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Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of… Read more
SUSTAINABLE DEVELOPMENT
Save up to 30% on top Physical Sciences & Engineering titles!
Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple.
Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine.
This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease.
1. Part One (A.Nesterova, E.Klimov)1.1. Introduction to the cell signaling biochemistry and proteomics1.2. System biology and signaling pathways1.3. Complexity of molecular mechanisms of human diseases
2. Part Two (the chapter will contain numerous images with disease pathways)2.1. Cardiovascular Diseases2.1.1. Arrhythmogenic Right Ventricular Dysplasia (A.Nesterova)2.1.2. Atherosclerosis (V.Sobolev)2.1.3. Hypertension (S.Sozin)2.2. Dermatological Diseases2.2.1. Acne Vulgaris (A.Nesterova)2.2.2. Atopic Dermatitis (V.Sobolev, A.Nesterova)2.2.3. Ichthyosis (V.Sobolev, A.Nesterova)2.3. Endocrine and Metabolic Diseases2.3.1. Diabetes Mellitus Type 1 (A.Nesterova)2.3.2. Diabetes Mellitus Type 2 (A.Nesterova, M.Zharkova)2.3.3. Phenylketonuria (A.Nesterova)2.4. Intestinal Diseases2.4.1. Crohn's Disease (A.Nesterova, V. Sobolev)2.4.2. Ulcerative Colitis (V.Sobolev)2.4.3. Celiac Disease (V.Sobolev, A.Nesterova)2.4. Hepatology/Liver Diseases2.4.1. Alpha 1-Antitrypsin Deficiency (S.Sozin)2.4.2. Non-Alcoholic Fatty Liver Disease (M.Zharkova)2.5. Musculoskeletal System Diseases2.5.1. Osteoarthritis (S.Sozin, A.Nesterova)2.5.2. Osteopetrosis (S.Sozin)2.5.3. Osteoporosis (S. Sozin, A.Nesterova)2.6. Neurological Diseases2.6.1. Alzheimer's Disease (A.Nesterova)2.6.2. Migraine, Familial Hemiplegic (E.Klimov)2.6.3. Sclerosis (S.Sozin)2.7. Obstetrics and Gynecology Diseases2.7.1. Polycystic Ovary Syndrome (M.Zharkova)2.8. Ophthalmology/Eye Diseases2.8.1. Age-Related Macular Degeneration (S.Sozin)2.8.2. Cataract (A.Nesterova)2.8.3. Glaucoma (S.Sozin)2.9. Otolaryngological Diseases2.9.1. Hearing Loss (S.Sozin)2.9.2. Otitis Media (S.Sozin)2.10. Respirator and Pulmonology Diseases2.10.1. Asthma (A.Nesterova)2.10.2. Chronic Obstructive Pulmonary Disease (S.Sozin, A.Nesterova)2.10.3. Cystic Fibrosis (A.Nesterova)2.11. Nephrology Diseases2.11.1. Cystic Kidney Disease (M.Zharkova)
3. Part Three3.1. Methods of using intracellular maps for diagnosis of diseases in personalized medicine (A.Nesterova)3.2. Conclusion (A.Nesterova)
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