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Books in Life sciences

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    • Medicinal and Aromatic Plants

      • 1st Edition
      • May 12, 2020
      • Tariq Aftab + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 5 9 0 1
      • eBook
        9 7 8 0 1 2 8 2 2 7 7 5 6
      Growing consumer interest in organic and herbal-based products has led to great demand in the botanicals industry in the past few years. However, the growing number of products utilizing medicinal and aromatic plants (MAPs) has threatened an estimated 9,000 medicinal plant species worldwide, making it critical to reevaluate their research and development, production, and utilization. Continuing advances in Omics methodologies and instrumentation are essential to understanding how plants cope with the dynamic nature of their growing environment, how yields and characteristics can be improved, and how to most effectively direct conservation efforts. With a focus on metabolomics, genomics, proteomics, transcriptomics, and more, Medicinal and Aromatic Plants: Expanding Their Horizons through Omics illustrates the genetic mechanisms of MAPs, providing a better understanding of MAPs conservation and methods to improve characteristics for medical applications. With an introduction on the role of MAPs in human health, subsequent chapters discuss using proteomics to increase MAP yields and plant quality, genome editing, and CRISPR/Cas9. A valuable resource for farmers, scientists, chemists, biochemists, pharmacists, and students interested in medicinal and aromatic plants and plant biology, Medicinal and Aromatic Plants: Expanding Their Horizons through Omics ensures readers have the background knowledge to put the necessary methodologies into practice themselves.

    • Genome Plasticity in Health and Disease

      • 1st Edition
      • April 7, 2020
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 8 1 9 5
      • eBook
        9 7 8 0 1 2 8 1 7 8 2 0 1
      Genome Plasticity in Health and Disease provides a fully up-to-date overview on genome plasticity and its role in human physiology and disease. Following an introduction to the field, a diverse range of chapters cover genomic and epigenomic analysis and the use of model organisms and genomic databases in studies. Specific molecular and biochemical mechanisms of genome plasticity are examined, including somatic variants, De Novo variants, founder variations, isolated populations dynamics, copy-number variations, mobile elements, DNA methylation, histone modifications, transcription factors, non-coding RNAs, telomere dynamics and RNA editing. Later chapters explore disease relevance for cancer, as well as cardiovascular, neuropsychiatric, inflammatory, and endocrine disease, and associated pathways for drug discovery.

    • Dietary Sugar, Salt and Fat in Human Health

      • 1st Edition
      • March 6, 2020
      • Harry G. Preuss + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 9 1 8 6
      • eBook
        9 7 8 0 1 2 8 1 6 9 1 9 3
      Divided into four main sections, Dietary Sugar, Salt and Fat in Human Health explores the biochemical, pharmacological and medicinal aspects related to the overindulgence of dietary salt, sugar, and fat, along with possible remedies. Beginning with a general overview, the text outlines aspects associated with advancing age and human physiology, such as different aspects of insulin resistance, the advancing age phenomenon, central fat accumulation and metabolic perturbations and the role of the modern Western diet and the influence of dietary sugar, salt, and fat, with particular focus on their relation to multiple biochemical pathophysiological pathways. The second section of the book focuses on the roles of dietary sugars and their correlation with the chronic disease epidemic, with an emphasis on carbohydrate metabolism and its biochemistry, GI absorption, the glycemic index and the influence of fructose. The historical background of dietary sugars is discussed alongside Atkin’s hypothesis, and an overview of the correlation between dietary fibre and the glycemic index, including a chapter on sugar addiction. Section three contains an exhaustive review of the influence of dietary salt and its diverse mechanistic aspects, including salt-sensitive hypertension, contribution of two steroid receptor pathways, vascular NO, intrarenal RAAS system and angiotensin. The fourth section highlights the biochemistry of dietary saturated, polyunsaturated and trans fat and its influence on human health and various diseases, and further explores NAFLD and gender specific problems. Chapters in this section also investigate the benefits of the Mediterranean diet as well as myths related to cholesterol. Collected and carefully organized for researchers in nutrition, physiology, epidemiology, or sensory science, this book will also benefit general practitioners, surgeons, nurses, health professionals and practitioners, and students studying the role of diet in cardiometabolic disorders and disease.

    • Comparative Kinesiology of the Human Body

      • 1st Edition
      • March 17, 2020
      • Salih Angin + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 1 6 2 7
      • eBook
        9 7 8 0 1 2 8 1 2 2 4 0 2
      Comparative Kinesiology of the Human Body: Normal and Pathological Conditions covers changes in musculoskeletal, neurological and cardiopulmonary systems that, when combined, are the three pillars of human movement. It examines the causes, processes, consequences and contexts of physical activity from different perspectives and life stages, from early childhood to the elderly. The book explains how purposeful movement of the human body is affected by pathological conditions related to any of these major systems. Coverage also includes external and internal factors that affect human growth patterns and development throughout the lifespan (embryo, child, adult and geriatrics). This book is the perfect reference for researchers in kinesiology, but it is also ideal for clinicians and students involved in rehabilitation practice.

    • Aquaculture

      • 1st Edition
      • Volume 38
      • December 1, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 2 0 7 9 4 9
      • eBook
        9 7 8 0 1 2 8 2 2 6 5 6 8
      Approx.364 pages

    • Ayurvedic Perspectives in Integrative Healthcare

      • 1st Edition
      • August 13, 2020
      • Anika Niambi Al-Shura
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 6 0 2 3
      • eBook
        9 7 8 0 1 2 8 1 7 6 0 3 0
      Ayurveda Perspectives in Integrated Healthcare, volume eight in the Integrative Cardiovascular Chinese Medicine series, provides a clear, structured base of knowledge which compares Ayurveda with other healthcare systems to encourage acceptance of Ayurveda in the community and within patient care practices. Sections cover the Shad Darshan, body constitution, medical aspects in Ayurvedic medicine, and the connection between material and spiritual aspects and methods for balancing lifestyle for optimal health. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage new collaboration.

    • An Introduction to Healthcare Informatics

      • 1st Edition
      • July 29, 2020
      • Peter Mccaffrey
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 9 1 5 7
      • eBook
        9 7 8 0 1 2 8 1 4 9 1 6 4
      An Introduction to Healthcare Informatics: Building Data-Driven Tools bridges the gap between the current healthcare IT landscape and cutting edge technologies in data science, cloud infrastructure, application development and even artificial intelligence. Information technology encompasses several rapidly evolving areas, however healthcare as a field suffers from a relatively archaic technology landscape and a lack of curriculum to effectively train its millions of practitioners in the skills they need to utilize data and related tools. The book discusses topics such as data access, data analysis, big data current landscape and application architecture. Additionally, it encompasses a discussion on the future developments in the field. This book provides physicians, nurses and health scientists with the concepts and skills necessary to work with analysts and IT professionals and even perform analysis and application architecture themselves.

    • Epigenetics Methods

      • 1st Edition
      • Volume 18
      • July 2, 2020
      • Trygve O. Tollefsbol
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 4 1 4 0
      • eBook
        9 7 8 0 1 2 8 1 9 4 1 5 7
      In recent years, the field of epigenetics has grown significantly, driving new understanding of human developmental processes and disease expression, as well as advances in diagnostics and therapeutics. As the field of epigenetics continues to grow, methods and technologies have multiplied, resulting in a wide range of approaches and tools researchers might employ. Epigenetics Methods offers comprehensive instruction in methods, protocols, and experimental approaches applied in field of epigenetics. Here, across thirty-five chapters, specialists offer step-by-step overviews of methods used to study various epigenetic mechanisms, as employed in basic and translational research. Leading the reader from fundamental to more advanced methods, the book begins with thorough instruction in DNA methylation techniques and gene or locus-specific methylation analyses, followed by histone modification methods, chromatin evaluation, enzyme analyses of histone methylation, and studies of non-coding RNAs as epigenetic modulators. Recently developed techniques and technologies discussed include single-cell epigenomics, epigenetic editing, computational epigenetics, systems biology epigenetic methods, and forensic epigenetic approaches. Epigenetics methods currently in-development, and their implication for future research, are also considered in-depth. In addition, as with the wider life sciences, reproducibility across experiments, labs, and subdisciplines is a growing issue for epigenetics researchers. This volume provides consensus-driven methods instruction and overviews. Tollefsbol and contributing authors survey the range of existing methods; identify best practices, common themes, and challenges; and bring unity of approach to a diverse and ever-evolving field.

    • Cancer-Leading Proteases

      • 1st Edition
      • January 9, 2020
      • Satya Prakash Gupta
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 1 6 8 3
      • eBook
        9 7 8 0 1 2 8 1 8 1 6 9 0
      Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases.

    • Tumor Immunology and Immunotherapy - Cellular Methods Part B

      • 1st Edition
      • Volume 632
      • January 28, 2020
      • English
      • Hardback
        9 7 8 0 1 2 8 1 8 6 7 5 6
      • eBook
        9 7 8 0 1 2 8 1 8 6 7 6 3
      Tumor Immunology and Immunotherapy – Cellular Methods Part B, Volume 632, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered include Quantitation of calreticulin exposure associated with immunogenic cell death, Side-by-side comparisons of flow cytometry and immunohistochemistry for detection of calreticulin exposure in the course of immunogenic cell death, Quantitative determination of phagocytosis by bone marrow-derived dendritic cells via imaging flow cytometry, Cytofluorometric assessment of dendritic cell-mediated uptake of cancer cell apoptotic bodies, Methods to assess DC-dependent priming of T cell responses by dying cells, and more.

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