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Books in Life sciences

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    • Heart Failure in the Child and Young Adult

      From Bench to Bedside
      • 2nd Edition
      • Joseph Rossano + 5 more
      • English
      Heart Failure in the Child and Young Adult: From Bench to Bedside, Second Edition highlights unique aspects of heart failure in the young. This comprehensive resource combines research from multiple contributors with current guidelines to bridge the knowledge gap for the recognition and management of heart failure in children. Coverage begins with the basic science of heart failure and then progresses through diagnosis, management, treatment, and surgery, finally concluding with advanced special topics, including genetics, self-management, and nanomedicine.This new edition covers advancements in the field, including additional chapters and discussion on biomarkers, neuromuscular disease, quality of life, palliative care, and the impact of COVID-19 in myocarditis and multisystem inflammatory syndrome in children. It will serve as an indispensable reference to basic science researchers in cardiology, pediatrics, cardiologists, and pediatric cardiologists.

    • Machine Learning in Drug Development: Part 1

      • 1st Edition
      • Volume 64
      • English
      Machine Learning in Drug Development: Part One, Volume 64 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field. Chapters in this release include Artificial Intelligence in Small Molecule and Nucleic Acid Research: A Review, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, AI-aided Drug Development for Protein Degraders: Biology Validation, Disease-association, Drug Repurposing, Transforming Modern Drug Discovery with Machine Learning, Artificial Intelligence in the Development of Antiviral Drugs: Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery.

    • Myasthenia Gravis, Part B

      • 1st Edition
      • Volume 183
      • English
      Myasthenia Gravis, Part B, Volume 183 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Typical and Atypical Clinical Presentations, Diagnosis and Differential Diagnosis, Clinical Evaluation, Myasthenia Gravis in Women, Fatigue and Myasthenia Gravis, Clinical and Electrophysiologic Outcomes, Standard Treatment and Different Geographical Approaches, Rescue Treatments, Novel Treatments for Myasthenia Gravis, Measuring Treatment-Related Side Effect Burden in Myasthenia Gravis, Exercise and Myasthenia Gravis, The Social and Personal Impact of Myasthenia Gravis, and Future Perspectives.

    • Interaction of Food Macromolecules

      The Matrix of Future Foods
      • 1st Edition
      • Ibrahim Khalifa + 2 more
      • English
      Interaction of Food Macromolecules: The Matrix of Future Foods provides a detailed understanding on why biological macromolecules, i.e., proteins, lipids, and carbohydrates with ligands interactions are essential to understanding biology at the molecular level. The book aims to create a multidisciplinary forum of discussion on the interaction between macromolecules and ligands, providing an understanding on how biological macromolecules with ligands interactions are central to facilitating the discovery, design, and development of future, functional foods. In addition, it outlines information available on the macromolecules-ligan... interaction that happens inside the food matrixes and inside our bodies.Knowing about the mechanisms responsible for the macromolecules-ligan... recognition and binding facilitates the discovery, design, and development of future and functional foods.

    • Emerging Technologies in the Healthcare System for Sustainable Development

      • 1st Edition
      • Kamil Reza Khondakar + 1 more
      • English
      Emerging Technologies in the Healthcare System for Sustainable Development explores the forefront of modern healthcare by shedding light on cutting-edge technologies such as artificial intelligence and their profound implications. The book places a distinct emphasis on sustainability, an increasingly pivotal point of discussion in public discourse. Centered around sustainability, the book adeptly underscores the significance and immediacy of incorporating emerging technologies into the healthcare landscape to effectively tackle the complexities of contemporary healthcare systems. Comprising 12 comprehensive chapters, Emerging Technologies in the Healthcare System for Sustainable Development distinguishes itself by its holistic approach, unwavering commitment to sustainability, relevance for interdisciplinary healthcare professionals, accessibility to non-technical readers, integration of research within real-world case studies, and its forward-thinking perspective. This book stands as an invaluable asset for healthcare professionals, researchers, scientists, practitioners, students, and anyone keen on expanding their knowledge within related domains.

    • Ophthalmic Drug Delivery

      Advancement, Industrialization Prospect and Applications
      • 1st Edition
      • Neelesh Kumar Mehra
      • English
      Ophthalmic Drug Delivery: Advancement, Industrialization Prospect and Applications delves into the complexities and potential of scaling up and commercializing pharmaceutical innovations within ophthalmology. This book serves as a complete guide through research findings, industry insights, and regulatory guidelines, offering a thorough roadmap for the future of drug delivery systems targeting the eye. The importance of understanding the eye's physiology and anatomy is emphasized, laying the foundational knowledge necessary for developing effective treatments. The book continues by exploring various aspects such as novel formulations, fixed-dose combinations, and microbiological considerations.It also discusses cutting-edge research in reverse engineering approaches, the significance of Quality by Design (QbD), and the treatment of eye-related diseases like glaucoma, age-related macular degeneration, uveal melanoma, cataracts, and fungal keratitis. Corporate researchers will find the manufacturing insights particularly beneficial, making this an essential resource for professionals in the field of ophthalmic drug delivery.

    • Nanomaterials in the Soil-Plant Continuum

      • 1st Edition
      • Manoj Shrivastava + 1 more
      • English
      Nanomaterials in the Plant-Soil Continuum explores the various nanomaterials that are impacting agriculture whether through intentional or unintentional pathways. Providing a concise outlook of NMs in soil chemistry, physics, and biology, it highlights nanomaterial transformation in soil and subsequent plant uptake. Plants may be exposed to naturally generated or artificially produced nanomaterials (ENMs). They can absorb NMs from the soil through roots or leaves but return them to the soil through litter, creating an intricate network of NMs cycling in a soil-plant continuum. Understanding this NM transformation in soil and subsequent plant uptake is integral to understanding, and protecting, an ecosystem. Nanomaterials in the Plant-Soil Continuum also discusses the translocation and biotransformation of NMs in plants and their effects on plant metabolism. Considering NMs as new and emerging agrochemicals, a detailed understanding of their role in the soil-plant continuum, ecosystem functioning, and services will also be discussed. This volume in the "Nanomaterial Plant Interactions" series highlights the recent insights into the impact, fate, and transport of NMs in the soil-plant continuum and their potential impacts on soil and plant health.

    • Biomarkers in Kidney Transplantation

      Clinical Aspects and Laboratory Determinations
      • 1st Edition
      • Dr Smita Pattanaik + 1 more
      • English
      Biomarkers in Kidney Transplantation: Clinical Aspects and Laboratory Determination provides a focused study on traditional and emerging biomarkers to predict early rejection of kidney transplants supporting appropriate therapeutic interventions. Coverage includes predictive and diagnostic biomarkers for different types of rejections, including biomarkers of acute, chronic/sub chronic rejection or clinical rejection, T-cell mediated rejection, antibody mediated rejection and mixed rejection. Comparisons are provided for broad classification of pharmacokinetic versus pharmacodynamic biomarkers, and differentiation is shown between the susceptibility, diagnostic, predictive, prognostic and monitoring biomarkers.Coverage of the analytical aspects of biomarker measurement, the process of biomarker discovery and their clinical validation addresses both the clinical features of biomarkers as well as the pitfalls of determining such biomarkers in clinical laboratories. By combining all current markers known for kidney transplant in one collection, this easy-to-use reference is perfect for pathologists, clinical pharmacologists, clinical laboratory scientists and all physicians involved in organ transplantation, including immunologists and transplant surgeons.

    • Harnessing Quorum Quenching for Disease Management

      • 1st Edition
      • Arpita Roy + 2 more
      • English
      Harnessing Quorum Quenching for Disease Management explores the process of quorum quenching in disrupting bacterial cell communication and how this mechanism can be utilized in the medical field. This book provides a detailed overview of quorum quenching and quorum sensing, delving into the key aspects of this process including the enzymatic mechanisms and methods available to study these. It covers quorum quenching applications, including the regulation of virulence factors, antimicrobial resistance and disease treatment, and the use of quorum quenching bacteria for medical intervention. It also considers genetically modified organisms to produce quorum quenching enzymes, nanomaterials for optimizing quorum quenching, in silico technology and the impact of synthetic biology, closing with a discussion of the current limitations and future prospects for this field. This book is an ideal reference for researchers and advanced students with an interest in quorum quenching and quorum sensing working across a range of fields, including microbiology, cell biology, biomedicine, biochemistry, biotechnology and related areas.

    • Bladder Cancer Breakthroughs

      A Global Perspective on Diagnosis, Treatment, and Patient Care
      • 1st Edition
      • Bhupendra G. Prajapati + 2 more
      • English
      Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is a groundbreaking scientific resource that delves into the latest advancements in the diagnosis and treatment of bladder cancer, a prevalent malignancy affecting hundreds of thousands worldwide. This meticulously curated volume brings together contributions from leading scientists and healthcare professionals from around the globe, providing a comprehensive overview of contemporary understanding and innovative strategies in managing this complex disease. Bladder Cancer Breakthroughs: A Global Perspective on Diagnosis, Treatment, and Patient Care is not merely a collection of research findings; it is a vital resource that fosters a holistic perspective on patient-centered care. By synthesizing clinical expertise and evidence-based practices, this book aims to empower healthcare providers with the knowledge and tools needed to improve outcomes for individuals living with bladder cancer, ultimately contributing to the global fight against this challenging disease. This book serves as an essential guide for healthcare providers, including physicians, oncologists, immunologists, pharmacists, and physical therapists, striving to enhance patient care and treatment outcomes

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