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Books in Life sciences

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    • Oral Delivery of Insulin

      • 2nd Edition
      • T.A. Sonia + 1 more
      • English
      Oral delivery of Insulin, Second Edition is a complete reference on non-invasive insulin delivery systems, focusing on the prospect of oral delivery of peptides. The chapters in the revised edition present a comprehensive evaluation of the insulin therapy approaches, with an emphasis on insulin delivery strategies and current advances in engineered insulin delivery systems such as nano/microcarriers and hydrogels. Chapters provides an overview of diabetes mellitus, cover technological innovations, explore artificial intelligence and machine learning approaches to manage diabetes, explore a wide range of non-invasive and alternative routes of insulin administration, and much more.Other chapters cover challenges and strategies in oral insulin delivery, the experimental techniques used to develop oral insulin carriers, the use of polymeric nano and microparticles for insulin delivery, and the use of lipids and inorganic nanoparticles in insulin delivery. The final chapter provide an overview of current clinical trials on insulin delivery and future perspectives in the area. Clinicians can benefit from this information to develop a clear understanding about the research carried out worldwide in the field of oral delivery of insulin, including those in the clinical phase.

    • From DNA to Traditional Chinese Medicine

      • 1st Edition
      • Jesse Li-Ling
      • English
      From DNA to Traditional Chinese Medicine presents how genetic disorders can be explained using concepts of Traditional Chinese Medicine. This book explores the striking correlation between the characteristics of congenital syndromes and fundamental concepts of Traditional Chinese Medicine, such as Jing-Mai (Meridians or Channels) and Zang-Fu (the Yin and Yang internal organs). This correlation appears to be systematic and comprehensive, suggesting that these Chinese concepts have correctly summarized the connections between particular parts of the human body during embryonic development. Should this discovery be correct, it will have an immense impact on the understanding of genomic medicine as well as Chinese medicine. The uncovering of the mechanism of Chinese medicine, may also lead to development of new treatments for various human diseases. This book covers topics including genetic syndromes and fundamental concepts of Traditional Chinese Medicine. Starting with DiGeorge/Velocardiof... syndrome, this book will first introduce the basics of Medical Genetics and congenital syndromes, and then the fundamental concepts of Traditional Chinese Medicine including Jing-Mai and Zang-Fu. It will provide a completely new perspective on genetic syndromes with insights into how they relate to Traditional Chinese Medicine. This book is a valuable resource for graduates, medical undergraduates and researchers as well as professionals from both academia and industry.

    • Soil Microorganisms for Plant Growth Promotion and Soil Health

      • 1st Edition
      • Gustavo Santoyo
      • English
      Soil Microorganisms for Plant Growth Promotion and Soil Health provides readers with an overview of plant growth-promoting microorganisms and their molecular mechanisms to improve plant growth and soil health. Students and researchers in soil science will gain a comprehensive understanding of soil microbiota diversity and functions, along with insights into the mechanisms by which plant growth, including molecular processes involved in nutrient acquisitions and defense mechanisms work. In addition, the book provides a noteworthy emphasis on fungi.A soil beneficial microbe cannot only be the living cells, but also their components, such as molecules or enzymes produced by this beneficial microbiota. Molecules like microbial phytohormones can be excellent promoters or regulators of plant growth, as well as proteins and other compounds like volatiles, which might elicit a systemic resistance response against pathogenic threats. Therefore, plant growth promoters living in soil, associated with plant roots, could act through direct beneficial interactions with the plant, by stimulating or regulating growth responses to environmental conditions, or indirectly by inhibiting the growth of potential microbial pathogens and herbivore pests.

    • Lipases

      Foundations, Applications, and Perspectives
      • 1st Edition
      • Eliane Pereira Cipolatti + 2 more
      • English
      Lipases: Foundations, Applications, and Perspectives, a new volume in the Foundations and Frontiers of Enzymology series, offers a practical, in-depth discussion of lipases and instruction in their use across research and industry. Here, global experts in the field introduce readers to basic lipase biology and the history of the field, interfacial activation and lipase lids, evolving analytical techniques and technology for studying lipases, and a range of lipase applications, from health and drug discovery to biofuels, food, cosmetics, and waste treatment. Lipase sources and production methods discussed include mammalian lipases, microbial lipase production, biomass lipase production, immobilized lipases, and tailor-made recombinant lipases, among other approaches.

    • Nervonic Acid and Brain Health

      • 1st Edition
      • Xianyang Chen + 2 more
      • English
      Nervonic Acid and Brain Health is a comprehensive guide for professionals and researchers seeking in-depth knowledge about nervonic acid. This book meticulously delves into its functions, sources, synthesis, and therapeutic applications. Readers will find valuable information on the connections between nervonic acid, brain health, and neurological conditions, presenting data that is currently scarce in other publications. The book emphasizes evidence-based research findings, making it an essential resource for understanding the impact of nervonic acid on cognitive development and its potential therapeutic benefits.In addition to exploring nervonic acid's role in brain health, the book addresses its significance in infant and toddler brain development, the consequences of deficiency during pregnancy, and its inclusion in infant formula and cognitive health products. The association with neurological conditions such as Alzheimer's disease, multiple sclerosis, and cerebral ischemia is thoroughly examined, providing practical insights for medical professionals and caregivers. This text bridges the gap between scientific research and consumer interests, offering real-world relevance and application.

    • Future of Internet of Bio-Nano Things in Personalized Healthcare

      Applications and Challenges
      • 1st Edition
      • Jayachitra Sekar + 3 more
      • English
      Future of Internet of Bio-nano Things in Personalized Healthcare: Applications and Challenges explores the core principles of nanomaterials and the sensing paradigms essential for medical devices based on nano-sensors technology, examining the latest theoretical and practical developments in Internet of Bio-nano Things (IoBNT) for health applications. This book explores how IoBNT facilitates the detection and treatment of diseases within the human body through communication between an in-body network of nanodevices and an external control unit. Readers will discover the transformative benefits of IoBNT, which integrates information and communication technologies with medical and nano-bio sensor devices to enhance patient care. The book highlights advances in telemedicine, including highly functional electronic medical devices like implantable and wearable devices engineered through nanotechnology. It details real-time case studies on smart drug delivery, edge computing, and personalized healthcare applications to provide valuable insights into optimizing network performance and utilization in personalized healthcare. The comprehensive exploration of machine learning algorithms and communication protocols further equips readers with the knowledge to design and implement end-to-end IoBNT solutions.

    • Nitrogen Heterocycles in Cancer Therapy

      • 1st Edition
      • Sanjeev Kumar Sahu + 1 more
      • English
      Nitrogen Heterocycles in Cancer Therapy offers an in-depth exploration of the latest nitrogen-containing heterocyclic compounds used in the fight against cancer. Across ten chapters, the book lays a solid foundation in oncology while delving into the design, synthesis, and anticancer mechanisms of these compounds. Drawing from current research, it examines how these molecules are engineered to target cancer cells, and highlights both in-vitro and in-vivo evaluation techniques. Through clear explanations and detailed analysis, the book provides readers with a comprehensive understanding of molecular strategies and promising new agents shaping modern cancer therapy.In addition to covering the science behind these compounds, the book presents clinical study reports demonstrating their effectiveness across various cancer types. It also discusses the global market impact, pharmacoeconomics, and future directions for drug development. By integrating the latest advancements and practical insights, this work stands out as an invaluable resource for researchers, clinicians, and students seeking to stay at the forefront of innovative cancer treatments.

    • Isothermal Titration Calorimetry in Enzymology

      Techniques and Applications
      • 1st Edition
      • Anthony Mittermaier + 1 more
      • English
      Isothermal Titration Calorimetry in Enzymology: Techniques and Applications provides a thorough, practical overview of ITC as a productive and powerful tool for quantifying enzyme catalysis and interactions with substrates, products, cofactors, and inhibitors. Here, global experts in the methodology discuss the full capabilities of ITC and how it may be applied in research, medicine, and industry and offer a basis to continue leveraging ITC as its uses expand and evolve. This book bridges the gap between research and application by giving extensive technical details on cutting edge ITC techniques across a wide swath of both ITC kinetics measurements and ITC thermodynamic measurements, alongside case studies illustrating the depth of knowledge that can be obtained. Applications discussed include measuring binding kinetics by ITC, analyzing ITC kinetic data, in vivo enzyme kinetics by ITC, analyzing enzyme kinetics in crowded solutions, studying catalysis of biological substrates, interpreting ITC binding curves, ITC in drug discovery, ITC in the development of cancer therapeutics, ITC analysis of aminoglycoside resistance enzymes, studying enzyme interactions with toxic metals, using ITC to study ubiquitination, and ITC studies of glycoside hydrolases, among others.

    • Maternal-Fetal and Neonatal Endocrinology

      Physiology, Pathophysiology, and Clinical Management
      • 2nd Edition
      • Christopher S. Kovács + 1 more
      • English
      Maternal-Fetal and Neonatal Endocrinology: Physiology, Pathophysiology, and Clinical Management, Second Edition continues to systematically examine the normal and abnormal endocrinology of the pregnant and lactating female and of the fetus and neonate. This new edition expands coverage of specific disorders and diseases beyond the current endocrinology content on the market making it the go-to reference for translational and clinical research scientists to appreciate the research gaps that require further investigation. It’s comprehensive coverage of pathophysiology, diagnosis, and treatments, will help readers better understand how various diseases present differently in pregnancy and lactation and how to respond to related complications.

    • Polyamines-Phytohormones-Nutrients Network

      Nexus in Plant Responses to Abiotic Stresses
      • 1st Edition
      • Asim Masood + 3 more
      • English
      Polyamine-Phytohormo... Network: Nexus in Plant Responses to Abiotic Stresses presents the latest global research on key tools for improving physiological and biochemical mechanisms that enhance plant health and productivity.Exposur... of plants to abiotic stresses is inevitable, often leading to impaired growth, metabolism, and productivity. However, plants are naturally equipped with endogenous chemicals including intracellular messengers and signalling molecules that counteract potential stress impacts, protect cellular functions, and promote healthy growth and production. Polyamines (PAs) are low-molecular-weight... nitrogen-containing compounds with aliphatic polycationic properties. Beyond their role in growth and development, PAs enhance plant tolerance to abiotic stresses. Given their connection with phytohormones and mineral nutrients, understanding their interactions—whether synergistic or antagonistic—could shed light on their potential to mitigate these stresses.Written by a team of expert contributors, this volume in the Plant Biology, Sustainability, and Climate Change series focuses on the interactions among PAs, phytohormones, and mineral nutrients that are crucial for regulating nutrient assimilation, carbon fixation, and secondary metabolic pathways.

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