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Elsevier

Books in Life sciences

  • The Future of Pharma Across All Sectors in the Artificial Intelligence Era

    • 1st Edition
    • Miltiadis Lytras + 5 more
    • English
    The Future of Pharma Across All Sectors in the Artificial Intelligence Era offers a thorough examination of the pharmaceutical industry's current landscape, highlighting the myriad challenges, opportunities, and trends that are poised to shape its future. Edited by experts, this book delves into transformative technological advancements, including artificial intelligence, machine learning, big data analytics, and blockchain. These technologies are redefining pharmaceutical research, development, and commercialization, making precision medicine and personalized therapies a reality, while integrating genomic medicine into the pharmaceutical value chain.Additionally, the book addresses educational implications for academic curricula, emphasizing the need for digital transformation in healthcare delivery models. It scrutinizes regulatory trends and compliance, offering insights into navigating complex landscapes to ensure product quality and safety. The book emphasizes the pharmaceutical industry's role in tackling infectious diseases and health disparities, promoting health equity through innovative drug development and access initiatives. Future trends and predictions are speculated upon, considering demographic shifts and evolving healthcare needs, while market dynamics and commercial strategies are analyzed to equip pharmaceutical companies with practical recommendations for navigating competitive landscapes.

  • Microbial Technologies for Sustainable Waste Management

    • 1st Edition
    • Rajneesh Kumar + 2 more
    • English
    Microbial Technologies for Sustainable Waste Management explores advanced waste management through microbial processes. The book investigates the current limitations of traditional waste treatment and the potential for microbial cell factories in bringing innovative solutions to this field. Beginning with an introduction to the role of microbes in waste management, it examines global case studies demonstrating success stories in microbial waste treatment and microbial innovations for biotechnological applications in waste conversion. Concluding chapters focus on microbial pathways for anaerobic digestion, hydrolysis, and fermentation, and microbial technologies for industrial applications such as wastewater treatment and the biofuel industry.Additionall... the book considers microbial remediation of hazardous and toxic waste, microbial fuel cells, and strategies for plastic waste degradation. Emerging technologies, such as AI integration, microbial nanotechnology, and engineered microbes are discussed, along with their environmental impacts and potential for scaling up to commercial applications.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

  • Morbidity Prevention in Aging

    The Role of Salutogenesis Amidst Crises
    • 1st Edition
    • Nestor Asiamah + 3 more
    • English
    Morbidity Prevention in Aging: The Role of Salutogenesis Amidst Crises addresses the urgent need to rethink disease prevention strategies for an aging population. The book begins by exploring how age-friendly environments support health-seeking behaviors. The next section focuses on developing personal skills such as resilience and self-efficacy for maintaining health during crises. Section III examines the reorientation of health services to support preventive care, including community care and diet promotion, while Section IV addresses the creation of policies that facilitate health-promoting interventions and integrate prevention strategies. Community engagement and empowerment in promoting health is emphasized in the fifth section.The book concludes by providing a framework for understanding disease prevention amidst crises, focusing on diverse racial, cultural, and socioeconomic experiences and ensuring equitable opportunities for lifelong disease prevention. This groundbreaking book emphasizes a salutogenic approach that focuses on factors promoting health rather than merely treating diseases. It provides a comprehensive framework for understanding how to maintain health and prevent diseases across the lifespan, even amidst challenges such as wars, climate change, and industrial hazards.

  • Cellular Senescence and Cardiac Aging

    Mechanisms, Therapeutic Strategies, and Implications for Cardiovascular Diseases
    • 1st Edition
    • Gaurav Gupta + 4 more
    • English
    Cellular Senescence and Cardiac Aging: Mechanisms, Therapeutic Strategies, and Implications for Cardiovascular Diseases offers a comprehensive and up-to-date exploration of the molecular and cellular processes driving cardiac aging, with a special focus on cellular senescence. This authoritative volume bridges cutting-edge, basic science with clinical applications, detailing how senescent cells contribute to age-related cardiovascular diseases and highlighting innovative therapeutic approaches such as senolytics and regenerative medicine. Ideal for graduate students, researchers, and clinicians in biomedical sciences, cardiology, pharmacology, and regenerative medicine, this book provides essential insights into biomarkers, epigenetics, autophagy, and emerging treatments.With contributions from global experts, it also addresses gender and ethnic disparities, ensuring a broad and inclusive perspective. This indispensable resource equips readers with the knowledge needed to advance research and improve patient care in the rapidly evolving field of cardiac aging.

  • Cyclodextrin Glucanotransferase

    A Comprehensive Guide from Gene to Applications
    • 1st Edition
    • Kiransinh Rajput
    • English
    Cyclodextrin Glucanotransferase: A Comprehensive Guide from Gene to Applications explores the essential role of cyclodextrin glucanotransferase (CGTase) in starch degradation and its diverse industrial applications. This book serves as a valuable resource for researchers and industry professionals, offering comprehensive insights from the genetic basis of CGTase to its practical applications. The book covers the production of CGTase by different bacterial genera, including Bacillus spp., and their purification strategies. It delves into the structural and functional characteristics of CGTase, highlighting its catalytic mechanisms, substrate specificity, and factors affecting enzyme activity and stability. Additionally, the book explores recombinant CGTases, their properties, and advancements in protein engineering and enzyme immobilization. With a strong focus on practical applications, the book discusses the remarkable properties of cyclodextrins, such as inclusion complex formation, and their wide range of uses in various industries, including pharmaceuticals, textiles, bioremediation, and food. Detailed case studies and real-world examples illustrate how CGTase and cyclodextrins can address specific challenges and drive innovation in these fields.This book is an essential resource for applied science researchers working in the field of starch processing enzymes, providing them with the knowledge to advance their research and development. It also serves as a valuable reference for researchers in the starch processing industries, offering insights into the latest advancements and practical applications of CGTase and cyclodextrins.

  • PACAP

    From Discovery to Function
    • 1st Edition
    • David Vaudry + 1 more
    • English
    PACAP: From Discovery to Function in Health and Disease serves as a comprehensive review covering all aspects of PACAP and its receptors, from expression to function in healthy tissues and disease models. The book introduces the biochemical, pharmacological and signaling properties of PACAP before exploring the biological actions of PACAP in normal health and pathological conditions. It considers PACAP in relation to various aspects, including pain, stress, brain injury, tumor cells and neurodegenerative disease. Effect on peripheral organs is also covered, from the gastrointestinal tract and cardiovascular system to immune cells and bones, among others. Therapeutic potential is also explored. This is a volume in the Molecular Mediators in Health and Disease book series, and provides a complete analysis of PACAP and the latest research in the field. Thus it is an ideal guide for researchers interested in PACAP and its impact across health and disease.

  • Hormones in Neuroscience

    The Pancreas and Pancreatic Hormones
    • 1st Edition
    • Victor R. Preedy + 3 more
    • English
    Hormones in Neuroscience: The Pancreas and Pancreatic Hormones explores the latest research in neuroendocrinology in relation to the pancreas and pancreatic hormones. This volume aims to cover the deficiencies in existing literature on the link between hormones and neurological tissues. This book offers translational context and seeks to address behavioral consequences of altered endocrine gland pathology, while also addressing causative and modulating influences.

  • Advances in Digital Pathology and Artificial Intelligence in Pathology

    • 1st Edition
    • Anil V. Parwani + 1 more
    • English
    Advances in Digital Pathology and Artificial Intelligence in Pathology is a comprehensive resource in digital pathology and AI technologies and applications for practicing pathologists, pathology trainees, and computational pathology scientists. This is a must-have guide to understand and potentially implement these latest technologies during routine practice and research activities. As pathology has been transformed in recent years with the large-scale integration of digital technology and AI there has been a great deal of technologic and practical advancements. This book lays the foundation of understanding these technologies as well as applying them making the book essential in both practice and research.

  • Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures

    • 1st Edition
    • Manuel Herrero Trujillano + 4 more
    • English
    Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures ameliorates the dearth of literature covering interventional pain procedures under both X-ray and ultrasound guidance. While existing resources focus on either modality separately, this book fills the gap by providing a consolidated approach, leveraging the strengths of both techniques. By doing so, it ensures practitioners have access to the most versatile and effective imaging methods available. This book is inherently practical, designed to serve as a go-to guide for clinicians facing real-world challenges in pain management. Its organization by body areas facilitates quick access to relevant techniques, while step-by-step guidance and visual aids ensure clarity and ease of understanding. By focusing on clinical relevance, the book empowers practitioners to implement evidence-based imaging interventions with confidence and precision. Hybrid Fluoroscopy and Ultrasound Guided Interventional Pain Procedures has the potential to make a meaningful impact on the field of pain management. By equipping practitioners with cutting-edge imaging techniques and insights, it promises to improve patient outcomes and advance the standard of care. Moreover, its global reach ensures that its benefits extend far beyond geographical boundaries, reaching pain medicine practitioners worldwide.

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