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Books in Life sciences

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  • Neuronal Chloride Transporters in Health and Disease

    • 1st Edition
    • Xin Tang
    • English
    In the past several years, there has been an exciting body of new research that links impairments in the expression or function of neuronal chloride transporters to a growing number of diseases spanning from autism to brain aging. This book introduces the core concepts and highlights the recent advances in understanding the physiology and pathophysiology of the KCC and NKCC families of neuronal chloride transporters. Neuronal chloride transporter biology is reviewed, including roles in setting the transmembrane chloride gradient and the chloride transport-independen... functions, such as regulating excitatory neurotransmission. Chapters are also dedicated to addressing the structure, post-translational modification, membrane trafficking, and protein interaction partners of neuronal chloride transporters, as well as the genetic and environmental factors that regulate their expression in neurons and the novel therapeutic approaches that target neuronal chloride transporters to treat neurological diseases. This new volume will provide readers with an up-to-date summary of the recent advances in neuronal chloride transporter research, with particular emphasis on some of the key emerging topics in the field.

  • Human Pluripotent Stem Cell Derived Organoid Models

    • 1st Edition
    • Volume 159
    • English
    Human Pluripotent Stem Cell Derived Organoid Models, Volume 159 highlights recent and emerging advances that describe organoid differentiation protocols for the different organ systems that implement organoids as tools to understand complexity and maturation, high content drug screening, disease modeling, development and evolution. Specific chapters in this new release include Pluripotent stem cell derived gastric organoids, Pluripotent stem cell derived esophageal organoids, Pluripotent stem cell derived small intestinal organoids, Pluripotent stem cell derived colonic organoids, Pluripotent stem cell intestinal organoids with an Enteric Nervous System, Pluripotent stem cell derived airway organoids, Pluripotent stem cell derived alveolar organoids, and much more.

  • Transgenic Technology Based Value Addition in Plant Biotechnology

    • 1st Edition
    • Usha Kiran + 2 more
    • English
    Transgenic Technology Based Value Addition in Plant Biotechnology discusses the principles, methodology and applications of transgenic technologies. With step-by-step methods on genome editing techniques and a range of potential applications, from improving crop yield to increasing therapeutic efficacy, this book is a one-stop reference for plant gene editing technologies. It will be of particular interest to researchers interested in plant biotechnology and plant genetics, as well as agricultural scientists and those concerned with medicinal plants.

  • Wheat - An Exceptional Crop

    Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects
    • 1st Edition
    • Herbert Wieser + 2 more
    • English
    Wheat - An Exceptional Crop: Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects presents the exceptional position of wheat among food crops. The book demonstrates the benefits and drawbacks of wheat from a wheat science, nutrition and technology perspective. Organized into 13 chapters, chapters 1 - 3 present a basic overview of wheat; chapters 4 - 6 explore the overall benefits of wheat for the general population, and chapters 7 - 13 assess wheat-related disorders that affect a small portion of the population. Wheat - An Exceptional Crop: Botanical Features, Chemistry, Utilization, Nutritional and Health Aspects is an exceptional reference for those working in and researching the fields of agronomy, food chemistry, food technology, nutrition, allergology and gastroenterology.

  • Artificial Intelligence in Cancer

    Diagnostic to Tailored Treatment
    • 1st Edition
    • Smaranda Belciug
    • English
    Artificial Intelligence in Cancer: Diagnostic to Tailored Treatment provides theoretical concepts and practical techniques of AI and its applications in cancer management, building a roadmap on how to use AI in cancer at different stages of healthcare. It discusses topics such as the impactful role of AI during diagnosis and how it can support clinicians to make better decisions, AI tools to help pathologists identify exact types of cancer, how AI supports tumor profiling and can assist surgeons, and the gains in precision for oncologists using AI tools. Additionally, it provides information on AI used for survival and remission/recurrence analysis. The book is a valuable source for bioinformaticians, cancer researchers, oncologists, clinicians and members of the biomedical field who want to understand the promising field of AI applications in cancer management.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 98
    • English
    Advances in Clinical Chemistry, Volume 98, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry. It is the benchmark publication for novel analytical approaches in the clinical laboratory.

  • Camptothecin and Camptothecin Producing Plants

    Botany, Chemistry, Anticancer Activity and Biotechnology
    • 1st Edition
    • T. Pullaiah + 4 more
    • English
    Camptothecin and Camptothecin Producing Plants: Botany, Chemistry, Anticancer Activity and Biotechnology provides updated information on camptothecin yielding plants, chemical diversity of camptothecin, extraction and exploitation methods, biosynthesis, biotechnological production and enhancement for drug delivery, and the pharmacological properties of the drugs. The book focuses on camptothecin anticancer properties based on recent developments of biotechnology. Topics emphasize anticancer activities, biosynthesis, potent derivatives currently undergoing experimental phases, and biotechnological methods to enhance the production. This book is a valuable source for cancer researchers, oncologists, biotechnologists, pharmacologists and members of the biomedical field who are interested in camptothecin and its applicability in cancer treatment.

  • Autophagy in Health and Disease

    • 1st Edition
    • Volume 172
    • English
    Autophagy in Health and Disease, Volume 175, presents the latest insights from renowned experts in the field who discuss the key role of autophagic responses in the preservation of cellular and organismal homeostasis and how defects in the molecular apparatus for autophagy drive or accompany disease. Specific chapters in this new release include Crosstalk between autophagy and cell death signaling: mechanisms and therapeutic relevance, C. elegans to model autophagy-related human disorders, Autophagy in Kidney Disease: advances and therapeutic potential, Autophagy in Chronic Lung Disease, Autophagy in motoneuronal disorders, Strategies employed by viruses to manipulate autophagy, and much more.

  • Encyclopedia of Bone Biology

    • 1st Edition
    • Mone Zaidi
    • English
    Encyclopedia of Bone Biology, Three Volume Set covers hot topics from within the rapidly expanding field of bone biology and skeletal research, enabling a complete understanding of both bone physiology and its relation to other organs and pathophysiology. This encyclopedia will serve as a vital resource for those involved in bone research, research in other fields that cross link with bone, such as metabolism and immunology, and physicians who treat bone diseases. Each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from advanced undergraduate students to research professionals. Chapters also explore the latest advances and hot topics that have emerged in recent years, including the Hematopoietic Niche and Nuclear Receptors. In the electronic edition, each chapter will include hyperlinked references and further readings as well as cross-references to related articles.

  • Ureteroceles

    Contemporary Diagnosis and Management
    • 1st Edition
    • Michael P. Leonard + 1 more
    • English
    Ureteroceles: Contemporary Diagnosis and Management provides an evidence-based review of current diagnosis and management options for patients with ureteroceles. With the advent of antenatal ultrasound screening, ureteroceles are presenting earlier, often in asymptomatic patients, proving the need for active surveillance. With no fixed protocols and guidelines currently in the field, this important reference brings together recent techniques, such as in utero puncture, endoscopic laser fenestration, and laparoscopic clipping of the upper moiety ureter. Case studies illustrate various diagnostic and management options. This important reference provides all the necessary resources for ureterocele diagnosis and management needed by urology researchers, pediatric urologists, and general surgeons.

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