Advances in Biomembranes and Lipid Self-Assembly
- 1st Edition, Volume 38 - November 27, 2023
- Editors: Aleš Iglič︎, Michael Rappolt, Patricia Losada Perez
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 9 2 4 6 - 6
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 9 2 4 7 - 3
Advances in Biomembranes and Lipid Self-Assembly, Volume 38 in this updated series, highlights new advances in the field, with this new volume presenting interesting chapte… Read more
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Request a sales quoteAdvances in Biomembranes and Lipid Self-Assembly, Volume 38 in this updated series, highlights new advances in the field, with this new volume presenting interesting chapters on Interaction of inorganic debris particles with cells, Interactions between biomembrane embedded nanoparticles mediated by lipid bilayer, Topological defect driven nanoparticle assemblies, and more.
- Provides the authority and expertise of leading contributors from an international board of authors
- Presents the latest release in Advances in Biomembranes and Lipid Self-Assembly
- Updated release includes the latest information on the Interaction of inorganic debris particles with cells, Interactions between biomembrane embedded nanoparticles mediated by lipid bilayer, and more
Everyone interested in the strategy and practice of the preclinical phases of the creation of new medicines. Those wishing to understand the drivers of drug design or expand their knowledge of therapeutic target classes
- Cover image
- Title page
- Table of Contents
- Series Page
- Copyright
- Contributors
- Preface
- Chapter One: Interaction of inorganic debris particles with cells
- Abstract
- 1 Introduction
- 2 Methods
- 3 Results
- 4 Oxidative stress of the treated HUVEC cells
- 5 Cytotoxicity
- 6 Discussion
- 7 Conclusions
- References
- Chapter Two: Interactions between biomembrane embedded nanoparticles mediated by lipid bilayer
- Abstract
- 1 Introduction
- 2 The key role of nanoparticle hydrophobicity
- 3 Size matters
- 4 Nanoparticles-mediated effect on the membrane
- 5 Membrane-mediated effects on NP aggregation
- 6 Conclusions
- References
- Chapter Three: Exploring interactions between lipid membranes and nanoparticles through neutron and X-ray reflectometry techniques
- Abstract
- 1 Introduction
- 2 Nanoparticles and planar membranes: Adsorption, penetration and fusion processes seen by reflectometry techniques
- 3 Effect of membrane and nanoparticle complexity
- 4 Towards more complex modeling approaches: Determination of the interaction distance between NPs and a membrane
- 5 Conclusions
- References
- Chapter Four: Role of the nanoparticle core and capping on the interaction with lipid monolayers
- Abstract
- Abbreviations
- 1 Introduction
- 2 Langmuir monolayers as models of biological membranes
- 3 Thermodynamics of Langmuir monolayers
- 4 Self-assembly of nanoparticles at the air/water interface
- 5 Experimental approaches to study nanoparticles and nanoparticles–lipids at the air/water interface
- 6 Case study: Hydrophobic, amphiphilic, and hydrophilic nanoparticles at the air/water interface
- 7 Case study: Interaction of hydrophobic, amphiphilic, and hydrophilic nanoparticles with lipid model membranes at the air/water interface
- 8 Scope, limitations, and perspectives of Langmuir monolayers as membrane models
- Acknowledgments
- References
- Chapter Five: Theoretical description of particle sedimentation in blood considering hematocrit: A 2nd generation mathematical model
- Abstract
- 1 Introduction
- 2 Theory
- 3 Experimental methods
- 4 Results
- 5 Discussion
- 6 Conclusion
- Acknowledgments
- References
- No. of pages: 318
- Language: English
- Edition: 1
- Volume: 38
- Published: November 27, 2023
- Imprint: Academic Press
- Hardback ISBN: 9780323992466
- eBook ISBN: 9780323992473
AI
Aleš Iglič︎
Aleš Iglič received his B.Sc. and Ph.D. degrees in physics and M.Sc. degree in biophysics from the Department of Physics, and the Ph.D. degree in electrical engineering from the Faculty of Electrical Engineering, all from the University of Ljubljana. He is a Full Professor and the Head of Laboratory of Biophysics of the Faculty of Electrical Engineering at University of Ljubljana. His main research interests are in electrostatics, mechanics and statistical physics of lipid nanostructures and biological membranes. He is devoted to higher education, basic research in biophysics and close contacts to clinical practice. Prof. Iglič was visiting scientist and professor at Åbo Academy University in Turku (Finland), Friedrich Schiller University in Jena (Germany) and Czech Technical University in Prague (Czech Republic). He established collaborations with researchers from different universities across the Europe, USA and India and was supervisor of many M.Sc., Ph.D. and postdoctoral students from Slovenia, Czech Republic, Poland, Iran, Bulgaria, Germany, India and Israel. Since 2009 is the editor of Elsevier book series »Advances in Planar Lipid Bilayers and Liposomes« (APLBL).
Affiliations and expertise
Full Professor and Head of Laboratory of Biophysics, Faculty of Electrical Engineering, University of Ljubljana, SloveniaMR
Michael Rappolt
Michael Rappolt has been appointed as Professor of Lipid Biophysics (School of Food Science and Nutrition) in April 2013. He received his MSc and PhD in physics from the University of Hamburg and achieved his habilitation at the University of Ljubljana in the Faculty of Health Sciences. He was Senior Researcher at the Synchrotron Trieste Outstation (Italy), Institute of Biophysics and Nanosystems Research (Austrian Academy of Sciences), before becoming Assistant Professor at Graz University of Technology. Professor Michael Rappolt is a leading authority on investigating the structure and dynamics of lipid membranes using small-angle X-ray scattering. His recent research activities have concentrated on the study of drug/membrane interactions with potential applications to drug delivery and food. Further research topics concentrate on characterising crystallization processes in food, the investigation of colloid interfaces and the determination of particle structures on the nanoscale. He also seeks to transfer standard measurement techniques applied in food research – such as mechanic (sound and shear) and thermodynamic sample manipulations to synchrotron sites – to understand food on a smaller (nanometre) and faster (microsecond) scale.
Affiliations and expertise
Professor of Lipid Biophysics, University of Leeds, UKPL
Patricia Losada Perez
Ana Garcia-Saez gained her PhD at the Department of Biochemistry and Molecular Biology, University of Valencia, Spain in 2005, and then worked as a Post-doc at BioTec, TU Dresden, Germany. From 2013, she was a professor at the Interfaculty Institute for Biochemistry (IFIB), Universität Tübingen, Germany before moving to University of Cologne as a professor in October 2019. Since 2010, Ana was also the Max Planck Research Group’s Leader and the Deutsches Krebsforschungzentrum (DKFZ) Junior Group’s Leader at Bioquant, Heidelberg, Germany, from 2010 to 2013, and has been a Young Investigator as part of the EMBO Young Investigator Programme since 2017.
Ana Garcia-Saez’s research areas include Cell Death & Biophysics, Molecular and Cellular Biology, and Biochemistry & Advanced Microscopy. Though she is also involved in and takes an active interest in Membrane organization, apoptosis regulation, Bcl-2 proteins, membrane dynamics, biophysics, and single molecule techniques. She has received numerous fellowships and awards, including the European Research Council (ERC) Starting Grant, the Max-Planck Gesellschaft Postdoctoral scholarship, and the Marie Curie Intra European fellowship, among others, and has been widely published in the field of membrane biochemistry.
Affiliations and expertise
Professor, University of Cologne, GermanyRead Advances in Biomembranes and Lipid Self-Assembly on ScienceDirect