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Elsevier

Books in Life sciences

  • Gallin and Ognibene's Principles and Practice of Clinical Research

    • 5th Edition
    • John I. Gallin + 2 more
    • English
    Gallin and Ognibene’s Principles and Practice of Clinical Research, Fifth Edition provides the definitive text on clinical research as written by internationally recognized experts from the National Institutes of Health, the US Food and Drug Administration, academia, and global researchers. This new edition contains more than 30 new authors and 9 new chapters. Topics covered emphasize the role of informatics in clinical research, incorporating clinical outcome assessment into endpoints for decision-making, inclusion of diverse and vulnerable research subjects, patient advocacy groups, rare disease research, preparing research for pandemics, public health emergencies, research opportunities for surgeons, and content on preclinical animal studies.For the international researcher, two new chapters detail international clinical research experiences in South Africa, India, and Pakistan. As with the previous edition, the new release provides readers with summary questions and answers after each chapter.

  • Biomaterials in Cancer Therapy

    Innovations and Applications
    • 1st Edition
    • Alok Raghav
    • English
    Biomaterials in Cancer Therapy: Innovations and Applications explores the critical role of functional biomaterials in addressing one of today’s most pressing health challenges—cancer. Despite advancements in therapies, cancer continues to claim millions of lives annually, necessitating innovative approaches that integrate engineering and pharmaceutical sciences. This book highlights the potential of engineered biomaterials to enhance drug delivery, minimize side effects, and promote tissue regeneration, ultimately improving patient outcomes. The content examines cutting-edge innovations in functional biomaterials, including their applications in targeted drug delivery and immunotherapy, while emphasizing the role of nanotechnology in developing effective cancer theranostics with minimal toxicity. Targeted at academicians, physicians, and industry professionals, this book serves as a vital resource for understanding the transformative potential of functional biomaterials in oncology. By addressing real-world challenges and incorporating diverse perspectives, it inspires innovative solutions that enhance global healthcare outcomes for cancer patients.

  • Carbon Incentives, Plans, and Policies in Agriculture

    • 1st Edition
    • Ram Swaroop Meena + 3 more
    • English
    Economic incentives intended to catalyze environmentally responsible behavior have assumed a central role in confronting climate change, food insecurity, and natural resource degradation. Notwithstanding their promise, many programs underperform owing to methodological gaps, limited transparency, and insufficient regulatory oversight. Carbon Incentives, Plans, and Policies in Agriculture undertakes a critical appraisal of these constraints and advances evidence‑based propositions for strengthening carbon credit mechanisms across agricultural systems and value chains.The volume assembles a globally diverse authorship to synthesize emergent strategies and forward trajectories in carbon financing and monetization, green accounting, ecological and environmental economics, and carbon credit trading, while situating these within the broader sustainability imperatives of agroecosystems. Distinctive emphasis is placed on measurement and methodological rigor, including quantification protocols, MRV frameworks, and domain‑specific estimation approaches for soils, croplands, grasslands, and agroforestry, together with field-level interventions (e.g., energy and water use efficiency, best management practices, and green manuring) and technological enablement (notably, AI-supported assessment). Integrating scientific, policy, and economic perspectives, this book furnishes a conceptual and operational foundation for scholars, researchers, industry practitioners, and policymakers seeking to design effective, transparent, and equitable governance and planning protocols for a low‑carbon agricultural transition.

  • Advances in Research on Pediatric Gender Affirming Healthcare

    • 1st Edition
    • Danielle Moyer + 2 more
    • English
    Advances in Research on Pediatric Gender Affirming Healthcare summarizes recent and ongoing research efforts across global regions in the field of pediatric gender affirming healthcare. The book begins with an overview of the current and historical context in which research and clinical practice of pediatric gender affirming care occurs. It goes on to cover gender development and developmental pathways, risk, and resilience among transgender and gender diverse youth, and provides an overview of healthcare and barriers to access before exploring specific care models for pediatric gender affirming healthcare.The final chapter summarizes the current state of research, highlights key gaps in scientific knowledge, and asserts a call to action to researchers in the field to answer principal questions with high-quality research methods. Contributors from diverse backgrounds and experience come together with informative scientific findings in an effort to reduce bias and better meet the needs of this marginalized group of young people.

  • Clinician’s Guide to Headache

    Head, Neck, and Face Pain Syndromes
    • 1st Edition
    • Pravin Thomas
    • English
    Clinician’s Guide to Headache: Head, Neck and Face Pain Syndromes is a comprehensive reference that covers what headache specialists encounter in day-to-day headache practice settings. This practical volume is relevant as a primary reference for neurologists and other headache specialists looking for a resource on complex, acute headache management. Developments in the field are highlighted, including biologics and invasive and non-invasive neuromodulation. Chapters focus on anatomy and pathophysiology, neuroradiology, acute and chronic headaches, and clinically relevant sections on diagnosis and biases, consultation settings, placebos and nocebos, as well as the set-up of a comprehensive headache center.With a foundation based on recent developments in pathophysiology and anatomy, this volume provides an overview of headache disorders with a case-based approach.

  • Peptides in Antifungal Therapy

    Cutting-Edge Innovations and Clinical Applications
    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Peptides in Antifungal Therapy: Cutting-Edge Innovations and Clinical Applications takes an interdisciplinary and comprehensive approach to antifungal peptides and the effective ways they can be utilized to combat fungal infections and improve antifungal therapies. The book begins with an introduction to antifungal peptides. It also discusses the natural and synthetic sources of antifungal peptides, details the molecular mechanisms by which these peptides fight fungal infections, and explores the clinical applications and deliver the therapeutic potential of antifungal peptides. This book will be a very useful resource for those engaged in the study of fungal infections and peptide-based therapeutics.

  • Microplastics and Nanoplastics in Human Health

    Pathways of Exposure and Toxicological Impacts
    • 1st Edition
    • Mohammad Hadi Dehghani + 2 more
    • English
    Microplastics and Nanoplastics in Human Health: Pathways of Exposure and Toxicological Impacts is a comprehensive exploration on how microscopic plastic particles affect human health. While much attention has been paid to environmental impacts, this book focuses on the biological consequences of human exposure. It traces the journey of plastics from global production to their breakdown into micro- and nanoplastics, detailing how they enter the body through food, water, air, and skin contact. The book investigates toxicological mechanisms—such as inflammation, oxidative stress, and endocrine disruption—linking plastic exposure to chronic diseases.In addition, it examines how these particles and their chemical additives may harm key systems, including respiratory, digestive, nervous, endocrine, reproductive, and immune systems. Real-world case studies highlight exposure risks across different populations and environments. By integrating human biomonitoring data with advanced risk assessment frameworks, the book offers a scientific foundation for health professionals, researchers, and policymakers.

  • Bio-functional Cosmetics for Health

    Exploring Nature’s Ingredients for Safety, Efficacy, and Sustainability
    • 1st Edition
    • Alexandros Tsoupras + 1 more
    • English
    Bio-functional Cosmetics for Health: Exploring Nature’s Ingredients for Safety, Efficacy, and Sustainability bridges the gap between cosmetics, nutraceuticals, and pharmaceuticals, providing the latest research for developing health-promoting cosmeceuticals and nutricosmetics from various food sources and food waste. From medicinal plants, teas, cacao, coffee, fruits, vegetables, plant oils, nuts, and cereals to marine microorganisms, fungi, insects, crustaceans, and more, this book takes a close look into the safety, efficacy and sourcing of bioactives from these food sources and how they can be sustainably used as ingredients to create bio-functional cosmetics, cosmeceuticals and nutricosmetics.Reade... will gain insight on the anti-inflammatory, antioxidant, anti-aging, and anti-cancer properties of bioactive ingredients in cosmetics and will also be informed on the latest regulatory and safety issues and R&D trends for the application of bioactives in functional cosmetics and cosmeceutical products.

  • COVID-19 in New York City

    Public Health Crisis and its Aftermath
    • 1st Edition
    • Rainer W.G. Gruessner
    • English
    COVID-19 in New York City: A Five-Year Account presents a comprehensive account of the pandemic, from how events unfolded, how circumstances were handled, and how New Yorkers learned to better manage a similarly deadly pandemic in the future. The book documents the period from when the first case was diagnosed in New York City, addressing the medical, political, social, psychological, business, and environmental aspects, as well as the changes in behavior and lifestyle. The author shares his birds eye view of the city through a comprehensive investigation of the events, and the impact of the current and future implications for all readers.This book serves as a guide for anyone interested in how to handle and cope with a future deadly pandemic or similar disaster and is written by a physician and advocate for science who was living in New York City during the pandemic.

  • Advances in Hepatorenal Syndrome Research

    Untangling Pathophysiology, Improving Diagnostic Strategies, and Leveraging Therapeutic Innovations
    • 1st Edition
    • Justin Belcher
    • English
    Advances in Hepatorenal Syndrome Research: Untangling Pathophysiology, Improving Diagnostic Strategies, and Therapeutic Innovations is a comprehensive review of the historical perspectives, prevalence, and prognosis of HRS, offering insights into its evolving clinical recognition and shifting paradigms of pathophysiology. Explore the multifaceted pathophysiology of HRS as experts navigate the complexities of cardiac dysfunction, inflammatory cytokines, and other modern understandings shaping the field. Explore differential diagnosis, uncovering alternative etiologies and current diagnostic criteria, while shedding light on biomarkers and novel diagnostic tests revolutionizing patient assessment. Contents will also guide readers through the utility of point-of-care ultrasound in intravascular volume assessment sets the stage for exploring medical therapy options, including vasoconstrictors and albumin usage. Written by a team of experts, this comprehensive reference highlights the intricate pathophysiology of hepatorenal syndrome while delivering the most up-to-date insights into diagnostic and therapeutic approaches. Historically overshadowed by grim prognoses, hepatorenal syndrome has undergone a renaissance of interest due to recent breakthroughs, revolutionizing treatment paradigms. Whether you're a seasoned practitioner or a burgeoning researcher immersing yourself in this dynamic field, this resource offers a thorough examination, encompassing novel diagnostic criteria, innovative biomarkers, and state-of-the-art treatments.

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