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Elsevier

Pediatric Reference Intervals

  • 8th Edition - November 13, 2020
  • Latest edition
  • Authors: Edward C.C. Wong, Carlo Brugnara, Joely Straseski, Mark Kellogg, Khosrow Adeli
  • Language: English

Pediatric Reference Intervals, Eighth Edition, is a must-have for clinical chemists, hematologists, pathologists, endocrinologists and pediatricians. This trusted source enhances… Read more

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Description

Pediatric Reference Intervals, Eighth Edition, is a must-have for clinical chemists, hematologists, pathologists, endocrinologists and pediatricians. This trusted source enhances interpretation of patient results, allows comparison of test results using different methods, and helps optimize patient care. This updated edition is a valuable reference, providing instant and accurate reference intervals for over 250 chemistry and hematology analytes in an alphabetized, user-friendly format. Changes to this edition include Age- and Sex-Related Reference Ranges, Methodologies, Type of Specimen, References, Statistical Basis and Population Sources.

Key features

  • Provides the reference intervals for a wide variety of analytes for children, from neonates to adolescents to young adults
  • Enhances interpretation of patient results, allows comparison of text results using different methods, and helps optimize patient care
  • Trusted, vetted source that’s been in the market for decades

Readership

Laboratory pathologists, clinical chemists, hematologists, pathologists, endocrinologists, and pediatricians

Table of contents

Foreword

Preface

Introduction

1 Chemistry tests

Acylcarnitine Profile

Adiponectin

Adrenocorticotropic Hormone (ACTH)

Alanine Aminotransferase (ALT, SGPT)

Albumin

Aldolase

Aldosterone

Alkaline Phosphatase (ALP)

Alkaline Phosphatase, Bone-Specific

Alpha-1 Antitrypsin

Alpha-Fetoprotein (AFP)

Amino Acids, Plasma

Alanine

b-Alanine

a-Aminoadipic Acid

a-Aminobutyric Acid

g-Aminobutyric Acid

b-Aminoisobutyric Acid

Anserine

Arginine

Asparagine

Aspartate

Carnosine

Citrulline

Cystathionine

Cystine

Ethanolalanine

Glutamate

Glutamine

Glycine

Histidine

Homocystine

Hydroxylysine

Hydroxyproline

Isoleucine

Leucine

Lysine

Methionine

1-Methyl-histidine

3-Methyl-histidine

Ornithine

Phenylalanine

Phosphoethanolamine

Phosphoserine

Proline

Sarcosine

Serine

Taurine

Threonine

Tryptophan

Tyrosine

Valine

Amino Acids, Urine

Alanine

b-Alanine

a-Aminoadipic Acid

a-Aminobutyric Acid

g-Aminobutyric Acid

b-Aminoisobutyric Acid

Anserine

Arginine

Asparagine

Aspartate

Carnosine

Citrulline

Cystathionine

Cystine

Ethanolamine

Glutamate

Glutamine

Glycine

Histidine

Homocystine

Hydroxylysine

Hydroxyproline

Isoleucine

Leucine

Lysine

Methionine

1-Methyl-histidine

3-Methyl-histidine

Ornithine

Phenylalanine

Phosphoethanolamine

Phosphoserine

Proline

Sarcosine

Serine

Taurine

Threonine

Tryptophan

Tyrosine

Valine

Amylase

Amylase, Pancreatic

Androstenedione

Anti-Mu¨llerian Hormone (AMH)

Antistreptolysin O (ASO)

Apolipoprotein A

Apolipoprotein B

Aspartate Aminotransferase (AST, SGOT)

b-Hydroxybutyrate/3-Hydroxybutyrate

b2-Microglobulin

Base Excess

Bile Acids, Total 3a-Hydroxy Bile Acids

Bilirubin, Conjugated

Bilirubin, Total

Brain Natriuretic Peptide (BNP)

N-Terminal Pro-Brain Natiuretic Peptide (NT-proBNP)

C-Peptide

C-Reactive Protein (CRP)

C-Telopeptide

Calcium, Serum/Plasma

Calcium, Urine

Carbon Dioxide (CO2)

Carboxyhemoglobin (COHb)

Carnitine, Total

Ceruloplasmin

Chloride

Cholesterol

Cholinesterase Dibucaine Number

Citrate, Urine

Creatine KinaseeMB isoform (CK-MB)

Complement FractiondC3c

Complement FractiondC4

Copper

Corticosterone

Cortisol, Serum

Cortisol, Urinary Free

Creatine Kinase (CK)

Creatinine

Cystatin C

Dehydroepiandrosterone (DHEA)

Dehydroepiandrosterone Sulfate (DHEAS)

Deoxycorticosterone (DOC)

11-Deoxycortisol (Compound S)

Dihydrotestosterone (DHT)

Dopamine, Urine

Epinephrine, Serum

Epinephrine, Urine

Estradiol

Estrone

Ferritin

Folate

Follicle Stimulating Hormone (FSH)

Free Fatty Acids

Gamma-Glutamyltransferase (GGT)

Glucose

Growth Hormone

Haptoglobin

High-Density Lipoprotein Cholesterol (HDL-C)

Homocysteine, Total

Homovanillic Acid (HVA; 4-Hydroxy-3-Methoxyphenylacetic Acid), Urine

Beta Human Chorionic Gonadotropin (beta-hCG)

17-hydroxypregnenolone

17a-Hydroxyprogesterone (17a-OHP)

lmmunoglobulin A (IgA)

Immunoglobulin E (IgE)

Immunoglobulin G (IgG)

Immunoglobulin G1 (IgG1)

Immunoglobulin G2 (IgG2)

Immunoglobulin G3 (IgG3)

Immunoglobulin G4 (IgG4)

Immunoglobulin M (IgM)

Insulin

Insulin-like Growth Factor Binding Protein-3 (IGFBP-3)

Insulin-like Growth Factor-1 (IGF-1)

Iron

Total Iron Binding Capacity

Lactate, Serum/Plasma

Lactate, CSF

Lactate Dehydrogenase

Leptin

Lipase

Lipoprotein (a)

Low-Density Lipoprotein-Cholesterol (LDL-C)

Luteinizing Hormone (LH)

Magnesium

Metanephrine, Urine

Mucopolysaccharides, Urine

Myoglobin

N-Telopeptide (NTx), Urine

Norepinephrine/Noradrenaline, Plasma

Norepinephrine/Noradrenaline, Urine

Normetanephrine, Urine

Osmolality, Urine

Osteocalcin

Oxalate, Urine

Oxygen Saturation

Parathyroid Hormone (PTH)

Phosphorus, Serum/Plasma

Phosphorus, Urine

Potassium

Prealbumin (Transthyretin)

Pregnenolone

Procalcitonin

Progesterone

Prolactin

Protein, Total

Protein, CSF

Rheumatoid Factor

Selenium

Sex Hormone Binding Globulin (SHBG)

Sodium, Serum

Sodium, Urine

Soluble Transferrin Receptor

Testosterone

Testosterone, Free

Thyroid Stimulating Hormone (TSH)

Thyroxine (T4)

Thyroxine-Binding Globulin (TBG)

Thyroxine, Free (Free T4)

Transferrin

Transferrin Saturation

Triglycerides

Triiodothyronine (T3)

Triiodothyronine, Free (Free 13)

Troponin I

Troponin T

Urea Nitrogen

Uric Acid

Vanillylmandelic Acid (VMA; 4-Hydroxy-3-Methoxymandelic Acid), Urine

Vitamin A

Vitamin B12

1,25 Dihydroxy Vitamin D

25-Hydroxy Vitamin D

206 Vitamin E (a-Tocopherol)

Zinc

2 Hematology tests

Basophil Count, Absolute

Basophil Count, Relative

Eosinophil Count, Absolute

Eosinophil Count, Relative

Hematocrit

Hemoglobin

Immature Granulocyte Count (IG), Absolute

Immature Granulocyte Count (IG), Relative

Immature Platelet Count (IPC)

Immature Platelet Fraction (IPF)

Lymphocyte Count, Absolute

Lymphocyte Count, Relative

Mean Corpuscular Hemoglobin (MCH)

Mean Corpuscular Hemoglobin Concentration (MCHC)

Mean Corpuscular Volume (MCV)

Mean Platelet Volume (MPV)

Monocyte Count, Absolute

Monocyte Count, Relative

Neutrophil Count, Absolute

Neutrophil Count, Relative

Nucleated Red Blood Cell Count (Absolute)

Platelet Count

RBC Count

Red Cell Distribution Width (RDW)

Reticulocyte Count, Absolute

Reticulocyte Count, Relative

Reticulocyte Hemoglobin Content

WBC Count

Additional Reading

3 Coagulation tests

Activated Partial Thromboplastin Time

ADAMTS13 Activity

Alpha 2- Antiplasmin

Antithrombin Activity

D-Dimer

Factor II

Factor V

Factor VII

Factor VIII

Factor IX

Factor X

Factor XI

Factor XII

Factor XIII

Fibrinogen Activity, Clauss

Plasminogen

Protein C Activity

Protein C Antigen

Protein S Activity

Protein S Antigen, Free

Protein S Antigen, Total

Prothrombin Time

TEG Parameters, Kaolin-Activated (Citrated Whole Blood)

TEG Parameters, Kaolin-Activated (Whole Blood Only)

Thrombin Clotting Time

Tissue Factor Protein Inhibitor, Total

Von Willebrand Factor Activity

Von Willebrand Factor Antigen

Von Willebrand Factor: Collagen Binding

Additional Reading

Review quotes

"If you perform laboratory testing for pediatric populations and consult with pediatricians, get this book now."—Doody

Product details

  • Edition: 8
  • Latest edition
  • Published: November 13, 2020
  • Language: English

About the authors

EW

Edward C.C. Wong

Edward Wong FCAP is Medical Director, Coagulation, Quest Diagnostics Nichols Institute; Adjunct Associate Professor in Pediatrics and Pathology, George Washington School of Medicine and Health Sciences, Clinical Consultant at Children’s National Hospital in the Divisions of Pathology and Laboratory Medicine; and Hematology, Washington DC, USA
Affiliations and expertise
Medical Director, Coagulation/Blood Bank, Quest Diagnostics/Nichols Institute, Chantilly, VA, USA

CB

Carlo Brugnara

Carlo Brugnara is the Medical Director of Boston Children’s Hospital & Department of Pathology, Harvard Medical School
Affiliations and expertise
Director, Hematology Lab Professor of Pathology, Harvard Medical School, Boston, MA, USA

JS

Joely Straseski

Joely Straseski DABCC works at University of Utah in the ARUP Laboratories, Salt Lake City, UT
Affiliations and expertise
PhD, DABCC, University of Utah, ARUP Laboratories, Salt Lake City, UT

MK

Mark Kellogg

Dr. Mark David Kellogg, Assistant Professor of Pathology at Harvard Medical School and Associate Director of Chemistry in the Department of Laboratory Medicine at Boston Children’s Hospital. With a PhD in Biology from the University of Notre Dame and a fellowship in Clinical Chemistry at Boston Children’s Hospital, Dr. Kellogg has over three decades of experience in clinical laboratory science, research, and education. He has held leadership roles including Co-Director of the Clinical Chemistry Fellowship Program and Director of Quality Programs at Boston Children’s Hospital, as well as Director of Clinical Laboratory at Claritas Genomics. Dr. Kellogg is active in professional organizations such as the American Association of Clinical Chemistry, Clinical Laboratory Standards Institute, and Academy of Clinical Laboratory Physicians and Scientists. He has published extensively on biochemical analyte measurement, clinical assay validation, and biomarker development. He is mentor, leading clinical chemistry training contributing to national and international laboratory standards.
Affiliations and expertise
PhD, DABCC, Department of Laboratory Medicine, Boston Children’s Hospital and the Department of Pathology, Harvard Medical School, Boston, MA

KA

Khosrow Adeli

Dr. Khosrow Adeli is a distinguished leader in clinical biochemistry and pediatric laboratory medicine, serving as Division Head at SickKids since 1988 and Director of its Point of Care Testing Program since 2001. He is Vice Chair of Quality at the University of Toronto’s Laboratory Medicine and Pathobiology department and served as President of the International Federation of Clinical Chemistry & Laboratory Medicine (IFCC) from 2020 to 2023. His research focuses on the pathophysiology of obesity, metabolic syndrome, and type 2 diabetes, particularly neuroendocrine regulation of lipoprotein metabolism via the gut-brain-liver axis. He leads the CALIPER project, establishing pediatric reference intervals widely used in clinical practice globally. Dr. Adeli has published over 600 articles and abstracts, and his work has been recognized with multiple prestigious awards for research, innovation, and teaching excellence.
Affiliations and expertise
PhD, University of Toronto, Departments of Biochemistry and Laboratory Medicine & Pathology, Toronto, Ontario, Canada

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