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Elsevier

Books in Life sciences

  • AI Technologies for Crop Breeding

    • 1st Edition
    • Jen-Tsung Chen
    • English
    AI Technologies for Crop Breeding offers the latest insights into the use of artificial intelligence models to improve plant health and production. Presenting applications of AI technologies in plant biology, biotechnology, and crop breeding, it explores practices for the mitigation of biotic and abiotic stressors as well as other plant growth challenges.AI-based technologies are expected to advance approaches to plant functional genomics and multiple omics, resulting in smarter and more efficient crop breeding for next-generation agriculture helping to address the challenges of the increasing human population and the globally changing climate. AI tools such as machine learning, particularly deep learning, have been applied to predict chief players in complicated biological networks, increasing the understanding of in-depth mechanisms of plant-pathogen and plant-environment interactions. Additionally, responses of plants facing stress can be modeled using AI technologies, and the resulting data are valuable not only to plant stress physiology but also for stress-resilient and disease-resistant crop breeding.This book introduces AI technologies for studying plant biology, focusing on machine learning and deep learning models for integrating multiple omics approaches and revealing the knowledge of plant functional genomes. Technological advancements and emerging applications of machine learning and deep learning in genomic selection, genome-wide association study (GWAS), phenotyping and constructing phenomics, and transcriptomics are also featured in this book.AI Technologies for Crop Breeding is an ideal reference for researchers, academics, and advanced-level students and professors in the fields of plant sciences, plant stress physiology, bioinformatics, systems biology, and crop breeding.

  • Ketamine

    Fundamentals, Applications, Pharmacology, and Clinical Aspects
    • 1st Edition
    • Albert Dahan + 1 more
    • English
    Pharmacology of Ketamine: Fundamentals, Applications, Delivery Systems and Clinical Aspects explores the multifaceted properties of ketamine for diverse applications, delving into dosing strategies, routes of administration, and their pharmacological implications. The book begins with an introduction that underscores the need to bridge research and practice. It then delves into the pharmacological intricacies of ketamine, dissecting mechanisms and dosing strategies and exploring the diverse routes of administration and their impact on ketamine's metabolites.The book then explores the PK and PD characteristics of ketamine, followed by a deep dive into clinical applications emphasizing anesthesia, psychiatric therapy, and emerging treatments. The final part of the book covers addiction, toxicity, and future research perspectives. It will serve as a comprehensive reference tailored to the needs of both researchers and clinicians involved in the administration and study of ketamine.

  • Artificial Metalloproteins

    • 1st Edition
    • Volume 720
    • English
    Artificial Metalloproteins covers artificial metalloproteins (ArMs) and how they have emerged as powerful vehicles with which to control, implement, and leverage the unique reactivity and spectroscopic properties of their bound metal ions. Chapters in this release include Incorporating Non-Native Cofactors into Heme Proteins, Designing 4-Helix Bundles to Bind Porphyrin/Porphyrin-... Cofactors, Cobalt-Substituted Hemoprotein Expression, Rationally designed directed evolution of cytochrome P450 enzymes, De novo design of a switchable a-helical hemoprotein, Primary Coordination Sphere Part B: Unnatural Metal-Binding Sites Beyond the Heme, and more.Other sections cover Unnatural Amino Acid Incorporation for Creating Artificial Metalloenzymes, Development of a PQQ-Dependent Artificial Metalloprotein, Evolutionary Engineering of a Rhodium Complex-Linked Artificial Metalloenzyme, Design and Application of Nonheme Iron Enzymes, Part C: Secondary Sphere Modulation for Metallocofactor Activation, Designing Artificial Metalloenzymes by Engineering the Primary and Secondary Coordination Sphere in Native Protein Scaffolds, and much more.

  • Data-Driven Diagnostics and Disease Prediction with AI Optimization

    • 1st Edition
    • Shailendra Pratap Singh + 3 more
    • English
    Data-Driven Diagnostics and Disease Prediction with AI Optimization provides useful insights into model creation, data preparation, and ethical issues for healthcare applications. The book covers all the conventional and non-conventional methods related to this domain. It also discusses AI-based optimization techniques, Machine Learning models, and Advanced AI, offering practical insights, case studies, and optimization strategies to help data scientists and researchers efficiently employ AI in diagnostics and illness prediction in a world where precise diagnostics and early illness prediction may save lives and healthcare resources.

  • Advanced Cancer Research Protocols

    • 1st Edition
    • Volume 198
    • English
    Advanced Cancer Research Protocols, Volume 198 is a comprehensive and cutting-edge resource dedicated to the latest methodologies and protocols in the field of cancer research. Topics in this new release include Introduction to Cancer Biology and Current Research Trends, Cell Culture Techniques for Cancer Research, Practical Approaches to Advanced Molecular Biology Techniques, High-throughput sequencing Technologies for Cancer Genomics, Epigenetic Analysis in Cancer Research, Proteomics and Metabolomics in Cancer Biomarker Discovery, In vivo Cancer Modeling Using Mouse Models, and much more.Other sections highlight advances in Advanced Imaging Techniques for Cancer Research, Cancer Stem Cell Analysis and Targeting, Immunotherapy and Cancer Vaccine Development, Gene Editing Techniques in Cancer Research, Single-Cell Analysis in Cancer Research, Liquid Biopsy and Circulating Tumor Cell Analysis, and Exploring the Tumor Microenvironment in Solid Cancer: From Biology to Therapy.

  • Fungal and Protozoan Carbonic Anhydrases

    • 1st Edition
    • Volume 57
    • English
    Fungal and Protozoan Carbonic Anhydrases, Volume 57 in The Enzymes series, explores recent advancements in the study of fungal and protozoan carbonic anhydrases (CAs). This volume presents a comprehensive collection of chapters covering various aspects of these enzymes, including an overview of fungal and protozoan CAs (genetics, molecular biology, and phylogenetics), the structure and function of fungal α-carbonic anhydrases, and an in-depth look at β-carbonic anhydrases in Saccharomyces cerevisiae, Candida spp., and Cryptococcus neoformans.Additiona... chapters delve into the Malassezia spp. and Sordaria macrospora CAs, as well as protozoan CAs from Plasmodium falciparum, Trypanosoma cruzi, Leishmania spp., Toxoplasma gondii, and Entamoeba histolytica. The volume also addresses the challenges in developing selective fungal and protozoal CA inhibitors as anti-infective agents, providing insights into their potential biomedical applications.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 129
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Temperate Tree Fruits and Nuts

    • 1st Edition
    • George Manganaris
    • English
    Temperate Tree Fruits and Nuts serves as a comprehensive resource, providing up-to-date knowledge about economically significant temperate fruit crops. This textbook covers the history, genetic improvements, and growth physiology of these crops. It details orchard establishment, management practices, and harvest considerations, making it a standalone guide to sustainable fruit crop production in temperate climates. Targeted toward undergraduate and postgraduate students, as well as professionals in pomology, horticulture, and related fields, the book is essential for researchers, farmers, consultants, and agribusiness professionals.Each chapter, authored by an expert, provides an introduction, botany, orchard management, propagation, rootstocks, cultivars, and disease and pest management. It also covers ripening, harvest criteria, postharvest physiology, and technology, complemented by high-quality illustrations and a question bank for instructors.

  • Quantitative Human Physiology

    An Introduction
    • 3rd Edition
    • Joseph J Feher
    • English
    Quantitative Human Physiology: An Introduction, Third Edition, winner of a 2018 Textbook Excellence Award (Texty), is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time but requires a more analytical/quantitat... approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles, with an emphasis on quantitative aspects. The third edition has been revised with more and expanded problem sets and improved illustrations.

  • Functional RNAs in Plants

    Developing Climate-Resilient and Stress-Resistant Crops
    • 1st Edition
    • Jen-Tsung Chen
    • English
    Functional RNAs in Plants explores the rapidly advancing field of plant RNA biology and its transformative role in modern agriculture. Covering microRNAs, small interfering RNAs, long noncoding RNAs, circular RNAs, and CRISPR-associated RNAs, the book explains their identification, design, structural and functional analysis, and applications in crop improvement.Chapters address both abiotic and biotic stresses, highlighting how functional RNAs regulate tolerance to climate-driven challenges as well as plant–microbe interactions and disease resistance. Technical sections detail progress in bioinformatics, integrated multi-omics, spatial and single-cell approaches, and high-throughput transcriptomics, which together provide new insights into RNA networks underlying plant stress responses. The book also discusses artificial small RNAs, secondary metabolism, and competing endogenous RNA systems, connecting mechanistic understanding with applied breeding strategies.Practical guidance is offered on integrating RNA knowledge into smart breeding, sustainable agriculture, and CRISPR-based innovations, with emphasis on designing and delivering functional guide RNAs for crop improvement. By combining foundational concepts with emerging applications, this volume serves as a valuable reference for academics, researchers, and advanced-level students in plant molecular biology and agricultural biotechnology.

  • Enzymatic Production of Oligosaccharides

    From Basic Research to Industrial Production
    • 1st Edition
    • Carlos Vera + 2 more
    • English
    Enzymatic Production of Oligosaccharides: From Basic Research to Industrial Production, a volume in the Foundations and Frontiers of Enzymology series, covers the enzymes used for the extraction, synthesis, or modification of oligosaccharides, the biochemical properties of those enzymes, and potential technological applications. The book is divided into three parts, the first of which shares the fundamentals on the enzymatic synthesis of oligosaccharides. The book then explores the enzymatic production of oligosaccharides, considering a range of different oligosaccharides and production processes. Final sections cover the technological properties of oligosaccharides and potential applications across the chemical, biochemical, biotechnology, and food industries.This is a useful reference for researchers working with oligosaccharides across biochemistry, enzymology, biotechnology, food chemistry and related fields.

  • Advances in Virus Research

    • 1st Edition
    • Volume 123
    • English
    Advances in Virus Research, Volume 123 in this esteemed series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Sections in this new release include Transcriptional Regulation of Human Endogenous Retroviruses in Cancer, Nomenclature for vertically transmitted plant, Modelling of vertically transmitted viruses, Vertical transmission of tomato viruses, and more.

  • Strategies to Modify the Drug Release from Pharmaceutical Systems

    • 2nd Edition
    • Marcos Luciano Bruschi
    • English
    Strategies to Modify the Drug Release from Pharmaceutical Systems, Second Edition serves as a vital reference on contemporary models aimed at achieving the precise therapeutic dosage and timing of drug release. The book provides updated strategies, mathematical models, routes of administration, and technologies, all presented succinctly and objectively. This six-chapter guide covers general concepts of drug release modification and classification of therapeutic systems, including passive versus active targeting. It delves into mechanisms to control drug release, discussing materials and technologies, and introduces mathematical and physicochemical models of drug release.Furthermore, it reviews drug delivery systems like 3D printing, nose-to-brain delivery, environmentally responsive systems, and new lipid systems, making it indispensable for pharmaceutical scientists, graduate students, materials scientists, and chemists.

  • Bioprospecting of Natural Pigments in Human Health

    • 1st Edition
    • Siva Ramamoorthy + 1 more
    • English
    Bioprospecting of Natural Pigments in Human Health provides a comprehensive overview of the therapeutic potential of these compounds. Covering the main pigment classes sourced from plants, algae, and microbes, the book is organized around the applications to specific diseases and conditions. With chapters on the anti-cancer, antidiabetic, anti-microbial, anti-inflammatory, anti-aging effects, cardioprotective and neuroprotective agents, the book covers the molecular biology principles of action, as well as bioavailability and structure. This is the ideal reference for academic researchers interested in natural products pharmacology. It is also beneficial for the academic and corporate researchers in food sciences and the nutraceutical industries.

  • Artificial Intelligence in e-Health Framework, Volume 2

    Telemedicine Applications, Drug Delivery, Augmented Reality, and Robotics
    • 1st Edition
    • Sudip Paul + 1 more
    • English
    Artificial Intelligence in e-health Framework, Volume Two: Telemedicine Applications, Drug Delivery, Augmented Reality, and Robotics offers a comprehensive exploration of AI’s role in enhancing medical solutions. Through a focus on machine learning, deep learning, and their practical applications, this book aims to bridge the gap between theoretical advancements and real-world healthcare implementations. In addition to telemedicine advancements, the book explores AI-driven drug discovery, virtual and augmented reality innovations, robotics in medicine, and radiotherapy applications. It serves as an indispensable resource for professionals, researchers, and students eager to deepen their understanding of AI's contributions to modern healthcare.

  • Cancer Theranostics, Second Edition

    • 2nd Edition
    • Xiaoyuan Chen + 2 more
    • English
    Cancer Theranostics, Second Edition provide updates on new molecular imaging probes and techniques for early detection of cancer and describes molecular imaging-guided cancer therapy. Discussions also include nanoplatforms, incorporating both cancer imaging and therapeutic components, as well as clinical translation and future perspectives. New to this edition is the inclusion of recent developments and a streamlined structure that leads the reader through the content more intuitively, from problem to solution. More illustrations of different forms of cancer theranostics​ are included, and this edition also contains completely new content on DNA and RNA theranostics. In addition, new case studies are featured.This new edition is published in time to meet the needs of medical researchers in a comprehensive manner, encompassing diagnostics, in vivo imaging and its use for image-guided therapy, and a variety of other miscellaneous subjects. This book is a must-have for all research scientists, medical physicists, and physician scientists in cancer experimental therapeutics and molecular imaging.

  • ​​Environmental Greenness and Cardiovascular Health​

    • 1st Edition
    • William W. Aitken
    • English
    Environmental Greenness and Cardiovascular Health provides a comprehensive understanding of how environmental factors, particularly green spaces, impact cardiovascular health. The book bridges environmental science and medical research, offering insights into how greenness contributes to the prevention and management of cardiovascular diseases.Environment... Greenness and Cardiovascular Health begins with an introduction to cardiovascular disease and environmental factors, followed by discussions on defining and measuring greenness, historical perspectives, and the physiological and psychological benefits of green spaces. It also covers urban planning, disparities in access to green spaces, longitudinal studies, future research directions, and policy implications. Environmental Greenness and Cardiovascular Health benefits researchers, medical practitioners, urban planners, and policymakers by providing the latest methodologies, practical examples, and policy recommendations. It serves as an essential resource for understanding the intersection of environment and health, promoting informed strategies for improving cardiovascular health through environmental interventions.

  • Edible Oil Blends

    Chemistry, Functionality, and Health Aspects
    • 1st Edition
    • Mohamed Fawzy Ramadan
    • English
    Edible Oil Blends: Chemistry, Functionality and Health Aspects, gives readers insight into the advantages of blending traditional and non-traditional oils for optimal nutrition and enhanced product development. The book sheds light on how the intricate concoctions of triacylglycerol, phospholipids, carotenoids, antioxidants and fatty acids can improve nutrition and contemporary food applications.Edible Oil Blends: Chemistry, Functionality and Health Aspects, demonstrates how blended oils stemming from olive, coconut, sunflower, soybean, sesame, grapeseed and more, can alter an oil's' chemical composition for increased cooking stability, enhanced sensory characteristics and more desirable ratios of saturated, mono-and poly-unsaturated and essential fatty acids. Each chapter highlights a specific oil and discusses the bioactive compounds, physiochemical properties, biological properties and the economic value of each.

  • Kratom

    History, Science and Therapeutic Potential
    • 1st Edition
    • Jack E. Henningfield + 2 more
    • English
    Kratom: History, Science and Therapeutic Potential is the first book to address the unregulated, widespread availability of kratom, with its weak opioid and stimulant effects, coupled with limited awareness of it by healthcare professionals. Kratom has great therapeutic utility and medicinal potential, but more study, caution, and possible regulation is needed. It discusses geographical sourcing, historical uses, current worldwide uses, and potential for treatment of other medical conditions. Most exciting for healthcare professionals will be the implications of this substance's potential for treatment of diseases like depression, ADHD, PTSD, and substance-use disorder, particularly opioid use disorder (OUD).Moreover, kratom and its active alkaloid mitragynine are getting remarkable attention at federal and local governments as more than eight million Americans consume this product annually. Yet, the paucity of information for researchers and clinicians is troublesome.

  • Ovarian Cancer

    Disease, Diagnosis, and Treatment
    • 1st Edition
    • Bhupendra G. Prajapati + 2 more
    • English
    By providing a comprehensive overview of current research findings, emerging therapies, and clinical practices, Ovarian Cancer: Disease, Diagnosis and Treatment is an invaluable resource. It will not only enhance the understanding of ovarian cancer's complex biology among professionals but also guide them in applying this knowledge to improve patient outcomes The book delivers the key knowledge and information needs faced by the audience center around understanding the latest advances in the underlying pathogenesis and treatment of ovarian cancer. This encompasses a broad spectrum of requirements, from grasping the molecular and genetic factors driving ovarian cancer development to staying updated on the latest therapeutic strategies, including targeted therapies and immunotherapies. In 19 chapters Ovarian Cancer: Disease, Diagnosis and Treatment gives a timely and comprehensive coverage of advances in ovarian cancer therapy, particularly highlighting the development and utilization of Nanotheranostics technologies. This focus not only addresses a crucial and cutting-edge area of cancer treatment but also positions the book as a forward- thinking resource that delves into the potential of Nanotheranostics to revolutionize cancer diagnostics and therapy.Ovarian Cancer: Disease, Diagnosis and Treatment targets a specialized audience within the medical and scientific community, focusing on obstetricians and gynecologists, oncologists, cancer researchers, and importantly, patients with ovarian cancer. This audience selection underscores the project's dual aim of advancing scientific knowledge and directly benefiting patient care in the realm of ovarian cancer, bridging the gap between research, clinical application, and patient advocacy.

  • Role of Gut Microbiome in Neurodegenerative Disorders

    • 1st Edition
    • Mukesh Kumar Yadav + 1 more
    • English
    Role of Gut Microbiome in Neurodegenerative Disorders provides an overview of the gut microbiota and its interactions with the gut and the central nervous system. This book reviews the relevance of this axis to the pathogenesis of neurodegenerative diseases, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and Multiple sclerosis (MS). Various chapters discuss the effects of gut derived particles in various parts of brain and the targeting pathways leading to protein deposition in brain.

  • Next-Generation Cereal-Based Foods and Beverages: Breakthroughs in Technology, Sustainability, and Health

    • 1st Edition
    • Volume 117
    • English
    Next-Generation Cereal-Based Foods and Beverages: Breakthroughs in Technology, Sustainability, and Health, Volume 117 offers an in-depth examination of the latest advancements in cereal science, processing techniques, and health-oriented applications. This volume gathers insights from global experts, focusing on functional ingredient development, foodomics, and novel analytical methods aimed at improving nutritional quality, safety, and sensory features of cereal-based products. The book delves into breakthroughs in extrusion, fermentation, and milling technologies, emphasizing the significance of non-starch carbohydrates, bioactive compounds, and plant-based protein alternatives in driving sustainable food systems.It also covers consumer behavior, regulatory issues, and industry challenges, making it an essential resource for scientists, food industry professionals, and policymakers committed to creating the next generation of health-enhancing and environmentally friendly cereal foods and beverages.

  • The Scientific Basis of Fatigue

    • 1st Edition
    • Colin R. Martin + 3 more
    • English
    Fatigue is a prevalent problem and adequate treatment is challenging because many conditions, disorders, medications, and lifestyle factors can cause fatigue. The Scientific Basis of Fatigue combines evidence-based research and clinical treatment protocols to provide a comprehensive reference to fatigue. This book is divided into seven distinct sections, starting with an introduction section defining the distinctions between physical and mental fatigue. The second and third sections detail the various conditions in both physical and mental fatigue including COVID, Parkinson disease, and depression. The next section reviews the current research on molecular and cellular aspects and models of fatigue. The final two sections review options for diagnosis and treatments for fatigue and provides a detailed resource section for further review.

  • Seafood 4.0

    Digital, Physical, and Biological Innovations from Sea to Table
    • 1st Edition
    • Abdo Hassoun + 1 more
    • English
    Seafood 4.0: Digital, Physical, and Biological Innovations From Sea to Table serves as a comprehensivesource of information about the fourth industrial revolution (Industry 4.0) innovations and relevanttechnologies used in fisheries, aquaculture, and the seafood industry. The book is divided into fivesections, each exploring recent groundbreaking innovations and technological advances that enhanceseafood quality, safety, and traceability. These advancements hold strong potential to reduce seafoodwaste and production costs while simultaneously improving marine sustainability, enabling effectivemanagement of this valuable food resource across the entire seafood value chain from sea to table.The chapters address the current challenges and future research directions needed to accelerate theadoption of Industry 4.0 technologies in the seafood sector. Additionally, the book sets the stage forthe next wave of innovation, paving the way for the future revolution of Seafood 5.0.Promoting multidisciplinary collaboration and accelerating the adoption of Industry 4.0 technologies,this book highlights how these innovations can lead to smart production, processing, supply chainmanagement, and consumer engagement, making it a valuable resource for anyone involved in theseafood supply chain, from production to consumption.

  • Sparkling Beverages

    Champagne and Beyond
    • 1st Edition
    • Gérard Liger-Belair
    • English
    Sparkling Beverages: Champagne and Beyond offers a complete overview of the physicochemical processes at work in a sparkling beverage. In order to achieve effervescence in a glass of champagne, precise knowledge fluid dynamics and CO2 solubility are necessary. This reference covers these concepts, as well as historical contexts and modern-day production methods of simple sparkling waters and sugar-free sparkling soft drinks to more complex alcoholic beverages, such as beers or sparkling wines. The book breaks down the science behind the fizz in our drinks while also examining sensory experiences associated with opening, smelling, and testing sparkling beverages.Written by a true expert on the topic and complete with beautiful, original photography, this unique, interdisciplinary work will interest researchers and industry producers alike.

  • Encyclopedia of Evolutionary Biology

    • 2nd Edition
    • Claudia Augusta De Moraes Russo + 1 more
    • English
    Encyclopedia of Evolutionary Biology, Second Edition, Four Volume Set is a comprehensive resource containing approximately 215 chapters that covers all fundamental topics in evolutionary biology. Featuring a consistent chapter structure, this encyclopedia ensures easy navigation across the volumes. Each chapter effectively links concepts to specific systems and examples, making it an invaluable tool for anyone interested in applying evolutionary thinking to their field of study. This edition includes new or expanded topics such as human evolution, including cultural evolution and language, paleontology, the origins of life, mass extinction events, epigenetics, and metagenomics.The encyclopedia also delves into the evolution of behavior, game theory, kin selection, optimality, human microbiomes, and the diversification of viruses. With its broad coverage, this essential resource will engage readers across various educational levels, emphasizing the central role of evolutionary biology in the life sciences. It caters to a wide range of readers, from students to experienced professionals, by offering both introductory chapters and in-depth analyses.

  • Protein Termini Part B

    • 1st Edition
    • Volume 719
    • English
    Protein termini represent a major route to protein regulation. From the moment the very first amino acid of a polypeptide chain exits the ribosome there is potential for steering from the cellular environment. This volume of <i>Methods in Enzymology Modifications and Targeting of Protein Termini</i> focuses on Protein N-termini and C-termini and their modifications which include acetylation, arginylation, myristoylation and oxidation. Also, the impact of terminal modifications is covered, in particular the impact on protein turnover and the ubiquitin E3 ligases which specifically recognize protein N-termini (N-degrons) and C-termini (C-degrons). In addition to the detailed methods and laboratory protocols, the chapters include informative overviews and reviews of the different subfields.

  • Mitochondrial Signaling and Regulation

    Immune Responses and Diseases
    • 1st Edition
    • Seyyed Shamsadin Athari + 1 more
    • English
    Mitochondrial Signaling and Regulation: Immune Responses and Diseases delves into the latest research on molecular pathophysiology mechanisms and cell signaling pathways in the pathogenesis of diseases via mitochondrial regulation. This comprehensive study underscores the importance of mitochondria in cellular processes and their role in disease development. Early chapters discuss the crucial role, regulation, and crosstalk of mitochondria, highlighting their significance in maintaining cellular health. The exploration of mitochondria mutations and mitochondria-related diseases follows, providing a detailed understanding of the genetic aspects involved.Final chapters focus on mitochondria's involvement in immune responses and allegro-inflammation... presenting the intricate connections between mitochondrial function and the immune system. The book also explores the use of biotechnology in developing new treatments and targeted therapies against mitochondrial dysfunction. This resource sets the foundation for new classifications, prevention methods, therapies, and treatments of mitochondria-related diseases, making it invaluable for scientists and researchers dedicated to this field.

  • New Opioid Receptor Modulators and Agonists

    Relevance for Pain and Opioid Use Disorder Management
    • 1st Edition
    • Alan David Kaye + 1 more
    • English
    New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.

  • Food and Agro-Industrial Wastes

    Sustainable Impacts, Transformation and Added Value of By-products
    • 1st Edition
    • Mika Sillanpää + 2 more
    • English
    Food and Agro-Industrial Wastes: Sustainable Impacts, Transformation and Added Value of By-Products offers an in-depth look at the potential of recycling food and agro-industrial waste into valuable products. This book presents the concept of sustainable development through responsible consumption and production, and introduces practical methods to transform waste into new, value-added products. It delves into various industries, such as meat, dairy, and crop processing, highlighting the ways in which residues like leaves, stems, and husks can be repurposed. Moreover, the book explores the valorization and safety of fruit and vegetable waste, including peels and skins, to enhance food products.Real-life case studies showcase how bioactive compounds, nutraceuticals, and other bio-based enzymes can be derived from waste, providing insights into innovative food product development. This comprehensive guide is an essential resource for anyone interested in sustainable waste management and the creation of functional, eco-friendly products. Globally, it is estimated 1.3 billion tons of food, valued at $1 trillion is wasted a year, according to the United Nations and the Food and Agriculture Organization. (FAO) In addition, billions of tons of agro-industrial waste from agriculture and food processing activities are generated yearly, putting a strain on natural resources, and negatively effecting the environment.

  • Innovation in Cell Death Research

    • 1st Edition
    • Volume 217
    • English
    Innovation in Cell Death Research, Volume 217 covers topics relating to the identification of unique signaling pathways, the discovery of biomarkers and innovative treatment strategies, neurodegenerative diseases, and immune-related disorders. Chapters in this new release include Cell Death Triad: Integrating Apoptotic, Autophagic, and Necrotic Cell Death Mechanisms, Advances in Cell Death Detection and Imaging, Informatic and data science for the cell death researches, Visualizing and Mapping Cell Death: Biochemical Tools, Techniques and Assays, and the Role of Autophagy in Cell Death and Survival: Mechanisms and Therapeutic Implications.Other sections cover the Role and Relation of Cell Death in Cancer Disease, Exploring Pyroptosis: From molecular mechanisms to cancer therapeutics, Current findings and potential applications of cell death research in ovarian cancer, PHAGEPTOSIS: A BACTERIAL CELL DEATH PROGRAM INDUCED BY CRISPR-CAS SYSTEMS, Cell death mechanisms in Drosophila: Responses to infectious challenges, and much more.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 132
    • English
    Advances in Applied Microbiology, Volume 132 presents a comprehensive exploration of the latest innovations in applied microbiology. The book delves into the diverse applications of microbiology across various industries, including agriculture, food production, biotechnology, environmental science, and healthcare. Through a collection of insightful chapters authored by experts in the field, readers are offered in-depth analyses of cutting-edge research, emerging trends, and practical applications of microbiological principles. From novel microbial technologies to the impact of microbiomes on human health and beyond, this book serves as a valuable resource for researchers, professionals, and students seeking to stay informed and inspired by the exciting advancements.

  • Feedback Control and Adaptive Learning in Optical-Tweezer Robotics

    • 1st Edition
    • Xiang Li + 2 more
    • English
    Feedback Control and Adaptive Learning in Optical-Tweezer Robotics is a comprehensive guide to merging robotic feedback control with optical trapping techniques in cell manipulation. It begins by providing foundational knowledge in dynamic modeling and control theory, essential for understanding optical-tweezer robotics' complexities. The book explores optical trapping principles, discussing traditional approaches' constraints and challenges. It then introduces a unified control methodology designed for dynamic adaptation to cell movement and escape scenarios, highlighting the importance of closed-loop control strategies in navigating the interaction between optical forces and robotic manipulation.Additio... the book delves into adaptive learning algorithms for real-time adjustments in unknown trapping stiffness, addressing challenges like limited field of view, stochastic disturbances, and handling multiple cells. It integrates open-access simulations and real-world experiments to reinforce theoretical concepts, offering practical examples. This unified approach's potential impact on biomedicine, biotechnology, and microscale robotics is emphasized, making it an invaluable resource for readers in these fields.

  • Robotics and Artificial Intelligence for Reproductive Medicine

    • 1st Edition
    • Guanqiao Shan + 3 more
    • English
    Robotics and Artificial Intelligence for Reproductive Medicine provides fundamental principles underpinning robotic and AI techniques used for reproductive medicine. The book provides the state-of-the-art technical advances in clinical infertility treatment, along with the outlook on future challenges and opportunities of robotics and AI in reproductive medicine. It covers robotics, AI, computer vision, biomedical engineering, and reproductive medicine.

  • Deep Learning in Drug Design

    Methods and Applications
    • 1st Edition
    • Qifeng Bai + 2 more
    • English
    Deep Learning in Drug Design: Methods and Applications summarizes the most recent methods, and technological advances of deep learning for drug design, which mainly consists of molecular representations, the architectures of deep learning, geometric deep learning, large models, etc., as well as deep learning applications in various aspects of drug design. This book offers a comprehensive academic overview of deep learning in drug design. It begins with molecular representations, CNNs, GNNs, Transformers, generative models, explainable AI, large models, etc. Next, it covers deep learning applications like protein structure prediction, molecular interactions, ADMET prediction, antibody design, and so on. Finally, a separate chapter is dedicated to the introduction of the ethics and regulation of artificial intelligence in drug design. This book is ideal for readers aiming to learn and implement deep learning methods and applications in drug design and related fields.Deep Learning in Drug Design: Methods and Applications is particularly helpful to undergraduate, graduate, and doctoral students in need of a practical guide to the principles of the discipline. Established researchers in the area will benefit from the detailed case studies and algorithms presented.

  • Development of Sensory Organs

    • 1st Edition
    • Volume 165
    • English
    Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Artificial Intelligence in Food Science

    Transforming Food and Bioprocess Development
    • 1st Edition
    • Tanmay Sarkar + 1 more
    • English
    Artificial Intelligence in Food Science: Transforming Food and Bioprocess Development covers the AI and machine learning techniques that are reshaping the food science landscape, introducing innovative solutions to improve food processing, safety, and sustainability. This book delves into the transformative potential of these cutting-edge technologies, exploring how they optimize food production, enhance bioprocess development, and tailor products to meet specific consumer needs. By integrating AI, researchers and industry professionals can address challenges such as resource efficiency and quality assurance, paving the way for a more sustainable and technologically advanced food system.Beyond optimization, the book examines AI applications in predicting food trends, analyzing complex datasets, and developing personalized nutrition plans. It provides insights into how AI enhances food storage, packaging design, and even consumer engagement through predictive models. With detailed case studies and forward-thinking perspectives, this book serves as a comprehensive guide for harnessing AI's power to revolutionize food science and bioprocess innovations.

  • The Times They are A-Changin´: On Cannabinoids and Psychedelics´ Therapeutic Potential and Social Impact

    • 1st Edition
    • Volume 296
    • English
    Cannabinoids and Psychedelics: A Therapeutic Revolution, Volume 296 offers original research, reviews, and essays, including basic science and clinical studies on cannabinoids and psychedelics. This includes basic works on the neurotransmitter systems, the effects of drugs on animal and human perception, and emotion and cognition. Chapters in this new release include Chemical diversity, receptor binding affinity and pharmacology of phytocannabinoids: insights into neuronal mechanisms, Does cannabis work for insomnia?, Testing NPSs as harm reduction strategies, Cannabis-based products in Brazil: regulation for quality improvement, Anti-prohibitionist social movement in Brazil and the strength of the Marijuana Marches, and much more.Other chapters include discussions on Philopsychedelia: The Reflorescence of Psychedelic Philosophy, Psychedelics in Palliative Care: Transcending Death and Alleviating Spiritual Suffering, High dreams: inhaled DMT increase lucid dreams and nightmares, Malaise in the psychedelic revolution: when and for whom this movement brings opportunities, and the Neurophenomenology of psychedelic-induced mystical experiences.

  • Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma

    • 1st Edition
    • Rajeev Sharma + 4 more
    • English
    Emerging Paradigms in Delivery of Therapeutic Agents for the Treatment of Glioblastoma describes the intense research and clinical developments that are required to optimize the available treatment options and the potential side effects to heal brain cancer. The success of this strategy includes the use of validated biomarkers, appropriate patient selection criteria, strategies to prevent adverse events, and the implementation of immunotherapy in multimodal treatment approach. In 18 chapters, this title sets forth the rationales for promising therapies like immunotherapy, including immune checkpoint blockade, chimeric antigen receptor T (CAR T) cell therapy, oncolytic virotherapy, and vaccine therapy.In addition, the book reviews potential novel agents, the current status of preclinical and clinical trials, and the challenges and future perspectives in glioblastoma immuno-oncology. This book is a valuable resource for health professionals, scientists and researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.

  • Sports Physician Handbook

    • 4th Edition
    • Yannis P. Pitsiladis + 3 more
    • English
    Sports Physician Handbook, the fourth edition of the Team Physician Manual: International Federation of Sports Medicine (FIMS), covers all key areas of activity and intervention, from the preparticipation examination to rehabilitation, drug testing, care of the young athlete, the female athlete, and environmental issues. The book also surveys major classifications of sports injuries, offering clear advice on field side assessment, diagnosis, and treatment. It further examines best practices in broader aspects of sports medicine, such as injury prevention and the psychology of recovery. Sports Physician Handbook continues the tradition of high-caliber authorship, featuring contributions from world-leading physicians and scientists. In short, the fourth edition represents a "must-have" reference for any doctor, scientist, physical therapist, or medical professional working in sport.

  • Aging in Ophthalmology

    • 1st Edition
    • Jorge L Alio MD + 2 more
    • English
    Aging in Ophthalmology examines the aging process of the eye and how this affects the future of ophthalmology. With a strong focus on therapeutic options, the book shows the latest improvements in medical and surgical possibilities. It describes both the risks of the aging of the eye, the aging of different parts of the eye (like the retina, lens, and iris), therapeutic approaches to limit the aging processes of the eye, along with a glance into the future. This book is a valuable resource for ophthalmologists of all subspecialties and researchers interested in the aging process in the human eye.

  • CRISPR Technology for Combating Plant Pests and Pathogens

    • 1st Edition
    • Jen-Tsung Chen
    • English
    CRISPR Technology for Combating Plant Pests and Pathogens improves the understanding of CRISPR-mediated crop protection, presenting innovative strategies for developing disease-resistant crops that can withstand a variety of biotic stresses.In agricultural food production, a range of stressors continues to challenge crop production globally. Fortunately, modern crop breeding approaches have developed rapidly, including the promising technology of plant genome editing. Leading to improvements in disease resilience or stress-tolerant crops, CRISPR/Cas9 is among the mainstream genome editing technologies for plant breeding precision and efficiency.CRISPR Technology for Combating Plant Pests and Pathogens offers in-depth summaries curated by leading experts and professors in the field of agricultural biotechnology, providing the essential knowledge needed to advance research and applications in crop resilience.

  • Sustainable Plant Foods

    A Scientific Approach to Alternative Food Sources
    • 1st Edition
    • Sajad Ahmad Wani + 2 more
    • English
    Sustainable Plant Foods: A Scientific Approach to Alternative Food Sources delves into plant-based nutrition and its transformative potential for human health and the environment. By addressing the detrimental effects of animal agriculture on well-being and ecological balance, the book advocates for a shift towards plant-based alternatives. It emphasizes the importance of sustainable diets for improving human health and nutrition while contributing to a more sustainable planet. The book explores new developments and challenges in plant-based alternatives. It covers the nutritional benefits, sensory appeal of underutilized fruits, vegetables, legumes, and strategies for developing clean-label alternatives to eggs, meat, cheese, and milk.

  • Soil Pollution

    From Monitoring to Remediation
    • 2nd Edition
    • Teresa Rocha-Santos + 2 more
    • English
    Soil Pollution: From Monitoring to Remediation, Second Edition provides a comprehensive overview of the causes of soil pollution, distribution, transport, and fate of pollutants and transformation of pollutants in soil and metabolite accumulation. Soil pollution has increased over the last decades and may pose a risk for human and ecological health. The book expands and updates on current knowledge with an increased focus on PFAs and micronanplastics. The new edition also includes a new chapter on the One Health initiative.In this book, researchers and students in soil science will find appropriate and comprehensive information on organic, inorganic, and nanoparticle pollutants in soil, methodologies for their monitoring, and data reporting processes in order to gain adequate insights of pollution problems caused by these pollutants.

  • Comprehensive Toxicology

    • 4th Edition
    • Charlene McQueen
    • English
    Comprehensive Toxicology, Fourth Edition, Fifteen Volume Set continues the legacy that began with the first edition in 1997, serving as an indispensable reference for toxicology researchers. This edition focuses on understanding the mechanisms by which chemicals affect biological systems and cause adverse health effects. Edited by a distinguished editorial board and featuring 400 in-depth contributions from experts around the globe, this comprehensive work spans fifteen volumes and nearly 9,000 pages, covering all major organ systems and general principles of toxicology. This extensively revised edition includes around 30 new chapters on modern testing strategies and novel in vitro models, such as organ-on-a-chip systems.It also explores computational approaches, new risk and safety assessment methods, harmonization, artificial intelligence, and the microbiome. As the most authoritative resource in toxicology, it continues to support researchers, faculty, and students in toxicology, as well as professionals in medical, veterinary, food, environmental, chemical, and pharmaceutical industries and international regulatory agencies.

  • Lipid Analysis in Biology, Health, and Disease

    • 1st Edition
    • Sanjoy K. Bhattacharya
    • English
    Lipid Analysis in Biology, Health, and Disease bridges the gap between discovery science and clinical lipidology, empowering both scientific and medical communities to apply lipid analysis and understanding in new research, as well as diagnosis and management of diseases. Here, international experts in the field begin with the basic biology of the lipids, followed by methods and technology for study, and lipids in lab medicine and epidemiology. This book uniquely combines biology and analysis to drive healthcare advances, with a diverse range of technologies and analytic methods considered.Basic lipid biology chapters discuss membrane expansion, lysosomal positioning, mitochondrial biogenesis, lipid-protein interactions, molecular dynamics, cholesterol transport, immune activation and inflammation, lipid droplets, and gender differences in lipid metabolism. Each disease chapter incorporates basic lipid epidemiology, risk factors, and genetic associations.

  • Sustainable Valorization of Date Palm By-products and Wastes

    • 1st Edition
    • Sajid Maqsood + 2 more
    • English
    Sustainable Valorization of Date Palm Byproduct and Wastes provides a comprehensive resource on the sustainable valorization of date byproducts and waste. Composed of 13 chapters, this book highlights the various green technologies and processing methods that can be used to extract valuable compounds from these byproducts and convert them into high-value products, such as biofuels, animal feed, and functional food ingredients. Bringing together contributions from leading experts in the field of food science and technology, this title provides a valuable resource for professionals and researchers in the industry, as well as policymakers, entrepreneurs, and students.Date palm is a significant crop in many regions of the world, producing large quantities of byproducts and wastes that are often underutilized or wasted.

  • Machine Learning and Artificial Intelligence in Toxicology and Environmental Health

    • 1st Edition
    • Zhoumeng Lin + 1 more
    • English
    Machine Learning and Artificial Intelligence in Toxicology and Environmental Health introduces the fundamental concepts and principles of machine learning and AI, providing clear explanations on applying these methods to toxicology and environmental health. The book delves into predictions of chemical ADMET properties, development of PBPK and QSAR models, toxicogenomic analysis, and the evaluation of high-throughput in vitro assays. It aims to guide readers in adapting machine learning and AI techniques to various research problems within these fields. Additionally, the text explores ecotoxicology assessment, impacts of air pollution, climate change, food safety, and chemical risk assessment.It includes case studies, hands-on computer exercises, and example codes, making it a comprehensive resource for researchers, academics, students, and industry professionals. The book highlights how AI can enhance risk assessment, predict environmental hazards, and speed up the identification of harmful substances.

  • Strategies for Sustainable Shrimp Aquaculture

    • 1st Edition
    • Luis Rafael Martínez-Córdova + 1 more
    • English
    Strategies for Sustainable Shrimp Aquaculture explores the varied impacts of shrimp production and the modern approaches to minimizing those impacts. As demand for shrimp grows not only in the food sector, but also in the pharmaceutical, healthcare, and cosmetics sectors, shrimp farming is among the top-growing global aquaculture industries. Given this growth, much research in recent decades has focused on promoting sustainable scale-up of the industry. This book delves into recent advancements in site selection, nutrition, disease prevention, and production systems.Written by a renowned team of shrimp production experts, this book begins by describing relevant considerations of site selection to maximize use of ecosystem services and minimize effluent impacts on surrounding habitats. Early chapters discuss advances in shrimp nutrition and natural feed using phytoplankton, zooplankton, and microorganisms. The book then turns to genetic tools used to protect against disease, as well as advances in disease detection and outbreak control. Final chapters discuss novel shrimp production systems, including low-density systems, multiphase aquaculture, automatic feeding, inland and boutique farms, aquaponics, polyculture, IMTA, and the best strategies for remediation of affected habitats.

  • Complicaciones crónicas de la diabetes mellitus. Perspectivas actuales y nuevas claves fisiopatológicas

    • 1st Edition
    • Didac Mauricio + 1 more
    • Spanish
    Entre las complicaciones de la diabetes se incluyen alteraciones patológicas que suelen relacionarse con el sistema vascular y los órganos diana habituales. Sin embargo, también hay complicaciones menos frecuentes, total o parcialmente independientes de la lesión vascular, que suelen pasarse por alto. Este libro ofrece una visión holística de la enfermedad y aborda no solo sus complicaciones habituales, sino también las afecciones menos conocidas y tratadas que se asocian a la diabetes. También se exponen los avances alcanzados en la comprensión de la arquitectura genómica de las complicaciones de la diabetes y cómo se puede utilizar la medicina de precisión para personalizar el tratamiento. Este libro es una obra exhaustiva sobre el tema, dirigida a endocrinólogos, diabetólogos, médicos de atención primaria e investigadores interesados en las complicaciones de la diabetes y en la información más actualizada al respecto.

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