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Books in Life sciences

  • Pan-genomics: Applications, Challenges, and Future Prospects

    • 1st Edition
    • March 6, 2020
    • Debmalya Barh + 3 more
    • English
    Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics,” thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.

  • Dietary Sugar, Salt and Fat in Human Health

    • 1st Edition
    • March 6, 2020
    • Harry G. Preuss + 1 more
    • English
    Divided into four main sections, Dietary Sugar, Salt and Fat in Human Health explores the biochemical, pharmacological and medicinal aspects related to the overindulgence of dietary salt, sugar, and fat, along with possible remedies. Beginning with a general overview, the text outlines aspects associated with advancing age and human physiology, such as different aspects of insulin resistance, the advancing age phenomenon, central fat accumulation and metabolic perturbations and the role of the modern Western diet and the influence of dietary sugar, salt, and fat, with particular focus on their relation to multiple biochemical pathophysiological pathways. The second section of the book focuses on the roles of dietary sugars and their correlation with the chronic disease epidemic, with an emphasis on carbohydrate metabolism and its biochemistry, GI absorption, the glycemic index and the influence of fructose. The historical background of dietary sugars is discussed alongside Atkin’s hypothesis, and an overview of the correlation between dietary fibre and the glycemic index, including a chapter on sugar addiction. Section three contains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspects, including salt-sensitive hypertension, contribution of two steroid receptor pathways, vascular NO, intrarenal RAAS system and angiotensin. The fourth section highlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases, and further explores NAFLD and gender specific problems. Chapters in this section also investigate the benefits of the Mediterranean diet as well as myths related to cholesterol. Collected and carefully organized for researchers in nutrition, physiology, epidemiology, or sensory science, this book will also benefit general practitioners, surgeons, nurses, health professionals and practitioners, and students studying the role of diet in cardiometabolic disorders and disease.

  • Quaternary Ecology, Evolution, and Biogeography

    • 1st Edition
    • March 5, 2020
    • Valentí Rull
    • English
    Quaternary Ecology, Evolution, and Biogeography offers an introduction to the study of the ecological and evolutionary processes that have shaped our present biosphere under the influence of glacial-interglacial cycles. Written by an ecologist with paleoecological expertise, this book reviews the climactic changes that have occurred during the last 2.6 million years, along with the responses of organisms and ecosystems. It offers an understanding of the evolutionary origin of extant biodiversity, its biogeographical patterns, and the composition of modern ecological communities. In addition, it explores human evolution and the influence of our activities on the biosphere, especially in the last millennia.This book offers the latest information on how studying the past can contribute to our understanding of present climate issues for a better future, and is an ideal resource for researchers and students in the natural sciences.

  • Microbial Endophytes

    Functional Biology and Applications
    • 1st Edition
    • March 5, 2020
    • Ajay Kumar + 1 more
    • English
    Microbial Endophytes: Functional Biology and Applications focuses on endophytic bacteria and fungi, including information on foundational endophytes and the latest advances in relevant genomics, proteomics and nanotechnological aspects. The book provides insights into the molecular aspects of plant endophytes and their interactions and applications, also exploring the potential commercialization of endophytic microorganisms and their use as bio fertilizers, in biocontrol, and as bioactive compounds for other sustainable applications. Coverage of important and emerging legal considerations relevant to those working to implement these important bacteria in production processes is also included.

  • Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly

    • 1st Edition
    • Volume 170
    • March 4, 2020
    • English
    Computational Approaches for Understanding Dynamical Systems: Protein Folding and Assembly, Volume 170 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Pairwise-Additive and Polarizable Atomistic Force Fields for Molecular Dynamics Simulations of Proteins, Scale-consistent approach to the derivation of coarse-grained force fields for simulating structure, dynamics, and thermodynamics of biopolymers, Enhanced sampling and free energy methods, and much more.

  • Artificial Intelligence in Precision Health

    From Concept to Applications
    • 1st Edition
    • March 4, 2020
    • Debmalya Barh
    • English
    Artificial Intelligence in Precision Health: From Concept to Applications provides a readily available resource to understand artificial intelligence and its real time applications in precision medicine in practice. Written by experts from different countries and with diverse background, the content encompasses accessible knowledge easily understandable for non-specialists in computer sciences. The book discusses topics such as cognitive computing and emotional intelligence, big data analysis, clinical decision support systems, deep learning, personal omics, digital health, predictive models, prediction of epidemics, drug discovery, precision nutrition and fitness. Additionally, there is a section dedicated to discuss and analyze AI products related to precision healthcare already available. This book is a valuable source for clinicians, healthcare workers, and researchers from diverse areas of biomedical field who may or may not have computational background and want to learn more about the innovative field of artificial intelligence for precision health.

  • Wood Microbiology

    Decay and Its Prevention
    • 2nd Edition
    • March 4, 2020
    • Robert A. Zabel + 1 more
    • English
    Wood Microbiology, Second Edition, presents the latest advances in wood decay and its prevention. Coverage includes classification of fungi and bacteria, factors affecting growth and survival, fungal metabolism, and wood chemistry. There are also chapters that focus on the anatomical aspects, chemical changes, and ultrastructural effects of wood decay. Additionally, this book discusses major issues associated with wood decay, detecting decay, and how to take protective action against it. This is a one-stop reference resource for wood scientists, wood processing and preserving professionals, foresters and forest pathologists, as well as students of forestry, and wood science and technology courses. It is authored by two leading experts with over 80 years of experience working with timber durability.

  • Gradients and Tissue Patterning

    • 1st Edition
    • Volume 137
    • March 4, 2020
    • English
    Gradients and Tissue Patterning, Volume 137 in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.

  • La maladie de Parkinson

    • 4th Edition
    • March 3, 2020
    • SOFMA + 2 more
    • French
    La maladie de Parkinson est, après la maladie d’Alzheimer, l’affection neurologique la plus répandue au sein de la population après 50 ans. Sa prévalence augmentant avec l’âge, surtout au-delà de 60 ans, on peut prévoir qu’avec le vieillissement de la population, le nombre de patients ne cessera d’augmenter dans les années à venir.La quatrième édition de cet ouvrage, entièrement en couleurs, consacrée à la maladie de Parkinson, rend compte de façon didactique des avancées de ces cinq dernières années, en abordant de façon exhaustive tous les aspects de cette pathologie : l’épidémiologie, l’étiopathogénie, les aspects génétiques, la physiopathologie, les signes moteurs et non moteurs, notamment les troubles cognitifs, psychiques et comportementaux. Un nouveau chapitre dédié aux apports des nouvelles technologies, notamment les enregistrements électrophysiologique... intracérébraux, l’évaluation neurophysiologique de la marche et du contrôle postural ou encore l’actimétrie, vient compléter cette monographie. Le chapitre consacré à la neuropathologie et la physiopathologie, est également entièrement augmenté et mis à jour avec l’approche de l’alpha-synucléine et l’évocation de la controverse autour de l’hypothèse d’un mécanisme de type prion. Les traitements de recours sont regroupés maintenant dans un chapitre spécifique et un nouveau chapitre est proposé sur les indications de la toxine botulique.Ce livre s’adresse aux praticiens et à tous les professionnels de santé, médicaux et paramédicaux, exerçant dans un service de neurologie ou concernés par la pathologie parkinsonienne : neurologues, internes préparant le diplôme d’études spécialisées de neurologie, neuropsychologues, psychiatres, rééducateurs, orthophonistes et kinésithérapeutes.

  • Vasopressin

    • 1st Edition
    • Volume 113
    • March 3, 2020
    • Gerald Litwack
    • English
    Vasopressin, Volume 113 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting updates on timely topics, including Diabetes Insipidus in Pregnancy, Vasopressin Inactivation: Role of Insulin-Regulated Aminopeptidase, Vasotocin and the Origins of the Vasopressin/Oxytocin Receptor Gene Family, Vasopressin V2 Receptor Ligand Recognition, Development and Therapeutic Potential of Vasopressin Synthetic Analog [V4Q5]dDAVP as a Novel Anticancer Agent, Cellular Junctions and Vasopressin, Vasopressin Actions in the Kidney Renin Angiotensin System and its Role in Hypertension and Renal Disease, Oxytocin/Vasopressin... Neuropeptide Signaling in Insects, and much more.

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