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Elsevier

Books in Life sciences

  • Stress: Physiology, Biochemistry, and Pathology

    Handbook of Stress Series, Volume 3
    • 1st Edition
    • George Fink
    • English
    Approx.406 pages

  • Neuroblastoma

    Molecular Mechanisms and Therapeutic Interventions
    • 1st Edition
    • Swapan K. Ray
    • English
    Neuroblastoma: Molecular Mechanisms and Therapeutic Interventions comprehensively reviews current concepts in molecular and histopathological mechanisms that influence the growth of human malignant neuroblastoma, along with exciting therapeutic interventions. This book features a broad collection of contributions from leading investigators in histopathology, molecular mechanisms, genetics, epigenetics, microRNAs, proteomics, and metabolism in controlling growth and death in neuroblastoma. Recent developments in therapeutic interventions for neuroblastoma are also covered extensively, including chapters on surgery, chemotherapy, targeted therapy and immunotherapy. This book is ideal for advanced undergraduate students, graduate students, medical students, postdoctoral fellows, and investigators with an interest in current molecular concepts and therapeutic interventions.

  • Nontuberculous Mycobacteria (NTM)

    Microbiological, Clinical and Geographical Distribution
    • 1st Edition
    • Ali Akbar Velayati + 1 more
    • English
    Nontuberculous Mycobacteria (NTM): Microbiological, Clinical and Geographical Distribution is a complete reference that stimulates a greater understanding of NTM infections. Sections cover microbiologic and molecular diagnostic tools, drug susceptibility tests, human genetic susceptibility, prevalence and incidence studies, clinical and radiological presentations, and clinical trials for antibiotic therapy. With the incidence rate of NTM infections increasing globally during the last decade, significant mortality and morbidity must be addressed. This important reference will provide research scientists, clinical microbiologists, hospital diagnostic technicians, and post graduate medical and science students with information on the epidemiology, prevalence, microbiology and clinical aspects of NTM.

  • Biological NMR Part B

    • 1st Edition
    • Volume 615
    • English
    Biological NMR, Part B, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs & micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery, Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration, Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, and much more.

  • Dietary Interventions in Liver Disease

    Foods, Nutrients, and Dietary Supplements
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Dietary Interventions in Liver Disease: Foods, Nutrients, and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the liver. It provides nutritional treatment options for those suffering from liver disease. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus illustrating that variations in intake can change antioxidant and disease preventing non-nutrients that affect liver health and/or disease promotion. This book is a valuable resource for biomedical researchers who focus on identifying the causes of liver diseases and food scientists targeting health-related product development.

  • Critical Issues in Alcohol and Drugs of Abuse Testing

    • 2nd Edition
    • Amitava Dasgupta
    • English
    Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more.

  • Dietary Interventions in Gastrointestinal Diseases

    Foods, Nutrients, and Dietary Supplements
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Dietary Interventions in Gastrointestinal Diseases: Foods, Nutrients and Dietary Supplements provides valuable insights into the agents that affect metabolism and other health-related conditions in the gastrointestinal system. It provides nutritional treatment options for those suffering from gastrointestinal diseases including Crohn’s Disease, Inflammatory Bowel Disease, Ulcerative Colitis and Allergies, among others. Information is presented on a variety of foods, including herbs, fruits, soy and olive oil, thus showing that changes in intake can change antioxidant and disease preventing non-nutrients and affect gastrointestinal health and/or disease promotion. This book serves as a valuable resource for biomedical researchers who focus on identifying the causes of gastrointestinal diseases and food scientists targeting health-related product development.

  • Innovations in Traditional Foods

    • 1st Edition
    • Charis M. Galanakis
    • English
    Innovations in Traditional Foods addresses the most relevant topics of traditional foods while placing emphasis on the introduction of innovations and consumer preferences. Certain food categories, such as fruits, grains, nuts, seeds, grains and legumes, vegetables, mushrooms, roots and tubers, table olives and olive oil, wine, fermented foods and beverages, fish, meat, milk and dairy products are addressed. Intended for food scientists, technologists, engineers and chemists working in food science, product developers, SMEs, researchers, academics and professionals, this book provides a reference supporting technological advances, product development improvements and potential positioning in the traditional food market.

  • Advances in Virus Research

    • 1st Edition
    • Volume 103
    • Thomas Mettenleiter + 2 more
    • English
    Advances in Virus Research, Volume 103, the latest in the Advances in Virus Research series, contains new, informative updates on the topic. First published in 1953, this series covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. Updates to this release include a Review on phage genes that affect bacterial phenotypes, Phage lysis: new perspectives on the bacterial cell envelope, CRISPRs as the adaptive immune system of archaea and bacteria, CRESS viruses, Tupanviruses, and Giant virus evolution, amongst other topics.

  • Biology of T Cells - Part B

    • 1st Edition
    • Volume 342
    • English
    Biology of T Cells - Part B, Volume 342, the latest release in the International Review of Cell and Molecular Biology series, offers an overview of the major molecular and cellular aspects of T-cell biology and their links to human pathophysiology. Chapters in this release include Metabolism of T lymphocytes in health and disease, T lymphocytes and autoimmunity, Cancer immunosurveillance by T cells, T lymphocytes as targets in viral disorders, Molecular mechanisms underlying pharmacological immunosuppression, T lymphocyte-based immunotherapeutics, In silico methods to analyze T cell biology, and Engineering Platforms for T Cell Modulation.

  • Molecular Chaperones in Human Disorders

    • 1st Edition
    • Volume 114
    • English
    Molecular Chaperones in Human Disorders, Volume 114 in the Advances in Protein Chemistry and Structural Biology series, provides an overview of current developments in mechanisms underlying DNA repair and their involvement in maintaining chromatin repair, the balance between chromosomal repair pathways, tumorigenesis, immune signaling and infection-induced inflammation. Chapters in this new release cover Functional principles and regulation of molecular chaperones, Chaperones and retinal disorders, Protein misfolding and degradation in genetic diseases, Chaperone dysfunction in hereditary myopathic diseases, Diseases caused by functional disorder of molecular chaperones residing in the endoplasmic reticulum, and many other timely topics.

  • Advances in Agronomy

    • 1st Edition
    • Volume 153
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 153, the latest release in this comprehensive series, continues its recognition as a leading, first-rate source for the latest research in agronomy. Each volume contains an eclectic group of reviews by leading scientists throughout the world. As always, the subjects covered are rich, varied, and exemplary of the abundant subject matter addressed by this long-running serial. Chapters in this updated volume include Novel Practice and Smart Technologies to Maximize the Nitrogen Fertilizer Value of Manure for Crop Production in Cold Humid Temperate Regions, Nitrogen Fertilization Management of Switchgrass, Miscanthus and Giant Reed: A Review, and much more.

  • Fundamentals of Radiation Oncology

    Physical, Biological, and Clinical Aspects
    • 3rd Edition
    • Hasan Murshed
    • English
    Fundamentals of Radiation Oncology: Physical, Biological, and Clinical Aspects, Third Edition continues to provide current, concise, and a readily available source of clinical information for busy practicing radiation oncologists. The book consists of 26 chapters, divided into four parts: Part I describes the basic science of radiation oncology, with discussions of radiation physics, radiation protection, and radiation biology, as well as molecular biology. Part II describes techniques and modalities of radiation oncology including brachytherapy, intensity-modulated radiation therapy (IMRT), stereotactic radiotherapy (SRS), stereotactic body radiation therapy (SBRT), and proton therapy. Significant recent advances made in the areas of immunotherapy and combined modality therapy; as such, these chapters have also been added to this new edition. Part III describes the clinical science of radiation oncology including risk factors, symptoms/signs, and investigations needed for the cancer diagnosis and up-to-date treatment recommendations in accordance with the new AJCC staging system. In addition, radiation treatment techniques, with an emphasis on IMRT, have been expanded to all the chapters. Also included in this version of the book is a chapter on benign diseases. Updated annotated bibliographies of latest landmark studies providing evidence-based rationale for the recommended treatments are presented at the end of each chapter. Part IV describes palliative radiation treatments to improve the quality of life for cancer patients and the management of side effects from radiation treatment. This book is a must-have for all radiation oncology residents, radiation oncologists and all professionals engaged in the care of cancer patients.

  • G Protein-Coupled Receptors, Part B

    • 2nd Edition
    • Volume 149
    • English
    G-Protein-Coupled Receptors, Part B, 2nd Edition, Volume 149, the latest release in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers Optical Approaches for Visualization of Arrestin Binding to Muscarinic Receptors, Luciferase Reporter Assay for Unlocking Ligand-mediated Signaling of GPCRs, Assays to Measure GPCR Dependent Cellular Migration, Characterization of the Frizzled GPCRs, Binding Assays for Bradykinin and Angiotensin Receptors, Detection of Misfolded Rhodopsin Aggregates in Cells, Measuring GPCR Ubiquitination and Trafficking, Culture of Primary Neurons and its Use in Studying GPCR Trafficking, and much more.

  • Plant Development and Evolution

    • 1st Edition
    • Volume 131
    • English
    Plant Development and Evolution, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on the Evolution of the plant body plan, Lateral root development and its role in evolutionary adaptation, the Development of the vascular system, the Development of the shoot apical meristem and phyllotaxis, the Evolution of leaf diversity, the Evolution of regulatory networks in land plants, The role of programed cell death in plant development, the Development and evolution of inflorescence architecture, the Molecular regulation of flower development, the Pre-meiotic another development, and much more.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 88
    • Gregory S. Makowski
    • English
    Advances in Clinical Chemistry, Volume 88, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Equine Behavioral Medicine

    • 1st Edition
    • Bonnie V. Beaver
    • English
    Equine Behavioral Medicine provides an essential resource for those who work with, study, and provide care to horses. It provides critical knowledge to help users understand the complex aspects of their behavior in order to benefit the animal, observe safe practices, and advance research in this area. The book includes current information on normal horse behavior and problem behaviors, particularly those associated with medical conditions, changes in the nervous system, and the use of drug therapy. Readers will gain a comprehensive understanding of the differences of the sensory systems and the concepts of learning that are helpful for successful treatments and safety. With the use of psychopharmacology becoming increasingly common by veterinarians, including for abnormal behaviors, is important to understand the rationale for the use of these medications. Understanding the intimate relationship between behavior, physiology, and health is key to practitioners, students, professionals, and others who work with, or care for, horses.

  • Microbiome and Metabolome in Diagnosis, Therapy, and other Strategic Applications

    • 1st Edition
    • Joel Faintuch + 1 more
    • English
    Microbiome and Metabolome in Diagnosis, Therapy, and Other Strategic Applications is the first book to simultaneously cover the microbiome and the metabolome in relevant clinical conditions. In a pioneering fashion, it addresses not only the classic intestinal environment, but also the oral, gastric, lung, skin and vaginal microbiome that is in line with the latest investigations. Nonbacterial microbiomes, such as fungi and viruses are not overlooked, and the plasma microbiome is also discussed. As plasma, brain, placenta, tumor cells, and other sterile fluids and tissues, are increasingly recognized to potentially host a microbiome, albeit a limited one, this is a timely resource. The book's editors were fortunate to have the input of renowned collaborators from nearly all continents. This is truly an international effort that brings the latest in the field to students and professionals alike.

  • The Orexin/Hypocretin System

    Functional Roles and Therapeutic Potential
    • 1st Edition
    • Jim R. Fadel + 1 more
    • English
    The Orexins/Hypocretins System: Functional Roles and Therapeutic Potential summarizes research on both the physiological functioning of orexins, their impact on homeostatic processes, and related disorders. The book encompasses the effects on appetite, sleep, substance abuse, cognition, and anxiety. Additionally, it examines new therapeutic approaches utilizing orexins, including utilization of orexin receptors for drug development. It is essential reading for neuroscience researchers interested in brain-behavior relationships, as well as psychiatrists, endocrinologists and pharmacologists.

  • Biological NMR Part A

    • 1st Edition
    • Volume 614
    • A.Joshua Wand
    • English
    Biological NMR, Part A, the latest release in the Methods of Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Protein methyl labeling, Membrane protein expression – yeast, Protein aromatic labeling, His-tag/Metal contamination, Bicelles, nanodiscs and micelles MP host, PTM – phosphorylation, PTM – lipidation, Screening platform for receptor-ligand discovery Solution Spectroscopy, Large protein strategies, NUS data collection/analysis, F19 incl. hydration, ODNP - hydration, Reverse micelle - Hydration Solid State Spectroscopy, SS NMR membrane proteins, SS NMR soluble/aggregate proteins, SS DNP - general, SS NMR nucleic acids, Structure determination and computer analysis, and much more.

  • The Auditory Brain and Age-Related Hearing Impairment

    • 1st Edition
    • Jos J. Eggermont
    • English
    The Auditory Brain and Age-Related Hearing Impairment provides an overview of the interaction between age-related hearing impairments and cognitive brain function. This monograph elucidates the techniques used in the connectome and other brain-network studies based on electrophysiological methods. Discussions of the manifestations of age-related hearing impairment, the causes of degradation of sound processing, compensatory changes in the human brain, and rehabilitation and intervention are included. There is currently a surge in content on aging and hearing loss, the benefits of hearing aids and implants, and the correlation between hearing loss, cognitive decline and early onset of dementia. Given the changing demographics, treatment of age-related hearing impairment need not just be bottom-up (i.e., by amplification and/or cochlear implantation), but also top-down by addressing the impact of the changing brain on communication. The role of age-related capacity for audio-visual integration and its role in assisting treatment have only recently been investigated, thus this area needs more attention.

  • Neurobiology of Depression

    Road to Novel Therapeutics
    • 1st Edition
    • João L. de Quevedo + 2 more
    • English
    Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness.

  • Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain

    • 1st Edition
    • Michael Petrides
    • English
    Atlas of the Morphology of the Human Cerebral Cortex on the Average MNI Brain provides a comprehensive identification of the sulci and gyri of the human brain on a series of coronal sections of the average MNI brain and identifies the likely location of the cytoarchitectonic areas of the cerebral cortex. Presentation in MNI Stereotaxic Space enables the atlas to serve as a useful working tool for structural/functiona... neuroimagers attempting to identify the sulcus or gyrus and the likely cytoarchitectonic area within which a functional activation or a structural change has occurred. A brief introductory section discusses the history and current state of studies of the sulcal and gyral morphology and cytoarchitecture of the human cerebral cortex.

  • Processing and Sustainability of Beverages

    Volume 2: The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Processing and Sustainability of Beverages, Volume Two in the Science of Beverages series, is a general reference of the current and future actions for a sustainable beverage industry. This resource takes a unique approach, combining processing with sustainability. Topics of note include waste treatment and management, environmental analysis for a sustainable beverage industry, and modern technologies for beverage processing to reduce contaminants and increase the quality. This book is essential to scientists, researchers and technologists in the beverages field, covering both alcoholic and nonalcoholic beverages.

  • Production and Management of Beverages

    Volume 1. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Production and Management of Beverages, Volume One in the Science of Beverages series, introduces the broad world of beverage science, providing an overview of the emerging trends in the industry and the potential solutions to challenges such as sustainability and waste. Fundamental information on production and processing technologies, safety, quality control, and nutrition are covered for a wide range of beverage types, including both alcoholic and nonalcoholic beverages, fermented beverages, cocoa and other powder based beverages and more. This is an essential resource for food scientists, technologists, chemists, engineers, microbiologists and students entering into this field.

  • The Eradication of Dracunculiasis (Guinea Worm Disease) in Nigeria

    An Eyewitness Account
    • 1st Edition
    • Luke Ekundayo Edungbola
    • English
    The Eradication of Dracunculiasis (Guinea Worm Disease) in Nigeria: An Eyewitness Account documents the process used to eradicate one of the most neglected public health challenges in Nigeria. The book's chapters discuss the need for well developed and implemented eradication strategies, the availability of human and material resources, and the collaboration that is necessary with international partners. In addition, sections highlight challenges, the benefits of perseverance, and the international support and multi-sectoral approach that is needed to tackle national problems. It demonstrates that other endemic tropical diseases and conditions can be eliminated or controlled if a similar approach is adopted.

  • Bioactive Compounds

    Health Benefits and Potential Applications
    • 1st Edition
    • Maira Rubi Segura Campos
    • English
    Bioactive Compounds: Health Benefits and Potential Applications provides information about different bioactive compounds including their sources, biological effects, health benefits and, potential applications which could contribute as alternatives in the prevention or treatment of multifactorial diseases for vulnerable population groups. Going beyond the basics to include discussion of bioaccessibility and the legislative aspects of marketing of bioactive compounds as nutraceuticals or food supplements, this book presents insights from a global perspective. Written for researchers, professors and graduate students, this book is sure to be a welcomed reference for all who work in food chemistry, new product development and nutritional science.

  • Imagining the Brain: Episodes in the History of Brain Research

    • 1st Edition
    • Volume 243
    • Chiara Ambrosio + 1 more
    • English
    Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Machine Learning in Bio-Signal Analysis and Diagnostic Imaging

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Machine Learning in Bio-Signal Analysis and Diagnostic Imaging presents original research on the advanced analysis and classification techniques of biomedical signals and images that cover both supervised and unsupervised machine learning models, standards, algorithms, and their applications, along with the difficulties and challenges faced by healthcare professionals in analyzing biomedical signals and diagnostic images. These intelligent recommender systems are designed based on machine learning, soft computing, computer vision, artificial intelligence and data mining techniques. Classification and clustering techniques, such as PCA, SVM, techniques, Naive Bayes, Neural Network, Decision trees, and Association Rule Mining are among the approaches presented. The design of high accuracy decision support systems assists and eases the job of healthcare practitioners and suits a variety of applications. Integrating Machine Learning (ML) technology with human visual psychometrics helps to meet the demands of radiologists in improving the efficiency and quality of diagnosis in dealing with unique and complex diseases in real time by reducing human errors and allowing fast and rigorous analysis. The book's target audience includes professors and students in biomedical engineering and medical schools, researchers and engineers.

  • The Chick Brain in Stereotaxic Coordinates and Alternate Stains

    Featuring Neuromeric Divisions and Mammalian Homologies
    • 2nd Edition
    • Luis Puelles + 4 more
    • English
    This atlas – and its accompanying text - is the most comprehensive work on avian neuroanatomy available so far. It identifies more than 900 hundred structures (versus ca. 250 in previous avian atlases), 180 of them for the first time. It correlates avian and mammalian neuroanatomy on the basis of homologies and applies mammalian terms to homologous avian structures. This is the first atlas that represents the fundamental histogenetic domains of the vertebrate neuroaxis on the basis of sound fate-mapping and gene expression data. This results in a substantial increase in accuracy of delineations. Developmental molecular biologists will find it easier to extrapolate early neural tube patterns into mature structures. The modern trend to shift avian neuroanatomical nomenclature toward mammalian terminology by reference to postulated homologies has been expanded to the entire brain, but is not yet complete. This creates a new standard for comparative cross-reference, which can also be applied to reptilian-mammalian comparisons.

  • Enzymes of Energy Technology

    • 1st Edition
    • Volume 613
    • Fraser Armstrong
    • English
    Enzymes of Energy Technology, Volume 613 in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Chapters include Purification of fully active and crystallizable photosystem II from thermophilic cyanobacteria, Production and manipulation of [NiFeSe]-hydrogenase... for renewable hydrogen research, Hydrogen production by [FeFe]-hydrogenases, Production and properties of enzymes that activate and produce carbon monoxide, Recombinant [NiFe]-hydrogenases from E. coli, Working with nitrogenase, Oxygen--tolerant [NiFe]-hydrogenases, Cytoplasmic and Membrane Bound Hydrogenases from the hyperthermophile Pyrococcus furiosus, and more. Additional sections cover Enzymatic conversion of methane into useful chemicals, Production and investigations of trans-membrane electron transfer protein, Characterization of post-translational modifications in methyl-coenzyme M reductase in diverse methanogens by mass-spectrometry, Reductive activation of carbon dioxide by formate dehydrogenases, and Lytic polysaccharide monooxygenases in biofuel processing. 14. Production and manipulation of blue copper oxidases for technological applications Yasmina Mekmouche

  • Cyanobacteria

    From Basic Science to Applications
    • 1st Edition
    • A.K. Mishra + 2 more
    • English
    Cyanobacteria constitute the most widely distributed group of photosynthetic prokaryotes found in almost all realms of the earth and play an important role in Earth’s nitrogen and carbon cycle. The gradual transformation from reducing atmosphere to oxidizing atmosphere was a turning point in the evolutionary history of the earth and made conditions for present life forms possible. Cyanobacteria: From Basic Science to Applications is the first reference volume that comprehensively discusses all aspects of cyanobacteria, including the diverse mechanisms of cyanobacteria for the advancement of cyanobacterial abilities, towards higher biofuel productivity, enhanced tolerance to environmental stress and bioactive compounds and potential for biofertilizers.

  • Basic Fundamentals of Drug Delivery

    • 1st Edition
    • English
    Basic Fundamentals of Drug Delivery covers the fundamental principles, advanced methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to transform a drug candidate or new chemical entity into a final administrable drug delivery system. The book also covers various approaches involved in optimizing the therapeutic performance of a biomolecule while designing its appropriate advanced formulation.

  • Sustainable Food and Agriculture

    An Integrated Approach
    • 1st Edition
    • Clayton Campanhola + 1 more
    • English
    Sustainable Food and Agriculture: An Integrated Approach is the first book to look at the imminent threats to sustainable food security through a cross-sectoral lens. As the world faces food supply challenges posed by the declining growth rate of agricultural productivity, accelerated deterioration of quantity and quality of natural resources that underpin agricultural production, climate change, and hunger, poverty and malnutrition, a multi-faced understanding is key to identifying practical solutions. This book gives stakeholders a common vision, concept and methods that are based on proven and widely agreed strategies for continuous improvement in sustainability at different scales. While information on policies and technologies that would enhance productivity and sustainability of individual agricultural sectors is available to some extent, literature is practically devoid of information and experiences for countries and communities considering a comprehensive approach (cross-sectoral policies, strategies and technologies) to SFA. This book is the first effort to fill this gap, providing information on proven options for enhancing productivity, profitability, equity and environmental sustainability of individual sectors and, in addition, how to identify opportunities and actions for exploiting cross-sectoral synergies.

  • Biocontamination Control for Pharmaceuticals and Healthcare

    • 1st Edition
    • Tim Sandle
    • English
    Biocontamination Control for Pharmaceuticals and Healthcare outlines a biocontamination strategy that tracks bio-burden control and reduction at each transition in classified areas of a facility. This key part of controlling risk escalation can lead to the contamination of medicinal products, hence necessary tracking precautions are essential. Regulatory authorities have challenged pharmaceutical companies, healthcare providers, and those in manufacturing practice to adopt a holistic approach to contamination control. New technologies are needed to introduce barriers between personnel and the environment, and to provide a rapid and more accurate assessment of risk. This book offers guidance on building a complete biocontamination strategy.

  • The Technology of Wafers and Waffles II

    Recipes, Product Development and Know-How
    • 1st Edition
    • Karl F. Tiefenbacher
    • English
    The Technology of Wafers and Waffles: Recipes, Product Development and Knowhow is the definitive reference book addressing new product development in wafers and waffles. As a companion manual to The Technology of Wafers and Waffles: Operational Aspects, it provides a varied selection of recipes for different types of wafers, waffles, and fillings. This book discusses flat and shaped wafers, ice cream cones, cups, wafer reels, wafer sticks, stroop waffles, and North American frozen waffles. A separate chapter focuses on recipe calculations for wafer and waffle batters, doughs, and fillings, which allows estimating output, cost, and main nutrient content. Finally, there is also an overview on the patent and food science literature on wafers and waffles in chronological order.

  • Dog Behavior

    Modern Science and Our Canine Companions
    • 1st Edition
    • James C. Ha + 1 more
    • English
    Dog Behavior: Modern Science and Our Canine Companions provides readers with a better understanding of canine science, including evolutionary concepts, ethograms, brain structures and development, sensory perspectives, the science of emotions, social structure, and the natural history of the species. The book also analyzes relationships between humans and dogs and how the latter has evolved. Readers will find this to be an ideal resource for researchers and students in animal behavior, specifically focusing on dog behavior and human-canine relationships. In addition, veterinarians seeking further information on dog behavior and the social temperament of these companion animals will find this book to be informative.

  • Breath Analysis

    • 1st Edition
    • Giorgio Pennazza + 1 more
    • English
    Breath Analysis presents state-of-the-art research in this specialized field, also offering guidance on how best to design the technology and conduct analysis. The book primarily focuses on the diagnosis of lung cancer, asthma and Chronic Obstructive Pulmonary Diseases. The reliability, consistency and utility of the results from breath analysis depends on exhaled breath sampling procedures and tools, gas sensor array technology (sensing material and transducer), and finally, medical pertinence and interpretation. The book gives step-by-step procedures and discusses best practice solutions for problems in sample collection, sensor technology, clinical assessment, medical interpretation and data analysis. The book's primary audience would include biomedical engineers and medical doctors, but it is also useful for hospital technicians, hospital and biomedical SME leading figures, and those in PhD level Engineering and Medicine.

  • Senescence Signalling and Control in Plants

    • 1st Edition
    • Maryam Sarwat + 1 more
    • English
    Senescence Signalling and Control in Plants discusses the studies showing the importance of hormone action on developmental senescence. It shows the involvement of various signaling components (such as EIN2, LOX2) and transcription factors (such as oresara1 or ORE1) in controlling hormonal activity during senescence. Further, the involvement of various micro RNAs (miR164, miR319) in regulating leaf senescence are discussed. Through this book, the authors throw light on all the reverse and forward genetic approaches to reveal the role of various other phytohormones regulating plant senescence and the molecular mechanisms involved. Chapters on relevant topics are contributed by experts working in the area, making this a comprehensive treatise designed to provide an in-depth analysis on the subject matter.

  • Handbook of Biomechatronics

    • 1st Edition
    • Jacob Segil
    • English
    Handbook of Biomechatronics provides an introduction to biomechatronic design as well as in-depth explanations of some of the most exciting and ground-breaking biomechatronic devices in the world today. Edited by Dr. Jacob Segil and written by a team of biomechatronics experts, the work begins with broad topics concerning biomechatronic design and components, followed by more detailed discussions of specific biomechatronic devices spanning many disciplines. This book is structured into three main parts: biomechatronic design, biomechatronic components, and biomechatronic devices. The biomechatronic design chapter discusses the history of biomechatronics, conceptual design theory, biomechatronic design methods, and design tools. The next section discusses the technologies involved in the following components: sensors, actuators, and control systems. The biomechatronic devices chapters contains distinct examples of biomechatronic devices spanning visual prostheses to brain-machine interfaces. Each chapter presents the development of these biomechatronic devices followed by an in-depth discussion of the current state of the art

  • High-Density Sequencing Applications in Microbial Molecular Genetics

    • 1st Edition
    • Volume 612
    • English
    High-Density Sequencing Applications in Microbial Molecular Genetics, Volume 612 in the Methods of Enzymology series provides the latest on the high-density sequencing of DNA and cDNA libraries and how they have revolutionized contemporary research in biology. Methods permitting tens of millions of sequence reads in a single experiment have paved the way to genome-wide studies that are contributing to our understanding of the complexity of living systems. Chapters in this updated volume include Characterizing the role of exoribonucleases in the control of microbial gene expression: Differential RNA seq., Conformational studies of bacterial chromosomes by high-throughput sequencing methods, Measuring mRNA degradation, and more. Addition sections cover Global recognition patterns of bacterial RNA-binding proteins, High-resolution profiling of NMD targets, and the Generation of a metagenomic 3C/Hi-C library of human gut microbiota, Genome-wide mapping of yeast retrotransposons integration target sites, Measuring protein synthesis rates, Finding unsuspected partners of small RNAs with new screening approaches, Use of multiplexed transcriptomics to define the relationship between promoter sequence and transcription output, RNA-based control of quorum sensing in Vibrio cholerae, amongst other highly regarded topics.

  • Cadmium Toxicity and Tolerance in Plants

    From Physiology to Remediation
    • 1st Edition
    • Mirza Hasanuzzaman + 2 more
    • English
    Cadmium Toxicity and Tolerance in Plants: From Physiology to Remediation presents a single research resource on the latest in cadmium toxicity and tolerance in plants. The book covers many important areas, including means of Cd reduction, from plant adaptation, including antioxidant defense, active excretion and chelation, to phytoextraction, rhizo filtration, phytodegradation, and much more. In addition, it explores important insights into the physiological and molecular mechanisms of Cd uptake and transport and presents options for improving resistance to Cd stresses. It will be ideal for both researchers and students working on cadmium pollution, plant responses and related fields of environmental contamination and toxicology.

  • Laboratory Assessment of Vitamin Status

    • 1st Edition
    • Dominic J. Harrington
    • English
    Laboratory Assessment of Vitamin Status provides a comprehensive understanding of the limitations of commonly used approaches used for the evaluation of vitamin status, reducing harm in the general health setting. It outlines the application of ‘Best Practice’ approaches to the evaluation of vitamin status, giving physicians and other healthcare professionals the opportunity to make evidence-based interventions. Nearly every metabolic and developmental pathway in the human body has a dependency on at least one micronutrient. Currently, the clinical utility of approaches taken by laboratories for the assessment of vitamin status is generally poorly understood, missing the opportunity to diagnosis vitamin deficiencies. This essential reference gives clinical and biomedical scientists an understanding of the limitations of commonly used approaches to the evaluation of vitamin status in the general health setting through change in practice. Nutritionists and dietitians gain an understanding of more sophisticated markers of vitamin status.

  • Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders

    • 1st Edition
    • Lindsay M. Oberman + 1 more
    • English
    Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback.

  • Case Studies in the Wine Industry

    • 1st Edition
    • Cristina Santini + 1 more
    • English
    Case Studies in the Wine Industry aims to close the gap between academic researchers and industry professionals through real world scenarios and field-based research. The book explores how consumer and sensory science has been implemented in the wine industry to achieve certain goals, including the rejuvenation of product image, the shaping of new market places, the achievement of market differentiation and geographical diffusion, the achievement of customer loyalty, and the promotion of traditional features of the product. There is an emerging demand from wine industry professionals and undergraduate and postgraduate students who attend business and agricultural studies courses who want to gain practical information through real cases and field-based research.

  • Epigenetics of Cancer Prevention

    • 1st Edition
    • Volume 8
    • Anupam Bishayee + 1 more
    • English
    Epigenetics of Cancer Prevention, Volume Ten is the first to look at epigenetics and chemoprevention together. Although there is numerous scientific data available on how epigenetics can lead to cancer and how chemoprevention can be beneficial in the treatment of, or improvement of quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin and resveratrol, and organ specific epigenetic targets related to diverse types of cancer, for example prostate, colorectal, breast, lung and skin cancers. Additionally, it encompasses a discussion on research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs and personalized cancer treatment with phytochemicals. The book is ideal for cancer researchers, health care professionals and all individuals who are interested in cancer prevention research and its clinical applications, especially in natural remedies.

  • Pharmacogenomics

    Challenges and Opportunities in Therapeutic Implementation
    • 2nd Edition
    • Yui-Wing Francis Lam + 1 more
    • English
    Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations.With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation.

  • The Human Challenge of Telemedicine

    Toward Time-sensitive and Person-centered Ethics in Home Telecare
    • 1st Edition
    • Philippe Bardy
    • English
    Telepatients using connected objects to collect time-sensitive data about their health are not neutral carriers of diagnosable symptoms. Patients are persons, or personal beings as well as co-carers, whose personal experience, history and know-how must be acknowledged in time-sensitive telecare practices. Such practices require a relational ethics, inspired by medical ethics and an ethics of virtues, focusing on vulnerability and emotional health, to oversee telecare good practices, define a new therapeutic alliance compliant with patients’ values, and reconcile the technical and human sides of telemedicine.

  • Nutrition in the Prevention and Treatment of Abdominal Obesity

    • 2nd Edition
    • Ronald Ross Watson
    • English
    Nutrition in the Prevention and Treatment of Abdominal Obesity, Second Edition focuses on the important role that exercise, dietary changes and foods play in promoting and reducing visceral fat. Nutritionists, dieticians and healthcare providers seeking to address the abdominal obesity epidemic will find this book to be a valuable resource in their long-term goal of preventing chronic diseases, especially heart, vascular and diabetic diseases. Chapters define a range of dietary approaches to reduce risk for the associated chronic diseases. In addition, discussions of the importance of dietary approaches to reduce abdominal obesity, along with clinical approaches, are discussed, including costs and risks.

  • Neurosensory Disorders in Mild Traumatic Brain Injury

    • 1st Edition
    • Michael E. Hoffer + 1 more
    • English
    Mild traumatic Brain Injury (mTBI or Concussion) is an increasingly common public health issue in sports, military environments, and life in today’s active world. Despite a great deal of study and public attention to this disorder, knowledge about optimal diagnostic, prognostic, and treatment information remains lacking. Neurosensory symptoms have been shown to be the most frequent complications of mTBI in both the acute and chronic setting. Neurosensory Disorders in Mild Traumatic Brain Injury brings together both the basic science work as well as the clinical work in mTBI into one volume to provide a comprehensive examination of the neurosensory issues associated with this disorder. Coverage includes chapters on defining mild Traumatic Brain Injury, neurosensory consequences, neurosensory disorders in clinical practice, and diagnosis and treatment for neurosensory disorders in mTBI. This book is written for clinicians, researchers, residents and students in neurology and neuroscience.

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