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Books in Life sciences

  • Dendrimer-Based Nanotherapeutics

    • 1st Edition
    • April 14, 2021
    • Prashant Kesharwani
    • English
    Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields.

  • Machine Learning and the Internet of Medical Things in Healthcare

    • 1st Edition
    • April 14, 2021
    • Krishna Kant Singh + 3 more
    • English
    Machine Learning and the Internet of Medical Things in Healthcare discusses the applications and challenges of machine learning for healthcare applications. The book provides a platform for presenting machine learning-enabled healthcare techniques and offers a mathematical and conceptual background of the latest technology. It describes machine learning techniques along with the emerging platform of the Internet of Medical Things used by practitioners and researchers worldwide. The book includes deep feed forward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology. It also presents the concepts of the Internet of Things, the set of technologies that develops traditional devices into smart devices. Finally, the book offers research perspectives, covering the convergence of machine learning and IoT. It also presents the application of these technologies in the development of healthcare frameworks.

  • Autophagy and Senescence in Cancer Therapy

    • 1st Edition
    • Volume 150
    • April 13, 2021
    • English
    Advances in Cancer Research, Volume 150, the latest release in this ongoing series, covers the relationship(s) between autophagy and senescence, how they are defined, and the influence of these cellular responses on tumor dormancy and disease recurrence. Specific sections in this new release include Autophagy and senescence, converging roles in pathophysiology, Cellular senescence and tumor promotion: role of the unfolded protein response, autophagy and senescence in cancer stem cells, Targeting the stress support network regulated by autophagy and senescence for cancer treatment, Autophagy and PTEN in DNA damage-induced senescence, mTOR as a senescence manipulation target: A forked road, and more.

  • Pituitary Tumors

    A Comprehensive and Interdisciplinary Approach
    • 1st Edition
    • April 11, 2021
    • Jürgen Honegger + 2 more
    • English
    Pituitary Tumors: A Comprehensive and Interdisciplinary Approach provides the latest information on preclinical issues, diagnostic procedures, treatment options and post-treatment care for patients with pituitary tumors. The book includes basic and advanced knowledge for a broad audience, including physicians, endocrinologists, neurosurgeons, neuro-radiologists, neuro-ophthalmologis... neuro-pathologists, oncologists, radiotherapists and researchers who are investigating pituitary tumors. Readers will find the latest research surrounding progress on uncoding the molecular mechanisms involved in tumor genesis. In addition, standard treatment modalities, including surgery, medical treatment and radiosurgery are explored.

  • Global Perspectives on Astaxanthin

    From Industrial Production to Food, Health, and Pharmaceutical Applications
    • 1st Edition
    • April 9, 2021
    • Gokare A. Ravishankar + 1 more
    • English
    Global Perspectives on Astaxanthin: From Industrial Production to Food, Health, and Pharmaceutical Applications explores the range of practical applications for this molecule, focusing on nutraceutical, pharmaceutical and cosmeceutical products, along with food and feed. This volume brings together the most relevant research, background and future thinking on astaxanthin, focusing on its health benefits. Chapters cover phytopharmaceuticals... industrial production, feeds, downstream processing, regulations, products, color, pigment, cosmetics, bioactive compounds, relationships to other carotenoids, and skin care. The detailed information on its production, processing, utilization and future applications will be of particular use to academic and industry researchers in pharmaceutical sciences, pharmacology and nutrition.

  • Epidemiology of Brain and Spinal Tumors

    • 1st Edition
    • April 9, 2021
    • Jahangir Moini + 2 more
    • English
    Epidemiology of Brain and Spinal Tumors provides a single volume resource on imaging methods and neuroepidemiology of both brain and spinal tumors. The book covers a variety of imaging techniques, including computed tomography (CT), MRI, positron emission tomography (PET), and other laboratory tests used in diagnosis and treatment. Detailed epidemiology, various imaging methods, and clinical considerations of tumors of the CNS make this an ideal reference for users who will also find diverse information about structures and functions, cytology, epidemiology (including molecular epidemiology), diagnosis and treatment. This book is appropriate for neuroscience researchers, medical professionals and anyone interested in a complete guide to visualizing and understanding CNS tumors.

  • Memory Loss, Alzheimer's Disease and Dementia

    A Practical Guide for Clinicians
    • 3rd Edition
    • April 9, 2021
    • Andrew E. Budson + 1 more
    • English
    **Selected for Doody’s Core Titles® 2024 with "Essential Purchase" designation in Geriatrics**With a focus on the practical, day-to-day tools needed by neurologists, psychiatrists, geriatricians, and others who work with the elderly, Memory Loss, Alzheimer's Disease and Dementia, 3rd Edition, is an indispensable, easy-to-read resource in this growing area. Clinical experts Drs. Andrew Budson and Paul Solomon cover the essentials of physical and cognitive examinations and laboratory and imaging studies for dementia and related illnesses, giving you the guidance you need to make accurate diagnosis and treatment decisions with confidence.

  • Handbook of Computational Intelligence in Biomedical Engineering and Healthcare

    • 1st Edition
    • April 8, 2021
    • Janmenjoy Nayak + 3 more
    • English
    Handbook of Computational Intelligence in Biomedical Engineering and Healthcare helps readers analyze and conduct advanced research in specialty healthcare applications surrounding oncology, genomics and genetic data, ontologies construction, bio-memetic systems, biomedical electronics, protein structure prediction, and biomedical data analysis. The book provides the reader with a comprehensive guide to advanced computational intelligence, spanning deep learning, fuzzy logic, connectionist systems, evolutionary computation, cellular automata, self-organizing systems, soft computing, and hybrid intelligent systems in biomedical and healthcare applications. Sections focus on important biomedical engineering applications, including biosensors, enzyme immobilization techniques, immuno-assays, and nanomaterials for biosensors and other biomedical techniques. Other sections cover gene-based solutions and applications through computational intelligence techniques and the impact of nonlinear/unstructur... data on experimental analysis.

  • Pragmatic Randomized Clinical Trials

    Using Primary Data Collection and Electronic Health Records
    • 1st Edition
    • April 8, 2021
    • Cynthia J. Girman + 1 more
    • English
    Pragmatic Randomized Clinical Trials Using Primary Data Collection and Electronic Health Records addresses the practical aspects and challenges of the design, implementation, and dissemination of pragmatic randomized trials, also sometimes referred to as practical or hybrid randomized trials. While less restrictive and more generalizable than traditional randomized controlled trials, such trials have specific challenges which are addressed in this book. The book contains chapters encompassing common designs along with advantages and limitations of such designs, analytic aspects in planning trials and estimating sample size, and how to use patient partners to help design and operationalize pragmatic randomized trials. Pragmatic trials conducted using primary data collection and trials embedded in electronic health records - including electronic medical records and administrative insurance claims - are addressed.This comprehensive resource is valuable not only for pharmacoepidemiologi... biostatisticians and clinical researchers, but also across the biomedical field for those who are interested in applying pragmatic randomized clinical trials in their research.

  • Metal and Nutrient Transporters in Abiotic Stress

    • 1st Edition
    • April 8, 2021
    • Aryadeep Roychoudhury + 2 more
    • English
    Metal and Nutrient Transporters in Abiotic Stress focuses on the different forms of environmental stress related to heavy metal, metalloid and nutrient deficiency that have the potential to inflict major damages to crop plants, leading to a massive decrease in crop yield and productivity. The book presents the current state of knowledge of the biochemical and molecular regulation of several classes of membrane transporters related to the uptake of metals/metalloids and nutrient elements during different stresses and their probable mechanisms of operation in plant stress tolerance. Metal and Nutrient Transporters in Abiotic Stress provides a comprehensive discussion that will help in mitigating multiple forms of stresses utilizing transporter proteins. Edited by leading experts and written by a global team of knowledgeable contributors, this book will further stimulate research in the field of transporter proteins and will foster further interests for researchers, academicians and scientists worldwide. It is complimented by its companion book titled Transporters and Plant Osmotic Stress.

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