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Elsevier

Books in Life sciences

  • Biosynthesis

    • 1st Edition
    • Volume 749
    • English
    In this volume on Biosynthesis, we focus on “unusual enzyme reactions in natural products biosynthesis”. We used the broadest possible definition of the scope of mechanistic biology and biosynthesis to bring in contributors from diverse scientific areas. The articles presented here survey a broad range of enzyme reactions in natural product biosynthesis. We appreciate the valuable contributions from all the authors, and hope that readers can enjoy and learn a lot from these articles.

  • Research Methods

    Principles in Practice
    • 1st Edition
    • Samy A. Azer
    • English
    Research Methods: Principles in Practice provides undergraduate research students, novice researchers, and instructors with engaging approaches to understanding research and how to apply and use different research methods. The book helps students develop skills in conducting literature searches, reading literature, designing research projects, selecting research methods, collecting data, interpreting findings, and writing research reports. Topics covered include research philosophy; study design; developing research questions; the use of theories in research; research ethics; qualitative, quantitative, and mixed-methods research; social media research; and writing a research report. The book provides practical activities, model answers at the end of each chapter, and further reading, enabling students to gain a deeper understanding of research methods and to master their application.

  • Deep Learning Approaches for Healthcare Data Analysis and Decision Making

    • 1st Edition
    • Ashish Bagwari + 5 more
    • English
    Deep Learning Approaches for Healthcare Data Analysis and Decision Making demystifies complex data-driven technologies, providing a clear framework for integrating advanced analytics into healthcare practices. With a focus on practical applications, the authors present a comprehensive digital transformation methodology that empowers readers to tackle the multifaceted challenges of healthcare data management. By leveraging deep learning techniques, readers will learn to analyze vast datasets, identify critical patterns, and develop predictive models that enhance diagnosis and treatment strategies while ensuring compliance with stringent data regulations. The book also addresses the pressing need for ethical AI practices, emphasizing patient privacy and data security.Real-world case studies illustrate how to implement personalized healthcare solutions and foster interdisciplinary collaboration, breaking down silos in knowledge and practice. Moreover, it explores innovative business models for sustainable AI integration, offering actionable insights for healthcare providers. This resource equips professionals with the tools to drive innovation, improve patient outcomes, and navigate the complexities of digital transformation in healthcare, making it a must-read for anyone at the intersection of technology and healthcare.

  • Artificial Intelligence in Point-of-Care Nanobiosensors Technology

    Enhancing Disease Diagnostics and Improved Healthcare Outcomes
    • 1st Edition
    • Tharmaraj Vairaperumal + 2 more
    • English
    Artificial Intelligence in Point-of-Care Nanobiosensors Technology: Enhancing Disease Diagnostics and Improved Healthcare Outcomes delves into the revolutionary integration of artificial intelligence (AI) with nanobiosensors to elevate point-of-care (POC) diagnostics for both communicable and non-communicable diseases. Readers will find insightful chapters covering topics ranging from foundational AI and machine learning techniques to specific applications in cardiovascular disease, diabetes, cancer, chronic respiratory ailments, and infectious diseases. Each chapter not only highlights recent breakthroughs in nanobiosensors but also emphasizes the pivotal role of AI in enhancing diagnostic accuracy and facilitating personalized health interventions. Additional discussions around regulatory considerations and the future landscape of AI in biomedical research make this an essential read for those navigating this rapidly evolving field. This book primarily targets researchers and professionals engaged in the interdisciplinary realms of AI, nanomaterials, and biomedical sciences. By providing a critical understanding of emerging AI-based diagnostic technologies and their applications in POC settings, this book fosters collaboration across diverse scientific domains.

  • Sustainable Thermal Processing in Food Manufacturing

    Ohmic, Microwave and Induction Technologies
    • 1st Edition
    • Ravi Pandiselvam + 2 more
    • English
    Sustainable Thermal Technologies in Food Processing: Ohmic, Microwave, and Induction Technologies offers an authoritative resource on advanced thermal processing technologies critical for modern food preservation and extraction. Addressing the limitations of conventional thermal methods, this reference explores energy-efficient, high-quality, and environmentally responsible heating techniques. The chapters cover fundamental engineering principles, food safety mechanisms, system design, process control, and digital innovations including AI and IoT integration. Specialized topics include drying, pasteurization, cooking, bioactive compound extraction, thawing, fermentation, and nutritional impacts. The text also presents industrial-scale applications, regulatory frameworks, and future research directions, providing a holistic understanding of these emerging technologies. This book equips industry professionals, academic researchers, and students with critical insights to select, model, and implement sustainable thermal processes. It supports innovation in food manufacturing by delivering comparative evaluations, scale-up challenges, and sustainability assessments, fostering adoption of green technologies for improved food safety, quality, and environmental performance.

  • Encyclopedia of Food Security and Sustainability

    • 2nd Edition
    • Pasquale Ferranti + 1 more
    • English
    Similar to the previous edition, Encyclopedia of Food Security and Sustainability, Second Edition, Three Volume Set focuses on the two topics food security and food sustainability, objectives that food systems are expected to fulfil. The encyclopedia covers (a) descriptions of the different components of food systems (that is, agricultural production of food; storage, processing and marketing of food; and consumption of food with focus on nutrition and health – “from farm to flush”), (b) strategies to reach the goals of food security and sustainability of those food systems, and (c) frame conditions that influence the achievements of the Sustainable Development Goals (such as climate change, conflicts and corona (epidemics)). The 2nd edition of the Encyclopedia of Food Security and Sustainability:What it is: a synopsis of the path society is currently on with respect to securing food for a growing population in the present century.What it concerns: it is a reference work to investigate/discuss the focal issues of sustainable food production for humankind in the coming years, also in relation to the effects of global change on food resources, biodiversity and global food security. It is recognized that the topic involves complex adaptive systems.Its objective: to become a platform to show how integration of different disciplines is necessary to strengthen the existing capacity to generate and share research data through closer collaboration not only within the scientific community, but also within the industrial world and society in general.Its Impact: this collection of methodological approaches and derived knowledge will have impact on the research community, food industry, scientists and students in the way to relate and report on the novel challenges of food productions to secure food to humanity in a sustainable way.

  • Electrochemical Sensors and Biosensors for Food Safety

    Fundamentals, Nanomaterials, and Real-World Applications
    • 1st Edition
    • J. Tharini + 1 more
    • English
    Electrochemical Sensors and Biosensors for Food Safety: Fundamentals, Nanomaterials, and Real-World Applications is a vital resource addressing the urgent need for highly sensitive detection of organic, inorganic, and biological pollutants in food and water. Detecting hazardous molecules at nanomolar levels is crucial for ensuring public health and food safety, yet current methods often lack the sensitivity and specificity required for early detection. This book explores how advanced nanomaterials and flexible substrate matrices enhance the performance of electrochemical sensors, providing accurate, rapid, and cost-effective solutions for detecting contaminants in complex samples. The book covers essential topics, including the fundamentals of electrochemical sensing, nanocomposite synthesis, computational modeling, fabrication of flexible electrodes, and integration with artificial intelligence and IoT technologies. It discusses applications in detecting pesticides, heavy metals, veterinary drugs, food additives, and microbial pathogens, as well as the regulatory frameworks governing their use. Case studies and future directions highlight the potential for developing smart, reusable sensors that can be implemented in real-world food safety monitoring systems.Electrochemi... Sensors and Biosensors for Food Safety: Fundamentals, Nanomaterials, and Real-World Applications serves as an indispensable guide for researchers, industry professionals, and policymakers committed to advancing food safety technologies, protecting public health, and promoting innovative solutions for sustainable food systems.

  • Brain Point-of-Care Ultrasound

    Practical Guide and Protocols
    • 1st Edition
    • Camilo N. Rodríguez + 6 more
    • English
    Brain Point-of-Care Ultrasound: Practical Guide and Protocols explores brain hemodynamics and parenchyma examination, providing an orderly and protocolized approach that facilitates individualized clinical decisions with ease. Covering ultrasound configuration, in-depth anatomical knowledge, and advanced parameters, this guide aims to integrate brain ultrasound seamlessly into the Point-of-Care Ultrasound (POCUS) modality, addressing the critical need for comprehensive patient assessment. From basic principles to specialized clinical situations, each section of this guide is meticulously crafted to empower practitioners with practical insights. Chapters explore Doppler spectral wave interpretation, angle correction nuances, autoregulation dynamics, and non-invasive pressure estimations, among others, thus enabling precise monitoring and targeted decision-making. With a focus on integration across disciplines and specialties, this book bridges the gap between classical pathology and contemporary practice, positioning brain ultrasound as a pivotal tool in the armamentarium of modern critical care.

  • Omics Bioprospecting of Beneficial Microorganisms in Sustainable Agriculture

    • 1st Edition
    • Sergio de los Santos Villalobos + 2 more
    • English
    Advances in high-throughput sequencing, systems biology, and microbiome science reveal unprecedented opportunities to harness microbial diversity for crop productivity, soil health, nutrient management, and pest and disease control. These technologies are enabling researchers to move beyond the simple identification of useful microorganisms toward a mechanistic understanding of their functions, interactions, and uses in agricultural systems.Omics Bioprospecting of Beneficial Microorganisms for Sustainable Agriculture examines how genomic, transcriptomic, proteomic, metabolomic, metagenomic, and integrated multi-omics approaches are accelerating the discovery and development of agricultural biologicals. Chapters cover plant-growth-promoti... and nutrient-solubilizin... bacteria, mycorrhizal and endophytic fungi, insect-associated microorganisms, bacteriophages, and plant-associated viruses, highlighting their roles in supporting plant health and ecosystem resilience.In addition to discovery pipelines, the book addresses emerging tools for community profiling, activity characterization, microbial engineering, and precision agriculture. Real-world applications and case studies demonstrate how these approaches are being translated into reduced reliance on chemical inputs and suited to specific crops and growing conditions.The volume concludes with discussions on biosafety, regulatory frameworks, commercialization challenges, climate resilience, and future directions for microbiome-based innovations. Bringing together perspectives from leading scholars across disciplines, it provides a comprehensive reference for scientists, agronomists, microbiologists, biotechnology professionals, and graduate students committed to strengthening food security.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 137
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Advances in Immunology

    • 1st Edition
    • Volume 172
    • English
    Advances in Immunology, Volume 172, provides current research contributions in immunology, including a detailed examination of gasdermin activation mechanisms and their role in initiating membrane pore formation to execute pyroptosis. Further chapters from an international group of contributors extend the volume's coverage of immune mechanisms and disease relevance.

  • Antimicrobial Resistance in the 21st Century

    Equity, Technology, and One Health Approaches
    • 1st Edition
    • Ajmer Singh Grewal + 4 more
    • English
    Antimicrobial Resistance in the 21st Century: Equity, Technology, and One Health Approaches offers a timely, interdisciplinary exploration of one of the most pressing global health challenges. Moving beyond traditional clinical and microbiological perspectives, this volume integrates equity, digital innovation, and One Health principles into a cohesive framework for understanding and addressing antimicrobial resistance (AMR). It examines how social determinants, economic pressures, and policy environments intersect with biological drivers to shape resistance patterns and outcomes worldwide. Drawing on expertise across pharmacy, medicine, public health, veterinary science, and data science, the book combines foundational knowledge with advanced insights. Real-world case studies and applied examples highlight antimicrobial use in human and animal health, stewardship strategies, infection prevention, and surveillance of both common and neglected diseases. Special attention is given to vulnerable populations, including neonates, children, and marginalized communities, alongside critical discussions of ethics, gender, and global inequities. The integration of artificial intelligence, data analytics, and digital surveillance tools demonstrates how emerging technologies can enhance prediction, monitoring, and decision-making in AMR. By bridging theory, practice, and policy, this book equips readers with the tools to design sustainable, evidence-based interventions. It is an essential resource for researchers, students, and professionals seeking to navigate and address the complex, interconnected dimensions of AMR in a rapidly evolving global landscape.

  • Clinical Brain Stimulation Part A

    • 1st Edition
    • Volume 308
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Decoding Cancer

    Precision Oncology through AI, Machine Learning, and Multi-Omics Analytics
    • 1st Edition
    • Pawan Kumar Maurya + 1 more
    • English
    Decoding Cancer: Precision Oncology through AI, Machine Learning, and Multi-Omics Analytics offers an integrated perspective on how computational technologies are transforming cancer research and care. It bridges cancer biology with advanced data-driven approaches to enable precision oncology. The book covers fundamentals of cancer biology alongside applications of artificial intelligence, machine learning, and big data analytics in biomarker discovery, early detection, and personalized treatment. Chapters explore multi-omics integration, predictive modeling, radiomics, surgical robotics, and ethical considerations, supported by diagrams, case studies, and annotated workflows. For academics and professionals, this resource provides actionable insights into cutting-edge tools and methodologies, helping readers understand how computational oncology accelerates translational research and clinical decision-making. It serves as a comprehensive guide for students, researchers, and clinicians navigating the future of data-driven cancer care.

  • Substance Use Disorders and Behavioral Addictions

    Neurochemical Mechanisms and Clinical Implications
    • 1st Edition
    • Mohammad Shabani + 2 more
    • English
    Substance Use Disorders and Behavioral Addictions: Neurochemical Mechanisms and Clinical Implications offers an in-depth exploration of the neurochemical foundations of addiction, addressing both substance-related and behavioral disorders. This volume is essential for neuroscientists, psychiatrists, and pharmacologists seeking to understand the complex neurobiological pathways involved in addiction. It covers key neurochemical systems such as dopamine, glutamate, serotonin, and endocannabinoids, and examines their roles across a spectrum of disorders including nicotine, opioids, alcohol, stimulants, cannabis, psychedelics, sedatives, caffeine, antihistamines, and behavioral addictions like gambling, gaming, pornography, and binge eating. This content synthesizes cutting-edge preclinical techniques—such as optogenetics and neuroimaging—with clinical models like cue-reactivity and pharmacogenomics, providing a translational perspective that bridges research and practice. The purpose of this book is to fill existing gaps where neurochemical insights are often isolated from clinical application, especially in the context of rising addiction rates globally and emerging treatments like psilocybin and neuromodulation. It aims to equip researchers and clinicians with current, practical knowledge to develop innovative interventions, improve diagnostics, and personalize treatment strategies. Whether used as a reference for research, clinical decision-making, or advanced coursework, this volume offers a vital resource for advancing understanding and management of addiction in diverse settings.

  • The Autism Spectrum

    Identification, Understanding, and Treatment in Global Context
    • 1st Edition
    • Matthew K. Belmonte + 1 more
    • English
    The Autism Spectrum: Identification, Understanding, and Treatment in Global Context provides an update to the basic and clinical sciences of autism with an understanding of how research and clinical treatments are affected by recent shifts of focus: from diagnostic categories to symptomatic dimensions, from provider-centered to patient-centered treatment approaches, from high-resource, individualistic country insights to those contributed from global cultures.This volume discusses the field’s current state, whence it has come, where it is going, and how to get there. The volume weds basic and clinical understandings, state-of-the-art multivariate analyses, historical and cross-cultural information and relevance, and a patient-centered focus.

  • Interstitial Lung Diseases

    New Frontiers in Research and Clinical Applications
    • 1st Edition
    • Carlo Vancheri + 1 more
    • English
    Interstitial Lung Diseases: New Frontiers in Research and Clinical Applications is the book that professionals working with Interstitial Lung Diseases (ILDs) have been waiting for. ILDs encompass a complex group of diseases, characterized by varying degrees of inflammation and fibrosis in the lungs, leading to diverse clinical presentations and subtle differences in imaging findings. This complexity makes diagnosis challenging for pulmonologists, radiologists, and researchers, who must stay updated on evolving pathophysiology, diagnostic innovations, and new classification systems. This comprehensive, invaluable resource integrates the pathogenic, functional, clinical, and radiological aspects of ILDs, providing clinicians with a practical tool for patient care. This book elucidates the distinguishing features of different ILDs, empowering readers to navigate the diagnostic and therapeutic landscape confidently. It offers a practical, step-by-step approach to diagnosing ILDs and understanding their nuances, structured around the latest scientific evidence. Further, it covers etiology, epidemiology, pathogenesis, diagnostic processes, and therapeutic options, incorporating diagnostic and treatment algorithms to serve as both a reference and a practical guide for clinical decision-making. By filling gaps in the literature, “Interstitial Lung Diseases: New Frontiers in Research and Clinical Applications” equips respiratory professionals with the knowledge and skills necessary to enhance diagnostic accuracy, improve patient management, and foster ongoing innovation in the study of ILDs.

  • Epigenetics of Alzheimer's and Parkinson's Disease Part A

    • 1st Edition
    • Volume 118
    • English
    Epigenetics of Alzheimer's and Parkinson's Disease Part A, published as Volume 118 of the serial Advances in Genetics, provides a focused survey of the epigenetic mechanisms underlying two of the most prevalent neurodegenerative disorders. Contributions from international researchers examine microRNA-based therapeutic strategies, exosome-mediated pathways, noncoding RNA regulation, DNA and histone modifications, and gene-environment-epi... interactions in Alzheimer's and Parkinson's disease. The volume offers researchers a current reference point for understanding how epigenetic regulation contributes to disease onset and progression, and how these mechanisms might be targeted therapeutically.

  • Vagus Nerve

    From Homeostatic Regulations to Disease Etiopathogenesis, Treatment, and Prevention
    • 1st Edition
    • Boris Mravec
    • English
    Vagus Nerve: From Homeostatic Regulations to Disease Etiopathogenesis, Treatment, and Prevention is a comprehensive reference that encapsulates every critical aspect of the vagus nerve, tracing its anatomy, phylogeny, and physiology while exploring its pivotal role in both maintaining homeostasis and the development of various diseases. This groundbreaking work details the potential of vagus nerve stimulation as a therapeutic and preventive measure for a wide range of conditions, including neurological, psychiatric, inflammatory, cardiovascular, and gastrointestinal disorders. This book demystifies the mechanisms of vagus nerve function and its implications for health and disease. Each section delves into the historical context of vagus nerve research, its anatomical and functional characteristics, and its regulatory roles across multiple organ systems. Additionally, the book investigates the etiopathogenesis of diseases linked to vagus nerve dysfunction and outlines experimental methods for investigating its functions. With a focus on prognosis and therapy, this book highlights the prognostic value of vagus nerve activity and explores various therapeutic modalities that influence it. Concluding with directions for future research, this essential resource aims to foster a deeper understanding of the vagus nerve's significance in health and disease, opening new avenues for therapeutic innovation and clinical application.

  • Systems Biology of Addiction Medicine

    Gut–Brain Axis, OMICS, and Molecular Technologies
    • 1st Edition
    • Mohammad Shabani + 3 more
    • English
    Systems Biology of Addiction Medicine: Gut–Brain Axis, OMICS, and Molecular Technologies is a cutting-edge reference that explores the complex neurobiological mechanisms underlying substance use disorders (SUD). This volume emphasizes the importance of the microbiome-gut-brain axis (MGBA), multi-OMICS approaches, and molecular tools such as CRISPR-Cas9 in advancing addiction research. It addresses the urgent need for integrated frameworks to understand the bidirectional communication between the gut and brain in disorders like nicotine, opioid, alcohol, neurostimulant, and cannabis use. The book synthesizes foundational knowledge with recent developments, offering detailed methodologies, case studies, and translational strategies that bridge basic science and clinical application. Its comprehensive scope makes it invaluable for researchers and clinicians seeking to develop personalized, evidence-based therapies for SUDs. The contents include dedicated sections on the MGBA's role across various substances, detailed chapters on multi-OMICS, SNP, and immunotherapy techniques, and discussions on emerging molecular technologies like CRISPR. Each chapter combines literature reviews, recent advances, and practical applications, supported by schematic figures designed for clarity. The volume aims to empower neuroscientists, psychiatrists, pharmacologists, and biotech professionals with the latest scientific insights and tools to address the global challenge of addiction. By fostering interdisciplinary understanding, this resource supports hypothesis generation, research innovation, and the development of targeted interventions to improve patient outcomes.

  • Microbiome Profiling, Techniques, and Therapeutic Management

    • 1st Edition
    • Sanjana Mehrotra + 1 more
    • English
    Microbiome and Tumorigenesis: Microbiome Profiling, Techniques, and Therapeutic Management, vol. 2 offers a comprehensive exploration of cutting-edge methodologies and clinical applications in microbiome research. This book focuses on the intersection of microbiome science with cancer therapy, bioinformatics, and environmental influences, making it a valuable resource for researchers, clinicians, and graduate students in biomedical and life sciences. The book is structured into three parts: tools and techniques for microbiome analysis, the role of the microbiome in cancer therapy, and the impact of diet, environment, and epigenetics on microbiome–tumor interactions. Topics include sampling strategies, AI-driven data analysis, microbiome-based biomarkers, and therapeutic interventions, with contributions from experts across academia and industry. This book equips the academic audience with both foundational and advanced insights into microbiome research. It supports interdisciplinary learning, fosters translational thinking, and provides practical knowledge for designing experiments, interpreting data, and developing novel therapeutic strategies.

  • Viticulture and Climate Change

    Challenges and Opportunities
    • 1st Edition
    • Stefano Poni
    • English
    Accelerating atmospheric shifts are redefining grape production worldwide in complex and often unpredictable ways, disrupting long-established practices while opening the door to new possibilities. Viticulture and Climate Change examines how rising temperatures, irregular rainfall patterns, and increasingly frequent extreme events influence cultivation outcomes, including vine seasonal development, berry composition, and overall vineyard performance. It presents a forward-looking panorama that translates scientific insight into applied guidance, enabling the effective implementation of adaptive and sustainable grape-growing practices.Rather than treating individual factors in isolation, the text adopts a whole-system view. The volume is organized to follow the vineyard lifecycle, from establishment through routine operations to long-term planning, with case studies aptly embedded throughout. It addresses variety and rootstock selection, spacing, training systems, soil care, canopy handling, water use, and innovative inputs. Dedicated sections explore frost, heatwaves, drought, flooding, and hail scenarios, alongside appropriate responses such as pruning adjustments, shading solutions, and protective materials. Emerging topics—such as manipulation of ripening dynamics for low- and no-alcohol wines, carbon cycling, and renewable energy integration—are also considered.Advances in sensing, mapping, automation, and modeling are presented within interconnected digital platforms, offering new ways to monitor conditions and guide interventions. Biotic threats from pathogens and insects are discussed in the context of variable climatic pressures, with emphasis on tolerance and robustness-enhancing measures.Drawing on a broad body of research and experience by a leading expert in the field, Viticulture and Climate Change interprets findings with clarity and purpose, transforming technical information into accessible knowledge with practical relevance across diverse regions in support of improved real-world, cost-effective decision-making.

  • Wearable Sensors for Healthcare Monitoring

    Smart Tools for Real-time Applications
    • 1st Edition
    • Pushpesh Ranjan + 1 more
    • English
    Wearable Sensors for Healthcare Monitoring: Smart Tools for Real-time Applications addresses the growing need for advanced diagnostic tools amid increasing global health challenges. The reference explores state-of-the-art wearable biosensors that enable non-invasive, continuous, and real-time monitoring of disease biomarkers in biofluids such as sweat, saliva, and tears. This technology offers promising solutions to overcome limitations of conventional diagnostics, providing sensitive, portable, and user-friendly healthcare management tools. The contents cover fundamental to advanced topics including nanoengineered materials, design and fabrication methods, classifications of biosensors, and detection techniques for various biomarkers. Additional chapters focus on applications in diabetic care, inflammatory biomarker monitoring, wound healing, infectious disease detection, personalized nutrition, and integration with intelligent wireless technologies.The book also addresses self-powered wearable devices and market commercialization prospects, offering a holistic view of the wearable biosensor landscape. This books benefits researchers, academicians, clinicians, diagnostic laboratories, and industry professionals by delivering comprehensive insights into the design, development, and application of wearable biosensors. It serves as a valuable platform for innovation, enabling the creation of high-performance, affordable, and smart diagnostic tools that can transform personalized healthcare and point-of-care monitoring.

  • Advances in Pancreatic Cancer Immunotherapy

    • 1st Edition
    • Vivek P. Chavda + 2 more
    • English
    Advances in Pancreatic Cancer Immunotherapy explores cutting-edge strategies to combat one of the most lethal malignancies. This book provides a focused, comprehensive resource on immunotherapy innovations for pancreatic cancer. It examines the tumor microenvironment, mechanisms of immune evasion, and the latest therapeutic modalities, including immune checkpoint inhibitors, cancer vaccines, and adoptive cell therapies. Chapters cover clinical and preclinical studies, combination strategies, biomarker-driven personalization, and regulatory considerations, offering a deep dive into both foundational science and translational applications. For researchers, clinicians, and graduate students, this book delivers actionable insights into overcoming treatment resistance, integrating immunotherapy into clinical practice, and shaping future research directions. It serves as an essential reference for understanding and applying immunotherapeutic advances to improve patient outcomes.

  • Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine

    • 1st Edition
    • Anthony Chang + 1 more
    • English
    Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. This book vastly improves the speed of adoption of AI in pediatric and neonatal healthcare by providing a framework of AI deployment in children and healthcare. In addition to a large section on the principles and theories of artificial intelligence as well as its application in a number of pediatric subspecialties, the book will have about 50 commentaries that all have the same structure The book is presented in a systematic manner for all clinicians to understand the in-depth thinking of the leaders in the pediatric AI domain from an international perspective. Artificial Intelligence and Clinical Cognition in Pediatric and Neonatal Medicine is an essential guide with an introduction to data science and artificial intelligence to provide the reader with a quick orientation and education on AI in healthcare. It also offers a framework for success in planning, deployment, implementation, and evaluation of AI models in healthcare. In addition, current state of the art of pediatric subspecialties will be presented with future directions to guide the pediatric and neonatal clinicians. Finally, a colorful collection of commentaries by leaders of AI use in children’s health is inserted throughout the book.

  • Decision Neuroscience

    • 2nd Edition
    • Jean-Claude Dreher
    • English
    Decision Neuroscience: An Integrative Perspective, Second Edition, Volume Two presents the most recent and compelling lesional, neuroimaging, electrophysiological... and computational studies in combination with hormonal and genetic studies that have led to a clearer understanding of the neural mechanisms behind reward and decision-making. The neural bases of reward and decision-making processes are of critical interest to scientists because of the fundamental role that reward plays in a number of behavioral processes (such as motivation learning, and cognition), and because the neural bases have theoretical and clinical implications for understanding dysfunctions of the dopaminergic system in several neurological and psychiatric disorders.This book provides a comprehensive update on groundbreaking work that addresses fundamental questions about the nature of behavior, including how does the brain process reward and how does it make decisions when facing multiple options? It features entirely new content, as well as expanded coverage on drug and behavioral addiction and the role of subthalamus stimulation in neurological disorders and neuroeconomics.

  • The Biomechanics of Osseointegration

    • 1st Edition
    • Adriano Piattelli + 1 more
    • English
    The Biomechanics of Osseointegration offers a comprehensive, evidence-based exploration of the biomechanical, anatomical, and biological principles essential to safe and effective use of dental implants. By integrating core sciences with clinical applications, it equips both current and future practitioners with the tools to deliver long-term success in implant therapy. From fundamental concepts such as bone biology and stress-strain relationships to advanced topics like finite element modeling, fatigue testing, and real-world clinical implications, this work bridges the divide between theory and practice. Readers gain deep insight into the biomechanics of standard, short, pterygoid, and zygomatic implants across varying bone types, loading conditions, and anatomical challenges. Examined are long-term histological findings from retrieved human implants, unpacking the reasons behind the success of design elements such as the Cone Morse connection. Grounded in both research and practical examples—including case studies and data spanning three decades—the importance of connecting basic science with clinical expertise is highlighted. Designed primarily for dentists considering the integration of implantology into their practice, as well as postgraduate students in Periodontology, Prosthodontics, Oral Surgery, and Biomedical Engineering, The Biomechanics of Osseointegration also serves as a valuable resource for undergraduate dental and biomechanical engineering students who are entering the field with limited formal education in implant science. With an interdisciplinary approach and emphasis on biomechanics and biology, it provides a critical foundation for anyone committed to advancing in the field of dental implants—ensuring their work is not only innovative but also grounded in safe and effective treatment principles.

  • Microbiome-Drug Interactions in Neurological Disorders: Pharmacological Mechanisms, Targets, and Therapeutic Advances

    • 1st Edition
    • Volume 109
    • English
    Advances in Pharmacology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Solvent Interaction Analysis

    Physical Chemistry and Analytical Applications of Aqueous Two-Phase Systems
    • 1st Edition
    • Boris Y. Zaslavsky + 1 more
    • English
    Solvent Interaction Analysis: Physical Chemistry and Analytical Applications of Aqueous Two-Phase Systems explores Solvent Interaction Analysis (SIA) technology, a cutting-edge approach for protein characterization and proteomics in biological fluids. The book considers a broad spectrum of topics, from fundamental principles such as phase separation, blood-tissue distribution, and posttranslational protein modifications to advanced clinical applications for early detection of various malignancies, neurological disorders, and other diseases. The book opens with an introduction to aqueous two-phase system (ATPS), considering different types of ATPS, hydrophobic and electrostatic properties, and mechanisms of liquid-liquid phase separation, before moving on to specific properties of phases such as solute-water interaction and blood-tissue distribution, and analysis of partitioning individual proteins. It then explores solvent interaction analysis, investigating diagnostic applications and biomarker discovery. Final chapters explore fundamental consequences of ATPS-based analysis and its future opportunities.This comprehensive guide offers a detailed overview of aqueous two-phase systems from foundational knowledge to the latest developments in the field, and is an essential reference for students, researchers and practitioners across a wide range of disciplines, including biophysics, analytical and medicinal chemistry, proteomics, structural biology, pharmaceutical science, and biotechnology.

  • Cold-Adapted Enzymes

    Biochemistry and Biotechnology
    • 1st Edition
    • Diego Gomez-Casati + 1 more
    • English
    Cold-Adapted Enzymes: Biochemistry and Biotechnology provides a cutting-edge investigation into the molecular mechanisms, structural dynamics, and regulatory pathways of enzymes adapted to cold environments.Beyond classical microbiology, the book explores cold adaptation from psychrophilic bacteria and Antarctic fungi to microalgae, plants, and mammalian cell physiology. It provides biochemistry insights into carbohydrate (amylases, glucoamylases) and lipid metabolism, proteases, and redox enzymes, alongside the roles of molecular chaperones and prokaryotic proteomics. A key highlight is its focus on next-generation biotechnology, featuring AI-driven protein design, advanced computational modeling, and structural bioinformatics. Bridging foundational science with market reality, the volume explores applications from organic waste valorization to industrial biocatalysis, analyzing the global patent landscape and commercial players.As the latest volume in the Foundations and Frontiers of Enzymology series, this book is an indispensable reference for researchers across biochemistry, biotechnology, structural biology, and microbiology.

  • Biofabrication Technologies for Tissue and Organ Engineering and Manufacturing

    • 1st Edition
    • Lorenzo Moroni + 1 more
    • English
    Biofabrication Technologies for Tissue and Organ Engineering and Manufacturing is the fourth volume in the Regenerative and Transplant Medicine Series. The book offers a range of benefits tailored to its diverse audience. For students in biomedical engineering and related fields it provides a comprehensive understanding of biofabrication technologies in tissue and organ engineering and preparing them for future careers. Researchers and scientists in tissue engineering benefit from staying current with the latest advancements, fostering interdisciplinary collaboration, and offering practical insights for experimental design. Clinicians and healthcare professionals gain a deeper understanding of biofabrication applications, improving patient care and staying informed about emerging technologies. Industry professionals in medical devices and biofabrication find valuable insights for product development and market opportunities, while educators use the textbook to enrich curricula and provide real-world applications for students. Regulatory affairs specialists benefit from updates on ethical considerations and compliance in biofabrication, and government officials gain insights into shaping policies for responsible innovation.The authorship is intentionally diverse, encompassing professionals from various backgrounds, including gender, ethnicity, and geographical location. The authors explore applications of biofabrication technologies across different cultural and medical contexts, including voices from underrepresented groups in the fields of biomedical engineering and biofabrication.

  • Smart Microscopy, AI, and Robotics

    Automated Future Disease Detection
    • 1st Edition
    • Priyadarshini Pattanaik + 2 more
    • English
    Smart Microscopy, AI, and Robotics: Automated Future Disease Detection addresses the need to combine automated microscopy with artificial intelligence and robotics to improve accuracy, throughput, and safety in disease detection. It surveys methods for image acquisition, processing, segmentation, and interpretation across sample types, including blood smears, tissue biopsies, cytology, and cytopathology, equipping researchers, clinicians, and technologists with actionable knowledge for deploying AI-powered diagnostic pipelines.The book covers foundational principles and advanced applications, beginning with microscopy and contrast-enhanced imaging, followed by automated microscope–robotics integration, image acquisition and analysis pipelines, and AI methods for disease detection. It then explores applications such as blood disorders, infectious diseases, and cancer diagnostics, including AI-based analysis of neurological and cellular imaging, advanced deep-learning architectures, and foundation models for smart microscopy. System-level considerations address performance metrics, explainability, bias mitigation, ethics, clinical governance, regulation, safety, and human–AI interaction and interoperability. The book also examines AI-enabled drug discovery, therapeutic target identification, smart laboratories, automated diagnostics, and global health impact.Readers will gain practical guidance on building high-throughput, AI-assisted diagnostic systems that are robust, interpretable, and scalable, with insights into data annotation, model validation, and integrating AI with robotic microscopy in clinical and research settings. The work anticipates developments such as self-calibrating instruments, autonomous laboratory workflows, and digital pathology ecosystems.

  • Redefining the MicroRNA Functionality in Cancer Diagnostics and Therapeutics

    • 1st Edition
    • Vivek Kumar + 2 more
    • English
    Redefining the MicroRNA Functionality in Cancer Diagnostics and Therapeutics is an authoritative volume that explores the pivotal role of microRNAs (miRNAs) in precision oncology. The book integrates fundamental biology, cutting-edge bioinformatics, and translational research, providing a comprehensive overview of miRNA mechanisms, regulation, and clinical applications. It emphasizes technological advances such as single-cell profiling, CRISPR engineering, and AI-driven diagnostics. The content covers miRNA biology, multi-omics integration, innovative therapeutic strategies, and clinical translation, including liquid biopsies and biosensors.In addition, it also addresses industry and regulatory aspects, offering practical insights for translating research into clinical and commercial settings. Rich with case studies and visual aids, the book bridges the gap between bench research and bedside implementation. For the academic audience, this book offers a multidisciplinary resource that enhances understanding of miRNA-based diagnostics and therapeutics, fostering innovation and accelerating clinical adoption in cancer care.

  • Statistics in Medicine

    • 5th Edition
    • Robert H. Riffenburgh + 1 more
    • English
    Statistics in Medicine, 5th Edition serves as an essential resource for health care students, professionals and researchers seeking to understand the application of statistical methods in medical research. This comprehensive text encompasses a wide range of topics, from foundational concepts to advanced techniques, ensuring that readers are well-equipped to design, analyse, and interpret health-related studies. The book includes updated chapters on critical subjects such as missing data, regression models for discrete outcomes, polytomous response regression, classification and regression trees, and the integration of machine learning and AI with statistical methodologies. Each chapter provides practical examples and step-by-step methods, helping readers understand complex concepts while reinforcing learning through exercises and real-world applications. For the academic audience, this book offers a user-friendly approach to medical statistics, making it accessible even to those with limited statistical training. By bridging the gap between theory and practice, it empowers health care professionals to conduct rigorous research, interpret findings accurately, and contribute meaningfully to advancements in medical science.

  • Flow Cytometry-Based Diagnosis for Inborn Errors of Immunity

    • 1st Edition
    • Reza Yazdani
    • English
    Flow Cytometry-based Diagnosis for Inborn Errors of Immunity addresses the need for a practical, comprehensive reference on applying flow cytometry to the diagnosis, classification, characterization, and prognostic evaluation of inborn errors of immunity (IEI). As flow cytometry becomes central to identifying and characterizing IEI, clinical immunologists and basic immunology researchers require an accessible resource that bridges fundamental principles with disease-specific diagnostic applications, alongside guidance valuable to laboratory professionals, students, and early-career practitioners.The reference covers flow cytometry principles, emerging technologies, technical considerations, and quality standards, alongside a framework for classifying IEI, before turning to practical diagnostic approaches for major disease categories. Protocols, diagnostic algorithms, immunophenotyping strategies, and functional assays demonstrate how flow cytometry rapidly identifies cellular and functional abnormalities to support diagnosis, while addressing its complementary role alongside molecular testing, narrowing candidate diagnoses, guiding genetic testing, and confirming genetic findings. Discussion of predictive and prognostic markers and international clinical experience extends its relevance across high-resource and resource-limited settings.Flow Cytometry-based Diagnosis for Inborn Errors of Immunity equips clinicians, laboratory professionals, and researchers with the knowledge and tools to translate flow cytometric findings into accurate diagnosis and informed patient care, strengthening the diagnostic pathway for IEI.

  • Avian Models of Development

    • 1st Edition
    • Volume 173
    • English
    Avian Models of Development provides practical and experimental approaches for using avian systems to study developmental processes. It covers key methods, model applications, and emerging techniques that support research in embryogenesis, tissue formation, gene function, and developmental mechanisms.

  • Virtual Possibilities

    Extended Reality as Assistive Technology for Inclusive Care
    • 1st Edition
    • Samiya Khan
    • English
    Virtual Possibilities: Extended Reality as Assistive Technology for Inclusive Care provides invaluable insights for researchers and related medical professionals into the transformative potential of virtual reality as a technological aid. The book navigates through the diverse applications of virtual reality in healthcare, transcending traditional uses such as medical training and therapeutic interventions. It is a dedicated examination of virtual reality's role in social care, addressing the unique needs of individuals across the spectrum, from differently abled individuals and children with learning disabilities to those grappling with disorders, trauma, and the elderly. It presents the state-of-the-art in this field, acting as a bridge, facilitating the translation of theory into practice and fostering ongoing research. Users will find this to be a valuable resource for researchers, professionals, and policymakers interested in the future applications of virtual reality in healthcare and social care.

  • Dietary Fiber

    Extraction, Properties and Modifications for Food Applications
    • 1st Edition
    • Tabli Ghosh + 1 more
    • English
    Dietary Fiber: Extraction, Properties and Modifications for Food Applications is an essential resource for food scientists and researchers seeking to understand the full potential of dietary fiber in the food industry. The book highlights fiber's various sources and critical health benefits, including detailed discussions on extraction techniques, characterization, and functional properties, equipping readers with the knowledge needed to innovate and enhance food formulations. Sections explore advanced topics such as nano and microencapsulation techniques that enhance fiber stability and bioavailability and the role of dietary fiber in gut health, microbiome modulation, and broader health implications.As the demand for healthier, functional foods grow, this book addresses the challenges of modifying dietary fiber to improve its solubility, viscosity, and stability through an array of physical, biological, chemical, and alternative methods. Readers will walk away with the knowledge needed to tailor dietary fiber for specific applications in functional food products and precision nutrition for better health outcomes.

  • AI-Driven Pharmaceutical Manufacturing

    Regulatory Innovation for Industry 5.0
    • 1st Edition
    • Vivek P. Chavda + 3 more
    • English
    AI-Driven Pharmaceutical Manufacturing: Regulatory Innovation for Industry 5.0 addresses the critical intersection of artificial intelligence, regulatory compliance, and human-centric innovation in drug product manufacturing. This reference responds to the growing need for advanced technological integration in pharmaceutical production, focusing on how AI and machine learning can optimize manufacturing processes while meeting stringent regulatory demands globally. It fills the knowledge gap for professionals navigating the complex landscape of Industry 5.0 in pharma. The book is structured into five key sections covering digital and regulatory foundations, pharmaceutical manufacturing practices, AI applications in drug development, regulatory compliance challenges, and future trends including cybersecurity and supply chain optimization. Each chapter provides foundational concepts, detailed methodologies, case studies, and practical implementation strategies, ensuring readers gain a thorough understanding of AI's role in pharmaceutical manufacturing. "AI-Driven Pharmaceutical Manufacturing" benefits professionals in manufacturing, regulatory affairs, quality assurance, and technology leadership by delivering actionable knowledge to implement AI/ML responsibly. It equips readers to overcome regulatory challenges, optimize production workflows, and foster sustainable human-machine collaboration, making it an indispensable resource for advancing pharmaceutical manufacturing into the Industry 5.0 era.

  • Neurological and Neuropsychiatric Disorders

    Substance Use and Addictive Behaviors
    • 1st Edition
    • Alexander Baldacchino + 1 more
    • English
    Neurological and Neuropsychiatric Disorders: Substance Use and Addictive Behaviors is an essential resource that delves into the intricate relationship between substance use, addictive behaviors, and their profound impact on neurological and neuropsychiatric health. The book presents a comprehensive examination of the various disorders and conditions that arise from, or are exacerbated by, substance use and addictive behaviors, offering a multidisciplinary approach to understanding these complex interactions. This volume provides a detailed and updated exploration of the neurological and neuropsychiatric consequences of substance use and addictive behaviors.By compiling the latest research and clinical insights, this volume aims to fill a critical gap in the existing literature, which often treats substance use disorders and neurological impacts as separate entities. This integrated approach is crucial for both researchers and clinicians who need a thorough understanding of the co-morbidities associated with addiction. This book solves the problem of fragmented knowledge by offering a unified perspective that is crucial for developing effective treatment strategies and understanding the full spectrum of addiction-related disorders.

  • Sustainable Solutions for Food Waste

    From Recovery to Resource Efficiency
    • 1st Edition
    • Gulsun Akdemir Evrendilek
    • English
    SSustainable Solutions for Food Waste: From Recovery to Resource Efficiency examines the magnitude, causes, and environmental impacts of food waste and presents sustainable strategies for its reduction, recovery, and valorization. The book highlights innovative technologies and practical approaches for transforming food and agricultural waste streams into valuable products and resources.Featuring contributions from experts in the field, it provides comprehensive perspectives on waste generation, management, utilization, and valorization across diverse food and agricultural industries, including grape and winery, fruit juice, olive and olive oil, tea and coffee, brewery and distillery, dairy, citrus, meat, seafood, seaweed, tropical fruits, vegetables, tuberous plants, rice, and medicinal and aromatic plants.Organized into four sections, the book addresses food waste, sustainability, valorization, and resource efficiency. Section 1 introduces the magnitude, causes, environmental impacts, and sustainable management of food waste. Section 2 focuses on waste from major food-processing industries. Section 3 explores waste utilization and valorization from plant-based and agricultural sources. Section 4 examines innovative technologies, circular economy approaches, resource recovery, sustainable food-waste management, and business models for resource efficiency.

  • Protein-Based Hydrogels

    Exploring the Roles of Protein Hydrogels in Membrane-less Organelles, Disease Mechanisms, and Therapeutic Applications
    • 1st Edition
    • Vladimir N. Uversky + 1 more
    • English
    Protein-Based Hydrogels: Exploring the Roles of Protein Hydrogels in Membrane-less Organelles, Disease Mechanisms, and Therapeutic Applications presents a comprehensive overview of natural and engineered protein hydrogels, examining their critical roles in cellular organization, disease pathology, and therapeutic innovation. This book contributes unique value by integrating fundamental biology, cutting-edge biotechnology, and translational biomedical science to address emerging questions about protein phase separation and gelation. Structured into three sections, the book begins by exploring the physiological functions of protein hydrogels in phase-separated organelles, cellular stress sensing, memory formation, and compartmentalization... It then investigates the pathological consequences of hydrogel dysregulation, including their roles in neurodegenerative diseases, cancer, and viral infections. Finally, it examines biomedical applications such as controlled drug delivery, regenerative medicine, biosensing, and the design of synthetic organelles. Each chapter is contributed by a leading expert, offering multidisciplinary perspectives from biochemistry, molecular biology, bioengineering, and medical research. This book is a valuable resource for academic researchers, graduate students, and professionals working in protein engineering, structural biology, molecular medicine, and pharmaceutical sciences. It supports readers in understanding the full spectrum of protein hydrogel biology—from cell physiology to disease mechanisms and therapeutic design—making it especially relevant for those interested in neurodegeneration, cancer biology, and translational bioengineering.

  • Animal Cognition

    Fundamentals, Models, and Therapeutic Advances
    • 1st Edition
    • Shampa Ghosh + 3 more
    • English
    Animal Cognition: Fundamentals, Models, and Therapeutic Advances provides a comprehensive overview of cognitive processes in various animal species, spanning fundamental concepts, species-specific studies, and therapeutic applications. Sections cover the foundation of animal cognition, including definitions, key concepts, and an overview of cognitive abilities, such as memory, problem-solving, and learning, delve deeper into the cognitive processes in mammals, birds, and marine animals, and more, and review the latest technological advancements in studying cognition, such as neuroimaging, machine learning, and virtual reality. With a multidisciplinary approach, this volume highlights current research while identifying gaps for future exploration, and will be of interest to researchers involved in animal cognition and behavioral neuroscience.

  • The Human Electroretinogram

    A Diagnostic Guide
    • 1st Edition
    • Benedetto Falsini
    • English
    The Human Electroretinogram: A Diagnostic Guide describes the physiological basis and clinical applications of the human electroretinogram (ERG). Several sub-types of ERGs are evoked by Full-Field stimuli, with characteristics that depend critically on the properties of the stimulus. This book discusses the human retina’s high sensitivity to light and its ability to respond robustly to even single quanta of light. Specifically, it clarifies that the major components of flash ERG, the a-wave and b-wave, are generated by photoreceptors and bipolar cells, respectively. This book explores how changes in light intensity, adaptation, and temporal frequency can alter the contributions of different retinal generators (e.g., rods, cones, and bipolar cell subtypes). In addition to Full Field ERG, other important diagnostic electroretinograms including focal, multifocal, and pattern ERGs are clarified. This book uniquely illustrates the combined use of these ERG tools, allowing clinicians to perform a functional dissection of the retina and achieve a layer-by-layer analysis.The approach of The Human Electroretinogram: A Diagnostic Guide correlates with retinal layer evaluations performed using modern multimodal imaging techniques, such as optical coherence tomography (OCT). ERG analysis exemplifies a critically important tool for early diagnosis, follow-up, and treatment monitoring of retinal diseases involving different retinal layers. This book is essential in providing ophthalmological professionals with the know-how to manage the interplay between these numerous elements.

  • Advancements in Digital Cytopathology and Artificial Intelligence

    • 1st Edition
    • Keluo Yao + 2 more
    • English
    Advancements in Digital Cytopathology and Artificial Intelligence offers an extensive and reliable resource for those intrigued by the opportunities for employing artificial intelligence in cytopathology, within both clinical and research settings. The book provides advances in research and commercial technologies, regulatory and business environment updates and special considerations in cytopathology that impacts AI applications in the medical field. It describes the current state of cytopathology digitization and AI technologies, the current cytopathology practice environment, including laws and compliance issues in the context of digitization and AI technologies. This an essential reference for cytologists and trainees who are interested in AI and digital pathology and AI researchers and industry partners who are interested in developing applications for cytopathology.

  • Clinical Management of Pancreatic Cancer

    From Diagnosis to Palliative Care
    • 1st Edition
    • Takuji Okusaka + 1 more
    • English
    Clinical Management of Pancreatic Cancer: From Diagnosis to Palliative Care provides comprehensive guidance and support at every step of the pancreatic cancer journey, covering all aspects from initial diagnosis to compassionate and holistic care, ensuring healthcare professionals have the knowledge and resources they need for effective management and improved quality of life. The book not only presents the latest advancements in pancreatic cancer management, including innovative surgical techniques, targeted therapies, radiotherapy approaches, and palliative care interventions but also focuses on maintaining and improving patients' quality of life throughout their journey, incorporating palliative medicine and supportive care to alleviate symptoms and enhance overall well-being. IN 4 sections and 29 chapters Clinical Management of Pancreatic Cancer: From Diagnosis to Palliative Care Advocates for patient-centered care by emphasizing communication, shared decision-making, and tailoring treatment approaches to individual needs and preferences. It raises awareness about pancreatic cancer, its challenges, and the importance of early detection, while also dispelling misconceptions and offering hope through informed management strategies. The book also highlights the significance of palliative medicine and comprehensive supportive care to manage symptoms, alleviate pain, and address psychosocial and emotional needs of both patients and their families.Clinical Management of Pancreatic Cancer: From Diagnosis to Palliative Care serves as a bridge between research and clinical practice, offering researchers a broader perspective and equipping clinicians with a valuable resource that enhances their knowledge, decision-making, and patient care skills in the realm of pancreatic cancer management.

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, 5th Edition is the definitive text on clinical research, written by internationally recognized experts in their field, from the US National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. The new edition contains fully updated chapters, with more than 50 new authors and 15 new chapters. The book continues a strong emphasis on study design and biostatistics in clinical research, with new chapters containing fresh information on a variety of topics, including chapters on how to engage a full range of research participants and research opportunities for people involved in patient care including surgeons, pharmacists, and other clinical researchers. For the international researcher, two new chapters detail international clinical research experiences in South Africa and India. As with the 4th edition, the new edition provides readers with summary questions and answers after select chapters.

  • Biophysical Nutrition

    How Environments Shape Diets from Earth to Space
    • 1st Edition
    • Vidyullatha Peddireddy + 1 more
    • English
    In an era where human exploration extends beyond Earth and personalized nutrition has become a cornerstone of health, understanding how environments influence dietary needs is paramount. Biophysical Nutrition: How Environments Shape Diets from Earth to Space bridges the divide between nutritional science and biophysics and sheds light on the physical principles that govern digestion, absorption, and metabolism across terrestrial and extraterrestrial settings.Divided into three comprehensive sections, Biophysical Nutrition: How Environments Shape Diets from Earth to Space explores foundational concepts such as thermodynamics of metabolism and membrane biophysics, while addressing adaptation mechanisms to extreme environments including microgravity and spaceflight. It highlights innovative approaches to space agriculture, dietary delivery systems, and alternative proteins designed for long-duration missions. Emphasizing translational applications and ethical considerations, this book equips researchers and professionals with the tools to design personalized nutrition strategies informed by biophysical modeling for challenging environments including Space. Essential for researchers in nutrition science, biomedical fields, and planetary science, this work paves the way for future innovations in dietetics from Earth’s most challenging environments to celestial habitats.

  • Exploring Infant Cry

    Medical and Technical Analysis and Signal Processing Perspectives
    • 1st Edition
    • Carlos Alberto Reyes Garcia + 3 more
    • English
    Exploring Infant Cry: Medical and Technological Analysis and Signal Processing Perspectives is a comprehensive exploration of the latest medical and technical advancements in the study of infant crying. This book presents a unified approach that integrates medical insights and computational techniques for analyzing and classifying cries, aiming to enhance diagnostic capabilities. Authored by experts, it emphasizes the growing significance of cry analysis as a powerful, non-intrusive tool for identifying pathologies from the earliest stages. As the field expands, researchers and clinicians are offered innovative perspectives and practical solutions for interpreting and understanding why babies cry. The book also explores the connection between infant cries and language development, as well as the communicative importance of these signals in human interaction. Addressing gaps in routine neonatal application, the book compiles recent advancements in signal processing, Artificial Intelligence, and soft computing for cry classification. This makes it a valuable resource for biomedical researchers, doctors, and clinicians seeking to deepen their knowledge of the acoustic, neurophysiological, and linguistic aspects of infant crying.

  • Asiatic-Pacific Ticks

    Species of Medical and Veterinary Importance
    • 1st Edition
    • Ze Chen + 1 more
    • English
    Asiatic-Pacific Ticks: Species of Medical and Veterinary Importance provides the most comprehensive and updated research on the taxonomy, biology, and bionomics of tick species native to the Palearctic and Oriental zoogeographic regions. It synthesizes all current research on each species using global perspectives, as these species begin to spread beyond their native habitats.Written and edited by international experts on the ticks of eastern Asia, this book covers the 12 primary species, including the Asian longhorned tick and those under the Hyalomma genus. Each chapter begins by discussing the species’ classification history, followed by identification descriptions for all active life stages, and a detailed discussion of biology and bionomics. The chapters end with a discussion of pathogenic agents associated with each species and their context for human and animal ecology.Asiatic-Paci... Ticks: Species of Medical and Veterinary Importance is a vital resource for entomologists, both in human-medical and veterinary focuses. Public health personnel and parasitologists tracking diseases in tick species will also find this useful.

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