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1371-1380 of 14737 results in All results

Lantibiotics as Alternative Therapeutics

  • 1st Edition
  • February 17, 2023
  • Sanket Joshi + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 9 1 4 1 - 4
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 1 4 2 - 1
Lantibiotics as Alternative Therapeutics explores alternative therapeutics, lantibiotics and other novel drugs. This book provides concrete information to readers regarding lantibiotics and various types of antimicrobial peptides with their mode of actions in treating various multidrug resistant organisms. It explains various techniques that are involved in analyzing antimicrobial peptides and their mode of actions. The development of antibiotic resistance has now reached a point of crisis where innovative methods and application of novel compounds and methods are required to prevent the spread of drug resistant infections. Novel compounds exhibit different modes of action to the currently used mechanism of therapeutics in order to combat against the resistant organisms. Lantibiotics hold considerable potential as a consequence of their unusual structure, unique mechanisms of action and their potency against multi-drug resistant bacteria. This book will be useful for pharmaceutical industry scientists and researchers in microbial and biomedical research as well as graduate and advanced students in microbiology, medical biotechnology, health, and pharmaceutical sciences.

Recent Developments in Anti-Inflammatory Therapy

  • 1st Edition
  • February 17, 2023
  • Parteek Prasher + 4 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 9 9 8 8 - 5
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 1 6 - 1
Advances in Anti-inflammatory Therapy explores the cutting-edge in anti-inflammation therapy in clear and concise language, with insights from academia and industry. Sections cover key regulatory pathways that mediate acute and chronic inflammation and disease onset. Further chapters are devoted to advanced anti-inflammatory pharmaceuticals, including chemical moieties, pharmacophores, APIs, natural products, herbal therapies, molecular nanomedicine and advanced drug delivery vectors. Systematically planned chapters and illustrations enable potential readers to gain essential insights on the most recent advancements in the field. Arranged with systematic chapters covering a broad range of inflammatory diseases, discussions on past, current and future therapeutics and advanced anti-inflammatory pharmaceuticals, this book will be useful to a wide range of researchers, especially medicinal chemists, drug design experts, and biological and translational researchers working in the field of inflammation.

The Thinking Healthcare System

  • 1st Edition
  • February 17, 2023
  • Dominique J Monlezun
  • English
  • Paperback
    9 7 8 - 0 - 4 4 3 - 1 8 9 0 6 - 7
  • eBook
    9 7 8 - 0 - 4 4 3 - 1 8 9 0 7 - 4
The Thinking Healthcare System: Artificial Intelligence and Human Equity is the first comprehensive book detailing the historical, global, and technical trends shaping the evolution of the modern healthcare system into its final form—an AI-driven thinking healthcare system, structured and functioning as a global digital health ecosystem. Written by the world’s first triple doctorate trained physician-data scientist and ethicist, and author of three AI textbooks and over 350 scientific and ethics papers, this indispensable resource makes sense of how technology, economics, and ethics are already producing the future’s health system—and how to ensure it works for every patient, community, and culture in our globalized, digitalized, and divided world. Providing clear descriptions and concrete examples, this book brings together AI-accelerated digital health ecosystems, data architecture, cloud and edge computing, precision medicine, public health, telemedicine, patient safety, health political economics, multicultural global ethics, blockchain, and quantum health computing, among other topics. Healthcare and business executives, clinicians, researchers, government leaders, policymakers, and students in the fields of healthcare management, data science, medicine, public health, informatics, health and public policy, political economics, and bioethics will find this book to be a groundbreaking resource on how to create, nourish, and lead AI-driven health systems for the future that can think, adapt, and so care in a manner worthy of the world’s patients.  

Urgencias en endocrinología

  • 1st Edition
  • February 17, 2023
  • Alexander L. Shifrin
  • Spanish
  • eBook
    9 7 8 - 8 4 - 1 3 8 2 - 2 7 0 - 9
Guía a los médicos sobre cómo reconocer, diagnosticar y tratar cada trastorno utilizando técnicas diagnósticas y tratamientos actualizados. Presenta una cobertura actualizada y en color de temas clave como la tirotoxicosis aguda y la tormenta tiroidea, el coma mixedematoso, las urgencias oculares en la oftalmopatía de Graves, la parálisis periódica tirotóxica, la cetoacidosis diabética, las crisis hiper- e hipocalcémica, el hipopituitarismo, la diabetes insípida, la apoplejía hipofisaria, el síndrome carcinoide, las urgencias quirúrgicas tiroideas postoperatorias, el feocromocitoma y muchos más. Incorpora capítulos específicos sobre urgencias relacionadas con los tumores neuroendocrinos, las endocrinopatías asociadas a inmunoterapia, y las respuestas endocrinas en pacientes en estado crítico y con traumatismos, además de capítulos sobre las urgencias endocrinas durante el embarazo y la ingesta de yoduro de potasio en emergencias nucleares. Cuenta en cada capítulo con información sobre generalidades, síntomas, diagnóstico y tratamiento. Incluye la versión digital de la obra original (contenido en inglés), con acceso, a través de distintos dispositivos, al texto, las figuras y la bibliografía completa del libro.

Precision Medicine in Neurodegenerative Disorders

  • 1st Edition
  • Volume 193
  • February 16, 2023
  • Alberto J. Espay
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 8 5 5 5 5 - 6
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 0 6 5 - 2
Precision Medicine in Neurodegenerative Disorders, Part Two, Volume 193  in the Handbook of Clinical Neurology deals with the "How" in the reconfiguration of our approach to slow accelerated brain aging. The book rethinks  animal models on which therapies are tested, outlines the progress and expected changes in biological subtyping efforts using lysosomal, endosomal, mitochondrial, immune dysregulation, and inflammatory mechanisms of disease pathophysiology, and the growing role of microbiome in shaping disease. The volume separates the potentially disease-modifying neurorescue and neurorestoration, (e.g., gene therapy and cell replacement therapy) from true precision "medicine"–matching biology with the mechanism of intervention of interest. Specific chapters are dedicated to the promise and challenges of extracellular vesicles for both diagnosis and treatment, the growing application of digital measures and other evaluations of clinical response, the nuts and bolts of novel adaptive clinical trial designs, and the regulatory changes needed to facilitate drug development for disease-modification purposes.

Neurología elemental

  • 3rd Edition
  • February 16, 2023
  • Fernando Barinagarrementeria Aldatz + 3 more
  • Spanish
  • eBook
    9 7 8 - 8 4 - 1 3 8 2 - 4 3 7 - 6
Esta tercera edición, Auspiciada por la Academia Mexicana de Neurología, supone la consolidación de este texto como referencia de la especialidad. Para ello se ha mantenido la estructura clara y se ha actualizado toda la información necesaria para que el estudiante domine la exploración, el diagnóstico y el tratamiento de las enfermedades neurológicas más habituales. Asimismo, incorpora contenido online que consiste en casos clínicos que han sido completamente renovados y presentaciones que han sido actualizadas. La obra va dirigida a estudiantes, pero también puede ser útil para residentes de la especialidad y para médicos no neurólogos que deseen repasar conceptos básicos sobre enfermedades neurológicas comunes. Además, se ha renovado el panel de autores, manteniendo la pluralidad de universidades de origen.  

The Chlamydomonas Sourcebook

  • 3rd Edition
  • February 15, 2023
  • Arthur Grossman + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 2 1 4 3 0 - 5
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 0 5 8 - 3
Originally published as the stand-alone Chlamydomonas Sourcebook, then expanded as the second volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Organellar and Metabolic Processes has been fully revised and updated to include a wealth of new knowledge and resources for the Chlamydomonas community. It details the tremendous progress recently made with respect to imaging the ultrastructure of cells, dissecting acclimation and biosynthetic responses, and elucidating molecular processes underlying the biology of organelles. In particular, this volume includes exciting new developments in the use of imaging technologies for examining supramolecular organization of the chloroplast, defining mechanisms of branched electron transfer pathways in photosynthesis, dissecting the organization of pyrenoids and CO2 concentration mechanisms, presenting the intricacies associated with acclimation to environmental conditions and providing new insights into dark metabolism and the network of fermentative metabolism. This book thus presents the latest advances in both the research and uses of new experimental approaches and technologies, making this a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, aspects of human disease, acclimation to environmental change, and the biogenesis of cellular complexes.

The Chlamydomonas Sourcebook

  • 3rd Edition
  • February 15, 2023
  • Ursula Goodenough
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 2 2 4 5 7 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 2 4 5 8 - 8
The Chlamydomonas Sourcebook, 3rd Edition Introduction to Chlamydomonas and Its Laboratory Use (Volume 1)   The gold-standard reference covering the basic biology of the Chlamydomonas alga and techniques for its laboratory analysis     Originally published as the standalone Chlamydomonas Sourcebook, then expanded as the first volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Introduction to Chlamydomonas and Its Laboratory Use has been fully revised and updated to include a wealth of new resources for the Chlamydomonas community. Early chapters cover current understandings of its taxonomy, ultrastructure, cell and life cycles, and nuclear and organelle genomes, followed by technique-oriented chapters covering such topics as cell culture, mutagenesis, genetic analysis, construction of mutant libraries, and protein localization using immunofluorescence.     This volume presents the latest in research and best practices, making it a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, and biochemistry; crop scientists; plant physiologists; and plant, molecular, and human disease biologists.

The Chlamydomonas Sourcebook

  • 3rd Edition
  • February 15, 2023
  • Susan Dutcher
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 2 2 5 0 8 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 2 5 0 9 - 7
The Chlamydomonas Sourcebook, 3rd Edition Cell Motility and Behavior (Volume 3)   The gold-standard reference introducing this multidisciplinary science, fully revised and updated with the latest discoveries   Originally published as the standalone Chlamydomonas Sourcebook, then expanded as the third volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Cell Motility and Behavior has been fully revised and updated to include the wealth of new resources for the Chlamydomonas community. Reflecting the significant advancement in the understanding of the role of basal bodies and cilia play in human diseases, this volume employs quantitative proteomics and mass spectroscopy as well as cryo EM tomography and single particle cryo EM. Other topics such as current insights on mitosis and cytokinesis, ciliary assembly and motility, intraflagellar transport, and more help build an understanding of human diseases of the cilium.   Cell Motility and Behavior presents the latest in research and best practices, making this a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, and biochemistry; crop scientists; plant physiologists; and plant, molecular, and human disease biologists.

Atomic Force Microscopy for Nanoscale Biophysics

  • 1st Edition
  • February 15, 2023
  • Mi Li
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 5 3 6 0 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 8 3 3 - 2
Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.

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