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Books in Life sciences

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    • Human Growth and Development

      • 3rd Edition
      • November 18, 2021
      • Noel Cameron + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 6 5 2 0
      • eBook
        9 7 8 0 3 2 3 8 5 3 6 2 0
      Human Growth and Development, Third Edition provides a comprehensive volume covering the biology of human growth and the genetic, endocrine, environmental, nutritional, and socio-economic factors that contribute towards its full expression. Human Growth and Development continues to be a valuable resource for researchers, professors and graduate students across the interdisciplinary area of human development. For the new edition, updates are made to all fourteen of the "core chapters" of the book which form the essential reading for a comprehensive understanding of human growth and development. Additionally, new special topics are covered including the interpretation of recently found sub-adult fossils that expand our understanding of the evolution of human growth and a discussion of the early pattern of growth and development as the developmental origins of risk for non-communicable diseases of adulthood. Human Growth and Development, Third Edition includes contributions from the well-known experts in the field and is the most reputable, comprehensive resource available.

    • Functional Foods and Nutraceuticals in Metabolic and Non-communicable Diseases

      • 1st Edition
      • November 30, 2021
      • Ram B. Singh
      • English
      • Paperback
        9 7 8 0 1 2 8 1 9 8 1 5 5
      • eBook
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      Functional Foods and Nutraceuticals in Metabolic and Non-communicable Diseases presents strategies for the prevention of non-communicable diseases and undernutrition through the use of functional foods and nutraceuticals. Research has shown that the use of certain functional foods and nutraceuticals, including spices, herbs, and millets, animal foods and plant foods can play a role in the treatment and prevention of various diseases and in health promotion. Finally, the book explores epigenetic modulation as a new method for the development of functional foods and functional farming. Intended for nutritionists, food scientists and those working in related health science professions, this book contributes to the discussions focused on nutritional transition, globalization, how to administer foods in the treatment of metabolic syndrome, hypertension, diabetes, heart attacks, neuropsychiatric disorders, bone and joint diseases, and carcinogenesis.

    • Therapeutic Strategies to Overcome ALK Resistance in Cancer

      • 1st Edition
      • Volume 13
      • January 5, 2021
      • Luc Friboulet
      • English
      • Hardback
        9 7 8 0 1 2 8 2 1 7 7 4 0
      • eBook
        9 7 8 0 1 2 8 2 1 7 7 9 5
      Therapeutic Strategies to Overcome ALK Resistance in Cancer, Volume 13, presents current strategies to improve and prolong clinical benefit in ALK driven cancers. Most patients with ALK-driven cancer are sensitive to tyrosine kinase inhibitor (TKI) therapy, but resistance invariably develops. This book discusses topics such as structure and function of ALK, ALK rearranged lung cancer, resistance mechanisms to ALK TKI tumors, and novel therapeutic strategies to enhance crizotinib anti-tumor efficacy in ALCL. Additionally, it encompasses information on drug combinations to enhance ALK TKI anti-tumor efficacy in neuroblastoma and future perspectives in the field. This book is a valuable resource for cancer researchers, clinicians and several members of biomedical field who need to understand more about how to fight ALK resistance in cancer treatment.

    • Clinical Pharmacology During Pregnancy

      • 2nd Edition
      • September 23, 2021
      • Donald Mattison + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 9 0 2 3
      • eBook
        9 7 8 0 1 2 8 1 8 9 0 3 0
      Clinical Pharmacology During Pregnancy, Second Edition is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals involved in the care of women during pregnancy. The book focuses on the impact of pregnancy on drug disposition and includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. This update includes substantially expanded sections on the ethics of pharmacological research in pregnancy and physiologic changes, along with new sections on patient reported outcomes in pregnancy, delivery and postnatal care, and the use of pharmacokinetic and pharmacodynamic approaches to estimate maternal, placental and fetal dosing. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are also covered, as are research issues, including clinical trial design and ethical considerations.

    • Gigantism and Acromegaly

      • 1st Edition
      • June 1, 2021
      • Constantine A. Stratakis
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 5 3 7 1
      • eBook
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      Gigantism and Acromegaly brings together pituitary experts, taking readers from bench research, to genetic analysis, clinical analysis, and new therapeutic approaches. This book serves as a reference for growth hormone over-secretion and its diagnosis and treatment for endocrinologists, pediatricians, internists, and neurosurgeons, and for geneticists. Pharmaceutical companies may use it as a reference for drug development and research. Students, residents and fellows in medicine and endocrinology and genetics will also find it valuable as it provides a single up-to-date review of the molecular biology of gigantism and acromegaly as well as recommended approaches to evaluation and management. Acromegaly is a rare pituitary disorder that slowly changes its adult victim’s appearance over time: larger hands and feet, bigger jaw, forehead, nose, and lips. Generally, a benign pituitary tumor is the cause and symptoms of acromegaly can vary from patient to patient, making a diagnosis difficult and prolonging suffering for years. Early detection is key in the management of acromegaly as the pathologic effects of increased growth hormone (GH) production are progressive and can be life-threatening as the result of associated cardiovascular, cerebrovascular, and respiratory disorders and malignancies.

    • Peripartum Cardiomyopathy

      • 1st Edition
      • January 8, 2021
      • Karen Sliwa
      • English
      • Paperback
        9 7 8 0 1 2 8 1 7 6 6 7 2
      • eBook
        9 7 8 0 1 2 8 1 7 6 6 8 9
      Peripartum Cardiomyopathy: From Pathophysiology to Management covers the pathophysiology and the heterogenous mode of presentation of PPCM to assist in risk stratification and provide a guide for the acute and long-term management of women affected by this serious condition. Each chapter provides structured figures and practical algorithms as well as prints of electrocardiograms, echocardiographic, MRI images and several case studies throughout. This title is a must have reference for those doing basic research in this area as well as all healthcare providers caring for peripartum women, including obstetricians, general physicians, cardiologists, intensivists, as well as nurses caring for heart failure patients.

    • Tumor Microenvironment Regulation of Tumor Expansion

      • 1st Edition
      • April 4, 2021
      • Domenico Ribatti
      • English
      • Paperback
        9 7 8 0 1 2 8 2 2 8 0 3 6
      • eBook
        9 7 8 0 1 2 8 2 2 8 0 4 3
      Tumor Microenvironment Regulation of Tumor Expansion is a practical guide to understand and perform research on tumor microenvironments, and to support related clinical decisions. Tumor progression is linked to an imbalance between positive and negative regulators, and mainly depends on the release of specific growth factors by inflammatory or neoplastic cells. Inflammatory infiltrate contributes to tumor progression and the metastatic process, and there are many reports of associations between tumor inflammatory infiltrate, progression, and prognosis. Understanding different contexts of organs is a key factor in improving treatment outcome, especially in new therapeutic treatments targeting components of the tumor microenvironment. This book is a valuable resource for cancer researchers, clinicians, graduate students, and scientists in many biomedical fields who are interested in the complex relationship between the tumor microenvironment and its context in specific organs.

    • TDP-43 and Neurodegeneration

      • 1st Edition
      • October 23, 2021
      • Vijay Kumar + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 0 6 6 7
      • eBook
        9 7 8 0 1 2 8 2 0 4 4 0 5
      Aggregates of the TAR DNA binding protein 43 (TDP-43), are hallmark features of the neurodegenerative diseases Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD), with overlapping clinical, genetic and pathological features. TDP-43 and Neurodegeneration: From Bench to Bedside summarizes new findings in TDP-43 pathobiology and proteinopathies. The book summarizes TDP-43’s structure, function, biology, misfolding, aggregation, pathogenesis and therapeutics. It includes autophagy-mediated therapy, role of stress granule, novel genetic, cell culture-based models, systems biology for precision medicine, development of stem cells and mechanism-based therapies that can target ALS and other related neurodegenerative diseases. This book is written for neuroscientists, neurologists, clinicians, advanced graduate students, drug discovery researchers, as well as cellular and molecular biologists involved in ALS, motor neuron disease (MND) and other neurodegenerative disorders.

    • The Microbiome in Prenatal and Neonatal Life

      • 1st Edition
      • January 13, 2021
      • Josef Neu
      • English
      • Paperback
        9 7 8 0 1 2 8 2 0 5 9 0 7
      • eBook
        9 7 8 0 1 2 8 2 0 6 0 9 6
      The Microbiome in Prenatal and Neonatal Life clarifies that the microbiome in the maternal fetal unit and immediate changes that occur as new microbes are acquired postnatally play major roles in subsequent health and disease. Rapidly developing technologies for multi-omic analyses and systems biology are shifting paradigms in both scientific knowledge and clinical care with regard to this topic. In essence, we are changing the idea that newborns emerge from sterile environments. As such, in-utero colonization may have impacts on the development of immunity and metabolism that, with epigenetic modifications, will lead to diseases in later life. In addition, the microbial profile that develops during and after birth depends on mode of delivery, type of feeding (human milk versus formula), and various other environmental factors to which the newborn is exposed.

    • Atlas of the Human Hypothalamus

      • 1st Edition
      • February 4, 2021
      • Bertalan Dudas
      • English
      • Hardback
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      • eBook
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      The Atlas of the Human Hypothalamus presents for the first time a detailed view of the cyto- and myeloarchitecture of the human hypothalamus. Providing high-resolution images of consecutive coronal sections, this book illustrates the brain area that is responsible for maintaining the homeostasis of the body by direct neuronal projections as well as by linking the central nervous system to the endocrine system. The primary goal of this atlas is to provide detailed morphological understanding of the hypothalamic structures that control numerous vital functions as well as to provide a tool to target hypothalamic areas during deep brain stimulation.

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