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Books in Life sciences

    • Design and Applications of Cell-Free Systems Part A

      • 1st Edition
      • Volume 218
      • English
      Design and applications of cell-free systems –Part A represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE). CFS requires a core molecular machinery including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins. It has the potential to overcome loopholes in the current in vivo production systems and it is promising tool in both basic and applied scientific research. It facilitates a simplified organization of desired experiments with a variety of reaction conditions, making CFS a powerful tool in biological and translational science research.This volume offers wide range of topics on different aspects of cell free systems design and their applications. It covers introduction to applications of cell-free systems, protocol for cell free design, transcription and translation, computational biology, artificial intelligence, automation and robotics for cell free systems, cell free for biosensor, low cost diagnostics, cell free based high throughput screening, biodesign and incorporation of non-natural amino acids into proteins. This volume helps students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand cell-free systems and their applications in many areas.
    • Machine Learning in MRI

      From Methods to Clinical Translation
      • 1st Edition
      • Volume 13
      • Thomas Kuestner + 3 more
      • English
      Machine Learning in MRI: From Methods to Clinical Translation, Volume Thirteen in theAdvances in Magnetic Resonance Technology and Applications series presents state-of-the-art machine learning methods in magnetic resonance imaging that can shape and impact the future of patient treatment and planning. Common methods and strategies along the processing chain of data acquisition, image reconstruction, image post-processing, and image analysis of these imaging modalities are presented and illustrated. The book focuses on applications and anatomies for which machine learning methods can bring, or have already brought. Ideas and concepts on how processing could be harmonized and used to provide deployable frameworks that integrate into the clinical workflows are also considered.Pitfalls and current limitations are discussed in the context of how they could be overcome to cater for clinical needs, making this an ideal reference for medical imaging researchers, industry scientists and engineers, advanced undergraduate and graduate students, and clinicians. By giving an interdisciplinary presentation and discussion on the obstacles and possible solutions for the clinical translation of machine learning methods, this book enables the evolution of machine learning in medical imaging for the next decade.
    • Genetic Regulation of Immune Response Pathways

      • 1st Edition
      • Volume 115
      • English
      Genetic Regulation of Immune Response Pathways, Volume 115 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Chapters explore the genetic regulation of immune cells upon activation, IFN response regulation during viral infections, and the role of noncoding RNAs—including lncRNAs and ncRNAs—in immune regulation and inflammation. Additional sections examine the JAK-STAT signaling pathway in inflammatory and autoimmune diseases as a potential therapeutic target, long noncoding RNAs as key regulators of autoimmunity, and the importance of appropriate cytokine expression in maintaining immune response homeostasis.Together... these contributions provide valuable insights into the molecular and genetic mechanisms underlying immune-mediated processes.
    • Aflatoxin Management in Crops

      Challenges and Opportunities
      • 1st Edition
      • Sajad Majeed Zargar + 3 more
      • English
      Aflatoxin Management in Crops: Challenges and Opportunities provides a comprehensive look at current insights into aflatoxin contamination in agricultural crops and its effect on human health on global level. With insights from around the globe, it presents the latest advances in the understanding of the contamination and management strategies for aflatoxins in cereals, millets, oilseed, fruits, vegetables, and dairy products. Aflatoxin contamination in crops is a global threat that compromises the safety of food, feed, and also influence the agricultural economy and crop-dependent small scale industries. Crops can be contaminated during the process of harvesting, storing, and transporting by the fungi and leads to the productions of several mycotoxins. Aflatoxin can be extremely harmful if consumed, being linked to cancer-, immune-, and nutritionally related diseases. Aflatoxin Management in Crops: Challenges and Opportunities includes the biology of fungi and the chemistry behind the toxicity level of different aflatoxin strains as well as advances in detection techniques and management strategies. It concludes by exploring the different effects of aflatoxin on human health and regulatory laws to control its contamination.
    • AI and Data Science in Healthcare 5.0

      • 1st Edition
      • Olfa Boubaker
      • English
      AI and Data Science in Healthcare 5.0 delves into the innovative developments in Healthcare 5.0, focusing on smart medical robots, devices, and connected hospitals. It explores the role of robotics in modern healthcare, including advanced wearables enhanced by deep learning. The volume also addresses the integration of blockchain technology, IoT, and cloud computing in healthcare, emphasizing real-time applications in precision healthcare. The discussion extends to energy optimization in smart hospitals, federated learning for IoMT networks, and advanced patient monitoring systems.The volume concludes with an overview of the future opportunities and challenges in Healthcare 5.0.
    • How Sex and Gender Impact Clinical Practice

      An Evidence-Based Guide to Patient Care
      • 2nd Edition
      • Marjorie R. Jenkins + 1 more
      • English
      How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, is an essential resource for primary care clinicians seeking to integrate sex and gender differences into their practice. This edition emphasizes the unique framework that assists practitioners in providing personalized care. It aligns sex and gender medicine with precision medicine, helping healthcare providers attract patients who value clinicians that understand the nuances of sex and gender in healthcare.How Sex and Gender Impact Clinical Practice: An Evidence-Based Guide to Patient Care, Second Edition, includes updates on the evidence-based information on disease prevalence, diagnosis, testing, and treatment, as well as a new chapter on the sex and gender aspects of pain. Each chapter reflects how sex and gender impact disease presentation, physical examination, testing, treatment, and clinical decision-making.
    • Emerging Trends in Phytotherapy of Cancer

      • 1st Edition
      • Mahendra Rai + 1 more
      • English
      Emerging Trends in Phytotherapy of Cancer is an essential reference that explores the multifaceted role of medicinal plants in combating cancer. The book covers a broad range of interconnected topics including ethnomedicinal plants used in cancer by tribes and aboriginals, herbs used in Ayurvedic medicine for cancer, integrated approaches of modern and conventional drugs, anti-cancerous secondary metabolites, plant-based anticancer drugs approved by FDA and WHO, toxicity to humans, and the role of emerging technologies such as the applications of nanotechnology and artificial intelligence. The contents are divided into six parts. Part one opens with an introductory chapter, followed by the different combinations of plant-based drugs and modern medicine for cancer treatment, and recent developments in cancer research. Part two discusses the ethnomedicinal uses of plants in cancer and the role of Ayurvedic herbal medicines in cancer. Part three incorporates the role of secondary metabolites in cancer treatment. Part four elaborates on the plant-based drugs recommended by FDA/WHO. Part five concerns the human phytotoxicity of secondary metabolites, and part six describes the role of emerging nanotechnologies and artificial intelligence in phytotherapy drug delivery and treatment. Targeted at researchers, healthcare professionals, and advanced students in related fields, this book provides technical and in-depth knowledge, contributing to ongoing advancements in cancer treatment. It uniquely integrates ethnomedicinal therapies with modern technologies, offering a comprehensive overview of the research into phytomedicinal cancer therapies.
    • Engineered Nanomaterials for Agricultural Sustainability

      Current Status, Methods, and Future Strategies
      • 1st Edition
      • Sanghamitra Majumdar + 1 more
      • English
      Engineered Nanomaterials for Agricultural Sustainability: Current Status, Methods, and Future Strategies offers an in-depth exploration of how nanotechnology is transforming agriculture by enhancing crop productivity and environmental sustainability. The book addresses the bottleneck between the development and the implementation of nanotechnology in agriculture, focusing on the knowledge gaps related to environmental fate, standardization of characterization methods, mechanism of biological interaction, safety concerns, and the lack of consensus in regulatory guidelines.A volume in the Nanomaterial-Plant Interactions series, Engineered Nanomaterials for Agricultural Sustainability covers the design and application of nanomaterials for critical agricultural applications, such as nano-fertilizers, nano-pesticides, soil remediation, and nutrient management. It discusses key considerations regarding the fate and transport of the nano-enabled agrochemicals for their safe and effective commercialization. Subject matter experts provide comprehensive insights into the characterization techniques for studying nanomaterials in an agricultural context and advancements in understanding their mechanism of action and toxicity using multi-omics tools. The chapters present the latest research alongside regulatory challenges, offering a structured approach that enables readers to design nanomaterials for specific agricultural applications while avoiding undesirable impacts.With a strong focus on sustainability, this volume provides a roadmap for responsible and effective implementation of nanotechnology in agriculture. It will be a go-to reference for those looking to harness nanomaterials to enhance agricultural productivity and ensure food security.
    • Nanotherapeutics Combating Microbial Infections and Antimicrobial Resistance

      Volume 2 - Nanotheranostics, Microbial Infections, and Antimicrobial Resistance
      • 1st Edition
      • Divakar Sharma + 1 more
      • English
      Nanotherapeutics Combating Microbial Infections and Antimicrobial Resistance: Volume Two, Nanotheranostics, Microbial Infections, and Antimicrobial Resistance delves into the innovative use of nanotechnology to tackle antimicrobial resistance (AMR) and treat bacterial infections. The second volume of this series showcases cutting-edge nano-based solutions developed to overcome multi-drug resistant pathogens, offering insights from leading experts. This book is an essential resource for researchers, academics, students, industry professionals, and clinicians in fields related to microbiology, infectious diseases, and nanotechnology, providing a comprehensive overview of the latest advancements in the fight against bacterial infections.Other noteworthy highlights of this book include contributions from experts, informative references, and emerging technologies aimed at both treating and preventing the progression of bacterial infections. This volume is particularly valuable for those interested in the intersection of nanotechnology and healthcare.
    • Fundamentals of Space Medicine and Clinical Technology

      • 1st Edition
      • Ethan Waisberg + 2 more
      • English
      Fundamentals of Space Medicine and Clinical Technology is a comprehensive guide that delves into the advanced technologies utilized in space medicine today. The book is structured into three sections: an introduction to the physiology of space medicine, a detailed overview of various space medicine technologies, and the application of these technologies on Earth. Authored by leading experts in the field, it aims to bridge the gap between space medicine physiology and technological advancements, offering valuable insights. Additionally, the book serves as a useful resource for doctors, engineers, commercial industries, and governments, highlighting the significance of translational applications of space medicine technologies.This is a pivotal read for anyone interested in the intersection of space exploration and medical science.