An Introduction to the Microbiome in Health and Diseases
- 1st Edition - April 22, 2024
- Imprint: Academic Press
- Editors: Charles Oluwaseun Adetunji, Olugbenga Samuel Michael, N. Esiobu, Rotimi E. Aluko
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 1 1 9 0 - 0
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 4 7 2 - 7
The gut microbiome plays a very important role in your health. It controls digestion and has a beneficial impact on your immune system and other aspects of health. An In… Read more
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Request a sales quoteThe gut microbiome plays a very important role in your health. It controls digestion and has a beneficial impact on your immune system and other aspects of health. An Introduction to the Microbiome in Health and Diseases is a prelude to subsequent books on this topic which provides in-depth coverage on the microbiome from basic to clinical microbiology.
This introductory volume offers an overview on the microbiome and explores the role of the human microbiome in health and disease outcomes. It examines the compositional structure and molecular approaches to microbiome characterization and identification. Additional coverage also includes an introduction to animal microbiomes, plant microbiomes, epigenetic programming, gut microbiota and the impact of diet and exercise, as well as the relationship between the microbiome and COVID-19.
This introductory volume offers an overview on the microbiome and explores the role of the human microbiome in health and disease outcomes. It examines the compositional structure and molecular approaches to microbiome characterization and identification. Additional coverage also includes an introduction to animal microbiomes, plant microbiomes, epigenetic programming, gut microbiota and the impact of diet and exercise, as well as the relationship between the microbiome and COVID-19.
- Provides fundamental coverage on the microbiome and its effect on human health and diseases.
- Describes procedures for sampling small and larger samples of the microbiome.
- Discusses patents, bioproducts, commercialization, and the social, ethical and economic implications of the microbiome.
Researchers, clinicians, and students in the field of microbiology at the graduate level and above, including those working in academic, corporate, or non-profit settings, medical/scientific management, and pharmaceutical companies
- Cover image
- Title page
- Table of Contents
- Copyright
- Contributors
- Chapter 1. Microbiome: Introduction and recent advances
- Introduction
- Microbiome and diseases
- The medical relevance of microbiome in the health sector
- Chapter 2. Why the need for microbiome? An updated perspective
- Introduction
- Microbiome and Metabolism
- Lipid metabolism
- Protein metabolism
- Microbiome and the environment
- Gut microbiome and its metabolites
- Microbiome and health
- Maternal microbiome and fetal health
- Microbiome and metabolic health
- Microbiome and cardiovascular health
- Microbiome in agriculture and food industry
- Relationship between plants and microbiome
- Microbiome as a source of novel therapeutics
- Conclusion
- Chapter 3. Procedures for sampling of small and larger samples of microbiome
- Introduction
- General overview
- Sampling of microbiomes
- Fecal microbiome sample collection
- Endoscopy
- Colonic lavage fluid
- Swallowable sampling devices
- Conclusion
- Chapter 4. Microbiome characterization and identification: key emphasis on molecular approaches
- Introduction
- Microbiome characterization and identification
- Microbiome characterization using nucleic acid–based molecular techniques
- Microbiome characterization using omics approaches
- Microbiome characterization: the landscape of genome and transcriptome
- Microbiome characterization: impact of sequencing and bioinformatics tools
- Drawbacks of microbial phenotypic typing
- Understanding the microbial genome and sequencing
- Understanding microbial diversity
- Next-generation sequencing techniques for the microbiome
- NGS techniques of microbiomes
- 16S/18S/ITS rDNA amplicon sequencing
- Metagenomic shotgun sequencing
- Conclusion
- Chapter 5. COVID-19 and microbiome
- Introduction
- Covid-19, ACE2, and microbiome
- COVID-19 and fecal microbiome transplantation
- Microbiome and severity of COVID-19
- Microbiome and hypertension in COVID-19
- Gut microbiota, immune response, and COVID-19
- Neonatal microbiome and COVID-19
- Probiotics and COVID-19
- Butyrate and COVID-19 management
- Gut microbiome and COVID-19-associated gastrointestinal dysfunctions
- Summary and conclusion
- Chapter 6. Introduction to plant microbiome
- Introduction
- Determination of plant microbiomes
- Environmental factors and microbiomes
- Anthropogenic factors and plant microbiomes
- Challenges, future perspectives, and conclusion
- Chapter 7. Introduction to animal microbiome
- Introduction
- Rumen and microbiomes
- Bird gut and microbiomes
- Microbiome in captive and wild animals
- Omics in animal microbiome analysis
- Animal microbiome
- Conclusion
- Chapter 8. Patents, bioproducts, commercialization, social, ethical, and economic policies on microbiome
- Introduction
- Microbiome patents
- Microbiome biproducts
- Social and ethical concerns of microbiome research
- Microbiome commercialization
- Economic impact on microbiome
- Conclusion
- Chapter 9. Introduction to gut microbiome and epigenetics: Their role in polycystic ovary syndrome pathogenesis
- Introduction
- Overview of PCOS
- Gut microbiota dysbiosis in polycystic ovary syndrome
- Altered gut microbial communities in PCOS
- Epigenetics mechanisms and gut microbiota
- Role of diet in microbiota composition and epigenetics
- Transgenerational inheritance of PCOS: role of epigenetics
- Interplay between epigenetic mechanisms and PCOS
- Summary and conclusion
- Chapter 10. Introduction to epigenetic programming by gut microbiota
- Introduction
- Epigenetics of bacterial infections
- The process involved in the host acetylation system by bacteria
- Regulation of histone acetylation
- Gut microbiome and epigenetic regulations
- Epigenetic machineries and the microbiome
- Gut microbiome: Before or after birth?
- Microbiota–immune regulation–epigenetics axis
- Diet, gut microbiota, and epigenetic regulation
- The involvement of microbiota in immune regulation
- Conclusion
- Chapter 11. Gut microbiota, nutrition, and health: Fundamental and basic principle
- Introduction
- Diet and gut microbiota
- SCFAs, gut-derived and exogenous
- Gut dysbiosis
- Analytical approach for gut microbiota identification
- Microbiota applications in health and disease
- Conclusion
- Index
- Edition: 1
- Published: April 22, 2024
- No. of pages (Paperback): 246
- No. of pages (eBook): 266
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780323911900
- eBook ISBN: 9780323914727
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Charles Oluwaseun Adetunji
Prof. Charles Oluwaseun Adetunji is a full Professor at the Department of Microbiology, Faculty of Sciences and the Director of Research and Innovation, Edo State University Uzairue (EDSU), Edo State, Nigeria. He formerly served as the Acting Director of Intellectual Property and Technology Transfer, Head of the Department of Microbiology, and Sub Dean of the Faculty of Science. Currently, he holds the positions of Chairman of the Grant Committee and Dean of the Faculty of Science at EDSU.
Prof. Adetunji is a Fellow of the Royal Society of Biology in the UK. Additionally, he serves as a Visiting Professor and the Executive Director of the Center for Biotechnology at Precious Cornerstone University, Nigeria. His research centers on applying biological techniques and microbial bioprocesses to achieve Sustainable Development Goals (SDGs) and contribute to advancements in agriculture.
Affiliations and expertise
Full Professor and Lecturer in the Microbiology Department at Faculty of Sciences, Edo State University Uzairue (EDSU), NigeriaOM
Olugbenga Samuel Michael
Olugbenga Samuel Michael, Ph.D, is a faculty at the Department of Physiology, Faculty of Basic Medical and Health Sciences, College of Health Sciences, Bowen University, Iwo, Osun State, Nigeria. His research interest over the years has focused on the cardiometabolic interactions that affect physiological processes in the body. His work on cardiovascular, renal and hepatic metabolic dysregulation in metabolic syndrome has made significant contribution to ongoing investigations to provide therapeutics for the management of metabolic syndrome. Microbiome research and its application in health and disease especially its involvement in the pathogenesis or management of cardiometabolic disorders, non-alcoholic fatty liver diseases, polycystic ovary syndrome has been one of his research interests. Furthermore, He explored the use and understanding of the mechanism of plant phytochemicals, nutraceuticals, pharmafoods and diets for the treatment of diseases. He has published several scientific journals and conference proceedings in local and international journals. He is a member of many scientific and professional bodies like Physiological Society, UK, European society of cardiologist, international society of hypertension, and Physiological Society of Nigeria
Affiliations and expertise
Department of Physiology, University of Tennessee Health Science Center, Memphis, TN, USA.NE
N. Esiobu
Nwadiuto (Diuto) Esiobu – (Ph.D., University of Louvain, Belgium; Post Doc. Massachusetts Institute of Technology, Cambridge USA) is currently a Professor of Microbiology and Biotechnology at Florida Atlantic University, Boca Raton, Fl. USA, where her microbial biotech laboratory integrates environmental genomics and health risk assessment with rapid pathogen detection using synthetic biology. Her research interests in agriculture and health include molecular ecology of plant invasion, soil fertility, and the applications of microbiomes in humans and plants. She has served in senior professional leadership roles in academia, industry and policy; including selection panel for the US President’s award for excellence in Math and Science (Washington DC) and more than 11 years on Committees of the Board of the American Society for Microbiology. A Fellow of the Biotechnology Society of Nigeria and a Jefferson Science Fellow, she was selected by the National Academy of Sciences as a senior science advisor to Secretary Clinton’s office of Global Food Security (GFS) and the Office of International Health and Biodefense (OES/IHB), US Department of State, Washington DC, and named world-class Faculty by the City of Fort Lauderdale for her contributions to the scientific enterprise
Affiliations and expertise
Professor of Microbiology and Biotechnology, Florida Atlantic Univeristy, Boca Raton, FL, USARA
Rotimi E. Aluko
Dr. Rotimi Aluko earned a PhD in Food Chemistry from the University of Guelph, Ontario, Canada and is currently a Professor of Human Nutritional Sciences at the University of Manitoba, Winnipeg, Canada. His research focus is on functional foods with an emphasis on food protein-derived bioactive peptides.
Affiliations and expertise
Professor and Tier 1 Canada Research Chair (Bioactive peptides), Department of Food and Human Nutritional Sciences, University of Manitoba, Winnipeg, CanadaRead An Introduction to the Microbiome in Health and Diseases on ScienceDirect