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Elsevier

Books in Life sciences

  • Biological Insights of Multi-Omics Technologies in Human Diseases

    • 1st Edition
    • Aarif Ali + 3 more
    • English
    Biological Insights of Multi-Omics Technologies in Human Diseases provides detailed information about the basics of multi-omic technologies, including ethics, historical perspective, science, drug discovery, and development and metabolism. With a strong focus on the practical application of omics approaches in cancer, cardiovascular, neurology, respiratory, viral, gastroenterology, autoimmune diseases, PCOS and tuberculosis, this book also includes special topics related to COVID-19 and Machine learning approaches. In 13 chapters, this book provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of multi-omics from academic, regulatory, pharmaceutical, socio-ethical, and economic perspectives.The chapters are designed in a well-defined chronology such that readers will intuitively understand the central idea. This book is an ideal resource for health professionals, scientists and researchers, nutritionists, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Targeting Signaling Pathways in Solid Tumors Part B

    • 1st Edition
    • Volume 386
    • English
    Targetting Signaling Pathways in Solid tumour Part B, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Pictorial Atlas of Neuroradiological Signs

    • 1st Edition
    • Athena Sharifi-Razavi + 2 more
    • English
    Pictorial Atlas of Neuroradiological Signs examines various brain scans in order to create a useful guide for clinicians and students. Using images of diseases and other conditions, this atlas is designed to identify various signs as well as explain what the underlying reason for the presentation of such anomalies on brain scans and images. This book will be most useful to clinicians in neurology and students who are studying neuroradiology. Those with an interest in various branches of neuroscience or radiology might also find this book a useful tool.

  • Brains and Machines: Towards a unified Ethics of AI and Neuroscience

    • 1st Edition
    • Volume 7
    • English
    Brains and Machines: Towards a unified Ethics of AI and Neuroscience provides a comprehensive overview of concepts and ethical issues at the intersection of two emerging technological trends in the 21st century: AI and neurotechnology. In line with recent advances across both fields, debates about philosophical, ethical, regulatory and social issues raised by neuroscience and AI have considerably expanded in the past decade. Yet, despite many intersections and fruitful interactions between the two scientific domains, ethical debates about neuroscience and AI have mostly moved in parallel. This volume assembles voices from various disciplines to provide a more unified view and offer novel perspectives on two complementary lines of discourse. The volume provides scientific background by outlining the state of the art of applying AI in the field of neuroscience and discussing instances where findings and debates from neuroscience provide cues and inspiration to the study of AI. Based on this background, the book then addresses conceptual frameworks, identifies ethical challenges at the intersection of neuroscience and AI, and highlights challenges and opportunities of finding common ground in interdisciplinary settings.

  • Regulatory T cells and Autoimmune Diseases

    • 1st Edition
    • Mitesh Kumar Dwivedi + 1 more
    • English
    Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies.This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.

  • New Approach for Drug Repurposing Part A

    • 1st Edition
    • Volume 205
    • English
    New approach for drug repurposing represents drug discovery and development which is a tedious process that requires 10-15 years of time, investments up to $1-2 billion, and have high risk of failure to enter into market for clinical applications. As the drugs has to pass through number of developmental phase, the likelihood for a drug to be approved from phase I clinical trial to United States of Food and Drug Administration (USFDA) approval is less than 10%. More than 90% of drugs failed in due to toxicity, efficacy and clinical trials. Drug repurposing is one of the roadway to accelerating drug discovery and development for treating disease and thus to providing better quality of life. This volume covers an overview of drug repurposing, novel methods, mechanism of action, lab on chip for drug repurposing, computational biology, system biology, artificial intelligence and machine learning for drug repurposing, target identification, target mining, high throughput drug screening, clinical trial of repurposed drug, repurposed biologics, and regulatory consideration and intellectual property right of repurposed drug. This volume highlights a number of aspects of the drug repurposing that can help the basic understanding of students, researchers, clinicians, entrepreneurs, and stakeholders to perform their research with great interest.

  • Neuroscience Without Representations

    Building a Brain-in-a-World View
    • 1st Edition
    • Óscar Vilarroya
    • English
    In Neuroscience Without Representations, an Open Access book, Oscar Vilarroya addresses the notion of “representation” as used in expressions like “neural representation” or “mental representation”. This concept is fundamental in neuroscience, yet there remains no clear, universally accepted view on what it means for a nervous system to represent something, what constitutes a neural activity as a representation, and what is being re-presented.The book lays the foundation for a non-representational view of brain function. Building upon György Buzsáki’s critique of the theoretical framework underlying current cognitive neuroscience, Vilarroya argues that disciplines such as embodied and embedded cognition—collective... known as ‘4E cognition’—are driving a paradigm shift in our understanding of animal cognition.Rather than grounding cognition solely in representations, the author proposes an alternative: understanding cognition as enaction—the meaningful engagement of an organism to address situational requirements. The book supports this approach through detailed analyses of recent studies.

  • Banana Peels Valorization

    Sustainable and Eco-friendly Applications
    • 1st Edition
    • Mejdi Jeguirim + 1 more
    • English
    Banana Peels Valorization: Sustainable and Eco-friendly Applications provides a global overview of world production, physicochemical and microbiological characteristics of Banana Peels and the various pathways for their valorization, considering the advantages, disadvantages and factors impacting on each way of valorization. Each chapter deals with sustainable applications based on the sector category. Such structure helps the audience from a specific field to easily identify the specific application. Successful case study of a banana processing by-products valorization is also presented. Written by a team of interdisciplinary experts, this is the ultimate valuable resource for agricultural or food engineers who work in the banana groves and in the banana processing industry, and also for Researchers working in correlated areas of food, environmental and energy fields.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 127
    • English
    Advances in Applied Microbiology, Volume 127 continues the comprehensive reach of this widely read and authoritative review source in microbiology where users will find invaluable references and information on a variety of areas relating to the topics of microbiology.

  • Pharmacology in Drug Discovery and Development

    Understanding Drug Response
    • 3rd Edition
    • Terry P. Kenakin
    • English
    Pharmacology in Drug Discovery and Development: Understanding Drug Response, Third Edition is an introductory resource that illustrates how pharmacology can be used to furnish the tools necessary to analyze different drug behavior and trace this behavior to its root cause or molecular mechanism of action. Chapters logically build upon one another to show how to characterize the pharmacology of any given molecule and allow for more informed predictions of drug effects in all biological systems. New chapters are dedicated to the interdisciplinary drug discovery environment in both industry and academia, and special techniques involved in new drug screening and lead optimization.The updates to the Third Edition include a new section converting “descriptive” data into “predictive” data through comparison to mathematical models, expansion on enzymes, drug metabolites and drug–drug interactions, and two new chapters. The newly developed companion website hosts further educational resources to complement the book. As in previous editions, this new edition includes numerous valuable chapter summaries, detailed references, practical examples, and case studies throughout.

  • Advances in Artificial Intelligence

    Biomedical Engineering Applications in Signals and Imaging
    • 1st Edition
    • Kunal Pal + 2 more
    • English
    Artificial intelligence in healthcare has become one of the best assisting techniques for clinicians in proper diagnosis and surgery. In biomedical applications, artificial intelligence algorithms are explored for bio-signals, such as electrocardiogram (ECG/EKG), electrooculogram (EOG), electromyogram (EMG), electroencephalogram (EEG), blood pressure, heart rate, and nerve conduction, and for bio-imaging modalities, such as computed tomography (CT), cone-beam computed tomography (CBCT), and MRI (magnetic resonance imaging). Advancements in artificial intelligence and big data have increased the development of innovative medical devices in healthcare applications. Advances in Artificial Intelligence: Biomedical Engineering Applications in Signals and Imaging provides an overview of arti­ficial intelligence in biomedical applications, including both bio-signals and bio-imaging modalities. The chapters contain a mathematical formulation of algorithms and their applications in the biomedical ­ eld, including case studies. Biomedical engineers, advanced students, and researchers can use this book to apply their knowledge in artificial intelligence-based processes to biological signals, implement mathematical models and advanced algorithms, and develop AI-based medical devices.

  • Nucleic acid associated mechanisms in immunity and disease

    • 1st Edition
    • Volume 161
    • English
    Advances in Immunity volume 161 highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Plant Biomass Applications

    Materials, Modification and Characterization
    • 1st Edition
    • Mohammad Jawaid + 2 more
    • English
    Plant Biomass Application: Materials, Modification and Characterization focuses on the unique properties associated with plant biomass, from their biodegradable, non toxic, and safe for handling characteristics to their potential in developing sustainable, climate protecting products. The book covers all aspects of plant biomass materials opportunities, with a focus on the value-added product generated from plant biomass such as polymers, composites, transportation fuels, chemical intermediates/bulk chemicals, or sources of heat and generated power. The conversion of plant biomass into materials product such as plastics, fabrics, and carpets and specialty chemicals presents exciting possibilities for replacing traditionally used fossil fuels. Sections in this new release provide in-depth discussion on the materials derived from plant biomass and their current and potential future applications. Leading researchers from industries, academics, government, and private research institutions across the globe provided insights, making it an important reference for researchers and academics seeking to maximize plant biomass potential.

  • Phylogenomics

    Foundations, Methods, and Pathogen Analysis
    • 1st Edition
    • Igor Mokrousov + 1 more
    • English
    Phylogenomics: Foundations, Methods, and Pathogen Analysis offers a deep overview of phylogenomics as a field, compelling recent developments, and detailed methods and approaches for conducting new research. Early chapters introduce phylogenomic analysis of viruses and bacteria, deciphering bacterial outbreaks, and evolution of drug resistance and virulence, with a second section on methods offering instruction in tools for SNP calling and dealing with big datasets, use of Bayesian approach in molecular epidemiology, bacterial evolution modeling and evolutionary reconstruction in the presence of mosaic sequences. Part 3 offers various examples of phylogenomic analysis across medically significant bacteria and viruses, including Yersinia pestis, Salmonella, Mycobacterium tuberculosis, HIV-1, measles virus as well as ancient pathogens research.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 120
    • English
    Advances in Clinical Chemistry, Volume 120, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

  • Immunology for Engineers

    • 1st Edition
    • Volume 140
    • English
    Immunology for Engineers, Volume 140 consists of chapters from stalwarts of the field, covering topics such as antibody engineering, adjuvant requirement and its methodology for assessment, and the need to develop immunotherapy, etc. Chapters covered in this volume discuss Current Status and Future Prospective of Breast Cancer Immunotherapy, Engineering high affinity antigen binders- beyond antibodies, Platelets and Inter-Cellular Communication in Immune Responses: Dialogue with both Professional and Non-Professional Immune Cells, Chimeric Antigen Receptor (CAR) T cell-based cancer immunotherapy: A boon for cancer-free life, and Molecular insights and promise of Oncolytic Virus based Immunotherapy.

  • Rang y Dale. Farmacología

    • 10th Edition
    • James M. Ritter + 4 more
    • Spanish
    Nueva edición del texto clásico en Farmacología y de referencia para los estudiantes de Medicina en el que se aborda de forma exhaustiva, pero clara y organizada el mecanismo de acción de los fármacos más comúnmente usados, tanto a nivel molecular o celular, como de los mecanismos fisiológicos sobre los que actúan.Se ha mantenido la organización general del libro, dividido en 6 grandes secciones en las que se ofrece una descripción de los efectos y usos de los diferentes fármacos junto con su acción sobre las vías de señalización subyacentes a todos los procesos fisiológicos que ocurren en el ser humano. En cuanto a las novedades, si bien todos los capítulos se han actualizado, algunos de ellos han sufrido grandes cambios. Así cabe destacar: Cap 5 (se han incluido un mayor número de fármacos RNA), Cap 24 (recientes avances en la medición de la presión de oxígeno), Cap 40 (se ha puesto el foco en el Alzheimer y la demencia vascular y la asociada a los cuerpos de Levy), Cap 43 (nueva sección destinada al tratamiento del dolor crónico), Cap 51 (nuevos diagramas que ilustran los lugares de acción de los antibióticos a nivel de los ribosomas), Cap 53 (información sobre el modo de replicación de los retrovirales y una sección específica de Covid19) y Cap 57 ( gran y amplia cobertura de los nuevos fármacos anticancerosos). Se ha introducido dos nuevos capítulos. Uno de ellos dedicado a la Farmacología ocular y otro dedicado al tratamiento farmacológico de la migraña en el que se incluyen los nuevos antagonistas de CGRP y su uso profiláctico para la migraña. La nueva edición incluye acceso al e-book en español en el que se incluye contenido adicional (casos clínicos y preguntas de autoevaluación) también en español.

  • Starch in Food

    Structure, Function, and Applications
    • 3rd Edition
    • Lars Nilsson
    • English
    Starch in Food: Structure, Function and Applications, Third Edition is now fully updated with eleven new chapters covering "hot" areas for starch applications, such as starch-based pickering emulsifiers, starch for structuring gluten-free bread products, and starch microspheres for encapsulation of probiotic bacteria. Sections illustrate how plant starch can be analyzed and modified, including chapters on analysis of starch molecular structure, molar mass and size, the relationship between structure and digestion of starch, sources of starch, including new chapters on cereal, root and tuber and pulse starches, and starch applications, with a new chapter on utilizing starches in product development, in baked products and in gluten-free bread. Starch selection is one of the most complex areas for a product developer, yet starch is key to solving formulation challenges when developing products to meet many of the emerging consumer trends. This book aids the end user on acquiring knowledge on fundamental starch aspects, such as granular and molecular structure and properties, analysis, biosynthesis and general functionality of starch in foods.

  • Handbook of Plant-Based Meat Analogs

    Innovation, Technology and Quality
    • 1st Edition
    • Gokare A. Ravishankar + 3 more
    • English
    Handbook of Plant-Based Meat Analogs: Innovation, Technology and Quality presents the growing opportunities and challenges of meat substitutes from plant-based resources. Addressing core topics from source ingredients to consumer acceptance, it provides a comprehensive starting point for those seeking to explore sustainable meat alternative products. To date, the full potential of plant-based meat products has been underexplored, underutilized, and underrepresented.Thi... book provides the most up-to-date information on plant-based meat analogs, sources of ingredients, industrial processes, large-scale production, and health benefits, including safety and regulatory aspects and environmental implications.

  • Grapevine

    From Origin to the Vineyard
    • 1st Edition
    • Volume 110
    • English
    Advances in Botanical Research: From Origin to the Vineyard, Volume 110 highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Grapevine origin and diversity, Climate change implications on the geography of viticulture, Canopy and soil management strategies insights into overcome abiotic stresses in grapevine, Grapevine defense mechanisms when challenged by pathogenic fungi and oomycetes, Management strategies for reducing pesticide use against diseases caused by fungi and oomycetes in grapevine, The Role of Plant Breeding in grapevine production, and New biotechnological tools for grapevine improvement.

  • Advances in Parasitology

    • 1st Edition
    • Volume 124
    • English
    Advances in Parasitology Volume 124, the latest release in this esteemed series, highlights new advances in the field, with this new release including chapters on Geomorphological determinants and geospatial analyses of mosquito habitat for control and elimination studies of malaria in Africa, Immunology and Pathology of Echinostomes and other Intestinal Trematodes, PfEMP1 – Still of key importance in Plasmodium falciparum malaria immunity and pathogenesis, and more.

  • An Integrated Guide to Human Drug Metabolism

    From Basic Chemical Transformations to Drug-Drug Interactions
    • 1st Edition
    • Mark Ashton + 3 more
    • English
    An Integrated Guide to Human Drug Metabolism: From Basic Chemical Transformations to Drug-Drug Interactions uses the chemistry of each of the metabolic transformations to underpin the discussion of drug interactions with foods, herbal medicines, and other drugs. Each of the human metabolic processes are covered, employing examples drawn from known metabolic transformations of drugs used clinically. The clinical relevance of metabolism is discussed, focusing on appropriate prescribing (age-related dosage adjustments, routes of administration, and personalized medicines). Appropriate for use in the classroom or for self-study, this book is for students and researchers needing a reference for interdisciplinary research in drug interactions.Metabol... is at the center of personalized medicine, as it is a governing factor in the response of the patient to a drug. For example, does the patient express the genes, and so enzymes, which are responsible for the metabolism of a drug? Do they express the genes responsible for the bioactivation of a prodrug into its active form? Examples of clinically used agents for which metabolic phenotyping is essential will be used to highlight the increasing necessity for understanding the genetic profile of individual patients. This book includes questions and answers to gauge learning of each chapter, real-life case studies, and the basic science as a basis for the discussion of clinical aspects.

  • Bioreactor Design Concepts for Viral Vaccine Production

    • 1st Edition
    • Surajbhan Sevda + 1 more
    • English
    Bioreactor Design Concepts for Viral Vaccine Production covers a range of interdisciplinary chapters from the engineering perspective of bioreactor design to the biotechnological perspectives of vector design for vaccine development. The book covers bioreactor concepts such as static systems, single-use systems, stirred tanks, perfusion, wave and packed-beds. It reviews options for efficient and economical production of human vaccines and discusses basic factors relevant for viral antigen production in mammalian cells, avian cells, and insect cells. This book will be a great resource for those interested in implemented novel bioreactor design or experimental schemes towards intensified or/and enhanced vaccine production.

  • Advanced Biologic Drugs and Manufacturing Process

    • 1st Edition
    • Basanta Kumara Behera
    • English
    Advanced Biologic Drugs and Manufacturing Process explains biologic drugs, their pharmaceutical charters, and their significance in curing life-threatening chronic diseases. It also provides the latest information on the use of biological drugs for the treatment of numerous diseases and conditions and their most advanced therapies available, including how biologics have impacted cancer therapy, delayed or reversed the course of immune-related conditions, and changed the lives of those with rare chronic diseases. In addition, the book explains how immunotherapy is used for the treatment of diseases by activating or suppressing the immune system.Scientists working on the front lines in the biotechnology industry are provided with an overview on stable production processes and how to monitor the value chain transfer process of biologic drug for better return, in terms of profit. The book also helps researchers and academics on how to develop and update protocols related to testing, quality control, and quality assurance to obtain highly purified biopharmaceuticals or vaccines.

  • Environmental Pollution and Type 2 Diabetes Mellitus

    • 1st Edition
    • Sultan Ayoub Meo
    • English
    Environmental Pollution and Type 2 Diabetes Mellitus elucidates on the global impact of environmental pollution and how it increases diabetes mellitus. Swift urbanization and the industrial revolution have increased environmental pollution to a hazardous level. Environmental pollution is a leading risk factor for several well-known diseases. This book opens venues for students, physicians, researchers, the science community, and policymakers to enhance their knowledge about environmental pollution, weather conditions, climate change, and their impact on insulin resistance and mechanisms allied to Type 2 diabetes mellitus (T2DM).Moreover, this book will provide knowledge about the green space environment and its impact on T2DM.

  • Vertebrate Pattern Formation

    • 1st Edition
    • Volume 159
    • English
    Vertebrate Pattern Formation, Volume 159 in the Current Topics in Developmental Biology series, highlights advances in the field, with this volume presenting interesting chapters on timely topics, including Hox genes patterning the vertebrate body, Endodermal patterning, The use of organoids/gastruloid... to understand development, Cell shape and movements controlling development, Neural crest and placodes in vertebrate development, Patterning of the neural tube, Non-canonical Wnt signaling in axial extension, The control of transitions along the main body axis, Emergence of a left-right symmetric body plan in vertebrate embryos, Formation of the vascular system, Generation of patterns in the paraxial mesoderm, and more.

  • Bioremediation of Emerging Contaminants from Soils

    Soil Health Conservation for Improved Ecology and Food Security
    • 1st Edition
    • Prasann Kumar + 4 more
    • English
    Bioremediation of Emerging Contaminants from Soils: Soil Health Conservation for Improved Ecology and Food Security deals with current challenges of sustainable soil health using eco-friendly approaches. This book provides ways of reducing the chemical burden on the soil by maintaining balance in terms of society, environment, and economy, which are considered basic pillars of sustainability.Desig... to highlight soil health best practices for both environmental and agricultural sustainability, these approaches are also considered important for improving global food security by ensuring safe growing conditions for crops for food and feed. Presented in two parts, this book first highlights emerging contaminants and their sources. The second part explores a variety of steps and tools for addressing contaminated soils, including bio- and phytoremediation options. Case studies in each part provide real-world insights for practical application.

  • Current Omics Advancement in Plant Abiotic Stress Biology

    • 1st Edition
    • Deepesh Bhatt + 3 more
    • English
    Current Omics Advancement in Plant Abiotic Stress Biology investigates the causal molecular factors underlying the respective mechanisms orchestrated by plants to help alleviate abiotic stress. Despite available knowledge of abiotic stresses in crop plants and high throughput tools and biotechnologies, in this book, a systematic effort has been made for integrating omics interventions across major sorts of abiotic stresses with special emphasis to major food crops infused with detailed mechanistic understanding, which would furthermore help contribute in dissecting the interdisciplinary areas of omics-driven plant abiotic stress biology in a much better manner.It focuses on the integration of multi-OMICS biotechnologies in deciphering molecular intricacies of plant abiotic stress, namely drought, salt, cold, heat, and heavy metals in major C3 and C4 food crops. Together with this, the book provides updated knowledge of a common and unique set of molecular intricacies playing a vital role in coping up severe abiotic stresses in plants deploying multi-OMICS approaches.

  • Nanobiotechnology for Food Processing and Packaging

    • 1st Edition
    • Jay Singh + 4 more
    • English
    Nanobiotechnology for Food Processing and Packaging covers nanomaterials' application as an eco-friendly, greener, cost-effective and easy handling and management approach that can help prevent various high-level physical, biological and chemical contamination in foodstuff. Written by experts from a multidisciplinary perspective, each chapter addresses nanomaterials' application as a sustainable tool for the management of uncountable food processing and packaging challenges. Sections focus on nanobiotechnology in processing and packaging, considering food quality, safety and management aspects. The book also highlights various preparative methods and antimicrobial/antifu... activities, including the mechanism of the antimicrobial action of various bionanocomposites and food toxin detection nanobiosensor nano additives.Other sections cover possible food toxin detection, food packaging, and materials such as nanomaterials, nanocomposites, carbon-based nanomaterials, polymer-based nanocomposites and various binary and tertiary nanocomposites and their mechanistic approach.

  • Neurovision chez l'enfant et troubles des apprentissages

    • 1st Edition
    • Michèle Mazeau + 1 more
    • French
    L'ouvrageLa vision est à la fois l’un de nos meilleurs outils pour explorer notre environnement et un ressort capital des apprentissages.Souve... masqués, ne se révélant alors que par des troubles des apprentissages, les dysfonctionnements neurovisuels sont complexes et pluriels, pouvant concerner l’attention visuelle ou visuo-spatiale, les stratégies d’exploration visuelle, l’organisation visuo-spatiale du geste ou encore l’interprétation des images rétiniennes (gnosies).Cet ouvrage aborde ainsi en trois temps les liens entre neurovision et troubles des apprentissages chez l’enfant :• l’analyse du message visuel à partir du chiasma optique, la description des voies empruntées et des connexions cérébrales ;• les méthodes d’exploration des fonctions visuelles et neurovisuelles ainsi que l’interprétation des bilans spécifiques ;• l’impact de ces troubles dans les apprentissages scolaires (dyslexies/dysorthog... dyspraxies, dyscalculies), les caractéristiques de leurs manifestations cliniques, ainsi que les principales stratégies d’aide pour un accompagnement efficace des jeunes concernés.Le publicL’objectif est ici de proposer aux psychologues-neurops... médecins (pédiatres et médecins traitants, médecins scolaires, médecins des PCO, des CRTLA, de la MDPH), rééducateurs (orthophonistes, ergothérapeutes, psychomotriciens et orthoptistes), les données qui leur permettront de comprendre et prendre en charge les troubles neurovisuels dans le cadre plus large des troubles neurodéveloppementau... auteursMichèle Mazeau est médecin de rééducation, neuropsychologie de l’enfant (TND : dys et troubles des apprentissages, https://dr-michele-m... Dalens est ophtalmologiste des hôpitaux, centre de rééducation pour déficients visuels et Sessad Victor-Duruy, Clermont-Ferrand.

  • Progress and Prospect of Nanocarriers

    Design, Concept, and Recent Advances
    • 1st Edition
    • Sushil K. Kashaw + 2 more
    • English
    Progress and Prospect of Nanocarriers: Design, Concept, and Recent Advances examines the different nanocarriers that are currently being developed for specific applications in biomedical drug delivery, disease management, diagnosis and therapy. Nanosized drug delivery systems have gained tremendous amounts of clinical interest due to their effective bio-distribution and enhanced pharmacokinetic and selective targeting capability which results in high therapeutic potential, low side effects, and the generation of cost-effective drug delivery systems. Numerous effective nanocarriers have been evolving, including polymeric nanoparticles, liposomes, microspheres, dendrimers, and carbon nanotubes.This book is a helpful reference for scientists and students in the fields of drug delivery, biomaterials and nanomedicine, as well as scientists and engineers in industrial disciplines of drug delivery and drug formulation.

  • Biocatalysis in Asymmetric Synthesis

    • 1st Edition
    • Gonzalo De Gonzalo + 1 more
    • English
    Biocatalysis in Asymmetric Synthesis, a new volume in the Foundations and Frontiers of Enzymology series, offers an applied discussion on synthesizing biological catalysts using asymmetric synthesis for varying applications. Here, global experts in the field analyze a wide variety of biocatalysts and their physical states, process conditions for their asymmetric synthesis, solvents required during synthesis, and even downstream procedures for the recovery of final products. The book adopts an interdisciplinary approach, merging fundamental biology and its synthetic applications across industries with a wide range of practical examples, from directed evolution to biotransformation and production of novel enzymes and non-conventional catalysts. Throughout the book, the impact and application of biocatalysis in sustainable processing is considered in-depth. This book will also help non-experts in biocatalysis to apply this knowledge in their own research, providing a thorough overview of the ways asymmetric biocatalytic approaches may be adapted for different disciplines and downstream products.

  • Integrative Omics

    Concept, Methodology, and Application
    • 1st Edition
    • Manish Kumar Gupta + 3 more
    • English
    Integrative Omics: Concept, Methodology and Application provides a holistic and integrated view of defining and applying network approaches, integrative tools, and methods to solve problems for the rationalization of genotype to phenotype relationships. The reference provides systemic ‘step-by-step’ coverage that begins with basic concepts from Omic to Multi Integrative Omics approaches followed by applications and emerging and future trends. All areas of Omics are covered, including biological databases, sequence alignment, pharmacogenomics, nutrigenomics and microbial omics, integrated omics for Food Science and Identification of genes associated with disease, clinical data integration and data warehousing, translational omics, technology policy, and society research. This book covers recent concepts, methodologies, advancements in technologies and is also well-suited for researchers from both academic and industry background, undergraduate and graduate students who are mainly working in the area of computational systems biology, integrative omics and translational science.

  • Microbial Vitamins and Carotenoids in Food Biotechnology

    Novel Source and Potential Applications
    • 1st Edition
    • Syed Amir Ashraf + 1 more
    • English
    Microbial Vitamins and Carotenoids in Food Biotechnology: Novel Source and Potential Applications provides important insights to help readers understand the molecular mechanisms involved in the microbial biosynthesis of vitamins and carotenoids. The book's chapters put forward all the latest advancements concerning the production and applications of microbial vitamins and carotenoids. It also provides a sustainable alternative to chemically synthesized compounds and presents wide coverage on the most promising sources of vitamins and carotenoids in food and pharmaceutical industries.This is a complete and unique resource beneficial for the scientific communities as well as food science and nutrition research students.

  • Cranial Surgery - Part 2

    • 1st Edition
    • Volume 285
    • English
    This is a study of the evolution of the principles and techniques of cranial surgery from Hippocrates to the nineteenth century. The methods of conveying information by text and image are considered.

  • Colorimetric Sensors

    Techniques to Measure Food Safety and Quality
    • 1st Edition
    • Haroon Elrasheid Tahir + 3 more
    • English
    Colorimetric Sensors: Techniques to Measure Food Safety and Quality explores the latest advancements in colorimetric sensors/indicators and their applications. It consolidates state-of-the-art developments and current approaches in the fabrication of colorimetric sensors/indicators for cutting-edge applications. This book documents the principles of colorimetric sensors, sensor fabrication and characterization, sensitivity and detection limits of colorimetric sensors based on natural pigments, synthetic dyes, and nanotechnologies, as well as safety, quality controls, and regulatory aspects, followed by an assessment of their safety and quality. In addition, global trends in the application of colorimetric sensors in monitoring food freshness, challenges, marketing, and potential future development applications are addressed in detail. How the applications of colorimetric sensors/indicators in the analysis of cereal and cereal-based products, meat and meat products, liquid and semiliquid foods, food authentication, food toxicants, and pathogens, among others, is also discussed. This book can be used as a textbook for graduate students, a reference book for medical biologists, nanobiotechnologists... nanoengineers, agricultural scientists, and general biologists, and an inspiration for industrialists and policymakers studying smart nanomaterials. Graduate students and food scientists of all levels will also benefit.

  • Encyclopedia of Sustainable Technologies

    • 2nd Edition
    • Martin Abraham
    • English
    While technological advancement leads to societal benefits in terms of economic growth, it also brings with it challenges in its impact on the environment or human health. Sustainable development seeks a uniform means of comparing the economic benefits with the environmental and health costs associated with the implementation of a new technology.This revised encyclopedia investigates sustainability initiatives across a range of industries, providing insight into future opportunities for technological development. A broad spectrum of human challenges have only become more intense since publication of the first edition. For example, climate change is now observed across the globe as a contributor to large scale weather events, including extreme drought in Australia, intense wildfires in California, and flooding along the great rivers of Africa, North and South America. Land in the Amazon rain forest is destroyed to provide increased cropland, contributing to climate change. Expansion of the use of biomass as a raw material in chemical processing leads to food shortages. In many cases, these challenges have the greatest impact on the poorest nations, and the most polluting manufacturing facilities are located in the poorest communities, demonstrating social justice challenges.Encyclope... of Sustainable Technologies, Four Volume Set provides a comprehensive analysis of the challenges of modern technology, and the innovations that are leading to better use of limited resources and improved resiliency as we learn to adapt to a changing world. Each chapter examines in depth a technological solution to support a specific human need, evaluates it relative to its impacts on the environment and human health, and considers the social justice issues underlying its development.The new edition provides a stronger link between manufacturing and climate change, updates on new technologies for the generation, distribution and storage of energy, new concepts in resiliency and modularity that have changed manufacturing and chemical processes, and emphasizes the trade-offs required to obtain desired products while minimizing environmental impact.

  • Clinical Genomics

    A Guide to Clinical Next Generation Sequencing
    • 2nd Edition
    • Shashikant Kulkarni + 1 more
    • English
    Clinical Genomics, Second Edition is a comprehensive, practical reference [AN1] designed specifically for laboratory directors, clinical medical directors, and genomic medicine professionals. Edited by renowned genomic pathology leaders Kulkarni and Roy, this updated edition offers clear guidance on the current technical, bioinformatic, clinical, regulatory, and reimbursement considerations involved in implementing next-generation sequencing technologies within clinical molecular diagnostic laboratories.Structu... for ease of reference, this book covers targeted gene sequencing methods, whole exome/genome approaches, emerging technologies such as long-read sequencing, and critical considerations for assay validation. Detailed sections address bioinformatics workflows, variant detection and interpretation methodologies, integration with clinical informatics systems, and essential IT infrastructure, including cloud-based solutions.This book also thoroughly addresses practical topics essential to laboratory management, such as regulatory compliance, ethical frameworks, billing strategies, and reimbursement paradigms, helping directors navigate the evolving landscape of genomic diagnostics.

  • Unit Operations in Food Grain Processing

    • 1st Edition
    • C.K. Sunil + 4 more
    • English
    Unit Operations in Food Grain Processing covers theory and principles as well as best practices in cleaning, grading, drying, storage, milling, handling, transportation, and packaging of grains. The book begins with an overview of grain types, grain structure and composition, and engineering properties of different grains. It then moves into the aspects of processing. It reviews best practices in processing rice, wheat, pulses, oilseeds, millets, and pseudocereals. The book discusses value addition methods, products of grains, and waste and by-product utilization from grains. These discussions outline equipment and machinery needed, different methods of operations for various grains, and advances in grain processing as well as grain waste and by-product utilization.The book has 18 chapters in total. Each chapter discusses principles, design, illustrations, advances, and challenges to aid in understanding. Therefore this book is a valuable reference material for academicians, researchers, consultants, manufacturers, and practitioners in the field of food processing.

  • Early and Late Presentation of Physical Changes of Puberty: Precocious and Delayed Puberty Revisited, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 53-2
    • Peter A. Lee + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics of North America, guest editors Drs. Peter A. Lee and John S. Fuqua bring their considerable expertise to the topic of Precocious and Delayed Puberty Revisited. Top experts provide practical discussions of physical evidence of early or late pubertal development, offering a reasonable approach to patients presenting with these chief complaints.

  • Focal Neuropathies

    • 1st Edition
    • Volume 201
    • English
    Facial Neuropathies, Volume 202 summarizes research and treatment on focal neuropathies to update clinicians on nerve biology and new diagnostic techniques to guide investigation and treatment of mononeuropathies. The book explores research broadly applicable to all types of mononeuropathies as well as individual mononeuropathy syndromes. Chapters on individual mononeuropathies include anatomy, causes, controversial diagnoses, and current or potential future treatments.

  • The Microbiome and Neurotoxicity

    • 1st Edition
    • Volume 11
    • English
    Advances in Neurotoxicology, Volume 11 presents interesting chapters written by an international board of authors. Chapters in this new release include Gut microbiota as a mediator on the neurotoxicity of mercury, Relationships between lead-induced learning and memory impairments and gut microbiota disturbance in mice, Utility of zebrafish-based models in understanding molecular mechanisms of neurotoxicity mediated by the gut-brain axis, Alterations of gut microbiota linking environmental exposures to neurotoxicity, Iron Toxicity, Ferroptosis and Microbiota in Parkinson’s Disease: Implications for Novel Targets, and Modulation of gut microbiota with probiotics as a strategy to counteract endogenous and exogenous neurotoxicity.

  • Correlative Light and Electron Microscopy V

    • 1st Edition
    • Volume 187
    • Thomas Müller-Reichert + 1 more
    • English
    Correlative Light and Electron Microscopy V, Volume 187 in the Methods in Cell Biology series, highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Orthotopic brain tumor models derived from glioblastoma stem-like cells, RNA sequencing in hematopoietic stem cells, Generation of inducible pluripotent stem cells from human dermal fibroblasts, In vitro preparation of dental pulp stem cell grafts combined with biocompatible scaffolds for tissue engineering, Gene expression knockdown in chronic myeloid leukemia stem cells, Identification and isolation of slow-cycling GSCs, Assessment of CD133, EpCAM, and much more.

  • Innovating Health Against Future Pandemics

    • 1st Edition
    • Simona Mellino + 3 more
    • English
    Innovating Health Against Future Pandemics covers the key aspects which drive heterogeneity in an individual's response to COVID-19, including age, sex, genetic makeup, immune responses, comorbidities, and viral strains/loads. This book also reviews the case examples from other disciplines to highlight areas where precision medicine and AI could be applied for the improvement of pandemic management. This includes research, primary and secondary prevention, isolation/tracking, hospitalization and patient management, diagnosis, and treatments. Lastly, drawing on past experiences for each of the areas this book provides practical recommendations to manage future pandemics.COVID-19 offered an unprecedented occasion to test the impact of digitally enabled solutions within precision medicine for public health and for accelerating their deployment and adoption.

  • Essential Minerals in Plant-Soil Systems

    Coordination, Signaling, and Interaction under Adverse Situations
    • 1st Edition
    • Azamal Husen
    • English
    Essential Minerals in Plant-Soil Systems: Coordination, Signaling, and Interaction under Adverse Situations is the first book to encompass these key aspects of plant science, biochemistry, soil science and fertilizer development in a single volume. Describing the micro- and macronutrients in the plant-soil system with the help of suitable illustrations, the book connects all the pieces enabling comprehensive and connected understanding. Sections cover recent advances in the understanding of how plants coordinate the acquisition, transport, signaling, and interaction, and cross-talks between macro‐ and micro-nutrients in adverse environmental situations.This book is a valuable reference for those putting research into practice in addressing stress situations, as well as providing important foundational insights for further research.

  • Innovation in Anesthesiology

    Technology, Development, and Commercialization Handbook
    • 1st Edition
    • English
    Innovation in Anesthesiology: Technology, Development, and Commercialization Handbook reflects recent trends of industry globalization and value-conscious healthcare. Written by a team of leading anesthesiologists, engineering development professionals, business analysts, commercialization experts, regulatory and reimbursement specialists, and legal authorities, this volume in the Clinical and Medical Innovation series provides a clear process for the identifi cation, invention, and implementation of new solutions in anesthesiology. This is the ideal resource for anesthesiology innovators who desire to deliver patient solutions and applications to their inventions. Featured case studies on innovative products highlighting the stages required are included for reference.The book will lead researchers, clinicians, entrepreneurs, and investors through a clear process for the identification, invention, and implementation of new clinical technology solutions. Expert medical device inventor/entrepreneu... provide case studies on globally innovative products including successes, failures and practical advice. The book will be a key reference for entrepreneurs developing emerging technology in anesthesia, investors funding innovation in anesthesia, life science business leaders seeking to understand market trends in technology development, tech transfer offices determining prioritization of patenting dollars, distributors seeking to understand trends in anesthesia technology, as well as researchers and engineers seeking to understand market development needs and trends.

  • Food Sustainability and the Media

    Linking Awareness, Knowledge and Action
    • 1st Edition
    • Marta Antonelli + 1 more
    • English
    **2025 PROSE Award Finalist in Media and Cultural Studies**Food Sustainability and the Media: Linking Awareness, Knowledge and Action is the first book to explore the roles that the media plays in raising awareness, spurring action, and increasing understanding about food security and global sustainability issues. The book addresses the means of leveraging traditional and new media to advance food and sustainability discourse by linking awareness, knowledge, and action. The book links sustainability and food security in media communication to address different topics, including the way climate change is framed by the media, key factors of success and failure in NGOs, public and corporate communication, and climate change denial.

  • Reproducibility in Biomedical Research

    Epistemological and Statistical Problems and the Future
    • 2nd Edition
    • Erwin B. Montgomery Jr.
    • English
    Reproducibility in Biomedical Research: Epistemological and Statistical Problems, Second Edition explores the ideas and conundrums inherent in scientific research. This second edition addresses new challenges to reproducibility in biosciences, namely reproducibility of machine learning Artificial Intelligence (AI), reproducibility of translation from research to medical care, and the fundamental challenges to reproducibility. All current chapters are expanded to cover advances in the topics previously addressed. This book provides biomedical researchers with a framework to better understand the reproducibility challenges in the area. Newly introduced interactive exercises and updated case studies help students understand the fundamental concepts involved in the area.

  • Therapeutic Drug Monitoring

    Newer Drugs and Biomarkers
    • 2nd Edition
    • Amitava Dasgupta
    • English
    Therapeutic Drug Monitoring: Newer Drugs and Biomarkers, Second Edition is an updated reference on TDM analytical techniques in diverse clinical settings. This new edition reviews exciting new developments in the area, including seven new chapters covering immunoassay design and applications, combined chromatographic techniques in therapeutic monitoring, drug monitoring in alternative specimens, pharmacogenomics of anticancer drugs, pharmacogenomics testing for patient management, selected antifungal agents, pharmacodynamic monitoring, and therapeutic drug monitoring of selected anticoagulants. All remaining chapters in the first edition were thoroughly revised and updated.This book is the ideal reference for clinical pathologists, pharmacologists, and toxicologists involved with TDM. Scientists working in diagnostic companies, developing reagents for monitoring therapeutic drugs will also find relevant information in this book.

  • Pepper Virome

    Molecular Biology, Diagnostics and Management
    • 1st Edition
    • Akhtar Ali + 1 more
    • English
    Pepper Virome: Molecular Biology, Diagnostics and Management presents detailed information about the plant viruses that infect pepper worldwide, providing crucial insights for both the scientific community and producers. Understanding the nature of the viruses, their transmission methods, and possible sources of resistance in order to minimize the yield losses as well as to reduce the spread of these viruses to new locations or countries is of global importance. Pepper is an important commodity worldwide, cultivated for both fresh produce and for processing industry as a spice. However, various diseases affect pepper production and cause significant yield losses in pepper yield.The increasing outbreaks of virus species infecting Capsicum spp. have become a major problem for growers. A combination of factors, including expansion and intensification of pepper cultivation, availability of volunteer hosts, abundance of insect vectors, and climate change have all contributed to the issue. This book provides in-depth information on both the viruses infecting peppers and eco-friendly management measures to decrease the rate of spread of viruses.

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