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Elsevier

Books in Life sciences

  • The Epidermis

    • 1st Edition
    • William Montagna + 1 more
    • English
    The Epidermis documents the proceedings of a symposium that explored in detail the fundamental aspects of the epidermis and the still poorly understood process of keratinization. The Division of Dermatology, University Extension and the School of Medicine of the University of California at Los Angeles agreed to sponsor the conference and offered the University's Residential Conference Center at Lake Arrowhead for the meeting place. This volume is a source book of basic dermatologic thought and information. More than a book of dermatology, this volume makes a singular contribution to our knowledge of keratinization. The volume contains 37 papers and opens with an introductory chapter on keratinization, focusing on the history of the keratohyalin granules, the role of lipids in the orderly keratinization of the epidermis, and the desquamation process. Subsequent chapters present studies on topics such as the behavior of the skin; the effects of various experimental conditions on keratinization in organ culture; and the localization and the regional variability in the concentration epidermal enzymes.

  • Biology of Insect Eggs

    • 1st Edition
    • H. E. Hinton
    • English
    Biology of Insect Eggs is a three-volume account of the biology of insect eggs and covers topics ranging from oviposition and respiratory systems to the respiratory efficiency of egg plastrons. Hydropyles and water relations are also discussed, along with colleterial glands, enemies of insect eggs, and devices used by insects to defend their eggs against enemies. The first volume of this book begins with an overview of a number of controversial points related to insect eggs, such as size of eggs, the kinds of metamorphosis, apolysis and ecdysis, and arrangement of orders of insects. The second volume contains chapters that deal with the structure of the female reproductive system; vitellogenesis; and the development of the micropylar complex. It also provides an account of the eggs of each order of insects, including Ephemeroptera, Orthoptera, and Cheleutoptera as well as Phthiraptera, Hemiptera, and Coleoptera. The third volume is the index to subjects, species, and the bibliography which contains more than 4,000 entries. This monograph will be of interest to biologists and entomologists.

  • Proceedings of the Conference on Nitrogen as a Water Pollutant

    Volume 8.4
    • 1st Edition
    • S. H. Jenkins
    • English

  • Control of Pig Reproduction

    • 1st Edition
    • D.J.A. Cole + 1 more
    • English
    Control of Pig Reproduction focuses on carefully evaluated techniques and technologies involved in the control of pig reproduction. The selection first ponders on the sexual development of male pigs, including early fetal, perinatal, and pubertal periods. The text also discusses testicular steroids and boar taint; interrelationships between spermatozoa, female reproductive tract, and egg investments; and artificial insemination. Discussions focus on androgens, estrogens, deposition of semen and uterine transit, sperm regulation and release by the isthmus, and types of artificial insemination. The manuscript examines endocrine control of sexual maturation in female pigs and sexual differentiation of the stimulatory estrogen feedback mechanism and factors affecting the natural attainment of puberty in gilts. Discussions focus on development of ovarian function and gonadal steroid levels; development of the stimulatory estrogen feedback mechanism; and maturation of negative feedback of gonadal steroids. The text also takes a look at controlled induction of puberty, endocrine control of the estrus cycle, and control of ovulation. The selection is a valuable reference for farmers and readers interested in pig reproduction.

  • Audubon Wildlife Report 1989/1990

    • 1st Edition
    • William J. Chandler
    • English
    Audubon Wildlife Report 1989/1990 covers important challenges to the continued health of different species and ecosystems, furthering the debate on issues such as old-growth forests, the relationship between water and wildlife, and the need to preserve and restore wetlands and grassland range territory. The book starts by providing a comprehensive overview of the featured federal agency, the U.S. Army Corps of Engineers, including its history, legislative mandate, and key programs that affect the environment. The text then discusses federal court decisions that provide new interpretations of federal wildlife law; the conservation of coastal wetlands in the Southeast; and global climate change and its potential effects on fish and wildlife. A monitoring and research strategy for nongame migratory birds, as well as the conservation of ancient forests of the Pacific Northwest are also considered. The book further tackles the restoration of the public rangelands in the West; discard bycatch in marine fisheries with a special focus on the Gulf of Mexico; and the trends in western water law and their implications for the environment. The text also encompasses the appropriations and related congressional policy directives for federal fish and wildlife programs. Biologists and people with an advocacy of preserving wildlife will find the book invaluable.

  • Toxins

    Animal, Plant and Microbial
    • 1st Edition
    • Philip Rosenberg
    • English
    Toxins: Animal, Plant and Microbial is a collection of materials from the proceedings of the Fifth International Symposium on Animal, Plant, and Microbial toxins, held in Costa Rica in August 1976. The book deals with research done on reptiles, arthropods, marine, fresh water, amphibia, plants, bacteria, and multispecies focusing on topics such as biology, anatomy, immunology, bio-chemistry, physiology, and pharmacology. The paper starts with the feeding methods and diet for snakes that will be used for venom collection. Another paper describes the venom apparatus and amount of venom yields of the snake Hydrophiidae. The book also describes the ultrastructure of the skin of the soapfish Grammistes sexlineatus, known to release an irritating substance when threatened or disturbed. One paper presents the effect of toxins derived from the scorpion venom on neuromuscular transmission, while another study describes anti-scorpion serum and antivenin with a corresponding table representing the correct serum dosage. The book then presents a method to use for quantitative separation and analysis of certain mycotoxins that can be present in foodstuffs. One paper also addresses the effects of mycotoxins on immunity levels, such as lowered resistance to diseases, interference with acquired immunity, and changes in antibody production. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology and toxicology will find this book relevant.

  • Modern Approaches to Animal Cell Technology

    • 1st Edition
    • R.E. Spier + 1 more
    • English
    Modern Approaches to Animal Cell Technology is a collection of papers presented at the 1987 joint European Society for Animal Cell Technology-OHOLO conference held in Tiberias, Israel. Contributors explore modern approaches to animal cell technology and discuss the construction of the animal cell substrate, the physiology of those cells in a bioreactor type of environment, and the ways in which different products can be made from animal cells in culture and tested. This book is comprised of 59 chapters divided into nine sections and begins by outlining the history of issues and decisions that were made regarding the acceptability of various cell substrates, along with the use of continuous cell lines in biotechnology. The next chapter explores the feasibility, reproducibility, and the sensitivity of the dot-blot filter hybridization test to detect minute amounts of residual cellular DNA. The reader is then introduced to cells and cell lines such as monoclonal antibodies; cell growth and development; physiology of cells; and the use of bioreactors for culturing animal cells. Downstream unit processes, vaccines, immune system products, and toxicity testing with animal cells are also considered. This monograph will be a valuable resource for animal-cell technologists, biotechnologists, and microbiologists.

  • Audubon Wildlife Report 1987

    • 1st Edition
    • Roger L. Di Silvestro
    • English
    Audubon Wildlife Report 1987 covers important events that highlighted wildlife conservation in 1986. This book is an attempt by the National Audubon Society to gather together much of the diverse data about federal wildlife-policy administration, providing a vast array of data on federal wildlife management and comparative tables on the budgeting process. This text also examines many federal wildlife programs, from the migratory bird protection program, which in a sense gave birth to the federal role in wildlife conservation, to the endangered species program, called as the most important wildlife conservation effort in the world. This publication is valuable to conservationists and individuals interested in federal and state wildlife management.

  • Animal Cell Technology

    Developments, Processes and Products
    • 1st Edition
    • R. E. Spier + 2 more
    • English
    Animal Cell Technology: Developments, Processes and Products is a compilation of scientific papers presented at the 11th European Society for Animal Cell Technology (ESACT) Meeting, held in Brighton, United Kingdom. The book is a collection of various works of scientists, engineers, and other specialists from Europe and other parts of the world who are working with animal cells. The book’s aim is to communicate experiences and research findings on the development of cell systems. The research papers are grouped into 25 sections encompassing 145 chapters. Subjects covered range from cells and physiology engineering dealing with cell characterization, cell culture establishment, cloning, and cell engineering. Topics on culture media, ammonium detoxification, the effects of physical parameters on cell cultures, assays and monitoring systems, and bioreactor techniques are also covered. Discussions are likewise made on the products from animal cells in culture, virus removal, and DNA determination and characterization in relation to safety issues. The book will be useful for cell biologists, molecular biologists, biochemists, biochemical engineers, and students engaged in the study of animal cell cultures.

  • Logan Turner's Diseases of the Nose, Throat and Ear

    • 10th Edition
    • A. G. D. Maran
    • English
    Logan Turner's Diseases of the Nose, Throat and Ear, Volume 10 is intended to serve as a preparatory volume for senior students, general practitioners, and trainees in otolaryngology preparing for a fellowship examination in otolaryngology. The authors of this volume tried not to confine their presentations to pathology in Northern Europe given differences in the presentation of pathology in developed and the developing countries and the popularity of this book in Middle East, the Indian Subcontinent, and South East Asia. This book is organized into four main sections. The first three sections cover the anatomy, physiology, and diseases of the nose, head and neck, and the ear. The final section deals with pediatric otalaryngology. Several changes were made in this tenth volume. These include the presentation of otology, audiology, and otoneurology as an integrated whole; the rewriting of the section of rhinology; addition of a section on pediatric otolaryngology; and modification and expansion of the section on head and neck surgery. This book will be of interest to senior students, general practitioners, and trainees in otolaryngology.

  • Readings in Cognitive Science

    A Perspective from Psychology and Artificial Intelligence
    • 1st Edition
    • Allan Collins + 1 more
    • English
    Readings in Cognitive Science: A Perspective from Psychology and Artificial Intelligence brings together important studies that fall in the intersection between artificial intelligence and cognitive psychology. This book is composed of six chapters, and begins with the complex anatomy and physiology of the human brain. The next chapters deal with the components of cognitive science, such as the semantic memory, similarity and analogy, and learning. These chapters also consider the application of mental models, which represent the domain-specific knowledge needed to understand a dynamic system or natural physical phenomena. The remaining chapters discuss the concept of reasoning, problem solving, planning, vision, and imagery. This book is of value to psychologists, psychiatrists, neurologists, and researchers who are interested in cognition.

  • The Laboratory Rat

    Biology and Diseases
    • 1st Edition
    • Henry J. Baker + 2 more
    • English
    The Laboratory Rat, Volume I: Biology and Diseases focuses on the use of rats in specific areas of research, ranging from dental research to toxicology. The first part of this book retraces the biomedical history of early events and personalities involved in the establishment of rats as a leading laboratory animal. The taxonomy, genetics and inbred strains of rats are also elaborated. The next chapters illustrate the hematology, clinical biochemistry, and anatomical and physiological features of the laboratory rat. This text concludes with a description of infectious diseases that may be contracted from laboratory and/or wild rats. This volume is a good source for commercial and institutional organizations involved in producing rats for research use, specialists in laboratory animal, animal care and research technicians, as well as students in graduate and professional curricula.

  • Probes and Membrane Function

    • 1st Edition
    • Britton Chance + 2 more
    • English
    Probes of Structure and Function of Macromolecules and Membranes, Volume I: Probes and Membrane Function discusses the developments in techniques for the measurement of rapid reactions and detection of enzymatic reactions in simple and complex systems. This book describes the application of the incisive techniques employed for the study of activity-related structural changes in enzymes to functionally related structural changes in membranes. The structural changes initiated in response to energy coupling and ion movements in mitochondria and axons are also elaborated. This publication covers the basic mechanisms by which structural changes can participate in energy coupling at the redox level of the hemoproteins that leads to the evaluation of the function of ubiquinone and cytochrome b in energy coupling. The function of factors that couple electron transport and energy conservation is likewise considered. This volume is a good reference for students and researchers conducting work on the structure and function of macromolecules and membranes.

  • The Evolution of Protein Structure and Function

    A Symposium in Honor of Professor Emil L. Smith
    • 1st Edition
    • David S. Sigman + 1 more
    • English
    The Evolution of Protein Structure and Function documents the proceedings of the symposium ""Evolution of Protein Structure and Function"" held at the Dickson Art Auditorium, University of California Los Angeles (UCLA), 28-29 June 1979. Its objective was to honor Professor Emil L. Smith on the occasion of his retirement as Professor and Chairman, Department of Biological Chemistry, School of Medicine, UCLA. The papers presented by Emil’s colleagues, friends, and students from all phases of his long and varied scientific career provided a valuable review of enzymology, protein chemistry, and biochemical evolution. The volume contains 16 chapters is organized into three parts. Part I contains papers on enyzmology, including the role of the recA protein of Escherichia coli in general recombination; the evolution of enzyme families; and studies on metalloenzymes. Part II takes up protein structure and function. It includes papers on glycoprotein hormones, thymus hormones, chromosome biology and chemistry, and the evolution of histones. Part III examines the evolution of proteins, including the evolution of cythochrome c and evolution of phycobilisome of cyanobacteria and red algae.

  • Tissue Engineering of the Peripheral Nerve: Biomaterials and Physical Therapy

    • 1st Edition
    • Volume 109
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Marine Enzymes for Biocatalysis

    Sources, Biocatalytic Characteristics and Bioprocesses of Marine Enzymes
    • 1st Edition
    • Antonio Trincone
    • English
    Marine bioprospecting is a highly topical subject - in both applied and basic research - but, as yet, the marine ecosystem is a relatively unexplored source of natural bioactive substances with potential therapeutic activity. This book addresses the use of marine enzymes in biocatalysis through a series of chapters from leading scientists within academic and industrial fields. Biocatalytic processes can take advantage of the habitat-related properties of marine enzymes, such as salt tolerance, hyperthermostability... barophilicity, cold adaptivity, and so on, whilst also taking into consideration substrate specificity and affinity. These evolved properties are linked to the metabolic functions of the enzymes and to the ecological aspects of the natural source. New properties can also be discovered at the molecular level of catalysis, particularly concerning the stereochemical characteristics of products.Marine enzymes for biocatalysis initially examines the nature and level of interest in marine biological diversity, and outlines the fundamentals of biocatalysis. It goes on to detail sources of marine enzymes, and to analyse examples from both chemical and stereochemical viewpoints of catalysis, including microbial enzymes and animal or plant sources. The book goes on to explore the future potential of marine bioprospecting in biocatalysis.

  • Diet, Immunity and Inflammation

    • 1st Edition
    • Philip C Calder + 1 more
    • English
    Although inflammation is one of the body’s first responses to infection, overactive immune responses can cause chronic inflammatory diseases. Long-term low-grade inflammation has also been identified as a risk factor for other diseases. Diet, immunity and inflammation provides a comprehensive introduction to immunity and inflammation and the role that diet and nutrition play with regard to this key bodily response.Part one, an introductory section, discusses innate and adaptive immunity, mucosal immunity in a healthy gut and chronic inflammatory diseases and low grade inflammation. Chapters in part two highlight the role of micronutrients, including zinc, selenium, iron, vitamin A and vitamin D, in inflammation and immunity. Part three explores other dietary constituents and includes chapters on intestinal bacteria and probiotics, the impacts of prebiotics on the immune system and inflammation, and antimicrobial, immunomodulatory and anti-inflammatory effects of food bioactive proteins and peptides. Further chapters explore the role of olive oil, short and long chain fatty acids and arginine and glutamine in immune functions. Nutrition, immunity and inflammation are discussed from an integrative and life course perspective in part four. Chapters focus on adverse immune reactions to foods, early nutritional programming, the impact of nutrition on the immune system during ageing, the impact of exercise on immunity and the interaction with nutrition, and the effect that malnutrition has on immunity and susceptibility to infection.With its distinguished editors and international team of expert contributors, Diet, immunity and inflammation is a comprehensive resource for those researching immunology or inflammation, nutrition scientists, and professionals in the food and nutrition industries who require an understanding of the effect that diet can have on the immune system and inflammation.

  • Formulation Tools for Pharmaceutical Development

    • 1st Edition
    • J E Aguilar
    • English
    A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools.Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software.

  • Instrumental Assessment of Food Sensory Quality

    A Practical Guide
    • 1st Edition
    • David Kilcast
    • English
    Instrumental measurements of the sensory quality of food and drink are of growing importance in both complementing data provided by sensory panels and in providing valuable data in situations in which the use of human subjects is not feasible. Instrumental assessment of food sensory quality reviews the range and use of instrumental methods for measuring sensory quality.After an introductory chapter, part one goes on to explore the principles and practice of the assessment and analysis of food appearance, flavour, texture and viscosity. Part two reviews advances in methods for instrumental assessment of food sensory quality and includes chapters on food colour measurement using computer vision, gas chromatography-olfac... (GC-O), electronic noses and tongues for in vivo food flavour measurement, and non-destructive methods for food texture assessment. Further chapters highlight in-mouth measurement of food quality and emerging flavour analysis methods for food authentication. Finally, chapters in part three focus on the instrumental assessment of the sensory quality of particular foods and beverages including meat, poultry and fish, baked goods, dry crisp products, dairy products, and fruit and vegetables. The instrumental assessment of the sensory quality of wine, beer, and juices is also discussed.Instrument... assessment of food sensory quality is a comprehensive technical resource for quality managers and research and development personnel in the food industry and researchers in academia interested in instrumental food quality measurement.

  • Satiation, Satiety and the Control of Food Intake

    Theory and Practice
    • 1st Edition
    • John E Blundell + 1 more
    • English
    With growing concerns about the rising incidence of obesity, there is interest in understanding how the human appetite contributes to energy balance and how it might be affected by the foods we consume, as well as other cultural and environmental factors. Satiation, satiety and the control of food intake provides a concise and authoritative overview of these areas. Part one introduces the concepts of satiation and satiety and discusses how these concepts can be quantified. Chapters in part two focus on biological factors of satiation and satiety before part three moves on to explore food composition factors. Chapters in part four discuss hedonic, cultural and environmental factors of satiation and satiety. Finally, part five explores public health implications and evaluates consumer understanding of satiation and satiety and related health claims.

  • Functional Ingredients from Algae for Foods and Nutraceuticals

    • 1st Edition
    • Herminia Dominguez
    • English
    Algae have a long history of use as foods and for the production of food ingredients. There is also increasing interest in their exploitation as sources of bioactive compounds for use in functional foods and nutraceuticals. Functional ingredients from algae for foods and nutraceuticals reviews key topics in these areas, encompassing both macroalgae (seaweeds) and microalgae.After a chapter introducing the concept of algae as a source of biologically active ingredients for the formulation of functional foods and nutraceuticals, part one explores the structure and occurrence of the major algal components. Chapters discuss the chemical structures of algal polysaccharides, algal lipids, fatty acids and sterols, algal proteins, phlorotannins, and pigments and minor compounds. Part two highlights biological properties of algae and algal components and includes chapters on the antioxidant properties of algal components, anticancer agents derived from marine algae, anti-obesity and anti-diabetic activities of algae, and algae and cardiovascular health. Chapters in part three focus on the extraction of compounds and fractions from algae and cover conventional and alternative technologies for the production of algal polysaccharides. Further chapters discuss enzymatic extraction, subcritical water extraction and supercritical CO2 extraction of bioactives from algae, and ultrasonic- and microwave-assisted extraction and modification of algal components. Finally, chapters in part four explore applications of algae and algal components in foods, functional foods and nutraceuticals including the design of healthier foods and beverages containing whole algae, prebiotic properties of algae and algae-supplemented products, algal hydrocolloids for the production and delivery of probiotic bacteria, and cosmeceuticals from algae.Functional ingredients from algae for foods and nutraceuticals is a comprehensive resource for chemists, chemical engineers and medical researchers with an interest in algae and those in the algaculture, food and nutraceutical industries interested in the commercialisation of products made from algae.

  • Cancer Drug Design and Discovery

    • 2nd Edition
    • Stephen Neidle
    • English
    Cancer Drug Design and Discovery, Second Edition is an important reference on the underlying principles for the design and subsequent development of new anticancer small molecule agents. New chapters have been added to this edition on areas of particular interest and therapeutic promise, including cancer genomics and personalized medicine, DNA-targeted agents and more. This book includes several sections on the basic and applied science of cancer drug discovery and features those drugs that are now approved for human use and are in the marketplace, as well as those that are still under development. By highlighting some of the general principles involved in taking molecules through basic science to clinical development, this book offers a complete and authoritative reference on the design and discovery of anticancer drugs for translational scientists and clinicians involved in cancer research.

  • Tissue Engineering of the Peripheral Nerve

    Stem Cells and Regeneration Promoting Factors
    • 1st Edition
    • Volume 108
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on tissue engineering of the peripheral nerve. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Between the Lines of Genetic Code

    Genetic Interactions in Understanding Disease and Complex Phenotypes
    • 1st Edition
    • Leonid Padyukov
    • English
    Between the Lines of Genetic Code lays out methodologies and tools for the measurement and evaluation of gene-gene and gene-environment studies and gives perspective on the future of this discipline. The book begins by defining terms for interaction studies, describing methodologies, and critically assessing the viability of current study designs and the possibilities for integrating designs. It then provides recent applications data with case studies in rheumatoid arthritis, multiple sclerosis, myositis and other complex human diseases. Last, it examines current studies and directions for future applications in patient care. Recent multivariate studies show that gene-gene and gene-environment interactions can explain significant variances in inheritance that have previously been undetectable in univariate analysis. These links among genes and between genes and their environments during the development of diseases may serve as important hints for understanding pathogenic mechanisms and for developing new tools for prognosis, diagnosis, and treatment of various diseases.

  • Human Reproductive Biology

    • 4th Edition
    • Richard E. Jones + 1 more
    • English
    The fourth edition of Human Reproductive Biology—winner of a 2015 Textbook Excellence Award (Texty) from The Text and Academic Authors Association—emphasiz... the biological and biomedical aspects of human reproduction, explains advances in reproductive science and discusses the choices and concerns of today. Generously illustrated in full color, the text provides current information about human reproductive anatomy and physiology. This expansive text covers the full range of topics in human reproduction, from the biology of male and female systems to conception, pregnancy, labor and birth. It goes on to cover issues in fertility and its control, population growth and family planning, induced abortion and sexually transmitted diseases. This is the ideal book for courses on human reproductive biology, with chapter introductions, sidebars on related topics, chapter summaries and suggestions for further reading.

  • Managing and Leading for Science Professionals

    (What I Wish I'd Known while Moving Up the Management Ladder)
    • 1st Edition
    • Bertrand C. Liang
    • English
    Can technical paradigms help managers lead technical companies? In Managing and Leading for Science Professionals, Bertrand Liang explains that they can, as he explores real issues of importance for technical students and managers who want to move into leadership positions. A CEO with an MBA, Liang originally trained as a neurology and oncology clinician and later earned a PhD in molecular biology and genetics. In this book, he emphasizes what he wishes he had known as he advanced through the organization. His practitioner's point of view is perfectly suited to those who are moving, or want to move, from the technical side to the business side. Focusing on the experiences of scientists and engineers, he teaches ways to speak top management's language. His insights deliver essential knowledge, empowering technical staff to succeed using the skills they know best.

  • Principles of Biomedical Informatics

    • 2nd Edition
    • Ira J. Kalet
    • English
    This second edition of a pioneering technical work in biomedical informatics provides a very readable treatment of the deep computational ideas at the foundation of the field. Principles of Biomedical Informatics, 2nd Edition is radically reorganized to make it especially useable as a textbook for courses that move beyond the standard introductory material. It includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as:• tree structured data, interval trees, and time-oriented medical data and their use• On Line Application Processing (OLAP), an old database idea that is only recently coming of age and finding surprising importance in biomedical informatics• a discussion of nursing knowledge and an example of encoding nursing advice in a rule-based system• X-ray physics and algorithms for cross-sectional medical image reconstruction, recognizing that this area was one of the most central to the origin of biomedical computing• an introduction to Markov processes, and• an outline of the elements of a hospital IT security program, focusing on fundamental ideas rather than specifics of system vulnerabilities or specific technologies. It is simultaneously a unified description of the core research concept areas of biomedical data and knowledge representation, biomedical information access, biomedical decision-making, and information and technology use in biomedical contexts, and a pre-eminent teaching reference for the growing number of healthcare and computing professionals embracing computation in health-related fields. As in the first edition, it includes many worked example programs in Common LISP, the most powerful and accessible modern language for advanced biomedical concept representation and manipulation. The text also includes humor, history, and anecdotal material to balance the mathematically and computationally intensive development in many of the topic areas. The emphasis, as in the first edition, is on ideas and methods that are likely to be of lasting value, not just the popular topics of the day. Ira Kalet is Professor Emeritus of Radiation Oncology, and of Biomedical Informatics and Medical Education, at the University of Washington. Until retiring in 2011 he was also an Adjunct Professor in Computer Science and Engineering, and Biological Structure. From 2005 to 2010 he served as IT Security Director for the University of Washington School of Medicine and its major teaching hospitals. He has been a member of the American Medical Informatics Association since 1990, and an elected Fellow of the American College of Medical Informatics since 2011. His research interests include simulation systems for design of radiation treatment for cancer, software development methodology, and artificial intelligence applications to medicine, particularly expert systems, ontologies and modeling.

  • Nutrition, Aging, and Artificial Organs

    • 1st Edition
    • William I. Gay
    • English
    Methods of Animal Experimentation, Volume V: Nutrition, Aging, and Artificial Organs is a collection of papers that deals with methods to be used in animal experiments to achieve cost effectiveness in their use. This collection discusses laboratory animals used in different experiments such as in nutritional research, aging studies, and artificial organ research. The papers describe the species of animals appropriate for the kind of experiment to be conducted and the criteria that should be followed in choosing a certain species. These criteria include their growth rate, stage of development, as well as existing performance variations. In determining test animals for aging experiments, the book recommends that complete data be available on the genetics of the species, strain, diet history, environmental factors, breeding, and spontaneous diseases to approximate the best test results. The book addresses that the aged are more susceptible to inputs than the young in terms of morphological and functional age. In selecting test animals for artificial organ research, the book notes the importance of animal selection that will be determined, for example, by 1) the size of the prosthesis; 2) the amount of blood flow needed for the device differs in animals and man; and 3) the surgical techniques that will be employed. This book will prove helpful for laboratory workers, veterinarians, and technicians working with laboratory animals. This collection will also be appreciated by researchers designing medical and scientific tests.

  • Physiology of the Cladocera

    • 1st Edition
    • Nikolai N. Smirnov
    • English
    The Physiology of Cladocera is a much-needed summary of foundational information on these increasingly important model organisms. This unique and valuable summary is based on the world's literature, including Russian research not widely available until now. It offers systematically arranged data on the physiology of Cladocera, assisting with explanation of their life and distribution, as well as discussion on directions of future research. Special expert contributions in genetics, immunology, and cytology round out the physiological chapters and provide comprehensive insight into the state of knowledge of Cladocera and its underlying mechanisms. Cladocera crustaceans make up a significant part of the natural communities and biological productivity of fresh waters. In recent decades, they have become globally studied for many purposes, including systematics, genetic, molecular, ecological and evolutionary biology studies. They are also used as "sentinel" organisms for assessing water quality and the environment. In addition, the genome of Daphnia (a genus within Cladocera) was recently sequenced and published, giving this system a much wider exposure. It has also led to a rapidly growing awareness of the importance of understanding physiological processes as they relate to evolutionary and ecological genomics and ecogenomic toxicology. Despite the increasing use of Cladocera in research and study, physiological background information on these creatures is fragmentary. Hundreds of unconnected publications have been accumulated on their physiology, and a synthesis and general representation of the literature has been much needed for the many researchers working with this organism. The Physiology of Cladocera stands alone as a valuable and comprehensive offering in this area for many researchers and students.

  • Plant Biosystematics

    • 1st Edition
    • William F. Grant
    • English
    Plant Biosystematics is a compendium of papers from a symposium titled "Plant Biosystematics: Forty Years Later" held in Montreal in July 1983. This collection reviews the current field of biosystematics, particularly the evolution of natural biota, and how plant biosystematics can contribute to the welfare of humans. One paper reviews biosystematics, compares new approaches, and discusses the latest trend in comparative, molecular evolution of genes. One author discusses the cytology and biosystematics concerning the discontinuities and genetic independence occurring in the evolutionary process. Another author discusses chromosome pairing in species and hybrids that includes models of chromosome pairing in diploids. The text also describes chromosome banding and biosystematics, as well as the problems of chromosome banding that should be addressed to in future research. With estimates of the number of species being threatened with extinction numbering around 20,000 one paper address the issue of conservation and biosystematics. The author suggests that more biological information should be published to avoid duplication of effort, and possibly drive scientists to have their views more widely felt. Agriculturists, botanists, conservationists, environmentalists, and researchers in the field of botany, conservation, and plant genealogy will find this book valuable.

  • Effects of Poisonous Plants on Livestock

    • 1st Edition
    • Richard F. Keeler + 2 more
    • English
    Effects of Poisonous Plants on Livestock documents the proceedings of a U.S.-Australian symposium on the effects of poisonous plants on domestic livestock. The symposium was held at Utah State University in Logan, Utah, on 19-24 June 1977. The volume is organized into eight parts. Part I discusses poisonous plant problems in the United States and Australia. Part II contains papers on general topics such as inorganic toxicants and poisonous plants; the hazard of plant toxicities to the human population; and selenium in plants as a cause of livestock poisoning. Part III examines the effects of simple phytotoxins such as selenium and oxalate on livestock. Part IV focuses on the effects of plant hepatotoxins, including pyrrolizidine alkaloids, Artemisia nova, and Tetradymia spp. Part V deals with plant cardio/pulmonary toxins such as Myoporum spp. and Pimelea spp. Part VI tales up plant neurotoxins while Part VII discusses plant teratogens and toxins affecting reproduction. Part VII presents studies on other toxic substances. It includes studies on oak poisoning and pine needle abortion in cattle.

  • Interleukin 3

    The Panspecific Hemopoietin
    • 1st Edition
    • John W. Schrader
    • English
    Interleukin 3: The Panspecific Hemopoietin contains contributions from immunologists, hematologists, protein chemists, and molecular biologists whose efforts have defined the biology and molecular nature of interleukin 3 (IL-3) in less than a decade. The articles represent personal perspectives rather than exhaustive reviews. They are arranged in alphabetical order rather than thematically because many of the individual articles cover multiple aspects of the molecule. These articles cover topics such as the potential role of IL-3 in the pathology of allergic and inflammatory disease and the role of IL-3 in the genesis of certain myeloid leukemias. A number of articles also highlight an important technical point, namely, that many of the various assays often used for IL-3 are not specific. One article indicates that the ""histamine-producin... cell-stimulating factor"" activity can be mediated not only by IL-3 but also by granulocyte-macropha... colony-stimulating factor. Another deals with the lack of specificity of assays based on the induction of 20α-SDH or factor-dependent cell lines.

  • Plant Resources of Arid and Semiarid Lands

    A Global Perspective
    • 1st Edition
    • J. R. Goodin + 1 more
    • English
    Plant Resources of Arid and Semiarid Lands: A Global Perspective is a collection of papers that evaluates the existing native plant resources in the arid and semiarid regions. The papers deal with the resources found in these arid regions such as food potential, forage, fuel, fiber, medicinal or industrial uses. The book covers the arid regions of Africa, Australia, the Indian subcontinent, Middle East, North America, China, South America, and the USSR. The treatment of these regions includes geographical descriptions such as area, annual precipitation, temperature, humidity, wind ranges or patterns, and seasons. These papers also discuss the effects of topography on water drainage and loss, the basic soil types, holding capacity, water runoffs, and the availability of water (surface and subsurface), The book examines the current and projected growth rates for relevant countries and dry regions in each continent. These papers discuss the economic output from arid lands, the balance of trade, current or developing resources, as well as the prospects of these countries with dry regions. The book also focuses on the types of plants found in these regions whether these are used for food, forage, medicine or for industry. This collection is suitable for environmentalists, ecologists, sociologist, anthropologists, and researchers involved in biological and environmental conservation.

  • The Brain, Cognition, and Education

    • 1st Edition
    • Sarah L. Friedman + 2 more
    • English
    The Brain, Cognition, and Education is a collection of papers that deals with cross-disciplinary communication. This book addresses the use of concepts, methodologies, and research results from other experiments in the conduct of finding new knowledge. One paper addresses the relationships among neuroscience, cognitive psychology, and education to arrive at cross-interdisciplin... communication. Other papers discuss attention, the brain, and the control of cognition; one paper notes that selective attention as a cognitive system with its own measurable features can be associated with underlying neural systems. Other authors deal with acquiring, representing, and using knowledge such as language learning, interplay between mind and experience, as well as the neuropsychology of memory. One paper examines infantile amnesia when early life experiences tend to be forgotten. The book then addresses cognitive and neural development, including neural developments before birth covering neurogenesis, cell migration, dendritic maturation, and synaptic development. One author reviews trends and directions in cognitive development and cites the works of Piaget, Simon, and Chomsky. One author presents several models of memory functions, while another author evaluates the possibilities of building bridges between education and the neurosciences. Many psychologists, neuroscientists, phoneticians, philosophers, and linguists will appreciate this book very highly.

  • Avian Biology

    Volume I
    • 1st Edition
    • Donald S. Farner + 1 more
    • English
    Avian Biology is a collection of papers that deals with biological aspects of birds such as their classification and habitat behavior. One paper reviews how birds are classified through practical systematics, study of fossils, and some of the problems encountered in the arrangement of major groups. Another paper discusses the origin and evolution of birds from their reptilian predecessors to their current evolutionary rates. Evolutionary rates vary depending on access to new habitats; if the environment is static, evolutionary rates can also slow down. One author discusses the inter-relations of sea birds with their marine environment, including coastal areas and the biological properties of the surface water. Another author describes the biology of desert birds relating to nomadism behavior and physical adaptations especially to the arid environment. The author also describes the cooling mechanism of these desert birds. Another paper evaluates the ecological aspect of behavior that includes foraging, habitat selection, mating, and flocking cohesion. Avian biologists, zoologists, and readers who have a general interest in birds will find this book useful.

  • Sexual Selection

    Perspectives and Models from the Neotropics
    • 1st Edition
    • Regina H. Macedo + 1 more
    • English
    Sexual Selection: Perspectives and Models from the Neotropics presents new sexual selection research based upon neotropical species. As neotropical regions are destroyed at an alarming rate, with an estimated 140 species of rainforest plants and animals going extinct every day, it is important to bring neotropical research to the fore now. Sexual selection occurs when the male or female of a species is attracted by certain characteristics such as form, color or behavior. When those features lead to a greater probability of successful mating, they become more prominent in the species. Although most theoretical concepts concerning sexual selection and reproductive strategies are based upon North American and European fauna, the Neotropical region encompasses much more biodiversity, with as many as 15,000 plant and animal species in a single acre of rain forest. This book illustrates concepts in sexual selection through themes ranging from female cryptic choice in insects, sexual conflict in fish, interaction between sexual selection and the immune system, nuptial gifts, visual and acoustic sexual signaling, parental investment, to alternative mating strategies, among others. These approaches distinguish Sexual Selection from current publications in sexual selection, mainly because of the latitudinal and taxonomic focus, so that readers will be introduced to systems mostly unknown outside the tropics, several of which bring into question some well-established patterns for temperate regions.

  • Cell-Associated Water

    Proceedings of a Workshop on Cell-Associated Water Held in Boston, Massachusetts, September, 1976
    • 1st Edition
    • W. Drost-Hansen + 1 more
    • English
    Cell-Associated Water is a collection of papers from the "Cell-Associated Water" Workshop held in Boston in September 1976. This collection discusses aspects of pure colloid, surface science, and zoogeography, with emphasis on cell biology and the role of the aqueous phase of cells. This book starts with a review of the problem of water structure encountered in studying biological systems, particularly as regards the proportion of intracellular water that is actually structured. Another paper discusses the applications of technology in cell biology in understanding cell-associated water, where the dynamic relationship between the state of water and macromolecular events in cellular life exists. This text also examines the possible relationship between water structure and the zoogeographic distribution of some species in aquatic communities using the Prigogine and Glansdorff model approach. This book is recommended for researchers and scientists whose work deals with cellular biology, for graduate students, and academicians in the disciplines of physical and colloid chemistry, cell physiology, biophysics, and molecular biology.

  • Animal Virus Genetics

    • 1st Edition
    • Bernard N. Fields + 1 more
    • English
    Animal Virus Genetics is a collection of scientific presentations of the ICN-UCLA Symposia on Molecular and Cellular Biology, held at the University of California, Los Angeles in 1980. The papers in the compendium focus on the basic genetic model systems; the uses of genetic approaches to study basic problems in molecular biology; and on the increasing application of genetic systems to the study of more complex viral-host interactions such as viral virulence and persistence. Microbiologists, cellular biologists, and virologists will find the book insightful.

  • Photophysiology

    Current Topics in Photobiology and Photochemistry
    • 1st Edition
    • Arthur C. Giese
    • English
    Photophysiology: Current Topics in Photobiology and Photochemistry, Volume VI is a collection of papers that discusses photobiological phenomena found on cells of organisms. The papers in this collection deal with specialized areas of photobiology. One paper describes the instruments used in measuring the course of chlorophyll fluorescence in vivo that occurs when a chlorophyll molecule, stimulated by a light source, returns to its ground state from a previous first singlet state, resulting in a light emission lasting for a few nanoseconds. Another paper discusses the mechanism of light-induced carotenoid synthesis in nonphotosynthetic plants, including temperature-independ... photochemical reactions, which results in the organism's producing carotenoids on subsequent incubations in darkness. One paper also explains photosensitization observed in mutant cells resulting from exposure to specific wavelength of light in the presence of a natural sensitizer. This paper points out that there are four main groups of photosensitizers, namely, the hypericins, chlorophylls, porphyrins, and psoralens. This book can prove valuable for cell biologists, micro-biologists, students, and researchers involved in the fields of photobiology and photochemistry.

  • Proceedings of the First International Conference on Waste Disposal in the Marine Environment

    University of California, Berkeley, July 22-25, 1959
    • 1st Edition
    • E. A. Pearson
    • English
    Proceedings of the First International Conference on Waste Disposal in the Marine Environment focuses on the disposal of sewage, including pollution of beaches, effects of wastes on marine biota and humans, and water quality. The selection first offers information on the fixed and changing valves in ocean disposal of sewage and wastes and characteristics and expeditious detection of bacterial indices of pollution of marine bathing beaches. Discussions focus on the coliform index and illness among bathers; enterococcus group as an index of pollution of saline bathing beaches; characteristics of the coliform group of bacteria; and procedures for expeditious determination of E. coli and coliform indices in water. The book then examines the risk of infection through bathing in sewage-polluted water; water pollution in Marseilles and its relation with flora and fauna; and the benthonic fauna of southern California in shallow depths and possible effects of wastes on the marine biota. The text examines the use of marine invertebrates as indicators of water quality; foraminiferal ecology around ocean outfalls off southern California; discharge of wastes into the sea in European coastal areas; and diffusion of sewage effluent in an ocean. The selection is a dependable reference for readers interested in the effects of waste disposal in the marine environment.

  • Methods for Plant Molecular Biology

    • 1st Edition
    • Arthur Weissbach + 1 more
    • English
    Methods for Plant Molecular Biology is a collection of articles that focuses on the techniques used in plant molecular biology and genetics. The book discusses the isolation and characterization of nuclear, chloroplast, and mitochondrial nucleic acids and the factors and systems involved in transcription and gene expression. Procedures for the isolation of cell walls, chloroplast membranes, membrane proteins; techniques to carry out plant cell culture and protoplast formation; and methods for gene and organelle transfer are covered as well. Biologists, molecular biologists, botanists, and students will find the book very useful.

  • Diseases of the Urethra and Penis

    • 1st Edition
    • E. D'Arcy McCrea
    • English
    Diseases of the Urethra and Penis provides information pertinent to the diseases of the urethra and penis. This book discusses the structure as well as the development of the urethra and penis. Organized into 16 chapters, this book begins with an overview of the anatomy of the penis and urethra. This text then examines the origin of certain developmental abnormalities of the urethra and the penis, including the defects resulting from the polar dichotomy, local malformations, hermaphroditism, and defects due to polar hypogenesis. Other chapters consider the pathology of the various congenital malformations of the urethra and penis. This book discusses as well the etiology, pathology, and treatment of various diseases of the urethra, including acute urethritis, stricture of the urethra, periurethritis, tumors of the urethra, and schistosomiasis of the urethra. The final chapter deals with the etiology, pathology, clinical diagnosis, and treatment of priapism. This book is a valuable resource for physicians.

  • Molecular Regulation of Nuclear Events in Mitosis and Meiosis

    • 1st Edition
    • Robert A. Schlegel + 2 more
    • English
    Molecular Regulation of Nuclear Events in Mitosis and Meiosis presents papers from researchers in various fields engaged in the scientific study of molecular mechanisms involved in the control of nuclear events in meiotic and mitotic cell activity. Various articles in the book discuss a wide range of topics such as the development of cytoplasmic activities that control chromosome cycles during maturation of amphibian oocytes; dynamics of the nuclear lamina during mitosis and meiosis; role of protein phosphorylation in xenopus oocyte meiotic maturation; and cell cycle studies of histone modifications. Molecular and cell biologists, oncologists, and biochemists will find the book invaluable.

  • Groundwater in the West

    • 1st Edition
    • Zachary A. Smith
    • English
    Groundwater in the West covers the use, management, laws, and politics of groundwater in the West. The first chapter provides an overview of important groundwater management and policy issues. Each of the subsequent chapters presents a brief description of the water environment in each of the 19 states and the major groundwater regions in the state. These chapters provide a summary of ground water use and consumption by type of consumption, an examination of groundwater problems in the state, and a summary of groundwater law, administration, and regulations. The chapters conclude with a section summarizing groundwater politics (where appropriate) and an evaluation of future potential groundwater management problems. Hydrologists and people involved in groundwater use, control, and management will find the book invaluable.

  • Hysteria and Related Mental Disorders

    An Approach to Psychological Medicine
    • 1st Edition
    • D. Wilfred Abse
    • English
    Hysteria and Related Mental Disorders: An Approach to Psychological Medicine deals with the problems of diagnosis and their bearing on management and treatment of hysteria and related hysteriform conditions. This book is composed of 16 chapters, and starts with a description of the etiology and psychopathology of hysteria. These topics are followed by intensive discussions on the clinical manifestations and diagnosis of hysteria and related mental disorders, including neurosis, psychosis, schizophrenia, and multiple personality. Other chapters consider the nature of dissociative phenomena from a structural and dynamic point of view, as well as its significance in understanding the etiology of ego disorders. This book also looks into some aspects of language development, the conversion process, and the features of hysteria as a communicative disorder. The last chapters present several medical cases illustrating the differences between conversion hysteria and psychophysiologic autonomic disorder. These chapters also deal with the types of psychotherapy for hysteria. This book is of great value to psychologists, neurologists, clinicians, and psychotherapists.

  • Blood Vessels and Lymphatics

    • 1st Edition
    • David I. Abramson
    • English
    Blood Vessels and Lymphatics focuses on the embryology, anatomy, physiology, pharmacology, biochemistry, and pathology of blood vessels and lymphatics. The selection first offers information on the embryology and gross, microscopic and submicroscopic anatomy, biophysical principles and physiology, and pharmacology and biochemistry of arterial and arteriolar systems. The text then takes a look at the sympathetic innervation of arterial tree. The publication examines microcirculation and the venous system, including the structural basis of microcirculation, exchange of materials across capillary wall, pathology of microcirculation, biochemistry, and pharmacology. The book then elaborates on coronary, pulmonary, and gastrointestinal circulation, blood vessels of the pituitary and the thyroid, and disorders affecting arterial or venous circulation. The selection is a vital source of information for readers interested in the study of blood vessels and lymphatics.

  • Crop Resources

    • 1st Edition
    • David S. Seigler
    • English
    Crop Resources contains papers that were originally presented as a symposium on Crop Resources at the 17th Annual Meeting of the Society for Economic Botany in Urbana, Illinois, 13-17 June 1976. The volume attempts to evaluate (a) the possible nonfood uses of cultivated plants; (b) the extent to which new and additional food resources may become available; (c) the prospects of several specialized uses of plants such as drugs, insecticides, rubber, and condiments; and (d) the origin of four major crops of the American Midwest and prospects for their future development. The discussions include the possibilities of developing new crops from the view of a chemist; the use of currently cultivated oil-seed crops for industrial purposes; the industrial uses of carbohydrates, principally starch and cellulose; the uses of plant materials as medicines; the successes and shortcomings of the Green Revolution; and the uses of plant materials for insecticides. This book should be of interest to anyone with a concern for natural resources, both renewable and nonrenewable. It should be of particular interest to agronomists, horticulturalists, chemists, chemical engineers, botanists, biologists, pharmacognosists, and anthropologists.

  • Isotopes in Biology

    • 1st Edition
    • George Wolf
    • English
    Isotope is Biology is a six-chapter supplementary text that covers the properties and application of isotopes as labels or analytical tools in biological research. The first chapters deal with the physico-chemical properties and radioactivity of isotopes. These chapters also explore their synthesis, preparation, radiation decomposition, and decay of radioactivity. The succeeding chapter considers other aspects of isotopes, including their effect of health, disposal, spills, and laboratory use. Another chapter examines the chemical and biochemical behavior, natural abundance, and the chemical stability of isotopic compounds. The final chapters describe several isotopic methods, namely, isotope dilution, paper chromatography, and autoradiography, with emphasis on their application in biological studies. This book will be of value to biologists, and graduate and undergraduate biology students.

  • Mammalian Protein Metabolism

    Volume III
    • 1st Edition
    • H. N. Munro
    • English
    Mammalian Protein Metabolism, Volume III, provides an overview of the state of knowledge on mammalian protein metabolism. It enlarges and adds depth to the picture of protein metabolism provided by Volumes I and II. The present volume covers two aspects of protein metabolism not specifically considered in the earlier parts of the treatise. First, there is a section of three chapters dealing with changes in protein metabolism during evolution and during growth and development. At its most fundamental level, this part deals in reality with an aspect of regulation of protein metabolism, since differences in metabolism between species and changes occurring during growth are both outward expressions of genetic control mechanisms that determine the form and characteristics of an animal. The other section in this volume is a survey of methods appropriate to the study of protein metabolism in mammals. This part of the work should prove of special interest to investigators who require a critical evaluation of the possibilities and limitations of methods applicable to intact animals.

  • Distribution and Biological Role

    The Chemistry and Biology of Compounds Containing Amino Sugars
    • 1st Edition
    • Endre A. Balazs + 1 more
    • English
    The Amino Sugars: The Chemistry and Biology of Compounds Containing Amino Sugars, Volume IIA: Distribution and Biological Role focuses on the chemistry, physical chemistry, and biochemistry of naturally occurring and synthetically prepared amino sugars and amino sugar-containing molecules, as well as the biological and medical importance of these molecules. The selection first offers information on the distribution of amino sugars in microorganisms, plants, and invertebrates and amino sugars and macromolecules containing amino sugars in liver. Discussions focus on microorganisms, invertebrates, amino sugar composition, catabolism of amino sugars, and metabolic interrelationships between amino sugars and other sugars. The text then takes a look at amino sugars and macromolecules containing amino sugars in kidney and amino sugar-containing compounds in urine. The publication takes a look at glycoproteins in salivary glands, saliva, and sputum; glycosaminoglycans and glycoproteins in skin; and amino sugar-containing compounds in tumors. The text also evaluates glycosaminoglycans in umbilical cord and glycosaminoglycans and glycoproteins in synovial fluid. The selection is a dependable reference for readers interested in the study of amino sugars.

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