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Elsevier

Books in Life sciences

  • Disease Pathways

    An Atlas of Human Disease Signaling Pathways
    • 1st Edition
    • Anastasia P. Nesterova + 7 more
    • English
    Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease.

  • Kalanchoe (Crassulaceae) in Southern Africa

    Classification, Biology, and Cultivation
    • 1st Edition
    • Gideon F. Smith + 2 more
    • English
    Kalanchoe (Crassulaceae) in Southern Africa: Classification, Biology, and Cultivation provides a highly readable, illustrated account of the Kalanchoe species. The book includes an overview of the family Crassulaceae and genus Kalanchoe in global and subcontinental contexts that is followed by information on the taxonomic history of the genus. The characters and ecology of the species are also discussed, including their distribution ranges, where they occur, their habitat preferences, and where the species were formally recorded for the first time. For each indigenous and naturalized species, comprehensive taxonomic, descriptive and other information of interest is provided. This is the must-have resource for plant scientists, plant taxonomists, ethnobotanists, herbarium curators, ecologists, pharmacologists, invasions scientists, horticulturalists and landscape designers.

  • Mucosal Vaccines

    Innovation for Preventing Infectious Diseases
    • 1st Edition
    • David W. Pascual
    • English
    Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced and discussed in an easy-to-understand format.

  • Methods of Therapeutic Drug Monitoring Including Pharmacogenetics

    • 2nd Edition
    • Volume 7
    • Georg Hempel
    • English
    Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs.

  • Molecular Nutrition: Carbohydrates

    • 1st Edition
    • Vinood B. Patel
    • English
    Molecular Nutrition: Carbohydrates presents the nutritional and molecular aspects of carbohydrates. As part of the Molecular Nutrition includes sections covering carbohydrate metabolism, carbohydrates in the diet, insulin resistance, dietary sugars, cardiometabolic risk, lipoproteins, low-carbohydrate diets, antioxidants, refined dietary sugars, fats, glucose transporters, glucose sensing, the role of phosphorylation, carbohydrate responsive binding protein, cyclic AMP, peroxisome proliferator-activat... receptors, SIRT1, insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes rRNA and transcription, and more. In addition, the book addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health.

  • Neuroprotection in Autism, Schizophrenia and Alzheimer's disease

    • 1st Edition
    • Illana Gozes + 1 more
    • English
    Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry. Sections discuss the shared pathophysiological mechanisms that underlie autism, schizophrenia/mood disorders and Alzheimer’s disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders.

  • Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine

    Volume 1
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine, the first volume in the Integrative Cardiovascular Chinese Medicine series, provides a comprehensive guide to improving outcomes with cardiovascular medicine therapy options. Coverage includes the three types of medicines used in disease stage treatment, Chinese medicine, nutritional supplements and pharmaceutical drugs. All sections are organized according to drug class in western medicine and chapters in each section are organized according to disease stage, providing ease in navigation and reference within the book. This important reference will aid cardiovascular researchers in the study of integrative Chinese and western medicine as well as provide a clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.

  • The Autoimmune Diseases

    • 6th Edition
    • M. Eric Gershwin + 1 more
    • English
    The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.

  • DNA Repair

    • 1st Edition
    • Volume 45
    • English
    DNA Repair, Volume 45 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair, Translesion polymerases, mechanism and function, The Rev1-Polζ Mutasome: Structure and Interactions in Translesion Synthesis, Challenges for base excision repair enzymes: acquiring access to damaged DNA in chromatin Nucleotide excision repair, DNA damage recognition mechanisms in mammalian nucleotide excision repair, Advances in understanding DNA mismatch repair, and more.

  • Personalized Psychiatry

    • 1st Edition
    • Bernhard Baune
    • English
    Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders.

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