Regenerative Medicine in the Genitourinary System

1st Edition - April 19, 2024
Imprint: Academic Press
Editors: Farshid Sefat, Morvarid Saeinasab
Language: English
Paperback ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 8 3 4 - 6
eBook ISBN:
9 7 8 - 0 - 4 4 3 - 1 5 8 3 5 - 3

Regenerative Medicine in the Genitourinary System gives the reader a comprehensive overview of tissue engineering used to treat genitourinary disorders and infertility, also provid… Read more

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Regenerative Medicine in the Genitourinary System gives the reader a comprehensive overview of tissue engineering used to treat genitourinary disorders and infertility, also providing a great learning platform for researchers in different fields such as cell biology, pharmaceutics, clinicians, chemists, material scientists, and more. The book covers the latest innovations on the subject, but also acts as a resource for tissue engineering applications and regenerative medicine. Over the last several decades, tissue engineering has continued to make considerable advancements in therapeutic and clinical strategies that address male/female urological or genitourinary diseases.
Although several articles have been published on this topic, there are very few book chapters and no single book currently available dedicated to this topic.

Cover image
Title page
Table of Contents
Copyright
Contributors
Section 1. Introduction
Chapter 1. Genitourinary tissue engineering: Promises, advances, and challenges
1.1. Introduction
1.2. Regenerative medicine
1.3. Principles of tissue engineering
1.4. Genitourinary system anatomy and physiology
1.5. Genitourinary conditions
1.6. Current treatments and potential drawbacks
1.7. Genitourinary tissue engineering
1.8. Summary
Section 2. Urinary system
Chapter 2. The progress in tissue engineering of kidney
2.1. Introduction
2.2. Anatomy and physiology
2.3. History of kidney transplants and treatments
2.4. Tissue engineering of a kidney
2.5. Discussion and conclusion
Chapter 3. The progress in tissue engineering of bladder
3.1. Introduction
3.2. Bladder disease
3.3. Biomaterials for bladder regenerative medicine
3.4. Tissue engineering for bladder
3.5. Conclusion
Chapter 4. The progress in tissue engineering of urethra
4.1. Introduction
4.2. Etiology and anatomy
4.3. Tissue engineering of urethra
4.4. Clinical issues and discussion
Chapter 5. The progress in ureter tissue engineering
5.1. Introduction
5.2. Ureters anatomy
5.3. Physiology
5.4. Diseases of ureter
5.5. Ureter tissue engineering
5.6. Discussion and challenges
Section 3. Male reproductive system
Chapter 6. The progress in tissue engineering of penile corporal tissue
6.1. Introduction
6.2. Disease/disorders related to penile corporal tissue
6.3. Materials used for transplantation for penile corporal tissue
6.4. Physical bodies
6.5. Albuginea tunica
6.6. Latest and previous tissue engineering approaches for penile corporal tissue
6.7. Cell/stem cell used in penile corporal tissue
6.8. Conclusion
Chapter 7. The progress in tissue engineering of prostate
7.1. Introduction
7.2. Anatomy and histology of the prostate
7.3. Conditions of the prostate
7.4. Need for prostate tissue engineering
7.5. Tissue engineering approach
7.6. Conclusion
Chapter 8. The progress in tissue engineering of testicle
8.1. Introduction
8.2. Anatomy and physiology of the testes
8.3. Pathophysiology of the testicles
8.4. Biomaterials used for testicular tissue engineering
8.5. History of biomaterials used for testicular prostheses
8.6. Tissue engineering approach
8.7. Conclusion
Chapter 9. Tissue engineering applications for erectile dysfunction
9.1. Introduction
9.2. Anatomy and physiology of penis
9.3. Risk factors and diseases associated with ED
9.4. Current treatments
9.5. Biomaterials used for CC scaffolds
9.6. Desired properties of scaffolds
9.7. Cells used
9.8. Tissue engineering approach used
9.9. Engineered prosthesis
9.10. Engineered corpus cavernosum
9.11. Challenges
9.12. Conclusions
Chapter 10. Tissue engineering strategies to treat male infertility
10.1. Introduction
10.2. Male reproductive system physiology
10.3. Male infertility
10.4. Current treatments
10.5. Tissue engineering approaches for treating male infertility
10.6. Conclusion
Section 4. Female reproductive system
Chapter 11. The progress in tissue engineering of uterus
11.1. Introduction
11.2. Uterus anatomy and physiology
11.3. Uterus physiology
11.4. Common uterine diseases and disorders
11.5. Uterine histoarchitecture
11.6. UTx animal research
11.7. UTx human research
11.8. Tissue engineering
11.9. 2D models and 3D models
11.10. Cell source
11.11. Scaffolds
11.12. Natural and synthetic materials
11.13. Decellularized matrices
11.14. Uterine tissue engineering
11.15. Decellularization and recellularization strategy
11.16. Clinical research for tissue engineering of the uterus
11.17. Summary
Chapter 12. The progress in tissue engineering of vagina
12.1. Introduction
12.2. Vagina anatomy
12.3. Causes of vaginal disorders
12.4. Diagnosis of vagina disorder
12.5. Current treatment
12.6. Tissue engineering
12.7. Stem cells and vaginal reconstruction
12.8. Conclusions
Chapter 13. The progress in tissue engineering of cervix
13.1. Introduction
13.2. Conclusion
Chapter 14. The progress in tissue engineering of ovarian glands
14.1. Introduction
14.2. Anatomy and physiology of ovaries
14.3. Diseases related to ovaries
14.4. Tissue engineering of ovaries
14.5. Factors involved in tissue engineering
14.6. Recent trends in tissue engineering of ovaries
14.7. Conclusion
Chapter 15. The progress in tissue engineering of endometrium
15.1. Introduction
15.2. Endometrium anatomy and physiology
15.3. Regeneration of the endometrium: Challenges and opportunities
15.4. Biomaterials for tissue engineering
15.5. Bioengineering of endometrium
15.6. Summary
Chapter 16. Tissue engineering strategies to treat female infertility
16.1. Introduction
16.2. Female reproductive system
16.3. Cause of female infertility
16.4. Other risk factors of female infertility
16.5. Current treatments for female infertility
16.6. Tissue engineering-based approaches in treating female infertility
16.7. Conclusion
Index

Farshid Sefat

Dr. Farshid Sefat is Associate Professor and Programme Leader in the Biomedical and Electronic Engineering Department at the University of Bradford (UK). He was head of Biomedical Engineering Department at King Faisal University (Saudi Arabia) and Visiting Professor at Stevens Institute of Technology (New Jersey, USA). He completed his post doctorate research assistant at University of Sheffield (UK) in cornea tissue engineering. Dr. Sefat received his Ph.D. and BEng. degrees from University of Bradford in Biomedical Engineering. His research is based on developing biomaterials to control cellular behavior with particular emphasis in developing engineered materials for various tissue engineering applications. He’s an author of >150 peer-reviewed journal articles, editorials, and review papers and >80 book chapters/edited books. He’s on the editorial boards and reviewer of >30 numerous journals including Materials Today, Acta Biomaterialia, IEEE, Bone, MDPI, Journal of Orthopaedics & Rheumatology, Materials Science and Engineering C and Journal of Biomechanics.

Affiliations and expertise

Associate Professor, Biomedical and Electronic Engineering Department, University of Bradford, UK

Morvarid Saeinasab

Dr. Morvarid Saeinasab is Post Doctorate Research Associate in Cell and Molecular Biology at University of Manchester and Honorary Lecturer at the University of Bradford (UK). She completed her Ph.D. in 2019 focusing on investigation of the role of lncRNA in cancer. She also received her MSc. in Cell and Molecular Biology from Ferdowsi University of Mashhad focused on stem cell derivation and their differentiation into multiple cell lineage. Her research interest including application of different cell lines in regenerative medicine and tissue engineering focus on finding novel cell sources adapted for cell therapy. She is an author of >30 peer-reviewed journal articles, editorials, and review papers and >30 book chapters/edited book.

Affiliations and expertise

Research Associate, Faculty of Biology Medicine and Health, University of Manchester, Manchester, UK

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health