescence histology, In-vivo measurement of the extracellular ATP concentration by bio-luminescent probes, and much more.Additional sections cover the Analysis of the tumor microenvironment using imaging mass cytometry data, Saphenous vein blood collection for different immune analyses of living mice, Use of mouse KO models to validate the specificity of monoclonal antibodies, Imaging mass cytometry to analyze the immune TME, Autoimmune arthritis: Transgenic mouse models and methods, Assessment of human and mouse tumor-antigen specific CD8+ T cells by multimer staining in multiple compartments, and more.

  • Advances in Food Security and Sustainability

    • 1st Edition
    • Volume 10
    • English
    Food Security and Sustainability: Global Challenges and Innovations, Volume 10 in the Advances in Food Security and Sustainability series highlights the latest developments in addressing food security concerns worldwide. This volume presents insightful chapters on crucial topics, including The Nexus of Food Security, Water Security, and Land Sustainability in Africa, Impact of Climate Disaster, Migration, and Health Risk on Food Security in Africa, Artificial Intelligence and Machine Learning in Food Safety: Challenges, Innovations, and Future Perspectives, and Food Security Amidst Disasters: Cases in the Philippines, among others.Additional chapters explore Sustainable Water Management for Food Security, Meat Consumption in Africa: Trends, Challenges, and Impact, Food Security and Global Water Security, The Role of Pharmacists in Addressing Nutritional Deficiencies in Food-Insecure Countries, and Biofortification: Addressing Micronutrient Deficiencies in Staple Foods in Africa. The volume also covers innovative solutions such as Advancing Women's Roles in Nutrition-Sensitive Agricultural Practices in Africa, Nurturing Nutrition-Sensitive Agriculture in Africa: Policy and Institutional Backing, and Planetary Health and Food Sustainability in Africa: Challenges, Opportunities, and Strategic Pathways.This comprehensive collection provides an in-depth understanding of food security through the lens of climate change, health systems, technological advancements, and policy frameworks, making it an essential resource for researchers, policymakers, and practitioners in the field.

  • Revolutionizing Digital Healthcare Through Artificial Intelligence and Automation

    Principles, Technologies, and Applications
    • 1st Edition
    • Alex Khang
    • English
    Revolutionizing Digital Healthcare Through Artificial Intelligence and Automation: Principles, Technologies, and Applications is a transformative exploration of how Artificial Intelligence (AI) and automation technologies are reshaping the healthcare landscape. In an era where precision, efficiency, and accessibility in medical services are paramount, this book delves into cutting-edge advancements in AI-powered diagnostics, wearable smart devices, and automated patient care systems. It stands as a beacon for innovators and healthcare professionals who aim to harness technology to streamline processes, improve patient outcomes, and create sustainable solutions in an ever-evolving industry.Beyond its focus on AI and automation, the book also examines the ethical implications and challenges of integrating technology into healthcare. It discusses strategies for implementing these technologies while ensuring patient privacy, maintaining human connection in care delivery, and navigating regulatory hurdles. With detailed case studies and forward-looking insights, the text provides a comprehensive roadmap for leveraging digital tools to shape the future of healthcare.

  • Emerging Strategies in Cancer Metabolism

    Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids
    • 1st Edition
    • Neeraj Mishra + 2 more
    • English
    Emerging Strategies in Cancer Metabolism: Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids offers a revolutionary investigation of the complicated relationships between cancer metabolism and three crucial factors: the gut microbiota, reactive oxygen species (ROS), and the dysregulation of the short chain fatty acid (SCF) complex. This book adopts a thorough and interdisciplinary approach to untangle the intricate interactions between these components, providing fresh perspectives that fundamentally alters the understanding of cancer biology and therapy. In 14 chapters.Emerging Strategies in Cancer Metabolism: Role of Gut Microbiota, Reactive Oxygen Species, and Short Chain Fatty Acids provides a thorough investigation of the metabolic changes that occur inside cancer cells, illuminating how these changes promote tumour survival and progression, from introduction to future aspects. Researchers in cancer research, and gut microbiology will find this an essential reference.

  • Innovative Targeting Strategies in Breast Cancer Therapy

    • 1st Edition
    • Pankaj Kumar Singh + 4 more
    • English
    Innovative Targeting Strategies in Breast Cancer Therapy is a comprehensive reference addressing the challenge of non-specific drug distribution in the body, along with severe toxicity and adverse effects, by offering insights into targeted breast cancer treatment. It further educates researchers on formulating and developing novel carriers with target-specific attributes (such as targeted liposomes, nanoparticles, micelles, and dendrimers), contributing to a more refined approach to breast cancer. This book's content is presented in 12 chapters. The first chapters introduces the reader to the different breast cancer therapies followed by indepth information on targeting . Recognizing the need for targeted drug delivery in breast cancer treatment, this book presents an encompassing compilation of advanced research and formulation strategies. By focusing on effectively targeting cancer cells, the book mitigates dose-related toxicity associated with cytotoxic drugs, providing a comprehensive resource for improved treatment approaches. Research in oncology, pharmacology, medical researchers, biomedical engineers and clinical professionals will find this an essential reference.

  • The Science of Pharmacology

    • 1st Edition
    • Jahangir Moini + 3 more
    • English
    The Science of Pharmacology offers a detailed and contemporary exploration of medications, delving into the scientific principles behind drug actions and their therapeutic applications. It is an essential resource for students in pharmacology and pharmaceutical sciences, providing foundational knowledge on a wide range of topics. The book addresses the effects of drugs on various bodily systems, such as the nervous, respiratory, and cardiovascular systems, and also covers their impact on mental health and behavior. Beyond the core topics, the book also discusses special subjects like herbal medications and drug interactions.It includes valuable teaching materials, including test banks and quizzes, and offers comprehensive insights into toxicological treatments, making it an invaluable tool for both learning and teaching in the field.

  • Sommeil et santé mentale

    Troubles du sommeil et des rythmes biologiques associés aux troubles psychiatriques
    • 1st Edition
    • Pierre-Alexis GEOFFROY
    • French
    Les monographies en Psychiatrie sont des ouvrages de référence sur les troubles psychiatriques et les grandes problématiques de la discipline. Ellespermettent aux praticiens d’approfondir et d’actualiser leurs connaissances, en exposant les données fondamentales actuelles et leurs applications dansla pratique clinique. Le sommeil, pilier essentiel de la santé mentale, reste encore trop souvent sous-estimé dans la pratique psychiatrique. Pourtant, ces troubles sont omniprésents et intimement liés à de nombreux troubles psychiatriques, qu’il s’agisse des troubles de l’humeur, anxieux, psychotiques, neurodéveloppementau... des addictions ou encore des troubles des conduites alimentaires. Le véritable enjeu réside aujourd’hui dans la compréhension fine des mécanismes physiologiques et neurobiologiques du sommeil, afin d’améliorer le diagnostic, la prise en charge et la prévention des troubles psychiatriques associés. Les récentes avancées enneurosciences, en génétique et en chronobiologie offrent des perspectives inédites : il devient crucial d’intégrer pleinement la dimension du sommeil au cœur de la psychiatrie moderne, pour proposer des soins plus précis et personnalisés.Premie... ouvrage de référence en langue française sur le sujet, il offre une exploration complète des liens entre le sommeil, les rythmes biologiques et la santé mentale, structurée en trois parties essentielles. La première partie pose les bases fondamentales et cliniques du sommeil et de ses troubles en psychiatrie, en abordant différents champs : l’histoire, la physiologie, la neurobiologie, la clinique, l’épidémiologie, la psychométrie, ainsi que l’organisation du systèmede soins. La seconde partie se concentre sur les altérations du sommeil associées aux différents troubles psychiatriques, allant de l’enfant au sujet âgé. Elle propose également une sémiologie clinique éclairée par les dernières données scientifiques et des recommandations d’experts, des stratégies de diagnostic et des outils innovants. Enfin, une troisième partie traitent des prises en charge de ces troubles du sommeil et des rythmes biologiques en psychiatrie, avec des approches thérapeutiques variées et détaillées, allant de la pharmacothérapie aux psychothérapies et aux chronothérapeutiques... ouvrage est un outil indispensable aux psychiatres, psychologues, médecins d’autres spécialités impliqués dans la médecine du sommeil, chercheurs, étudiants, ainsi qu’à tous ceux qui souhaitent approfondir leurs connaissances et leur pratique, dans ce domaine en pleine expansion. Cet ouvrage s’adresse à un large public professionnel. À la croisée de la psychiatrie, de la psychologie, de la physiologie, des neurosciences et de la médecine du sommeil, Sommeil et santé mentale a pour ambition d’offrir des repères solides et des outils pratiques pour mieux comprendre, diagnostiquer et traiter les troubles du sommeil en psychiatrie. POINTS CLÉSComprendre les mécanismes physiologiques, neurobiologiques et chronobiologiques du sommeil en lien avec la santé mentale.Repérer les troubles du sommeil associés aux principales pathologies psychiatriques et leur impact sur le diagnostic et la prise en charge.Proposer une stratégie thérapeutique adaptée au trouble et au patient.Pierre Alexis Geoffroy, est professeur des universités à l’université Paris Cité et praticien hospitalier au sein du département de psychiatrie et addictologie de l’hôpital Bichat-Claude Bernard et du 22e secteur du GHU Paris psychiatrie et neurosciences. Il est également chef de service ducentre de référence ChronoS (psychiatrie, chronobiologie et sommeil).

  • Secondary Metabolites in Stress and Disease Management

    A Natural Alternative
    • 1st Edition
    • Amrita Srivastava + 1 more
    • English
    Secondary Metabolites in Stress and Disease Management: A Natural Alternative details the sources and diversity of microbial and plant secondary metabolites, the methods used for their detection and extraction, their novel applications in disease management, and inclusion in mainstream therapy. Organized into three main sections, the book begins by discussing the potential of microbes, plants, microalgae, and cyanobacteria as valuable sources of secondary metabolites, their role and mechanisms of action in symbiotic and competitive interactions, extractions and purification strategies, and the means to maximize their production. The book goes on to explore the utility of secondary metabolites in mitigating plant stress and their therapeutic impact on human health management. With contributions from experts in the field, Secondary Metabolites in Stress and Disease Management is a useful interdisciplinary resource for researchers, professors, graduate and postgraduate students, and industry professionals studying applied microbiology, biotechnology, biochemistry, pharmacology, and plant science.

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