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Elsevier

Books in Life sciences

  • Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

    Volume 1
    • 1st Edition
    • Giuseppe Orlando + 4 more
    • English
    Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine.

  • Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

    Volume 2
    • 1st Edition
    • Giuseppe Orlando + 4 more
    • English
    Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation... also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine.

  • Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy

    • 1st Edition
    • Volume 7
    • English
    Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance.

  • Underexplored Medicinal Plants from Sub-Saharan Africa

    Plants with Therapeutic Potential for Human Health
    • 1st Edition
    • Namrita Lall
    • English
    Underexplored Medicinal Plants from Sub-Saharan Africa: Plants with Therapeutic Potential for Human Health examines a comprehensive selection of rarely explored plants that have been underestimated for their therapeutic value. The book contains monographs of medicinal plants, outlining their botanical description, geographical distribution, ethnobotanical usage, chemical constituents, sample and standard preparations and methods, and pharmacological properties. With expert contributors from South Africa, Mauritius, Seychelles, Cameroon and Nigeria, and the compilation of ethnobotanical, taxonomic and pharmacologic information for each species, this book is a valuable resource for researchers, academics in pharmacology, ethnopharmacology, medicinal plant sciences, and more.

  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 41
    • Sidhartha D. Ray
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 41, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered in this new release include Central Nervous System Stimulants and Drugs that Suppress Appetite, Antidepressants, Lithium, Drugs of Abuse, Hypnotics and Sedatives, Antipsychotic Drugs, Antiepileptics, Opioid Analgesics and Narcotic Antagonists, Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout, and much more.

  • Oxidative Stress

    Eustress and Distress
    • 1st Edition
    • Helmut Sies
    • English
    Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections: A conceptual framework for studying oxidative stress. Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress). The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution. Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer. Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science.

  • Evolution of the Human Brain: From Matter to Mind

    • 1st Edition
    • Volume 250
    • English
    Evolution of the Human Brain: From Matter to Mind, Volume 250 in the Progress in Brain Research, series documents the latest developments and insights about the origin and evolution of the human brain and mind. Specific sections in this new release include Evolution and development of the human cerebral cortex, Functional connectivity of the human cerebral cortex, Lateralization of the human cerebral cortex, Life history strategies and the human cerebral cortex, Evolution of the modern human brain, On the nature and evolution of the human mind, Origin and evolution of human cognition, Origin and evolution of human consciousness, and more.

  • Data for Nurses

    Understanding and Using Data to Optimize Care Delivery in Hospitals and Health Systems
    • 1st Edition
    • Molly McNett
    • English
    Data for Nurses: Understanding and Using Data to Optimize Care Delivery in Hospitals and Health Systems provides information for nurses on how to work with data to effectively evaluate and improve care delivery for patients. Quality, benchmarking, and research data are increasingly used to guide care in hospitals and health systems, and nurses are expected to actively use this information to identify interventions to optimize outcomes and meet reporting and financial targets. However, not all nurses receive formal training on data utilization, making interpretation and application of the different types of data difficult. This book provides information on topics such as benchmarking and reportable indicators, financial metrics, quality improvement, research, and implementation science, with applications to nursing practice. Important information on protective measures to guarantee integrity and security of personal patient data is also included. The book is a valuable resource for nurses and other healthcare professionals who require a basic understanding of key principles of data utilization in order to increase engagement in evidence-based practices, quality improvement, and mandatory reporting of key indices.

  • Molecular Biology of Neurodegenerative Diseases: Visions for the Future

    • 1st Edition
    • Volume 168
    • English
    Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Volume 168 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, Propagation and removal of cerebral amyloid angiopathy, and much more.

  • Biomimetic Nanoengineered Materials for Advanced Drug Delivery

    • 1st Edition
    • Afeesh Rajan Unnithan + 3 more
    • English
    Biomimetic Nanoengineered Materials for Advanced Drug Delivery is an indispensable guide for new developments in biomimetic nanoengineering for advanced drug delivery applications. Focusing on the fundamentals of a new type of nanocarriers for drug delivery in the most recent miRNA therapeutics, the book provides readers with detailed knowledge from the basics, to the most recent innovations. Early chapters of the book discuss a range of drug delivery techniques, including nanofibers, biomimetic polymers, 3D bioprinting, nanotechnology and radiofrequency sensitive nanocarriers. Later chapters explore miRNA therapeutics, magnetic nanoparticles, nanogel-based and ROS-mediated drug delivery systems. The book is a vital reference for biomaterials and nanomedicine researchers and clinicians with an interest in advanced drug delivery.

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