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Elsevier

Books in Life sciences

  • Molecular Mechanisms of Cytokine and Growth Factor Receptors

    • 1st Edition
    • Volume 751
    • English

  • The Evolution of Artificial Intelligence in Healthcare

    From Basic Methods to Clinical Practice
    • 1st Edition
    • Mario Cannataro
    • English
    The Evolution of Artificial Intelligence in Healthcare: From Basic Methods to Clinical Practice explores revolutionary technological advancements in the medical and healthcare realms due to generative AI and Deep Learning. This comprehensive guide not only explores cutting-edge technologies such as transformers and large language models for newcomers but also demystifies advanced applications like sequential decoding techniques and segmentation algorithms rarely explored in other literature. Sections cover foundational concepts and terminologies, explore deep learning and generative AI, provide AI's role in biomedical research, examine its integration into clinical practice, scrutinize its applications in public health, and discuss challenges and future prospects.This is an indispensable resource for healthcare professionals, scientists, researchers, students, and enthusiasts seeking to deepen their understanding of this rapidly evolving field.

  • Plant Tissue Culture

    Techniques and Experiments
    • 5th Edition
    • Sunghun Park
    • English
    Plant Tissue Culture, Fifth Edition offers a practice-driven introduction to one of the most influential experimental platforms in plant science. Combining established methodologies with contemporary advances in biotechnology, it demonstrates how cultured cells, tissues, and organs can be used to explore plant development and morphogenesis, propagate valuable germplasm, generate novel variation, and support crop trait enhancement.Structur... around a series of laboratory exercises, the book enables technical proficiency alongside an in-depth understanding of the biological principles that govern cellular growth, function, and regenerative responses. Readers are guided through the investigative techniques that have shaped the field, from micropropagation and embryo rescue to protoplast technologies and plant transformation, illustrating how in-vitro systems continue to serve as powerful tools for both discovery and application.This fully revised edition also discusses the expanding relationship between culture-based methods and molecular approaches, including genome editing and RNA interference. Building on decades of established principles and placing cutting-edge developments in the broader context of plant research and agricultural innovation, the volume highlights the continuing evolution of a discipline that remains central to unlocking and harnessing plant potential.

  • Urinary Incontinence

    Integrating Science and Clinical Practice
    • 1st Edition
    • Marcus Drake + 2 more
    • English
    Urinary Incontinence: Integrating Science and Clinical Practice succinctly describes the importance of lower urinary tract physiology to all for an understanding of urinary incontinence and its clinical treatment. World-leading contributors describe the key influences on mechanisms and therapies for proper understanding of the scientific basis of incontinence.The first part of the book is dedicated to System Physiology: Function and Adaptation. In this section, an anatomical sequence is followed for presenting the chapters, moving from the lower urinary tract organs upwards through the spinal centers to the brain. These chapters discuss what is known and unknown for crucial areas, such as neurological control and co-ordination, bladder fibrosis, bladder physiology and more.The second part is dedicated to Incontinence: Mechanism and Therapy. In this clinical application section, chapters derive from the clinical classification of incontinence and explore topics such as the role of urodynamics; mechanisms underpinning medical and interventional treatments; the sensations arising from the lower urinary tract; adverse effects of therapy and the considerable faced in managing incontinence.Written for researchers and clinicians, this book is a welcomed resource for those aiming to understand more about urinary incontinence.

  • Trauma During Pregnancy

    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Surgical Care of the Critically Ill During Pregnancy, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women in all surgical aspects including trauma. The book's authors offer best practices and evidence-based material explicitly focused on the most common complications in pregnant patients that may occur to improve patient care. It not only covers critical care investigation from medical-surgical complications that any patient can present, but also how to prepare and anticipate complications in the critical care unit.

  • Twin-to-Twin Transfusion Syndrome (TTTS)

    • 1st Edition
    • Michael W. Bebbington + 1 more
    • English
    Twin-to-Twin Transfusion Syndrome (TTTS) is a novel and comprehensive reference to understanding the pathophysiology of this condition, along with the latest diagnostic techniques and criteria for accurate identification, its treatment and management, and strategies for effective management and care. Beyond medical aspects, the book addresses the emotional and practical aspects of TTTS, offering guidance on patient/family support and coping strategies. It includes the latest guidelines and evidence-based practices for TTTS, helping clinicians stay current with advancements in the field and ensuring they adhere to the best standards of care.In addition, the book offers real-world case studies and practical guidance to enable clinicians to effectively apply their knowledge in clinical settings, enhancing their ability to diagnose and manage TTTS cases. Written by various experts in the field, this multidisciplinary perspective fosters collaboration and enables anyone involved in this field to make informed decisions in complex TTTS cases.

  • Biofeedback and Pain Management

    A Clinical Guide
    • 1st Edition
    • Anu Kotay
    • English
    Biofeedback and Pain Management: A Clinical Guide provides a detailed understanding of the psychophysiology of chronic pain, biofeedback treatments, the realities of living life with chronic pain limitations, and the role of pain in our lives and society. The book covers evidence on the effective uses of biofeedback interventions for pain management, including protocols, as well as case-based examples and strategies practitioners can use in real-life settings. Sections define biofeedback, including illustrations that depict how biofeedback is a useful part of any pain management treatment plan, cover procedures based on evidence and case examples, and present the social context of chronic pain.

  • Childhood Disorders of Rickets and Osteomalacia

    A Comprehensive Review
    • 1st Edition
    • Suma Uday
    • English
    Childhood Disorders of Rickets: A Comprehensive Review defines the pathophysiology of rickets and the various genetic and acquired conditions that present with rickets in childhood. This comprehensive review details the various forms of rickets, the histopathology, recent advances leading to new therapeutic options in treating rickets, and the role of Vitamin D and calcium in nutritional rickets. Additionally, the authors explore future research in various areas of nutritional and non-nutritional forms of rickets.Written by global experts for clinicians and researchers treating and studying the various forms of rickets, the book will also be of interest to those working in public health and policy makers working on the prevention of nutritional rickets worldwide.

  • Biopolymer-Based Therapeutics for Inflammation Modulation in Wound Care

    • 1st Edition
    • Neha Raina + 2 more
    • English
    Biopolymer-Based Therapeutics for Inflammation Modulation in Wound Care presents a comprehensive, biomarker-driven exploration of how natural and engineered biopolymers are transforming the management of acute, chronic, and non-healing wounds. Positioned at the intersection of biomaterials science, pharmaceutical innovation, and clinical practice, the book addresses one of the central challenges in wound care: persistent inflammation that delays tissue repair and regeneration. Beginning with the biological and clinical foundations of wound healing, the book systematically examines inflammatory pathways and key biomarkers such as TNF-α, IL-6, ROS, and VEGF.It then advances into in-depth coverage of natural biopolymers—includin... collagen, chitosan, hyaluronic acid, silk-derived polymers, and marine polysaccharides—and their roles in immune modulation, macrophage polarization, and redox balance. Dedicated sections explore advanced delivery platforms such as nanofibers, smart hydrogels, nanozymes, and stimuli-responsive dressings, alongside emerging precision technologies including 3D printing and AI-guided material design. With a strong translational focus, the book bridges laboratory research and real-world application, addressing regulatory pathways, manufacturing scalability, and commercialization challenges.

  • Nanotechnology in Brain Tumor Treatment

    Unveiling Molecular Mechanisms and Pioneering Therapies
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nanobiotechnology in Brain Tumor Treatment: Unveiling Molecular Mechanisms and Pioneering Therapies is a groundbreaking resource that addresses the formidable challenges posed by brain tumors in oncology. This comprehensive book explores the etiology, symptoms, diagnosis, and treatment options for brain tumors, with a particular focus on the revolutionary impact of nanobiotechnology. By integrating cutting-edge research on nanotechnology with practical applications in neuro-oncology, this book offers a unique perspective on enhancing patient outcomes and advancing brain cancer treatment strategies.By offering a comprehensive overview of nanobiotechnology in brain tumor treatment, this resource serves as a vital tool for those involved in the research, diagnosis, and treatment of brain cancers, paving the way for innovative and personalized therapeutic approaches.

  • Current Advances in Cancer Stem Cells and Neoplasia Research

    • 1st Edition
    • Volume 8
    • Hirendra Banerjee
    • English
    Cancer, Volume 8 in the Stem Cell Innovation in Health and Disease series explores the rapidly evolving role of stem cells in cancer treatment. As cancer continues to impose a heavy global health burden, stem cell therapies are being recognized for their regenerative potential and ability to enhance recovery following aggressive therapies. Hematopoietic stem cell (HSC) transplantation is already a standard, FDA-approved treatment for hematologic cancers such as leukemia, myeloma, and lymphoma. These cells help regenerate healthy blood cells post-treatment. In addition, mesenchymal stem cells (MSCs) and neural stem cells (NSCs) are showing promise in preclinical models as therapeutic carriers, capable of homing to tumor sites and delivering anti-cancer agents such as nanoparticles, siRNAs, and small-molecule drugs. Recent clinical advancements include differentiation therapy, where stem cells are used to induce cancer cells to become non-cancerous. Two completed phase I clinical trials have demonstrated innovative applications: one using NSCs to convert a prodrug into a toxic compound within tumors, and another using MSCs engineered with viral enzymes to activate cytotoxic drugs directly at the tumor site. MSCs have also helped reduce graft-versus-host disease (GVHD), a major complication of stem cell transplants. This volume is divided into two main sections: understanding stem cell roles in cancer biology, and translating stem cell innovations into clinical practice. It features cutting-edge research, including organoid models, genetic editing, and iPSC technologies. Together, these insights offer a timely review of the field’s progress and its real-world potential to reshape cancer therapy.

  • Emergent Nanotherapeutics in Diabetic Complications

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Emergent Nanotherapeutics in Diabetic Complications explores how cutting-edge nanotechnology is transforming the treatment of diabetes-related disorders beyond glycemic control. This comprehensive volume examines targeted, multifunctional nanoplatforms designed to address the wide range of comorbidities linked to diabetes, including vascular complications, metabolic dysfunctions, and impaired wound healing. Structured in five parts, the book spans from current nanoformulation strategies to emerging innovations such as CRISPR-Cas9 delivery, AI-guided nanoparticles, and 3D/4D printed nanostructures.Bridg... the gap between preclinical research and clinical application, it offers valuable guidance on stimuli-responsive systems, biocompatible materials, and regulatory pathways. This is essential resource for medical professionals, biomedical engineers, and pharmaceutical scientists seeking scalable, next-generation solutions for managing diabetic complications through nanomedicine.

  • Molecular Chaperones in Neurodegenerative Diseases

    • 1st Edition
    • Volume 156
    • English
    Molecular Chaperones in Neurodegenerative Diseases explores the roles of molecular chaperones in maintaining protein homeostasis and their involvement in the onset and progression of neurodegenerative disorders. The book highlights current research on chaperone-mediated mechanisms, disease pathology, and emerging therapeutic approaches targeting protein misfolding and aggregation.

  • Lightweight Secure and Intelligent Approaches for Medical Devices

    Trends and Future Frontiers
    • 1st Edition
    • R. Praveen + 1 more
    • English
    Lightweight Secure and Intelligent Approaches for Medical Devices: Trends and Future Frontiers addresses the rapidly evolving intersection of artificial intelligence, Internet of Medical Things (IoMT), and edge computing within healthcare. This reference meets the critical demand for resource-efficient, secure, and trustworthy AI models tailored specifically for embedded medical devices operating under stringent constraints. By integrating advances in lightweight AI, medical device security, and intelligent data processing, the book fills a vital gap in current literature, offering researchers, engineers, and healthcare professionals a comprehensive resource to develop next-generation medical technologies. The book is organized into four parts, beginning with foundational concepts including the evolution of AI in healthcare devices, lightweight model design, and medical device security standards. It progresses to predictive intelligence and reliability, covering AI techniques for disease monitoring, device calibration, and personalized medicine. The security and privacy section explores network architectures, privacy-preserving AI, lightweight cryptography, and defenses against adversarial attacks. The final part presents emerging trends such as edge AI, digital twins, explainable AI, augmented and virtual reality applications, and quantum-safe security protocols. Each chapter combines theoretical insights with practical case studies and research perspectives to guide real-world deployment. Lightweight Secure and Intelligent Approaches for Medical Devices: Trends and Future Frontiers serves as an essential reference for researchers, medical device developers, cybersecurity professionals, and graduate students aiming to innovate secure and intelligent healthcare solutions in resource-constrained environments.

  • Application of Python in the Healthcare Technology

    Medical Data Analysis and Developing ML/AI Models
    • 1st Edition
    • Praveen Kumar M
    • English
    Application of Python in Healthcare Technology: Medical Data Analysis and Developing ML/AI Models provides comprehensive coverage of the Python programming language from a medical-based perspective. With a strong focus on utility-based learning rather than technical-based learning of Python, this title clarifies how the application of Python in the healthcare technology industry has a meaningful impact on patient care through the development of deep learning models for early prediction of diseases and the development of Clinical Decision Support System (CDS). In 13 chapters, an extensive range of topics pertaining to the intersection of Python and medical sciences is covered. Coverage defines how to set up an environment to work with python, describes Python class, methods, and functions, explains both basic and advanced statistical analysis in Python, and provides a tool to assist in the development of deep learning models such as API, Git, Github, NumPy, Pandas, and SciPy.

  • The Brain Histaminergic System in Health and Disease

    • 1st Edition
    • Zhong Chen + 2 more
    • English
    Histamines in Neurology and Psychiatry summarizes histamines and their impact on neuroinflammation and brain development in key neural circuits. This book presents the latest research on the physiological regulation of a neuroendocrine responses and releases, broadly discussing histamine receptor modulators and histamine effects in neurology and psychiatry, and also including clinical applications that will be of interest to practitioners.

  • Metagenomics in Biotechnology

    Environmental, Industrial, and Clinical Applications
    • 1st Edition
    • Abd El-Latif Hesham + 3 more
    • English
    Metagenomics in Biotechnology: Environmental, Industrial, and Clinical Applications provides a comprehensive understanding of metagenomic biotechnology, including its underlying principles, techniques, and tools used for data analysis. It explores how metagenomics plays a crucial role in environmental and industrial applications, such as the identification and quantification of microbial communities, the bioremediation of pollutants, biofuel development, and sustainable agriculture. The book also delves into the clinical implications of metagenomics, from technological advancements, pathogen identification, detection, drug discovery, and development. This understanding helps aid in the design and implementation of innovative solutions to environmental, industrial, and clinical challenges. With current trends, challenges, and solutions in metagenomics rounding out the coverage, this book is a valuable resource for researchers, students, and professionals looking to deepen their knowledge of the various techniques used for data analysis and further leverage the potential of metagenomic biotechnology.

  • The Zebrafish Model of Neurodegenerative Disorders

    Knowing the Unknown
    • 1st Edition
    • Wael Mohamed
    • English
    The Zebrafish Model of Neurodegenerative Disorders: Knowing the Unknown reveals a ground-breaking method for decoding neurodegenerative disorders such as Parkinson's, Alzheimer's, ALS, and Huntington's through the lens of the zebrafish. This volume bridges the divide between fundamental science and clinical innovation, demonstrating how the genetic malleability, transparent embryos, and conserved neural pathways of zebrafish provide unparalleled insights into neurodegeneration. It illustrates the potential to uncover concealed pathological mechanisms, expedite drug discovery, and surmount the translational failings that impede current research using this gold-standard model species. Featuring contributions from global experts, this volume is systematically structured into five topical sections for ease of navigation. These sections explore the role of cutting-edge tools such as CRISPR-Cas9, AI-driven phenotyping, and high-throughput drug screening in the study of α-synuclein aggregation in Parkinson's Disease and amyloid-β toxicity in Alzheimer's Disease. The volume offers real-world applications, comparative analyses of zebrafish and mammalian models, and actionable protocols that translate zebrafish discoveries to clinical trials. The Zebrafish Model of Neurodegenerative Disorders is designed to empower researchers, clinicians, and healthcare professionals by addressing existing gaps in knowledge, particularly fragmentation in protocols and the translational disconnect between preclinical models and human trials. By fostering an integrated understanding of zebrafish as a model for neurodegeneration, it enhances research reproducibility, accelerates drug discovery, and promotes ethical, scalable research practices. Whether used as a teaching resource or a reference for experimental design, this volume offers invaluable insights to advance the understanding and treatment of devastating neurodegenerative diseases.

  • Laboratory Sleep Medicine

    Fundamentals of Sleep Technology
    • 1st Edition
    • Ravi Gupta + 2 more
    • English
    Laboratory Sleep Medicine: Fundamentals of Sleep Technology, is the second of the Fundamentals of Sleep Technology series, discusses balancing the fundamentals of sleep medicine with the newest innovations in the lab. High priority is given to practices that must be followed in sleep labs to guarantee the safety of patients and workers. To make information straightforward and easy to grasp, key events in each epoch of polysomnography are showcased. This serves to walk sleep professionals cogently through the history of sleep technology advancement.Laborato... Sleep Medicine: Fundamentals of Sleep Technology is keenly aware that manual titration with PAP is the gold standard treatment for sleep apnea. However, certain patients may require oxygen treatment, which is also covered in depth. In addition, case vignettes illustrate the development of a relevant report using the following: data from a sleep diary, actigraphy, and polysomnography. How to do sleep tests in unusual situations (such as at-home sleep apnea testing and testing in an intensive care unit) are also covered.

  • An Essential Guide to Radiation Dosimetry for Medical Applications

    Principles, Technologies, and Clinical Applications
    • 1st Edition
    • Jayachandran Venkatesan + 1 more
    • English
    An Essential Guide to Radiation Dosimetry for Medical Applications: Principles, Technologies, and Clinical Applications provides a comprehensive overview of the fundamental concepts, advanced methodologies, and emerging technologies in radiation dosimetry. This book serves as an essential resource for researchers, clinicians, and students involved in cancer research, bioinformatics, medical physics, radiology, material scientists and radiation therapy, offering in-depth insights into both theoretical principles and practical applications. The content covers core topics such as radiation interactions, dosimetry materials, and simulation techniques, alongside clinical and diagnostic applications.In addition, it also explores innovative approaches like artificial intelligence, nanodosimetry, and quality assurance, ensuring readers stay current with technological advancements. This book benefits the academic audience by enhancing their knowledge of dosimetry science and fostering the development of safer, more effective radiation practices. It supports education, research, and clinical decision-making, ultimately advancing the field of radiation physics and improving patient outcomes.

  • Advanced Nanofiber Technology in Cancer Management

    • 1st Edition
    • Goutam Rath + 2 more
    • English
    Advanced Nanofiber Technology in Cancer Management presents a comprehensive exploration of nanofiber-based systems for cancer therapy and diagnostics. It bridges pharmaceutical sciences, nanotechnology, and oncology to address the challenges of targeted drug delivery and systemic toxicity. The book covers biopolymer, peptide, carbon, and metal nanofibers, detailing their fabrication, characterization, and application in chemotherapy, immunotherapy, gene therapy, and photothermal treatment. It also explores diagnostic innovations such as biosensors and imaging-guided systems, alongside AI and 3D printing in nanofiber development. This volume benefits researchers, clinicians, and pharmaceutical developers by offering translational insights, regulatory perspectives, and real-world case studies. It supports informed decision-making in cancer management and product development.

  • Operative Strategies in Pelvic Exenteration Surgery

    • 1st Edition
    • Michael E Kelly + 1 more
    • English
    Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part B

    • 1st Edition
    • Volume 193
    • English
    Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part B, published as Volume 193 of the serial International Review of Neurobiology, provides a comprehensive examination of emerging blood-based biomarkers and related biological mechanisms relevant to Alzheimer's disease, Parkinson's disease, vascular cognitive impairment, stroke, and other neuropsychiatric disorders. The volume highlights advances in biomarker discovery, genetic and epigenetic determinants of neurodegeneration, extracellular vesicles and exosomes, protein misfolding, microRNA dysregulation, blood-brain barrier dysfunction, and biofluid-based biosensing technologies. It also explores the integration of artificial intelligence with multimodal biomarker datasets to improve diagnosis, prognosis, and precision medicine approaches. Bringing together contributions from international experts, this volume offers researchers and clinicians an up-to-date resource on translational developments that are shaping the future of neurodegenerative disease detection and management.

  • Lifestyle Medicine

    Lifestyle, the Environment and Preventive Medicine in Health and Disease
    • 4th Edition
    • Michael Sagner
    • English
    Lifestyle Medicine: Lifestyle, the Environment and Preventive Medicine in Health and Disease, Fourth Edition aims to reduce the burden of chronic diseases by harnessing technology and providing a better understanding of environment-biology interactions, evidence-based interventions, and the underlying mechanisms of chronic diseases. This new edition is greatly expanded to cover major chronic diseases as well as infectious diseases. Led by top experts in the field, the editors provide a framework to promote and facilitate multi-stakeholder collaboration with an orchestrated common language and an integrated care model to increase the population’s heath span.The book provides the latest research updates on the pathophysiology of preventable diseases, Clinical updates on interventions for practice, and Public health updates on Precision Medicine / Systems Biology approaches to prevention for clinicians and Interdisciplinary aspects for allied health professionals. It is essential to healthcare professionals who want to: understand the potential of preventing diseases; understand how to maintain health and well-being; understand the implications of preventable diseases for society and individuals; and understand lifestyle aspects in the prevention and treatment of diseases.

  • Capsule Endoscopy in Pediatric Patients from Theory to Practice

    • 1st Edition
    • Thomas M. Attard
    • English
    Capsule Endoscopy in Pediatric Patients from Theory to Practice is a practical and authoritative guide that empowers pediatric gastroenterologists, physicians, and trainees to navigate the complexities of Video Capsule Endoscopy (VCE) in children. With a focus on bridging knowledge gaps and providing practical insights, this book offers updated information on understanding and utilizing VCE in the pediatric population. The book covers the background and technical aspects of VCE, including guidance on setting up a pediatric VCE service and an overview of indications and limitations. It delves into practical aspects such as preprocedural preparation, artifact reduction techniques, and management of capsule retention. By exploring VCE in various disease conditions such as inflammatory bowel disease, gastrointestinal bleeding, hereditary polyposis syndromes, and chronic abdominal pain, readers gain a comprehensive understanding of diagnosis, surveillance, and management. Special content elements, including key terms, case studies, and a timeline of recent advances, enhance the learning experience. This essential resource empowers readers to optimize patient care, make informed decisions, and confidently navigate the realm of VCE in children.

  • Fetal Metabolic Programming in Obesity and Diabetes

    From Mechanisms to Preventive Therapy
    • 1st Edition
    • Luis Sobrevia
    • English
    Fetal Metabolic Programming in Obesity and Diabetes: From Mechanisms to Preventive Therapy describes the consequences of cellular and molecular aspects of maternal obesity (before and during pregnancy), diabetes mellitus (pregestational and gestational), and gestational diabesity (i.e., women with pre-pregnancy obesity that developed GDM). The book covers the clinical aspects of mothers and children and the protocols for treating these diseases during pregnancy. Since the patients' clinical information correlates with metabolic parameters at a cellular and systemic level, it covers several pieces of evidence, addressing the pathophysiology of obesity and diabetes in pregnancy. This is an important resource for health professionals, researchers, and postdocs in obesity diabetes, as well as public health, physiology, biochemistry, cell biology, cell physiology, cell metabolism, and clinical and translational medicine.

  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.

  • Current Research on Biofilm Mediated Chronic Diseases

    Immunological Background and Clinical Interpretations
    • 1st Edition
    • Dibyajit Lahiri + 3 more
    • English
    Current Research on Biofilm Mediated Chronic Diseases: Immunological Background and Clinical Interpretations is an in-depth exploration of the complex interplay between biofilms, the immune system, and chronic diseases. These microbial communities, encased in self-produced extracellular polymeric substances (EPS), adhere to surfaces and resist environmental stresses, including host immune responses and antimicrobial agents.This comprehensive book investigates the formation, characteristics, and profound impact of biofilms on human health. Coverage spans the fundamentals of biofilm formation, immune evasion, and antimicrobial resistance (AMR); the role of biofilms in chronic diseases including periodontal disease, chronic wounds, and respiratory and urinary tract infections; their involvement in cancer development and neural disorders via the gut-brain axis; emerging therapeutic strategies such as nanotechnology, phage therapy, and immunomodulatory approaches; and the growing application of artificial intelligence (AI) and machine learning to biofilm-immune interactions and personalized medicine.Current Research on Biofilm Mediated Chronic Diseases: Immunological Background and Clinical Interpretations provides essential insights for researchers, undergraduates, and postgraduates seeking to understand and combat the challenges posed by biofilms in chronic disease pathology. This book offers valuable knowledge on recent techniques for detecting and mitigating antimicrobial resistance (AMR) and biofilm formation, making it an indispensable resource for scientists and clinicians alike.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Adult Hydrocephalus and Disorders of CSF Dynamics

    • 1st Edition
    • Benjamin D. Elder + 1 more
    • English
    Adult Hydrocephalus and Disorders of CSF Dynamics reviews the pathophysiology, evaluation, differential diagnosis, management and treatment of adult hydrocephalus and disorders of cerebrospinal fluid (CSF). The introductory section begins with the anatomy and physiology of the cerebrospinal fluid system, with a review of adult hydrocephalus management, including longitudinal care and management of comorbidities. The following technical section devoted to shunt design and development, and then management of patients with idiopathic normal pressure hydrocephalus (iNPH). Coverage includes differential diagnosis and treatment of iNPH, as well as common presentations, neuroimaging, genetic studies, CSF biomarkers, and using artificial intelligence. Confirmatory testing discusses high volume lumbar punctures, lumbar drainage trials, and CSF infusion testing. Medical and surgical treatments are reviewed with expected functional outcomes. A subsequent section discusses secondary normal pressure hydrocephalus, caused by other etiologies such as hemorrhage, tumors, or infection, and covers longstanding overt ventriculomegaly (LOVA), management of adult patients who were shunted as children, and Chiari malformations. The book concludes with high and low pressure CSF dynamics disorders, including idiopathic intracranial hypertension and secondary intracranial hypertension, followed by a review of the medical, surgical, and ophthalmological management of these disorders.

  • Bioinformatics, Computational Biology, and Multi-Omics–Driven Probiotic Design for Gut Microbiome Engineering

    • 1st Edition
    • Naheed Mojgani + 3 more
    • English
    Bioinformatics, Computational Biology, and Multi Omics–Driven Probiotic Design for Gut Microbiome Engineering presents an interdisciplinary framework for applying artificial intelligence to microbiome science, probiotic development, and personalized nutrition. The book integrates bioinformatics, computational biology, and clinical insight to address current challenges in gut microbiome research and translation. The volume covers AI driven microbiome profiling, multi omics integration, computational modeling of host–microbe interactions, and predictive analytics. It progresses from foundational concepts to advanced applications, including AI assisted probiotic design, gut–brain axis research, regulatory considerations, and real world case studies supporting translational and clinical relevance. The book equips bioinformaticians, translational microbiome researchers, and clinician scientists with actionable methodologies, conceptual clarity, and validated examples. It supports evidence based decision making, accelerates translational research, and bridges discovery science with implementation in personalized nutrition and probiotic innovation.

  • Roles of the Cerebellum in Motor Control

    Foundations, Experimental Approaches and Clinical Applications
    • 1st Edition
    • Mario Manto + 2 more
    • English
    Roles of the Cerebellum in Motor Control: Foundations, Experimental Approaches and Clinical Applications is a groundbreaking, comprehensive reference on the intricate relationship between the cerebellum and motor function. Spanning five thorough sections, this book examines experimental approaches, from single neurons to networks, unraveling the mysteries of olivocerebellar somatotopy, motor prediction, and the cellular basis of motor learning. With chapters dedicated to neuroimaging, physiology, and pathophysiology, users will gain insight into the cerebellum's role in conditions such as tremor, dystonia, and Parkinson’s disease.From wearable sensors to digital gait biomarkers, various chapters offer a cutting-edge look at sensor technology and its application in assessing cerebellar function and rehabilitation. The book concludes with a discussion on research and clinical implications, providing a roadmap for translating laboratory findings into effective therapeutic strategies, making it an indispensable resource for researchers, clinicians, and students alike.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • RNA-Binding Proteins Part D

    • 1st Edition
    • Volume 746
    • English
    A central theme of this volume is the dynamic relationship between RNA structure, RNA-binding proteins, and cellular organization. The chapters integrate experimental, computational, biochemical, biophysical, imaging, and systems-level approaches to investigate how RNA–protein interactions regulate RNA processing, translation, localization, stability, phase separation, and cellular stress responses. As Volume 746 of the Methods in Enzymology series, the volume emphasizes the integration of methodological innovation with biological applications, providing researchers with practical approaches to dissect how RNA–protein interactions govern RNA fate and function, biomolecular condensate formation, and stress granule assembly.Overall, this collection highlights the transition of RNA biology from a primarily sequence-centered discipline toward a more dynamic view in which RNA structure, molecular interactions, phase separation, cellular organization, and signaling are intimately connected. It will therefore be a valuable resource for researchers and students seeking both practical methodologies and mechanistic insights into the rapidly expanding field of RNA biology.

  • Legal Issues in Quality for Healthcare Institutions

    • 1st Edition
    • Ramesh Sachdeva
    • English
    Legal Issues in Quality for Healthcare Institutions provides the perspective of practicing physicians, lawyers, and academic legal scholars to comprehensively address the implications for quality of care and patient safety both from a legal, medical, and improvement science standpoint. Hospital administrators, physicians, nurses, researchers, legal scholars, as well as regulatory and compliance officers working in hospitals and acute care facilities will find this to be a helpful resource in understanding and addressing the many facets and issues in the field of medicine and law related to quality and patient safety.

  • Edible Electronics

    Principles, Fundamentals, and Applications in Smart Food Packaging and Biomedical Innovations
    • 1st Edition
    • Arun Kumar Gupta + 1 more
    • English
    Edible Electronics: Principles, Fundamentals, and Applications in Smart Food Packaging and Biomedical Innovations addresses the growing global demand for sustainable technologies and environmentally responsible solutions. Conventional electronic devices often rely on toxic, non-biodegradable materials that contribute significantly to electronic waste, posing environmental and health risks, particularly in developing regions and areas with limited waste management systems. By introducing the concept of edible electronics and emphasizing the use of biocompatible and biodegradable materials, this book highlights innovative approaches to reducing electronic waste and mitigating the effects of environmental degradation. It advocates the adoption of sustainable technological practices that can support the needs of an expanding global population while promoting both human and environmental well-being.The book provides a comprehensive exploration of edible electronic materials, including conductors, dielectrics, and semiconductors, and examines their integration into functional electronic systems. It discusses the development of sensors for both in-body and external applications, along with energy storage and supply systems such as batteries and supercapacitors. In addition, the text covers advanced communication methods, including radio-frequency, intra-body, and optical technologies, demonstrating the broad potential of edible electronics across food packaging, healthcare, and biomedical applications.A detailed overview of fabrication techniques is also presented, including deposition, filming, patterning, printing, and carbonization processes. These methods are examined with an emphasis on ensuring the safety, performance, and reliability of edible electronic systems. Furthermore, the book explores regulatory considerations, safety standards, and environmental impacts associated with the development and deployment of such technologies.

  • Starch-based Edible Films and Coatings in Food Applications

    Innovations, Challenges, and Limitations
    • 1st Edition
    • Seid Reza Falsafi + 2 more
    • English
    Starch-Based Edible Films and Coatings in Food Applications: Innovations, Challenges, and Limitations addresses the urgent need for sustainable packaging solutions in the food industry. This book targets the information needs and daily challenges faced by college and postgraduate students, university scholars, researchers, food scientists, and industry professionals working with starch-based edible films and coatings. It provides a comprehensive overview of the latest innovations, current limitations, and ongoing challenges, supporting both academic research and practical industrial applications. The book is structured into four main sections. Section I covers the production of starch-based edible films, detailing native and modified starches, preparation mechanisms, and factors influencing film properties, as well as active, intelligent, and reinforced films. Section II presents recent applications in preserving fresh produce, animal products, and processed foods. Section III reviews current and advanced analytical techniques for characterizing these films. Section IV examines cutting-edge innovations, including nanotechnology and 3D printing, and discusses existing limitations and future challenges.Starch-Ba... Edible Films and Coatings in Food Applications: Innovations, Challenges, and Limitations is a valuable resource for graduate students, researchers, and food technologists. It offers essential knowledge on manufacturing, properties, safety, and market trends, facilitating the development of innovative and sustainable food packaging solutions.

  • Dry Eye Disease

    A Clinical Handbook
    • 1st Edition
    • James Stuart William Wolffsohn + 2 more
    • English
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.

  • Next-Generation Food Bioactives

    Mechanisms, Technologies, and Translational Applications
    • 1st Edition
    • Karuppusamy Arunachalam + 3 more
    • English
    Next-Generation Food Bioactives: Mechanisms, Technologies, and Translational Applications offers a thorough examination of food-derived bioactive compounds such as polyphenols, flavonoids, polysaccharides, peptides, and saponins, and their significance in health promotion, disease prevention and the development of functional foods and nutraceutical products. Divided into six comprehensive sections, the book covers the fundamental properties of these compounds, advanced extraction and analysis methods, and explores their molecular mechanisms and interactions with the gut microbiome. Next-Generation Food Bioactives: Mechanisms, Technologies, and Translational Applications further discusses challenges related to bioavailability, safety, and regulatory considerations, while highlighting emerging trends such as the integration of artificial intelligence and omics technologies in bioactive discovery and functional food formulation. Designed for researchers, industry scientists, and healthcare professionals, this book provides valuable insights to support innovation and evidence-based development in the field of food bioactives.

  • Sleep Neurology

    • 1st Edition
    • Anne Marie Morse
    • English
    Sleep Neurology explores the intricate relationship between sleep and neurological health, bridging the gap between theoretical knowledge and practical application. This comprehensive reference highlights the role of sleep in overall health and provides an examination of how sleep influences a wide range of neurological disorders. From neurodevelopmental issues to neurodegenerative diseases, this book offers a detailed review of how sleep science can be applied to improve patient outcomes in various neurological conditions. Structured around key neurological topics, the book offers insights into conditions such as epilepsy, stroke, and traumatic brain injury, emphasizing the importance of sleep management in their treatment. Each chapter not only discusses the scientific underpinnings of sleep but also provides tangible strategies for integrating sleep health into primary neurological care.

  • Endoscopic Transoral Surgical Approaches to the Skull Base

    • 1st Edition
    • Nyall London + 2 more
    • English
    Endoscopic Transoral Surgical Approaches to the Skull Base provides the first reference for endoscopic transoral surgical techniques and to improve education and training in endoscopic transoral skull base surgery. These approaches can be challenging; this book solves the problem by providing a collection of information regarding these surgical approaches and a dissection guide. This volume will act as a cadaveric surgical dissection guide to assist those interested in utilizing these surgical techniques

  • Spaceflight Ophthalmology and Medicine

    A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers
    • 1st Edition
    • Ryung Lee + 4 more
    • English
    Spaceflight Ophthalmology and Medicine: A Comprehensive Guide to Ocular Health and Related Systemic Health Risks in Astronauts and Space Travelers provides a comprehensive exploration of ocular health issues faced by astronauts during space missions. The book brings together contributions from leading experts in various fields, addressing the multifaceted risk factors associated with spaceflight and their implications for vision and overall health. Sections examine risk factors for ophthalmic diseases, including the effects of microgravity, space radiation, and oxidative stress, and explore innovative approaches in spaceflight ophthalmology, such as advanced diagnostic techniques and potential treatments for ocular conditions specific to the space environment. This book serves as an essential resource for researchers, clinicians, and space medicine professionals. By offering insights into the latest research and practical applications, it enhances understanding of ocular health in space and promotes the development of effective strategies to ensure astronaut safety and mission success.

  • Sarcoma Immunology and Immunotherapy

    • 1st Edition
    • Joseph Crompton
    • English
    Sarcoma Immunology and Immunotherapy offers a timely and comprehensive review of the rapidly evolving field of sarcoma immunology and immunotherapy. This book serves as an essential resource for healthcare professionals, scientists, and patients, providing insights into the immunologic features of sarcoma and the latest immune-based treatments. Focussing on the recent advances, the book discusses the sarcoma microenvironment and the development of innovative immunotherapies tailored for sarcoma patients. Readers will benefit from a thorough overview of existing knowledge, encompassing foundational concepts in sarcoma immunology, a detailed examination of laboratory research, and a complete summary of ongoing immunotherapy trials. This holistic approach ensures a robust understanding of the current landscape in sarcoma research and treatment. By equipping readers with essential background information and comprehensive reviews, this book fosters a deeper understanding of sarcoma immunology and therapeutic strategies. It empowers healthcare professionals and scientists to stay abreast of critical studies, ultimately enhancing patient care and outcomes in this challenging field.

  • Emerging Technologies in Bioengineering for Oncology

    Fundamentals, Research, and Future Prospects
    • 1st Edition
    • Saikat Das + 2 more
    • English
    Emerging Technologies in Bioengineering for Oncology: Fundamentals, Research, and Future Prospects explores the integration of engineering, biology, and medicine to tackle challenges in developing innovative tools for cancer diagnosis and treatment. This comprehensive resource addresses the evolving landscape of bioengineering in oncology, highlighting the intersection of various disciplines to drive advancements in diagnostic and therapeutic approaches. The book explores a range of cutting-edge technologies such as lab-on-chip devices, wearable biosensors, 3D bioprinting, and targeted nanomedicine, offering promising avenues for enhanced diagnostic precision, treatment effectiveness, and personalized healthcare.Geared towards medical students and professionals, the book provides detailed insights into the latest developments, practical applications, and future research directions in the field. By offering a deep dive into the realm of bioengineering for oncology, it serves as a valuable asset for those seeking to advance cancer care through interdisciplinary collaboration and innovation.

  • Endometriosis and Associated Pain

    Bridging Theory and Practice
    • 1st Edition
    • Chi Chiu Wang
    • English
    Endometriosis and Associated Pain: Bridging Theory and Practice is a comprehensive professional resource comparing Eastern and Western perspectives on endometriosis-relate... pain and co-morbidities. It addresses a significant gap by summarizing clinical, pathological, and social aspects, highlighting strengths and weaknesses in both traditions synthesizing existing evidence. The book targets basic science researchers and clinicians in women’s health, reproductive biology, and pain medicine, providing detailed reviews, recent developments, and future directions. Structured into six sections covering clinical features, pathology assessments, treatments, alternative therapies, and global health guidelines, bringing together extensive expertise in reproductive medicine. This book is a vital, up-to-date reference for professionals seeking a cross-cultural understanding of endometriosis pain management.

  • Recent Advances in Food Enzymes

    Innovations and Applications
    • 1st Edition
    • Vijay Kumar + 3 more
    • English
    Recent Advances in Food Enzymes: Innovations and Applications presents the latest developments in enzyme applications across food science, biotechnology, and biochemistry. This essential resource is designed for researchers and professionals, offering in-depth insights into how food enzymes can optimize processes, enhance product quality, and drive innovation within the food industry. Covering a broad spectrum of topics—from fundamental biochemical concepts and AI-driven enzyme discovery to practical applications in dairy, meat, and beverage production—this book serves as a vital reference for those seeking to leverage enzyme technology for improved efficiency and effectiveness in food product development, nutraceuticals and bioprocessing.In addition to addressing the technical aspects of enzyme application, this book emphasizes sustainability and highlights the role of enzymes in waste management and eco-friendly practices, making it invaluable for sustainability advocates. Case studies, expert insights, and technology advancements equips readers with the knowledge needed to navigate the challenges and opportunities presented by enzyme technologies in today's evolving food landscape.

  • Essentials of Medical Coordination in Complex Humanitarian Emergencies

    • 1st Edition
    • Joanna Kotcher
    • English
    Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies provides a practical overview for health coordinators in assessing, coordinating, and implementing medical and public health responses in disaster and conflict environments. The book aims to achieve this in two parts. Part one covers foundational information such as the role of the coordinator; project assessment and start-up; standards, protocols, and guidelines; project strategy and accountability; and basic epidemiological measurements and tools. Part two goes on to discuss the implementation of programs and services like nutrition, mental health and psychosocial support (MHPSS), management of chronic disease, community health promotion, sexual and reproductive health, health information systems and disease surveillance. A health coordinator in the field is required to quickly assess the needs of a population in a humanitarian emergency, initiate start-up procedures, and coordinate the response over a period of months or longer. The efficiency and effectiveness of this process depends on the experience, knowledge, and skills of the coordinator, Essentials of Public Health and Medical Coordination in Complex Humanitarian Emergencies is a resource for those in the medical, public health, and international humanitarian aid sectors who care about the health of populations at risk and is written by an author who has coordinated emergency response in conflict environments in Kosovo, Central Asia (Tajikistan), Afghanistan, Darfur, Gaza and the OPT, Somaliland, Syria, and Iraq.

  • Heavy Metal Stress Resilience in Plants

    Phytohormones and Nanomaterials Interactions
    • 1st Edition
    • Chandra Shekhar Seth + 3 more
    • English
    Heavy Metal Stress Resilience in Plants: Phytohormones and Nanomaterials Interactions provides comprehensive coverage of recent advancements about heavy metals (HMs) transport and stress, phytoremediation mechanisms, and how phytohormones and nanomaterials effectively mitigate the HMs stress in plants. It addresses the consequences of HM to plants, and presents the various approaches to mitigating those consequences. As the environment is increasingly impacted by human input, both intentionally and unintentionally, plant life of all kinds faces increasing challenges to achieving optimal health and production. This book highlights the responsive changes that have increased the genetic diversity of plants and how those changes affect HMs transport in plants. Other key features of the book are coverage of metal toxicity and detoxification mechanism, biochemical tools toward HMs remediation processes, molecular mechanism for HMs detoxification, and role of ROS metabolism in alleviation of HMs. Edited and authored by leading experts from around the world, the book covers the core aspects of plant physio-biochemical and molecular responses into heavy metals stress. Phytohormones and nanomaterials as well as innovative strategies for augmenting plant growth, development and productivity/quality through intrinsic and extrinsic manipulations are included.

  • Human Reproduction

    From basics to Biotechnology
    • 1st Edition
    • Marc yeste
    • English
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

  • Reasoning

    An Integrative Approach
    • 2nd Edition
    • Daniel Krawczyk
    • English
    Reasoning: An Integrative Approach, Second Edition provides an overview, summary, and synthesis of research approaches to the psychology of reasoning. Representing historical perspectives, state-of-the art research, and coverage of upcoming future directions, this volume offers an integrative approach including research on animal behavior, neuroscience, cognitive psychology, AI, development, medicine, and philosophy. The contents range from animal studies through applied situations, and present historical perspectives, discussion of both animal reasoning and human reasoning to provide a cross-species context, and an examination of human reasoning across the lifespan. Though intended primarily for neuroscientists, the book will provide an interdisciplinary examination of reasoning, synthesizing perspectives from neuroscience, cognitive psychology, animal behavior, development, and philosophy, to provide readers with a well-rounded understanding of what reasoning is, various types of reasoning, and its role in decision making and social interactions. New to this edition is research on the influence of technology throughout the book, as well as a greater emphasis on the way that cultural backgrounds and variations in our exposure to information influence our thinking. This will enhance the scope, relatability, and diversity of the book, making it more applicable to future practices and research.

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