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Books in Life sciences

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  • Translational Glycobiology in Human Health and Disease

    • 1st Edition
    • Michelle Kilcoyne + 1 more
    • English
    Along with nucleic acids, proteins, and lipids, carbohydrates stand as one of four main components of cellular architecture. However, glycobiology (or carbohydrate bioscience) is little understood by non-experts, partly because carbohydrates are a complex, diverse class of molecules structurally and functionally. In recent years, advances in computational analytics (glycomics) have allowed us to better interpret and realize the importance of glycobiology in human health and disease, and glycans and their associated processes have been shown to play a significant role across a variety of disease types. As the biomedical sciences continue to adopt multi-omic and precision medicine approaches, a greater understanding of glycobiology is essential for maintaining healthy physiology and advancing disease treatment.Translatio... Glycobiology in Human Health and Disease offers a deep examination of glycobiology for experts and non-experts alike in areas ranging from the role of glycobiology in chronic and infectious diseases to advances in technologies for higher throughput analysis and diagnosis. While keeping human health in the forefront, this book integrates a thorough discussion of glycobiology fundamentals with its growing areas of application and societal impact. With emphasis throughout on the interdisciplinary nature of glycosciences, this book also features perspectives from the health, computational (glycoanalytics), materials, biopharmaceutical, and diagnostic sciences.Disease and speciality areas addressed include gycoimmunology, neuroglycobiology, commensal glycobiology, gut health, regenerative medicine and glycobiology, glycobiology and cancer, congenital disorders of glycosylation, infectious disease glycobiology, and parasite glycobiology. Computational approaches discussed, supporting the advance of new research, include advanced glycoanalytics, glycomics microarrays, glycoengineering, and glycol systems biology. Additionally, authors consider impact areas for society and public health, such as glycobiology and entrepreneurship, policy and regulatory requirements for glycosylation, future research, and translation to new diagnostics and drug discovery.

  • Steroid Hormone Receptors in Health and Disease

    • 1st Edition
    • Raj Kumar + 1 more
    • English
    Steroid Hormone Receptors in Endocrine Physiology and Diseases covers the role of steroid hormones in human physiology and receptor activity in the pathophysiology of disease. The book discusses how these receptors can be used as therapeutic targets for the treatment of conditions from cancer to aging, offering immediate applications of biochemical principles into clinical applications such as diagnosis and treatment. This book is a valuable reference for graduate and postdoctoral scientists but is also ideal for medical students interested in the functional role of various steroid hormone receptors in a wide variety of endocrine related diseases.Steroid hormone receptors (SHRs) are known to play vital roles in normal physiology through the control of development, differentiation, metabolic homeostasis and reproduction. Due to their involvement in various pathological and disease conditions, SHRs are also important therapeutic targets in several disorders including inflammation, autoimmune diseases, hormone-dependent cancers, osteoporosis and cardiovascular diseases.

  • Silver Nanoparticles for Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Silver Nanoparticles for Drug Delivery is a complete reference that provides comprehensive coverage of the principle behind the formation, characterization, application, regulation, toxicity, and challenges and future perspectives of silver nanoparticles in drug delivery for the treatment of various diseases. Sections cover the synthesis and characterization of silver nanoparticles (AgNPs), historical introductions to developments, methods and characterization parameters, green and biological synthesis methods, biofate and cellular interactions of AgNPs, drug delivery for the treatment of several diseases and conditions, targeting strategies, applications in cancer diagnosis and treatment, and much more. This is a complete reference for graduate students in nanotechnology drug delivery.

  • Gold Nanoparticles for Drug Delivery

    • 1st Edition
    • Prashant Kesharwani
    • English
    Gold Nanoparticles for Drug Delivery discusses the synthesis and characterization of gold nanoparticles (AuNPs), presenting an historical introduction to the developments in the area, discussing methods and characterization parameters, covering targeted delivery strategies, treatment of cancer, CNS conditions, infectious diseases, HIV/AIDS infection, wound healing and tissue regeneration, dentistry, gene delivery, and its photo properties used in diagnostic and therapies, and finally presenting regulatory aspects such as theranostic applications, vaccine development, toxicity, and the translation of research to marketable products. This book is a complete reference for researchers in nanotechnology drug delivery and pharmaceutical disciplines. Researchers in pharmaceutical industries, especially those involved in the use of gold nanoparticles in the field of drug delivery, diagnosis, targeted and early therapies will also benefit from this book.

  • Insects as Food and Food Ingredients

    Technological Improvements, Sustainability, and Safety Aspects
    • 1st Edition
    • Marco Garcia-Vaquero + 1 more
    • English
    Insects as Food and Food Ingredients: Technological Improvements, Sustainability, and Safety Aspects addresses the use of insects as food by following a farm-to-fork approach and covering general aspects concerning farming, processing and the main applications of insects and insect derived ingredients in the food sector. Broken into three sections, this book addresses insect farming, the challenges of processing whole insects, or their fractionation into insect ingredients by the means of conventional and innovative technologies, as well as the biological properties, application, safety, functionality and nutritional value of both insects and their ingredients for food applications. Nutrition researchers, nutritionists, food scientists, health professionals, agricultural researchers, biosystem engineers and those working in or studying related disciplines will benefit from this reference.

  • Resilience and Riverine Landscapes

    • 1st Edition
    • Martin Thoms + 1 more
    • English
    Resilience and Riverine Landscapes presents contributed chapters from global experts in Riverine Landscapes, making it the most comprehensive reference available on the topic. The book explores why rivers are ideal landscapes to study resilience and why studying rivers from a resilience perspective is important for our biophysical understanding of these landscapes and for society. The book focuses on the biophysical character of resilience in riverine landscapes, providing an interdisciplinary perspective of the structure, function, and interactions of riverine landscapes and the ecosystems they contain. The editors conclude by proposing a research agenda for the future, emphasizing the need for transdisciplinary research across a range of spatial and temporal scales and research domains.

  • Stem Cells

    An Alternative Therapy for COVID-19 and Cytokine Storm
    • 1st Edition
    • Yogesh Kumar Verma + 4 more
    • English
    Stem Cells: An Alternative Therapy for COVID-19 and Cytokine Storm provides mechanistic insights into the role of stem cells to combat COVID-19 outbreak and other pathologies where cytokines storm is the cause of concern for e.g., radiation exposure, multiple organ failure and sepsis. There has been an increase in number of cases of new diseases in the last decade, including mucormycosis, Zika virus, H1N1 influenza virus, among others. These diseases can be characterized by the induction of cytokine storm, which is mainly responsible for morbidity and mortality.Stem cell therapy has emerged as a potential treatment for viral diseases, including, but not limited to, COVID-19. Interestingly, clinical trials in patients with COVID-19 complications depicted faster recovery in patients post mesenchymal stem cells therapy owing to the decreased cytokines levels, anti-viral effects and regeneration of the infected tissue.

  • Biofortification of Grain and Vegetable Crops

    Molecular and Breeding Approaches
    • 1st Edition
    • Muhammad Tehseen Azhar + 3 more
    • English
    Biofortification of Grain and Vegetable Crops: Molecular and Breeding Approaches is a comprehensive overview of important food crops whose vitamin and mineral enhancement can contribute significantly to improved food and nutrition security. Providing the latest information on crops including cereals, oilseeds, legumes and vegetables, this book provides details of agronomic and molecular resources for enhanced mineral production. Each chapter focuses on a specific food crop and the unique opportunities offered by each through breeding practices. This will be a valuable resource for researchers, academics and those in industry who are exploring biotechnological approaches as a powerful tool to combat malnutrition.

  • The Role of Tropics in Climate Change

    Global Case Studies
    • 1st Edition
    • Neloy Khare
    • English
    The Role of Tropics in Climate Change: Global Case Studies uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices. The book further explains newly developed techniques for sequencing DNA, generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time.

  • Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine

    • 1st Edition
    • J. Miguel Oliveira + 2 more
    • English
    Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobi... and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related injuries that can affect muscles, bones and joints and lead to severe complications of the neuromuscular system, it is imperative to develop new treatment strategies to delay or repair associated diseases and to promote optimal long-term health.

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