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Elsevier

Books in Life sciences

  • Enzymology in Drug Discovery

    • 1st Edition
    • Volume 747
    • English
    This volume is focused on the application of enzymology to drug discovery, with the overarching objective of introducing the general audience to the important role that enzymology plays in modern, molecular targeted drug discovery. The volume opens with a chapter on the role of enzymes in normal human physiology and the causal role played by aberrant enzyme activity in various disease state. A second chapter provides a comprehensive review of inhibition modalities for therapeutic enzyme inhibitors. From there the volume is composed of chapters that cover two general categories of information: (1) methodologies for studying enzyme-ligand interactions and (2) case studies of molecular targeted drug discovery against specific enzyme targets. Chapters within the first category cover methods such as assay design, the role of structural biology in drug optimization, analysis of slow and tight binding inhibitors, enzyme-inhibitor complex dynamics, and covalent enzyme inactivators. The second category includes case studies of therapeutic inhibitors of various enzyme target classes: proteases, methyltransferases, histone demethylases, helicases, nucleic acid processing enzymes, kinesin motor proteins, and cytochrome P450s. Finally, a chapter is also devoted to therapeutic replacement or repair of defective enzymes.

  • Endovascular Therapy for Intracranial Atherosclerotic Stenosis

    • 1st Edition
    • Ning Ma + 1 more
    • English
    Endovascular Therapy for Intracranial Atherosclerotic Stenosis presents selected cases of endovascular treatment for intracranial atherosclerotic stenosis (ICAS), providing detailed information on periprocedural medical management, endovascular strategies, device selection, and follow-up outcomes. The book serves to improve understanding of ICAS and share clinical experiences from high-volume stroke intervention centres with neuro-interventional... The book reviews recent developments in ICAS management and presents evidence that appropriate patient selection and peri-operative planning may contribute to the effectiveness of endovascular therapy for ICAS

  • Current Approaches to Overcome Therapeutic Resistance of Leukemia

    • 1st Edition
    • Zhe-Sheng Chen + 2 more
    • English
    Current Approaches to Overcome Therapeutic Resistance of Leukemia presents a comprehensive academic resource addressing the persistent challenge of treatment resistance in leukemia. It explores biological, molecular, and clinical dimensions of resistance, bridging fundamental research with therapeutic innovation. The book examines key resistance mechanisms, including genetic mutations, leukemic stem cells, and tumor microenvironment interactions, alongside emerging insights such as epigenetic regulation, metabolic reprogramming, and immune evasion. It further highlights advanced therapeutic approaches, including immunotherapy, targeted therapies, combination strategies, and AI-driven tools for drug discovery and monitoring. This volume provides students, researchers, and clinicians with foundational and integrated knowledge essential for understanding resistance biology and translating discoveries into clinical practice. It supports evidence-based decision-making and promotes the development of innovative strategies to improve patient outcomes.

  • Cognitive Remediation in Psychiatric Disorders Part B

    Other Conditions, Contexts and Considerations
    • 1st Edition
    • Volume 307
    • English
    Cognitive Remediation in Psychiatric Disorders is a two-volume work comprising Part A: Core Psychiatric Conditions (Volume 306) and Part B: Other Conditions, Contexts and Considerations (Volume 307). Together, the volumes provide a comprehensive, contemporary account of cognitive remediation and related cognition-oriented interventions across psychiatric, neurodevelopmental, lifespan, and other clinical contexts. Part A establishes the historical, conceptual, and practical foundations of cognitive remediation and examines its application across psychosis, serious mental illness, depression, bipolar disorder, obsessive-compulsive disorder, substance use disorders, and trauma-related disorders. Part B extends the discussion to personality disorders, eating disorders, behavioral addictions, ADHD, autism spectrum disorder, intellectual and developmental disabilities, cognitive concerns in older adults, HIV-associated neurocognitive disorders, multiple sclerosis, cognitive difficulties following electroconvulsive therapy, and emerging technology-enabled approaches. Across both volumes, contributors address intervention principles and mechanisms, clinical integration, adaptation and accessibility, metacognition and subjective cognition, memory, real-world skill acquisition, and functional and vocational outcomes. Together, the volumes provide a broad, integrated framework for understanding how cognition-oriented interventions can support recovery, participation, and everyday functioning across diverse clinical populations.

  • AI and Global Health

    Unlocking Transformative Potential
    • 1st Edition
    • Adil Haider
    • English
    AI and Global Health: Unlocking Transformative Potential provides a roadmap for practitioners to apply and leverage artificial intelligence to strengthen health systems using the World Health Organization's health systems approach. The book's combination of case studies and secondary research inspires the possibility of what can happen using AI in healthcare, ensuring the use of robust, scientific evidence to draw conclusions. Additionally, readers will learn from others in settings where AI has been a tool for change, providing healthcare practitioners and policymakers with what they need to think through how it can be applied in resource limited settings.The book provides a strong call to action for policymakers and healthcare leaders of governments, international organizations, and healthcare institutions to take the lead in AI implementation as a key lever for advancing global health goals through a systems approach. As AI is a rapidly evolving field with significant investment made in this industry in recent years from government and the private sector, this book articulates how this growth can be harnessed for countries that need a different approach to addressing global health problems.

  • Molecular Chaperones in Neurodegenerative Diseases

    • 1st Edition
    • Volume 156
    • English
    Molecular Chaperones in Neurodegenerative Diseases explores the roles of molecular chaperones in maintaining protein homeostasis and their involvement in the onset and progression of neurodegenerative disorders. The book highlights current research on chaperone-mediated mechanisms, disease pathology, and emerging therapeutic approaches targeting protein misfolding and aggregation.

  • Childhood Disorders of Rickets and Osteomalacia

    A Comprehensive Review
    • 1st Edition
    • Suma Uday
    • English
    Childhood Disorders of Rickets: A Comprehensive Review defines the pathophysiology of rickets and the various genetic and acquired conditions that present with rickets in childhood. This comprehensive review details the various forms of rickets, the histopathology, recent advances leading to new therapeutic options in treating rickets, and the role of Vitamin D and calcium in nutritional rickets. Additionally, the authors explore future research in various areas of nutritional and non-nutritional forms of rickets.Written by global experts for clinicians and researchers treating and studying the various forms of rickets, the book will also be of interest to those working in public health and policy makers working on the prevention of nutritional rickets worldwide.

  • Operative Strategies in Pelvic Exenteration Surgery

    • 1st Edition
    • Michael E Kelly + 1 more
    • English
    Operative Strategies in Pelvic Exenteration Surgery is a reference for the surgical management of Pelvic Exenteration Surgery. It covers all aspects of surgery from the colorectal, urological, gynecological, and orthopedic point of view. Coverage consolidates the research of world-leaders and includes the history of exenterative study, outlining the current state and indicating future developments. The book also discusses the current surgical operative strategies for the management of locally advanced and recurrent pelvic neoplasms with illustrations, intra-op photos, and supplementary video material.Created from the experiences of an international collaboration of surgeons, this reference is the perfect reference for surgical oncologists, colorectal, gynecology, urology, and vascular surgeons as well as any group involved in complex pelvic surgery including complex open, laparoscopic, and robotic surgery.

  • Emergent Nanotherapeutics in Diabetic Complications

    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Emergent Nanotherapeutics in Diabetic Complications explores how cutting-edge nanotechnology is transforming the treatment of diabetes-related disorders beyond glycemic control. This comprehensive volume examines targeted, multifunctional nanoplatforms designed to address the wide range of comorbidities linked to diabetes, including vascular complications, metabolic dysfunctions, and impaired wound healing. Structured in five parts, the book spans from current nanoformulation strategies to emerging innovations such as CRISPR-Cas9 delivery, AI-guided nanoparticles, and 3D/4D printed nanostructures.Bridg... the gap between preclinical research and clinical application, it offers valuable guidance on stimuli-responsive systems, biocompatible materials, and regulatory pathways. This is essential resource for medical professionals, biomedical engineers, and pharmaceutical scientists seeking scalable, next-generation solutions for managing diabetic complications through nanomedicine.

  • Nutritional and Health Aspects of Food in North Asia, Volume 1

    • 1st Edition
    • Lijing Ke + 2 more
    • English
    Nutritional and Health Aspects of Food in North Asia, Volume 1, is part of Elsevier's ongoing Traditional and Ethnic Food Series, complementing other volumes in the series by providing deeper scientific insight into traditional and ethnic foods from regions around the world. Supported by the Global Harmonization Initiative (GHI), an international, non-profit network of food scientists and organizations dedicated to achieving global consensus on the availability of safe, healthy food worldwide, this volume offers a representative, comprehensive, scientific review of the traditional and ethnic foods native to North Asia, specifically China, Korea, and Taiwan. It explores the history, cultural heritage, composition, preparation, nutritional value, and scientific understanding supported by modern scientific research and data, while highlighting the health-promoting properties of well-established iconic regional traditional foods such as kimchi, tea phenolics, soy-based products, fermented vegetables, and rice-based dishes, to name a few. Through contributions from leading local experts, Nutritional and Health Aspects of Food in North Asia, Volume 1, discusses the challenges and opportunities in harmonizing food regulations to facilitate the global availability of these culturally significant healthy foods. An essential resource for food and nutrition scientists, food industry professionals, policymakers, and regulators, this volume examines how traditional and historical eating habits continue to shape diets across North Asia.

  • Ethnopharmacological Strategies for Diabetes-Associated Reproductive Co-morbidities

    Evidence-Based Molecular Mechanisms and Clinical Outcomes
    • 1st Edition
    • Debidas Ghosh + 3 more
    • English
    Ethnopharmacological Strategies for Diabetes-Associated Reproductive Co-morbidities: Evidence-Based Molecular Mechanisms and Clinical Outcomes is a comprehensive, interdisciplinary reference addressing the complex link between diabetes mellitus and infertility in both men and women. This edited volume synthesizes molecular insights into diabetes-induced reproductive dysfunction—such as oxidative stress, inflammation, endocrine disruption, and tissue damage—with evidence-based evaluations of medicinal plants and their bioactive phytochemicals. It bridges laboratory research and clinical trials to highlight how plant-derived compounds can regulate glycemic control, restore hormonal balance, reduce oxidative damage, and improve gametogenesis. Targeting clinicians, researchers, and postgraduate students in biomedical and pharmaceutical sciences, the book offers detailed therapeutic profiles, safety assessments, and translational applications. By consolidating fragmented knowledge, it empowers healthcare professionals and scientists to develop integrative, cost-effective strategies for managing diabetes-related infertility.

  • Brain-Computer Interfaces (BCI)

    • 1st Edition
    • Volume 229
    • English
    Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Reasoning

    An Integrative Approach
    • 2nd Edition
    • Daniel Krawczyk
    • English
    Reasoning: An Integrative Approach, Second Edition provides an overview, summary, and synthesis of research approaches to the psychology of reasoning. Representing historical perspectives, state-of-the art research, and coverage of upcoming future directions, this volume offers an integrative approach including research on animal behavior, neuroscience, cognitive psychology, AI, development, medicine, and philosophy. The contents range from animal studies through applied situations, and present historical perspectives, discussion of both animal reasoning and human reasoning to provide a cross-species context, and an examination of human reasoning across the lifespan. Though intended primarily for neuroscientists, the book will provide an interdisciplinary examination of reasoning, synthesizing perspectives from neuroscience, cognitive psychology, animal behavior, development, and philosophy, to provide readers with a well-rounded understanding of what reasoning is, various types of reasoning, and its role in decision making and social interactions. New to this edition is research on the influence of technology throughout the book, as well as a greater emphasis on the way that cultural backgrounds and variations in our exposure to information influence our thinking. This will enhance the scope, relatability, and diversity of the book, making it more applicable to future practices and research.

  • Biopolymers for 3D Tissue Engineering

    Processing and Applications
    • 1st Edition
    • Narendra Reddy + 1 more
    • English
    Biopolymers for 3D Tissue Engineering: Processing and Applications explores the critical role of biopolymers in advancing tissue engineering and 3D cell culture—key technologies in drug discovery, personalized medicine, and disease treatment. The book provides a comprehensive overview of the structure, properties, and processability of biopolymers with a focus on innovative techniques for converting them into functional scaffolds suitable for 3D cell culture. Sections cover carbohydrates, proteins, and synthetic biopolymers in a single, authoritative source, making it invaluable for students, researchers, professionals, and industry stakeholders.As scaffolds form the foundation of these applications, current options—primarily synthetic polymers like polypropylene, polyethylene, or polystyrene, and some natural materials such as collagen and silk fibroin—are often expensive and lack optimal properties such as biocompatibility, biodegradability, and mechanical stability. This book addresses the global effort to develop next-generation scaffolds that overcome these limitations. As biopolymers offer a compelling solution, with inherent biodegradability, biocompatibility, and sustainability, this book guides on the latest technologies and innovations.

  • The Evolution of Artificial Intelligence in Healthcare and Medicine

    From Basic Methods to Clinical Practice
    • 1st Edition
    • Mario Cannataro
    • English
    The Evolution of Artificial Intelligence in Healthcare and Medicine: From Basic Methods to Clinical Practice explores revolutionary technological advancements in the medical and healthcare realms due to generative AI and Deep Learning. This comprehensive guide not only explores cutting-edge technologies such as transformers and large language models for newcomers but also demystifies advanced applications like sequential decoding techniques and segmentation algorithms rarely explored in other literature. Sections cover foundational concepts and terminologies, explore deep learning and generative AI, provide AI's role in biomedical research, examine its integration into clinical practice, scrutinize its applications in public health, and discuss challenges and future prospects.This is an indispensable resource for healthcare professionals, scientists, researchers, students, and enthusiasts seeking to deepen their understanding of this rapidly evolving field.

  • Current Research on Biofilm Mediated Chronic Diseases

    Immunological Background and Clinical Interpretations
    • 1st Edition
    • Dibyajit Lahiri + 3 more
    • English
    Current Research on Biofilm Mediated Chronic Diseases: Immunological Background and Clinical Interpretations is an in-depth exploration of the complex interplay between biofilms, the immune system, and chronic diseases. These microbial communities, encased in self-produced extracellular polymeric substances (EPS), adhere to surfaces and resist environmental stresses, including host immune responses and antimicrobial agents.This comprehensive book investigates the formation, characteristics, and profound impact of biofilms on human health. Coverage spans the fundamentals of biofilm formation, immune evasion, and antimicrobial resistance (AMR); the role of biofilms in chronic diseases including periodontal disease, chronic wounds, and respiratory and urinary tract infections; their involvement in cancer development and neural disorders via the gut-brain axis; emerging therapeutic strategies such as nanotechnology, phage therapy, and immunomodulatory approaches; and the growing application of artificial intelligence (AI) and machine learning to biofilm-immune interactions and personalized medicine.Current Research on Biofilm Mediated Chronic Diseases: Immunological Background and Clinical Interpretations provides essential insights for researchers, undergraduates, and postgraduates seeking to understand and combat the challenges posed by biofilms in chronic disease pathology. This book offers valuable knowledge on recent techniques for detecting and mitigating antimicrobial resistance (AMR) and biofilm formation, making it an indispensable resource for scientists and clinicians alike.

  • Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part B

    • 1st Edition
    • Volume 193
    • English
    Blood-Based Biomarkers for Alzheimer's and Parkinson's Disease – Part B, published as Volume 193 of the serial International Review of Neurobiology, provides a comprehensive examination of emerging blood-based biomarkers and related biological mechanisms relevant to Alzheimer's disease, Parkinson's disease, vascular cognitive impairment, stroke, and other neuropsychiatric disorders. The volume highlights advances in biomarker discovery, genetic and epigenetic determinants of neurodegeneration, extracellular vesicles and exosomes, protein misfolding, microRNA dysregulation, blood-brain barrier dysfunction, and biofluid-based biosensing technologies. It also explores the integration of artificial intelligence with multimodal biomarker datasets to improve diagnosis, prognosis, and precision medicine approaches. Bringing together contributions from international experts, this volume offers researchers and clinicians an up-to-date resource on translational developments that are shaping the future of neurodegenerative disease detection and management.

  • Application of Python in the Healthcare Technology

    Medical Data Analysis and Developing ML/AI Models
    • 1st Edition
    • Praveen Kumar M
    • English
    Application of Python in Healthcare Technology: Medical Data Analysis and Developing ML/AI Models provides comprehensive coverage of the Python programming language from a medical-based perspective. With a strong focus on utility-based learning rather than technical-based learning of Python, this title clarifies how the application of Python in the healthcare technology industry has a meaningful impact on patient care through the development of deep learning models for early prediction of diseases and the development of Clinical Decision Support System (CDS). In 13 chapters, an extensive range of topics pertaining to the intersection of Python and medical sciences is covered. Coverage defines how to set up an environment to work with python, describes Python class, methods, and functions, explains both basic and advanced statistical analysis in Python, and provides a tool to assist in the development of deep learning models such as API, Git, Github, NumPy, Pandas, and SciPy.

  • Current Advances in Cancer Stem Cells and Neoplasia Research

    • 1st Edition
    • Volume 8
    • Hirendra Banerjee
    • English
    Cancer, Volume 8 in the Stem Cell Innovation in Health and Disease series explores the rapidly evolving role of stem cells in cancer treatment. As cancer continues to impose a heavy global health burden, stem cell therapies are being recognized for their regenerative potential and ability to enhance recovery following aggressive therapies. Hematopoietic stem cell (HSC) transplantation is already a standard, FDA-approved treatment for hematologic cancers such as leukemia, myeloma, and lymphoma. These cells help regenerate healthy blood cells post-treatment. In addition, mesenchymal stem cells (MSCs) and neural stem cells (NSCs) are showing promise in preclinical models as therapeutic carriers, capable of homing to tumor sites and delivering anti-cancer agents such as nanoparticles, siRNAs, and small-molecule drugs. Recent clinical advancements include differentiation therapy, where stem cells are used to induce cancer cells to become non-cancerous. Two completed phase I clinical trials have demonstrated innovative applications: one using NSCs to convert a prodrug into a toxic compound within tumors, and another using MSCs engineered with viral enzymes to activate cytotoxic drugs directly at the tumor site. MSCs have also helped reduce graft-versus-host disease (GVHD), a major complication of stem cell transplants. This volume is divided into two main sections: understanding stem cell roles in cancer biology, and translating stem cell innovations into clinical practice. It features cutting-edge research, including organoid models, genetic editing, and iPSC technologies. Together, these insights offer a timely review of the field’s progress and its real-world potential to reshape cancer therapy.

  • Advances in Preservation and Packaging for Milk and Dairy Products

    • 1st Edition
    • Roji Waghmare + 1 more
    • English
    Preservation and shelf-life extension make food safe to eat and accessible to people all over the world, significantly reducing spoilage and waste. As a particularly perishable food group, milk and dairy products require highly effective methods of preservation and packaging in the ever-changing global food supply chain. Advances in Preservation and Packaging for Milk and Dairy Products provides in-depth knowledge of the methods and technologies used to ensure the safety, quality and shelf life of milk and dairy products. This book begins with an overview of the fundamental principles and challenges of preserving milk and dairy products. It progresses to discuss advances in both conventional and emerging preservation techniques, from thermal and fermentation methods to non-thermal technologies like high-pressure processing, pulsed electric fields, and cold plasma. This book also provides a comprehensive overview of packaging innovations, including biodegradable and active packaging. Taking an interdisciplinary approach,Advances in Preservation and Packaging for Milk and Dairy Products is a comprehensive guide for food scientists, researchers, and industry professionals working to innovate in the dairy sector.

  • Trauma During Pregnancy

    • 1st Edition
    • Jorge Hidalgo + 2 more
    • English
    Surgical Care of the Critically Ill During Pregnancy, a volume in the Critical Care Obstetrics series, is a novel reference to educate physicians, nurses, and all allied healthcare personnel caring for pregnant women in all surgical aspects including trauma. The book's authors offer best practices and evidence-based material explicitly focused on the most common complications in pregnant patients that may occur to improve patient care. It not only covers critical care investigation from medical-surgical complications that any patient can present, but also how to prepare and anticipate complications in the critical care unit.

  • Laboratory Sleep Medicine

    Fundamentals of Sleep Technology
    • 1st Edition
    • Ravi Gupta + 2 more
    • English
    Laboratory Sleep Medicine: Fundamentals of Sleep Technology, is the second of the Fundamentals of Sleep Technology series, discusses balancing the fundamentals of sleep medicine with the newest innovations in the lab. High priority is given to practices that must be followed in sleep labs to guarantee the safety of patients and workers. To make information straightforward and easy to grasp, key events in each epoch of polysomnography are showcased. This serves to walk sleep professionals cogently through the history of sleep technology advancement.Laborato... Sleep Medicine: Fundamentals of Sleep Technology is keenly aware that manual titration with PAP is the gold standard treatment for sleep apnea. However, certain patients may require oxygen treatment, which is also covered in depth. In addition, case vignettes illustrate the development of a relevant report using the following: data from a sleep diary, actigraphy, and polysomnography. How to do sleep tests in unusual situations (such as at-home sleep apnea testing and testing in an intensive care unit) are also covered.

  • The Brain Histaminergic System in Health and Disease

    • 1st Edition
    • Zhong Chen + 2 more
    • English
    Histamines in Neurology and Psychiatry summarizes histamines and their impact on neuroinflammation and brain development in key neural circuits. This book presents the latest research on the physiological regulation of a neuroendocrine responses and releases, broadly discussing histamine receptor modulators and histamine effects in neurology and psychiatry, and also including clinical applications that will be of interest to practitioners.

  • Pain Conditions of the Head and Face

    A Practical Guide to Diagnosis and Management
    • 1st Edition
    • Anat Galor + 1 more
    • English
    Pain Conditions of the Head and Face: A Practical Guide to Diagnosis and Management provides a user-friendly guide on diagnosing and managing common head and facial pain conditions using new methods and therapies. The book contains practical information, reviewing epidemiology, presenting key features, contributing mechanisms, and including treatment algorithms for common pain conditions of the head and face. Focus is given to aspects of disease that are novel and evolving, and all conditions are discussed within the framework of the latest advances in research and patient care.Doctors seeking to ameliorate their patients’ pain from such maladies as (among many others) neuropathic ocular pain, trigeminal neuralgia, herpetic neuralgia, temporomandibular disorders, burning mouth disorder, and neuropathic ear pain will require no other book to identify their patients’ illnesses and make sure they receive the care they need.

  • Metagenomics in Biotechnology

    Environmental, Industrial, and Clinical Applications
    • 1st Edition
    • Abd El-Latif Hesham + 3 more
    • English
    Metagenomics in Biotechnology: Environmental, Industrial, and Clinical Applications provides a comprehensive understanding of metagenomic biotechnology, including its underlying principles, techniques, and tools used for data analysis. It explores how metagenomics plays a crucial role in environmental and industrial applications, such as the identification and quantification of microbial communities, the bioremediation of pollutants, biofuel development, and sustainable agriculture. The book also delves into the clinical implications of metagenomics, from technological advancements, pathogen identification, detection, drug discovery, and development. This understanding helps aid in the design and implementation of innovative solutions to environmental, industrial, and clinical challenges. With current trends, challenges, and solutions in metagenomics rounding out the coverage, this book is a valuable resource for researchers, students, and professionals looking to deepen their knowledge of the various techniques used for data analysis and further leverage the potential of metagenomic biotechnology.

  • Lightweight Secure and Intelligent Approaches for Medical Devices

    Trends and Future Frontiers
    • 1st Edition
    • R. Praveen + 1 more
    • English
    Lightweight Secure and Intelligent Approaches for Medical Devices: Trends and Future Frontiers addresses the rapidly evolving intersection of artificial intelligence, Internet of Medical Things (IoMT), and edge computing within healthcare. This reference meets the critical demand for resource-efficient, secure, and trustworthy AI models tailored specifically for embedded medical devices operating under stringent constraints. By integrating advances in lightweight AI, medical device security, and intelligent data processing, the book fills a vital gap in current literature, offering researchers, engineers, and healthcare professionals a comprehensive resource to develop next-generation medical technologies. The book is organized into four parts, beginning with foundational concepts including the evolution of AI in healthcare devices, lightweight model design, and medical device security standards. It progresses to predictive intelligence and reliability, covering AI techniques for disease monitoring, device calibration, and personalized medicine. The security and privacy section explores network architectures, privacy-preserving AI, lightweight cryptography, and defenses against adversarial attacks. The final part presents emerging trends such as edge AI, digital twins, explainable AI, augmented and virtual reality applications, and quantum-safe security protocols. Each chapter combines theoretical insights with practical case studies and research perspectives to guide real-world deployment. Lightweight Secure and Intelligent Approaches for Medical Devices: Trends and Future Frontiers serves as an essential reference for researchers, medical device developers, cybersecurity professionals, and graduate students aiming to innovate secure and intelligent healthcare solutions in resource-constrained environments.

  • Halal Meat Production

    Challenges and Innovations
    • 1st Edition
    • Awis Qurni Sazili + 2 more
    • English
    With approximately 25% of the world's population identifying as Muslim, halal food encompasses an important part of global food production. Halal meat poses particular challenges as production increasingly grows in scale while regulatory standards must be maintained to keep animal welfare, handling, and slaughter practices in accordance with Islamic law. Halal Meat Production: Challenges and Innovations aims to compile the latest research and key background information on this topic, promoting additional research and improving existing practices. It will comprehensively explore recent scientific advances in halal meat production, including the fundamental concept of halal, animal welfare, and proper handling and restraining techniques. It will also address key challenges and critical topics, such as the use of stunning in halal slaughter, industrial-scale production, and cultured meat products.Halal Meat Production: Challenges and Innovations is written and edited by experts from around the world. This book offers an ideal resource for meat and livestock scientists as well as food regulatory agencies.

  • Fundamentals of 3D Food Printing and Applications

    • 2nd Edition
    • Fernanda C. Godoi + 4 more
    • English
    Fundamentals of 3D Food Printing and Applications, Second Edition offers a broad overview of 3D printing technology applied to food. This new edition outlines emerging 3D food printing technologies and their working mechanisms across a wide range of application areas, including the development of soft foods and confectionary designs. Chapters cover new trends and demands, such as changes in consumer preferences, new regulations, and new applications of 3D printing technology in the food industry. It also explores the use of natural and organic materials as printing materials to address end-user concerns about artificial food.In addition, the book covers the use of automated systems and advanced technologies, such as machine learning and artificial intelligence, to improve efficiency and consistency in 3D food printing. Case studies and best practices from industry professionals who have successfully scaled up their 3D food printing operations are presented throughout. Edited and written by a team of worldwide experts in 3D food printing, this book is the best resource covering the latest developments in 3D printing technology.

  • Dry Eye Disease

    A Clinical Handbook
    • 1st Edition
    • James Stuart William Wolffsohn + 2 more
    • English
    Dry Eye Disease: A Clinical Handbook illuminates the translation of cutting-edge research on dry eye disease into practical situations, allowing clinical diagnosis and management of the condition using the latest evidence-based methods. It first presents research on the core pathophysiological features of dry eye disease, including tear film instability, hyperosmolarity, inflammation, and ocular surface damage. Thereafter, it champions a patient-centered approach to dry eye management, emphasizing the necessity of classifying the ocular surface disease(s) most relevant to each case. It discusses global disease distribution and the role of non-modifiable risk factors like age, sex, and ethnicity. Additionally, the book describes tools for monitoring symptoms over time and assessing subtle signs of the disease. Readers will find practical methods for improving patient outcomes both in clinical settings and at home.

  • Fungal Biodeterioration and Biodegradation

    Insights into Fungal Behaviour, Mechanisms, and Applications
    • 1st Edition
    • Adesh Kumar + 3 more
    • English
    Fungal Biodeterioration and Biodegradation: Insights into Fungal Behaviour, Mechanisms, and Applications offers a comprehensive, interdisciplinary overview of fungi’s dual roles in environmental processes and material deterioration. Fungi are Earth's main recyclers, capable of breaking down complex substances like lignin, plastics, and pollutants. However, they also cause biodeterioration of food, artworks, textiles, and infrastructure, posing challenges across industries and conservation efforts. This book bridges molecular mechanisms with practical applications, providing researchers, conservators, and industry professionals with essential knowledge on how fungi interact with materials, pollutants, and microbial communities. It covers foundational topics such as fungal biology, enzymatic pathways, and colonization processes. The volume explores fungi’s role in degrading natural and synthetic polymers, petroleum products, and environmental contaminants, supported by case studies on cultural heritage preservation, bioremediation, and industrial waste management. Cutting-edge omics, enzyme engineering, and scalable biotech solutions are highlighted, along with future directions in fungal biotechnology and genetic engineering.Fungal Biodeterioration and Biodegradation equips professionals with scientific insights and practical strategies to harness fungi’s power for environmental cleanup, sustainable industry practices, and cultural conservation.

  • Plant Tissue Culture

    Techniques and Experiments
    • 5th Edition
    • Sunghun Park
    • English
    Plant Tissue Culture, Fifth Edition offers a practice-driven introduction to one of the most influential experimental platforms in plant science. Combining established methodologies with contemporary advances in biotechnology, it demonstrates how cultured cells, tissues, and organs can be used to explore plant development and morphogenesis, propagate valuable germplasm, generate novel variation, and support crop trait enhancement.Structur... around a series of laboratory exercises, the book enables technical proficiency alongside an in-depth understanding of the biological principles that govern cellular growth, function, and regenerative responses. Readers are guided through the investigative techniques that have shaped the field, from micropropagation and embryo rescue to protoplast technologies and plant transformation, illustrating how in-vitro systems continue to serve as powerful tools for both discovery and application.This fully revised edition also discusses the expanding relationship between culture-based methods and molecular approaches, including genome editing and RNA interference. Building on decades of established principles and placing cutting-edge developments in the broader context of plant research and agricultural innovation, the volume highlights the continuing evolution of a discipline that remains central to unlocking and harnessing plant potential.

  • Omics Bioprospecting of Beneficial Microorganisms in Sustainable Agriculture

    • 1st Edition
    • Sergio de los Santos Villalobos + 2 more
    • English
    Advances in high-throughput sequencing, systems biology, and microbiome science reveal unprecedented opportunities to harness microbial diversity for crop productivity, soil health, nutrient management, and pest and disease control. These technologies are enabling researchers to move beyond the simple identification of useful microorganisms toward a mechanistic understanding of their functions, interactions, and uses in agricultural systems.Omics Bioprospecting of Beneficial Microorganisms for Sustainable Agriculture examines how genomic, transcriptomic, proteomic, metabolomic, metagenomic, and integrated multi-omics approaches are accelerating the discovery and development of agricultural biologicals. Chapters cover plant-growth-promoti... and nutrient-solubilizin... bacteria, mycorrhizal and endophytic fungi, insect-associated microorganisms, bacteriophages, and plant-associated viruses, highlighting their roles in supporting plant health and ecosystem resilience.In addition to discovery pipelines, the book addresses emerging tools for community profiling, activity characterization, microbial engineering, and precision agriculture. Real-world applications and case studies demonstrate how these approaches are being translated into reduced reliance on chemical inputs and suited to specific crops and growing conditions.The volume concludes with discussions on biosafety, regulatory frameworks, commercialization challenges, climate resilience, and future directions for microbiome-based innovations. Bringing together perspectives from leading scholars across disciplines, it provides a comprehensive reference for scientists, agronomists, microbiologists, biotechnology professionals, and graduate students committed to strengthening food security.

  • Quercetin in Drug Discovery

    • 1st Edition
    • Gautam Sethi + 2 more
    • English
    Quercetin in Drug Discovery is a detailed reference exploring the multifaceted pharmacological potential of quercetin, a naturally occurring flavonoid with significant therapeutic promise. Addressing the critical need for consolidated knowledge, this guide highlights quercetin’s diverse biological activities and the translational challenges limiting its clinical applications, making it essential for researchers and pharmaceutical scientists. The comprehensive table of contents covers quercetin’s pharmacological properties, molecular docking studies, and ADME profiles, alongside therapeutic applications in cardiovascular diseases, cancer, and other conditions. It further examines bioavailability enhancement strategies, drug formulation, innovative delivery systems, and clinical trial evidence. Contributions from leading experts provide detailed insights into signaling pathways, molecular targets, and synthetic derivatives. Quercetin in Drug Discovery equips pharmacologists, medicinal chemists, and pharmaceutical scientists with critical information to advance research and drug development. By addressing bioavailability issues and regulatory considerations, this reference supports the translation of quercetin from bench to bedside, fostering innovation in natural product-based therapeutics.

  • Metabolic Reprogramming in Breast Cancer: A New Frontier in Therapy

    • 1st Edition
    • Volume 408
    • English
    Metabolic Reprogramming in Breast Cancer: A New Frontier in Therapy explores how altered metabolic pathways drive breast cancer progression, survival, and treatment resistance. The book highlights emerging insights into tumor metabolism and discusses how these discoveries may open new avenues for targeted and more effective therapies.

  • Biochemistry of Foods

    • 4th Edition
    • Michael N.A. Eskin + 2 more
    • English
    Biochemistry of Foods, 4th edition, continues to be the most comprehensive reference offering a broad overview of food biochemistry, food technology, human health and nutrition. This new edition outlines new developments in food biochemistry, such as metabolomics and the role of Artificial Intelligence in food innovation.Composed of 24 chapters, Section 1 deals with Biochemical Changes in Raw Foods, now including a new chapter on edible insects. Section 2 addresses changes due to food processing, including browning reactions such as the Maillard reaction, caramelization, and ascorbic acid oxidation. Additional chapters include baking and minimally processed foods. Section 3, Biochemistry of Food Spoilage, includes a new chapter on contaminants in foods. Section 4, on Health and Functional Foods, brings chapters on probiotics, prebiotics and symbiotics. The final section 5, on Biotechnology and Innovations in Foods, includes additional chapters on metabolomics, the role of AI in biochemistry of foods.Edited and written by a team of world-renowned experts, this impressively comprehensive reference continues to bridge the gap between introductory and highly specialized books dealing with aspects of food biochemistry for undergraduate and graduate students, researchers, and professionals in the fields of food science, horticulture, and nutrition.

  • Bioinformatics Essentials II

    From Multi‑omics to AI – Methods, Workflows, and Translational Applications
    • 1st Edition
    • Syed Mudasir Ahmad + 2 more
    • English
    Bioinformatics Essentials II, From Multi‑omics to AI – Methods, Workflows, and Translational Applications offers a comprehensive guide to modern bioinformatics, focusing on best-practice workflows for multi-omics data analysis and AI-assisted discovery. Designed for learners and early-career researchers, it bridges foundational knowledge with cutting-edge applications. The book covers experimental design, sequencing technologies, and core omics workflows including transcriptomics, proteomics, metabolomics, and epigenomics. Advanced chapters explore single-cell and spatial omics, multi-omics integration, AI/ML applications, and environmental bioinformatics.Each chapter includes learning objectives, worked examples, toolbox comparisons, and reproducible code. This resource empowers students, faculty, and applied researchers to confidently analyze complex datasets and translate findings into agriculture, health, and environmental solutions. Its modular structure and companion website enhance usability in both coursework and independent study.

  • Supercritical Fluid Technology for Food Processing

    Fundamentals and Applications
    • 1st Edition
    • Julian Martínez + 2 more
    • English
    Supercritical Fluid Technology for Food Processing: Fundamentals and Applications aims to bring a didactic approach to supercritical fluid technologies, considering the specific aspects of their use in food processing, and including issues that must be considered in a food industrial plant. The book's chapters cover fundamentals and then move through extraction, separation, adsorption, impregnation, drying, physical processing, particle formation, coprecipitation, reaction, and enzyme and microorganism inactivation. It concludes with a chapter on current practice and future challenges, as well as a look at project formulation for developing new food products.Supercritic... fluids have gained increasing attention in the scientific community and industries where their application can lead to valuable products by means of green and sustainable processes. Food processing is one of the greatest application fields of supercritical technology, which can help produce new and natural ingredients. It is increasingly applied by research groups in universities, including food engineering schools.

  • Adult Hydrocephalus and Disorders of CSF Dynamics

    • 1st Edition
    • Benjamin D. Elder + 1 more
    • English
    Adult Hydrocephalus and Disorders of CSF Dynamics reviews the pathophysiology, evaluation, differential diagnosis, management and treatment of adult hydrocephalus and disorders of cerebrospinal fluid (CSF). The introductory section begins with the anatomy and physiology of the cerebrospinal fluid system, with a review of adult hydrocephalus management, including longitudinal care and management of comorbidities. The following technical section devoted to shunt design and development, and then management of patients with idiopathic normal pressure hydrocephalus (iNPH). Coverage includes differential diagnosis and treatment of iNPH, as well as common presentations, neuroimaging, genetic studies, CSF biomarkers, and using artificial intelligence. Confirmatory testing discusses high volume lumbar punctures, lumbar drainage trials, and CSF infusion testing. Medical and surgical treatments are reviewed with expected functional outcomes. A subsequent section discusses secondary normal pressure hydrocephalus, caused by other etiologies such as hemorrhage, tumors, or infection, and covers longstanding overt ventriculomegaly (LOVA), management of adult patients who were shunted as children, and Chiari malformations. The book concludes with high and low pressure CSF dynamics disorders, including idiopathic intracranial hypertension and secondary intracranial hypertension, followed by a review of the medical, surgical, and ophthalmological management of these disorders.

  • Biofeedback and Pain Management

    A Clinical Guide
    • 1st Edition
    • Anu Kotay
    • English
    Biofeedback and Pain Management: A Clinical Guide provides a detailed understanding of the psychophysiology of chronic pain, biofeedback treatments, the realities of living life with chronic pain limitations, and the role of pain in our lives and society. The book covers evidence on the effective uses of biofeedback interventions for pain management, including protocols, as well as case-based examples and strategies practitioners can use in real-life settings. Sections define biofeedback, including illustrations that depict how biofeedback is a useful part of any pain management treatment plan, cover procedures based on evidence and case examples, and present the social context of chronic pain.

  • Fetal Metabolic Programming in Obesity and Diabetes

    From Mechanisms to Preventive Therapy
    • 1st Edition
    • Luis Sobrevia
    • English
    Fetal Metabolic Programming in Obesity and Diabetes: From Mechanisms to Preventive Therapy describes the consequences of cellular and molecular aspects of maternal obesity (before and during pregnancy), diabetes mellitus (pregestational and gestational), and gestational diabesity (i.e., women with pre-pregnancy obesity that developed GDM). The book covers the clinical aspects of mothers and children and the protocols for treating these diseases during pregnancy. Since the patients' clinical information correlates with metabolic parameters at a cellular and systemic level, it covers several pieces of evidence, addressing the pathophysiology of obesity and diabetes in pregnancy. This is an important resource for health professionals, researchers, and postdocs in obesity diabetes, as well as public health, physiology, biochemistry, cell biology, cell physiology, cell metabolism, and clinical and translational medicine.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Plant Development

    • 1st Edition
    • Volume 172
    • English
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.

  • Digestive Dynamics

    The Interplay Between Bariatric Surgery, Nutrition Strategies and Gut-Brain Axis
    • 1st Edition
    • Ahmed Hamad + 3 more
    • English
    Digestive Dynamics: The Interplay Between Bariatric Surgery, Food and Gut-Brain Axis offers an integrated perspective on the complex changes experienced by bariatric surgery patients and the vital role of nutrition in their recovery and long-term health. This comprehensive volume unites the latest advances in surgical physiology, metabolic adaptations, and gut microbiota with practical clinical nutrition strategies and innovative food science applications. Readers will find evidence-based guidelines on managing micronutrient deficiencies, dietary supplements, protein and fiber requirements, hydration, and food intolerances. The book also explores behavioral and psychological aspects, pharmacological considerations, and the role of exercise in holistic patient recovery. Special populations, including pregnant women, older adults, and pediatric patients, are addressed with tailored nutritional approaches. Digestive Dynamics: The Interplay Between Bariatric Surgery, Food and Gut-Brain Axis also address innovations in food formulation and emerging technologies, including artificial intelligence, and personalized nutrition. This is an indispensable resource for clinicians, researchers, and industry professionals dedicated to advancing bariatric care and nutrition science.

  • Health Impacts of Climate Change

    A Global Perspective
    • 1st Edition
    • Mohammad Hadi Dehghani + 2 more
    • English
    Health Impacts of Climate Change: A Global Perspective confronts the most urgent reality of our time: the climate crisis is, at its core, a health crisis. Drawing from the latest research in climate science, public health, and policy, this book offers a comprehensive, interdisciplinary look at how global warming is already endangering lives—and what can be done to protect them. Readers will gain a deep understanding of direct health threats like heatstroke, air pollution, and disaster-related trauma, as well as the less visible dangers: rising zoonotic diseases, crop failures leading to malnutrition, and mental health challenges driven by climate-induced displacement.What sets this book apart is its unwavering focus on equity. It explores how climate change disproportionately impacts the most vulnerable—low-incom... communities, people in the Global South, and marginalized groups—who contribute the least to global emissions but bear the brunt of the damage. Through case studies, personal narratives, and policy analysis, the book amplifies frontline experiences and calls for climate justice as an essential part of any effective health response. From practical strategies for healthcare professionals to frameworks for policymakers, this book empowers a wide range of readers—from students and researchers to community leaders and concerned citizens.

  • Baleen Whales

    Ridgway and Harrison's Handbook of Marine Mammals: Volume 4
    • 1st Edition
    • Thomas Allen Jefferson
    • English
    Some of the world's most beautiful, intelligent, and highly adapted mammals inhabit our seas and oceans and have stirred the human imagination for many centuries. As our knowledge of marine mammals grows, the need exists for a reliable and complete reference to the ecology and biology of these fascinating creatures. To address this need, the Handbook of Marine Mammals series has been founded. Scientists, conservationists, and informed laypersons alike will be able to find definitive reviews of all the world's living whales, dolphins, porpoises, seals, sea lions, sea cows, and marine otters and bears. Seven volumes cover all the living species of marine mammals.This fourth volume in the series, Baleen Whales, consists of species review chapters written by leading global experts on whale species that have baleen plates instead of teeth. Each chapter includes a description of the species, followed by sections on distribution and abundance, anatomy, physiology, behavior, ecology, reproduction, parasites and diseases, and the impacts of human activities on the species.

  • Human Reproduction

    From basics to Biotechnology
    • 1st Edition
    • Marc yeste
    • English
    Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.

  • Bacterial Infections of the Central Nervous System

    • 1st Edition
    • Karen L. Roos + 1 more
    • English
    "Bacterial Infections of the Central Nervous System" consolidates recent discoveries and best practices on diagnosis and treating infection to minimize morbidity and mortality. The book discusses advancements in neuroimaging techniques, diagnostic studies performed on cerebrospinal fluid, adjunctive therapy, and antimicrobial therapy. Beginning with pathogenesis and pathophysiology of bacterial CNS infections, the book reviews when to suspect a bacterial infection of the central nervous system. The majority of the chapters review specific disease entities, including meningitis, focal CNS infections (e. g., brain abscess, subdural empyema and epidural abscess), CNS diseases caused by selected infectious pathogens (Mycobacteria, Rickettsiae, Anaplasmataceae, Treponema pallidum, Borrelia burgdorferi and other Borrelia species), the neurological complications of infective endocarditis, suppurative venous sinus thrombosis, infections in the neurosurgical patient, bacterial etiologies of movement disorders, Guillain-Barre syndrome, toxin-mediated syndromes of the nervous system and infectious encephalopathy.

  • Cell Death Part H

    • 1st Edition
    • Volume 215
    • English
    Cell Death Part H presents current methods and experimental approaches for studying the mechanisms, regulation, and biological significance of cell death. The volume covers advanced protocols and model systems used to investigate diverse cell death pathways in health and disease, making it a valuable resource for researchers in cell biology, molecular biology, and biomedical science.

  • Recent Advances in Food Enzymes

    Innovations and Applications
    • 1st Edition
    • Vijay Kumar + 3 more
    • English
    Recent Advances in Food Enzymes: Innovations and Applications presents the latest developments in enzyme applications across food science, biotechnology, and biochemistry. This essential resource is designed for researchers and professionals, offering in-depth insights into how food enzymes can optimize processes, enhance product quality, and drive innovation within the food industry. Covering a broad spectrum of topics—from fundamental biochemical concepts and AI-driven enzyme discovery to practical applications in dairy, meat, and beverage production—this book serves as a vital reference for those seeking to leverage enzyme technology for improved efficiency and effectiveness in food product development, nutraceuticals and bioprocessing.In addition to addressing the technical aspects of enzyme application, this book emphasizes sustainability and highlights the role of enzymes in waste management and eco-friendly practices, making it invaluable for sustainability advocates. Case studies, expert insights, and technology advancements equips readers with the knowledge needed to navigate the challenges and opportunities presented by enzyme technologies in today's evolving food landscape.

  • Advances in Medical Simulation

    Techniques, Applications and Innovations
    • 1st Edition
    • Noor Zaman Jhanjhi + 2 more
    • English
    Advances in Medical Simulation: Techniques, Applications, and Innovations explores cutting-edge developments in medical simulation, focusing on its transformative role in medical education, training, and patient care. The book examines various simulation techniques, including virtual and augmented reality, high-fidelity mannequins, and task trainers, showcasing their applications in surgical training, clinical diagnostics, and emergency response. Sections provide an in-depth discussion of the challenges and future directions in medical simulation, highlighting innovations such as robotics and artificial intelligence. By addressing gaps in existing literature, this book offers a comprehensive understanding of how advanced simulation techniques can enhance healthcare professionals' skills and competencies.For the academic audience, this book serves as a vital resource that bridges research and practical applications in clinical settings. It identifies trends and opportunities for future innovation, ultimately aiming to reduce medical errors and improve patient safety through effective simulation-based practices.

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