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Elsevier

Books in Life sciences

  • Virus as Populations

    Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
    • 2nd Edition
    • Esteban Domingo
    • English
    Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere.

  • Principles of Tumors

    A Translational Approach to Foundations
    • 2nd Edition
    • Leon P. Bignold
    • English
    Principles of Tumors: A Translational Approach to Foundations, Second Edition, provides a concise summary of translational/interd... topics on the various aspects of tumors, especially abnormalities in their cells, their causes and effects on patients. Topics discussed include how genomic abnormalities in tumors may result from the actions of carcinogens and how genomic changes determine the cell biological/morpholog... abnormalities in tumor cell populations. In addition, the relationships between tumor cell genomics and therapeutic outcomes are described. There are also supporting appendices on general bioscience, including the principles of histology (the cells and tissues of the body), genetics, pathology, radiology and pharmacology. This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine.

  • The Interaction of Food Industry and Environment

    • 1st Edition
    • Charis M. Galanakis
    • English
    The Interaction of Food Industry and Environment addresses all levels of interaction, paying particular attention to avenues for responsible operational excellence in food production and processing. Written at a scientific level, this book explores many topics relating to the food industry and environment, including environmental management systems, environmental performance evaluation, the correlation between food industry, sustainable diets and environment, environmental regulation on the profitability of sustainable water use in the food industry, lifecycle assessment, green supply chain network design and sustainability, the valorization of food processing waste via biorefineries, food-energy-environm... trilemma, wastewater treatment, and much more. Readers will also find valuable information on energy production from food processing waste, packaging and food sustainability, the concept of virtual water in the food industry, water reconditioning and reuse in the food industry, and control of odors in the food industry. This book is a welcomed resource for food scientists and technologists, environmentalists, food and environmental engineers and academics.

  • Encyclopedia of Gastroenterology

    • 2nd Edition
    • Ernst J. Kuipers
    • English
    Encyclopedia of Gastroenterology, Second Edition, Four Volume Set provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included.

  • Prognostic Epigenetics

    • 1st Edition
    • Volume 15
    • English
    This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases. Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook.

  • Stress Resilience

    Molecular and Behavioral Aspects
    • 1st Edition
    • Alon Chen
    • English
    Stress Resilience: Molecular and Behavioral Aspects presents the first reference available on the full-breadth of cutting-edge research being carried out in this field. It includes a wide range of basic molecular knowledge on the potential associations between resilience phenomenon and biochemical balance, but also focuses on the molecular and cellular mechanisms underlying stress resilience. World-renowned experts provide chapters that cover everything from the neural circuits of resilience, the effects of early-life adversity, and the transgenerational inheritance of resilience. This unique and timely book will be a go-to resource for neuroscientists and biological psychiatrists who want to improve their understanding of the consequences of stress and on how some people are able to avoid it.

  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 109
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 109, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic.

  • Enzyme Activity in Single Cells

    • 1st Edition
    • Volume 628
    • English
    Enzyme Activity in Single Cells, Volume 628, the latest release in the Methods of Enzymology series, discusses groundbreaking cellular physiology research that is taking place in the biological sciences. Chapters in this new release cover Spatial and temporal resolution of caspase waves in single Xenopus eggs during apoptosis, Spatial and temporal organization of metabolic complexes in cells, Measuring cellular efflux and biomolecular delivery: synthetic approaches to imaging and engineering cells, Slide-based, single-cell enzyme assays, Single-cell assays using integrated continuous-flow microfluidics, High-throughput screening of single-cell lysates, Microfluidic capture of single cells for drug resistance assays, and much more.

  • Fundamentals of Telemedicine and Telehealth

    • 1st Edition
    • Shashi Gogia
    • English
    Fundamentals of Telemedicine and Telehealth provides an overview on the use of information and communication technologies (ICTs) to solve health problems, especially for people living in remote and underserviced areas. With the advent of new technologies and improvement of internet connectivity, telehealth has become a new subject requiring a new understanding of IT devices and how to utilize them to fulfill health needs. The book discusses topics such as digitizing patient information, technology requirements, existing resources, planning for telehealth projects, and primary care and specialized applications. Additionally, it discusses the use of telemedicine for patient empowerment and telecare in remote locations. Authored by IMIA Telehealth working group, this book is a valuable source for graduate students, healthcare workers, researchers and clinicians interested in using telehealth as part of their practice or research.

  • Medical Device Design

    Innovation from Concept to Market
    • 2nd Edition
    • Peter J. Ogrodnik
    • English
    Medical Device Design: Innovation from Concept to Market, Second Edition provides the bridge between engineering design and medical device development. There is no single text that addresses the plethora of design issues a medical devices designer meets when developing new products or improving older ones; this book fills that need. It addresses medical devices' regulatory (FDA and EU) requirements, shows the essential methodologies medical designers must understand to ensure their products meet requirements, and brings together proven design protocols, thus enabling engineers and medical device manufacturers to rapidly bring new products to the marketplace. This book is unique because it takes the reader through the process of medical device development, from very early stages of conceptualization, to commercialization on the global market. This rare resource can be used by both professionals and newcomers to device design.

  • Animal Agriculture

    Sustainability, Challenges and Innovations
    • 1st Edition
    • Fuller W. Bazer + 2 more
    • English
    Animal Agriculture: Sustainability, Challenges and Innovations discusses the land-based production of high-quality protein by livestock and poultry and how it plays an important role in improving human nutrition, growth and health. With exponential growth of the global population and marked rises in meat consumption per capita, demands for animal-source protein are expected to increase 72% between 2013 and 2050. This raises concerns about the sustainability and environmental impacts of animal agriculture. An attractive solution to meeting increasing needs for animal products and mitigating undesirable effects of agricultural practices is to enhance the efficiency of animal growth, reproduction, and lactation. Currently, there is no resource that offers specific knowledge of both animal science and technology, including biotechnology for the sustainability of animal agriculture for the expanding global demand of food in the face of diminishing resources. This book fills that gap, giving readers all the necessary information on important issues facing modern animal agriculture, namely its sustainability, challenges and innovative solutions.

  • Medicinal Chemistry Approaches to Malaria and Other Tropical Diseases

    • 1st Edition
    • Volume 53
    • English
    Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Loomis's Essentials of Toxicology

    • 5th Edition
    • A. Wallace Hayes + 3 more
    • English
    Loomis's Essentials of Toxicology, Fifth Edition, provides the information on the harmful biologic effects associated with exposures to chemicals of all types. The scope of this book includes a discussion of the major types of chemicals involved, their general properties and detrimental biologic effects, the methods used to demonstrate these effects, the basis for clinical diagnosis, and therapy for the harmful effects of chemicals on humans. Individual examples are used to demonstrate the principle discussed. This reference volume will be an invaluable resource for both toxicologists and graduate and advanced undergraduate students in toxicology and public health.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 93
    • English
    Advances in Clinical Chemistry, Volume 93, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. New chapters in this release include Lectin biosensors in cancer glycan biomarker detection, Cytokines in heart failure, Recent advances in the determination of insulins from biological fluids, Biomarkers in aggression, Evaluation of analytical performance of immunoassay methods for cTnI and cTnT: From theory to practice, Periodontal disease: From the lenses of light microscopy to the specs of proteomics and next generation sequencing, and more.

  • Proteomic and Metabolomic Approaches to Biomarker Discovery

    • 2nd Edition
    • Haleem J. Issaq + 1 more
    • English
    Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research.

  • Nanoencapsulation of Food Ingredients by Specialized Equipment

    Volume 3 in the Nanoencapsulation in the Food Industry series
    • 1st Edition
    • Volume 3
    • English
    Nanoencapsulation of Food Ingredients by Specialized Equipment, Third Edition, a new volume in the Nanoencapsulation in the Food Industry series provides an overview of specialized developed equipment for the nanoencapsulation of food ingredients. Electro-spinning, electro-spraying, nano-spray dryer, micro/nano-fluidics systems and sonication devices are just some of the equipment analyzed in the book. Each chapter reviews the mechanisms of innovative devices for preparation of nanostructures, exploring the key factors in each device to control the efficiency of nanoencapsulation and revealing the morphologies and properties of nanoencapsulated ingredients produced by each equipment. Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical, and pharmaceutical ingredients, this title is of great value to those engaged in the various fields of of nanoencapsulation.

  • Natural Remedies for Pest, Disease and Weed Control

    • 1st Edition
    • Chukwuebuka Egbuna + 1 more
    • English
    Natural Remedies for Pest, Disease and Weed Control presents alternative solutions in the form of eco-friendly, natural remedies. Written by senior researchers and professionals with many years of experience from diverse fields in biopesticides, the book presents scientific information on novel plant families with pesticidal properties and their formulations. It also covers chapters on microbial pest control and control of weeds by allelopathic compounds. This book will be invaluable to plant pathologists, agrochemists, plant biochemists, botanists, environmental chemists and farmers, as well as undergraduate and postgraduate students.

  • Hormonal Signaling in Biology and Medicine

    Comprehensive Modern Endocrinology
    • 1st Edition
    • Gerald Litwack
    • English
    Hormonal Signaling in Biology and Medicine: Comprehensive Modern Endocrinology covers the endocrine secretions produced by every organ. This extensive collection of knowledge is organized by tissue, addressing how certain hormones are synthesized in multiple tissues, along with their structure, function and pathways, which are very applicable for researchers in drug design who need to focus on a specific step along the pathway. This is a must have reference for researchers in endocrinology and practicing endocrinologists, but it is also ideal for biochemists, pharmacologists, biologists and students.

  • Lymphatic Structure and Function in Health and Disease

    • 1st Edition
    • Felicity N.E. Gavins + 1 more
    • English
    Lymphatic Structure and Function in Health and Disease serves as a resource book on what has been learned about lymphatic structure, function and anatomy within different organ systems. This is the first book to bring together lymphatic medicine as a whole, with in-depth analysis of specific aspects of lymphatics in different vascular pathologies. This book is a useful tool for scientists, practicing clinicians and residents, in particular, those in vascular biology, neurology, cardiology and general medicine. Chapters discuss topics such as ontogeny and phylogeny of lymphatics, lymphatic pumping, CNS lymphatics, lymphatics in transplant and lymphatic reconstruction.

  • Implementing Biomedical Innovations into Health, Education, and Practice

    Preparing Tomorrow's Physicians
    • 1st Edition
    • James O. Woolliscroft
    • English
    Our increased understanding of health and disease coupled with major technologic advances has resulted in rapid and significant changes in the practice of medicine. How we prepare physicians for clinical practice 20, 30, or 40 years from now is of paramount importance to medical educators, to the future professionals, and to society at large. Implementing Biomedical Innovations into Health, Education, and Practice delves into this important question, discussing the effects of precision medicine, bioinformatics, biologic and environmental forces, and societal shifts on the physician’s approach to diagnosis and therapy. The author interviewed world-renowned physicians, medical educators, healthcare leaders, and research professionals—their insights and quotes are woven throughout the narrative. Professionally illustrated, this relevant resource is a must-have for all medical professionals who incorporate technology and biomedical innovations in their research and clinical practice. It encourages thoughtful analysis on adapting and developing the foundational knowledge, skills, and aptitudes of future physicians and other healthcare professionals, and it belongs in your library. “Having completed deanship at one of America’s leading medical schools, Jim Woolliscroft produces an insightful, contemplative projection of the likely skill and behavioral needs of the physician workforce for the mid-21st century...The result is a playbook for physician training that responds effectively to the daunting challenges faced in the coming transformation of the role of physicians in protecting the health of our nation.”James L. Madara, MD, CEO, American Medical Association “Dr. Woolliscroft’s provocative new book will become must reading for all who are serious about educating the next generation of physicians and health care leaders. Leveraging his own experience as a consummate educator and interviews with numerous thought leaders, he identifies the uncertainties, challenges and disruptions to the practice of medicine in the decades ahead. The implications and imperatives for the coming generations of physicians are compelling and of critical importance for care givers, policy makers, and most pointedly educators in the U.S. and around the world.”Gary S. Kaplan MD, Chairman and CEO, Virginia Mason Health System “This ambitious masterpiece, by one of the leading medical educators of our time, fully captures the ongoing changes and disruptions in medicine today, and how they will influence the care of patients and the training of young physicians in the future.”Eric Topol, MD, Executive Vice President, Scripps Research, Author of Deep Medicine

  • Genetics and Breeding for Disease Resistance of Livestock

    • 1st Edition
    • Aruna Pal + 1 more
    • English
    Genetics and Breeding for Disease Resistance of Livestock is a solid resource that combines important information on the underlying genetic causes and governing factors for disease resistance in food animals and applications for breeding purposes. It describes genomics at each species level to help researchers and students understand disease resistance and immunology using genomics and its application in breeding for disease resistance. This useful reference makes it easy for readers to understand and undergo further research in immunology and disease resistance for livestock. It includes novel applications and research material that is ideal for students, teachers, academicians and researchers.

  • Drug Delivery Systems

    • 1st Edition
    • English
    Drug Delivery Systems examines the current state of the field within pharmaceutical science and concisely explains the history of drug delivery systems, including key developments. The book translates the physicochemical properties of drugs into drug delivery systems administered via various routes, such as oral, parenteral, transdermal and inhalational. Regulatory and product development topics are also explored. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of drug delivery systems within the pharmaceutical sciences industry and research, as well as in chemical engineering. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists. This book provides a comprehensive examination that is suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnologies, and related industries.

  • Advanced Hematology in Integrated Cardiovascular Chinese Medicine

    Volume 3
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Advanced Hematology in Integrative Cardiovascular Chinese Medicine, volume three in the Integrative Cardiovascular Chinese Medicine series, systematically observes and discusses laboratory tests which detect heart diseases and analyzes the results. It includes coverage of red and white blood cell homeostasis and advanced anatomy and physiology of the vascular system, including the biomedicine perspectives of blood and lymphatic system, and TCM perspectives of essence, qi, blood and body fluid. In addition, the book examines the immune system from the perspective of Traditional Chinese Medicine, including pestilential differentiation. Case studies, lab charts and laboratory differentials according to Chinese and Western medicine perspectives are also included. Finally, the book discusses the use of lab results for assisting and/or confirming diagnoses of blood and cardiovascular disorders in both Traditional Chinese Medicine and Western medicine. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage collaboration.

  • Innovations and Emerging Technologies in Wound Care

    • 1st Edition
    • Amit Gefen
    • English
    Innovations and Emerging Technologies in Wound Care is a pivotal book on the prevention and management of chronic and non-healing wounds. The book clearly presents the research and evidence that should be considered when planning care interventions to improve health related outcomes for patients. New and emerging technologies are discussed and identified, along with tactics on how they can be integrated into clinical practice. This book offers readers a bridge between biomedical engineering and medicine, with an emphasis on technological innovations. It includes contributions from engineers, scientists, clinicians and industry professionals. Users will find this resource to be a complete picture of the latest knowledge on the tolerance of human tissues to sustained mechanical and thermal loads that also provides a deeper understanding of the risk for onset and development of chronic wounds.

  • Intelligent Biomechatronics in Neurorehabilitation

    • 1st Edition
    • Xiaoling Hu
    • English
    Intelligent Biomechatronics in Neurorehabilitation presents global research and advancements in intelligent biomechatronics and its applications in neurorehabilitation. The book covers our current understanding of coding mechanisms in the nervous system, from the cellular level, to the system level in the design of biological and robotic interfaces. Developed biomechatronic systems are introduced as successful examples to illustrate the fundamental engineering principles in the design. The third part of the book covers the clinical performance of biomechatronic systems in trial studies. Finally, the book introduces achievements in the field and discusses commercialization and clinical challenges. As the aging population continues to grow, healthcare providers are faced with the challenge of developing long-term rehabilitation for neurological disorders, such as stroke, Alzheimer’s and Parkinson’s diseases. Intelligent biomechatronics provide a seamless interface and real-time interactions with a biological system and the external environment, making them key to automation services.

  • Advances in Microbial Physiology

    • 1st Edition
    • Volume 75
    • Robert K. Poole
    • English
    Advances in Microbial Physiology, Volume 75, the latest release in this ongoing series, continues the long tradition of topical, important, cutting-edge reviews in microbiology. The book contains updates in the field, with comprehensive chapters covering, Sulfoxides in bacterial systems, RNA degradosomes and control by signals including c-di-GMP, Protein nanowires: biological function and synthetic constructs for ‘Green’ electronics, Bacterial nitrous oxide respiration: electron transport chains and copper transfer reactions, Multiple degrees of separation in the central pathways of the catabolism of aromatic compounds in Dikarya fungi, and more.

  • Biomedical Information Technology

    • 2nd Edition
    • David Dagan Feng
    • English
    Biomedical Information Technology, Second Edition, contains practical, integrated clinical applications for disease detection, diagnosis, surgery, therapy and biomedical knowledge discovery, including the latest advances in the field, such as biomedical sensors, machine intelligence, artificial intelligence, deep learning in medical imaging, neural networks, natural language processing, large-scale histopathological image analysis, virtual, augmented and mixed reality, neural interfaces, and data analytics and behavioral informatics in modern medicine. The enormous growth in the field of biotechnology necessitates the utilization of information technology for the management, flow and organization of data. All biomedical professionals can benefit from a greater understanding of how data can be efficiently managed and utilized through data compression, modeling, processing, registration, visualization, communication and large-scale biological computing.

  • Mucosal Vaccines

    Innovation for Preventing Infectious Diseases
    • 1st Edition
    • David W. Pascual
    • English
    Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced and discussed in an easy-to-understand format.

  • Disease Pathways

    An Atlas of Human Disease Signaling Pathways
    • 1st Edition
    • Anastasia P. Nesterova + 7 more
    • English
    Disease Pathways: An Atlas of Human Disease Signaling Pathways is designed to fill a void of illustrated reviews about the cellular mechanisms of human diseases. It covers 42 of the most common non-oncologic diseases and illustrates the connections between the molecular causes of the disease and its symptoms. This resource provides readers with detailed information about the disease molecular pathways, while keeping the presentation simple. Pathway models that aggregate the knowledge about protein–protein interactions have become indispensable tools in many areas of molecular biology, pharmacology, and medicine. In addition to disease pathways, the book includes a comprehensive overview of molecular signaling biology and application of pathway models in the analysis of big data for drug discovery and personalized medicine. This is a must-have reference for general biologists, biochemists, students, medical workers, and everyone interested in the cellular and molecular mechanisms of human disease.

  • Medical Empathy, Pharmacological Systems, and Treatment Strategies in Integrative Cardiovascular Chinese Medicine

    Volume 2
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Medical Empathy, Pharmacological Systems, and Treatment Strategies in Integrative Cardiovascular Chinese Medicine, volume two in the Integrative Cardiovascular Chinese Medicine series, presents sections on holism and humanity in medicine, considering the patient, medical empathy in prescribing, modifying and weaning, an overview of pharmacologic systems, an overview of pharmacology sciences and the cardiovascular drug classes and types as revealed from perspectives of Chinese and Western medicine, including descriptions of pharmaceutical drugs from China and the United States, with current pictures and inpatient directions. Finally, principles and treatments according to disease stages for each cardiovascular disease within the scope of integrative medicine is outlined. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine and provide a clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners

  • Kalanchoe (Crassulaceae) in Southern Africa

    Classification, Biology, and Cultivation
    • 1st Edition
    • Gideon F. Smith + 2 more
    • English
    Kalanchoe (Crassulaceae) in Southern Africa: Classification, Biology, and Cultivation provides a highly readable, illustrated account of the Kalanchoe species. The book includes an overview of the family Crassulaceae and genus Kalanchoe in global and subcontinental contexts that is followed by information on the taxonomic history of the genus. The characters and ecology of the species are also discussed, including their distribution ranges, where they occur, their habitat preferences, and where the species were formally recorded for the first time. For each indigenous and naturalized species, comprehensive taxonomic, descriptive and other information of interest is provided. This is the must-have resource for plant scientists, plant taxonomists, ethnobotanists, herbarium curators, ecologists, pharmacologists, invasions scientists, horticulturalists and landscape designers.

  • Methods of Therapeutic Drug Monitoring Including Pharmacogenetics

    • 2nd Edition
    • Volume 7
    • Georg Hempel
    • English
    Methods of Therapeutic Drug Monitoring Including Pharmacogenetics, Second Edition, Volume Seven in the Handbook of Analytical Separations series, covers all aspects of drug monitoring, including laboratory work, pharmacokinetic analysis and clinical aspects, thus enabling readers from different fields to understand the whole process of therapeutic drug monitoring and how to avoid common pitfalls. The book contains analytical techniques for the quantification of drugs, along with pharmacogenetic and pharmacogenomic methods. Also included are updates on sample preparation, including dried blood spot technology and microextraction methods. In addition, the book includes new drugs, such as tyrosine kinase inhibitors and the monitoring of immunosuppressant drugs.

  • Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine

    Volume 1
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Herbal, Bio-nutrient and Drug Titration According to Disease Stages in Integrative Cardiovascular Chinese Medicine, the first volume in the Integrative Cardiovascular Chinese Medicine series, provides a comprehensive guide to improving outcomes with cardiovascular medicine therapy options. Coverage includes the three types of medicines used in disease stage treatment, Chinese medicine, nutritional supplements and pharmaceutical drugs. All sections are organized according to drug class in western medicine and chapters in each section are organized according to disease stage, providing ease in navigation and reference within the book. This important reference will aid cardiovascular researchers in the study of integrative Chinese and western medicine as well as provide a clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.

  • Molecular Nutrition: Carbohydrates

    • 1st Edition
    • Vinood B. Patel
    • English
    Molecular Nutrition: Carbohydrates presents the nutritional and molecular aspects of carbohydrates. As part of the Molecular Nutrition includes sections covering carbohydrate metabolism, carbohydrates in the diet, insulin resistance, dietary sugars, cardiometabolic risk, lipoproteins, low-carbohydrate diets, antioxidants, refined dietary sugars, fats, glucose transporters, glucose sensing, the role of phosphorylation, carbohydrate responsive binding protein, cyclic AMP, peroxisome proliferator-activat... receptors, SIRT1, insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes rRNA and transcription, and more. In addition, the book addresses emerging fields of molecular biology and presents important discoveries relating to diet and nutritional health.

  • Neuroprotection in Autism, Schizophrenia and Alzheimer's disease

    • 1st Edition
    • Illana Gozes + 1 more
    • English
    Neuroprotection in Autism, Schizophrenia and Alzheimer's Disease provides an up-to-date overview on recent clinical studies and the similarities discovered in the most prevalent brain disorders. The book's content will help shed light on basic mechanisms and provide new avenues for early diagnosis toward disease prevention and disease modification. It is written for researchers, clinicians and medical physicians in neuroscience, neurology and psychiatry. Sections discuss the shared pathophysiological mechanisms that underlie autism, schizophrenia/mood disorders and Alzheimer’s disease, i.e. neurodevelopmental disorders, neuropsychiatric diseases and neurodegenerative disorders.

  • Tilapia Culture

    Second Edition
    • 2nd Edition
    • Abdel-Fattah M. El-Sayed
    • English
    Tilapia Culture, Second Edition, covers the vital issues of farmed tilapia in the world, including their biology, environmental requirements, semi-intensive culture, intensive culture systems, nutrition and feeding, reproduction, seed production and larval rearing, stress and disease, harvesting, economics, trade, marketing, the role of tilapia culture in rural development and poverty eradication, and technological innovations in, and the environmental impacts of, tilapia culture. In addition, the book highlights and presents the experiences of leading countries in tilapia culture, thus making it ideal for tilapia farmers and researchers who seek the most relevant research and information. The new second edition not only brings the most updated information within each chapter, but also delivers new content on tilapia transfers, introductions and their impacts, the use of probiotics and other additives in tilapia culture, tilapia trade, including marketing, and sustainability approaches and practices, such as management practices, ecosystem approaches to tilapia culture, and value chain analyses of tilapia farming.

  • Exosomes

    A Clinical Compendium
    • 1st Edition
    • Lawrence R. Edelstein + 3 more
    • English
    Exosomes: A Clinical Compendium is a comprehensive and authoritative account of exosomesin the context of biomarkers, diagnostics, and therapeutics across a wide spectrum of medicaldisciplines, as well as their role in cell-cell communication. It is intended to serve as a referencesource for clinicians, physicians, and research scientists who wish to gain insight into the mostrecent advances in this rapidly growing field. The exosome revolution may well be the greatest advance in physiology and medicine sinceantibiotics. The discovery of their epigenetic role in intercellular signaling in virtually all tissues is amajor breakthrough in our understanding of how cells function.

  • Personalized Psychiatry

    • 1st Edition
    • Bernhard Baune
    • English
    Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders.

  • DNA Repair

    • 1st Edition
    • Volume 45
    • English
    DNA Repair, Volume 45 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair, Translesion polymerases, mechanism and function, The Rev1-Polζ Mutasome: Structure and Interactions in Translesion Synthesis, Challenges for base excision repair enzymes: acquiring access to damaged DNA in chromatin Nucleotide excision repair, DNA damage recognition mechanisms in mammalian nucleotide excision repair, Advances in understanding DNA mismatch repair, and more.

  • The Autoimmune Diseases

    • 6th Edition
    • M. Eric Gershwin + 1 more
    • English
    The Autoimmune Diseases, Sixth Edition, emphasizes the "3 P’s" of 21st Century medicine: precision, prediction and prevention. Topics cover the modern systems approach to biology that involves large amounts of personalized, ongoing physiologic data ("omics") coupled with advanced methods of analysis, new tests of genetic engineering, such as CRISPR, auto inflammatory diseases, autoimmune responses to tumor immunotherapy, and information on normal immune response and disorders. Each of the major autoimmune disorders is discussed by researchers and clinical investigators experienced in dealing with patients. Chapters emphasize the immunologic basis of the disease as well as the use of immunologic diagnostic methods and treatments. The book also covers several cross-cutting issues related to the recognition and treatment of autoimmune diseases, including chapters on the measurement of autoantibodies and T cells, the use of biomarkers as early predictors of disease, and new methods of treatment.

  • Nutritional and Health Aspects of Food in Western Europe

    • 1st Edition
    • Susanne Braun + 3 more
    • English
    People were once restricted to food native to their region and produced locally. Today, however, food from any place in the world is available, or can be made available, anywhere else. Often there is no or very little information about the nutritional and health aspects of these foods. Nutrition and Health of Western European Foods: Traditional and Ethnic Diets is part of series that will cover the entire globe and is aimed at filling the knowledge gap from traditional and scientific points of view. This volume provides an analysis of traditional and ethnic foods from Western Europe, including Ireland, the United Kingdom, Netherlands, Belgium, Luxembourg, France, and Germany. It also addresses the history of use, composition, preparation, ingredient origin, nutritional aspects, and health effects of various foods and food products in each of these countries. Nutrition and Health of Western European Foods: Traditional and Ethnic Diets ultimately presents both local and international regulations, providing suggestions to harmonize these regulations and promote global availability of these foods.

  • Giardia and Giardiasis

    Part A
    • 1st Edition
    • Volume 106
    • M.Guadalupe Ortega-Pierres
    • English
    Giardia and Giardiasis, Volume 106 in Advances in Parasitology series includes in the first part aspects of molecular and cellular biology of Giardia and the role of particular molecules or molecular groups in essential functions and/or trafficking in the parasite. These approaches are with the aim to explore how this parasite adapts to an ever-changing environment both within and outside of the host animal. Subsequently a comprehensive description of virulence factors secreted by Giardia, are reviewed on their cytotoxic mechanisms and roles in the pathophysiology of giardiasis, and also a description on the potential of these secreted molecules as targets for drugs is included. In the context of the immuno-pathogenesis of giardiasis a review on the data and information on innate and adaptive immunity to Giardia, is included as well as a discussion on how improved knowledge of immunity is advancing our understanding of the pathogenesis and clinical outcomes of giardiasis. The final part of this volume includes a review of the epidemiology of giardiasis in a veterinary context using molecular tools together with a discussion of the current status of the species and assemblages of Giardia, and issues surrounding the assignment of host specificity and the zoonotic potential using current molecular markers.

  • Enzymatic Polymerizations

    • 1st Edition
    • Volume 627
    • English
    Enzymatic Polymerizations, Volume 627 in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field.

  • Epigenetic Mechanisms of the Cambrian Explosion

    • 1st Edition
    • Nelson R Cabej
    • English
    Epigenetic Mechanisms of the Cambrian Explosion provides readers with a basic biological knowledge and epigenetic explanation of the biological puzzle of the Cambrian explosion, the unprecedented rapid diversification of animals that began 542 million years ago. During an evolutionarily instant of ~10 million years, which represents only 0.3% of the time of existence of life on Earth, or less than 2% of the time of existence of metazoans, all of the 30 extant body plans, major animal groups (phyla) and several extinct groups appeared. The work helps address this phenomena and tries to answer remaining questions for evolutionary biology, epigenetics, and scientific researchers. The book recognizes and presents objective representations of alternative theories for epigenetic evolution in this period, with the author drawing on his epigenetic theory of evolution to explain the causal basis of the Cambrian explosion. Both empirical evidence and theoretical arguments are presented in support of this thought-provoking epigenetic theory.

  • Advances in Cold Plasma Applications for Food Safety and Preservation

    • 1st Edition
    • Daniela Bermudez-Aguirre
    • English
    Cold plasma is one of the newest technologies tested for food preservation. In the last decade, this novel approach has shown promising results as a disinfectant of food products and packaging materials. Cold plasma is also affordable, waterless, waste-free, and leaves no chemical residue on the product. This exciting new technology is covered thoroughly in Advances in Cold Plasma Applications for Food Preservation.The book presents the basic principles of cold plasma, examples of food products disinfected by cold plasma, and the challenges of using cold plasma to maximize microbial and spore inactivation. Some chapters are devoted to specific applications of the technology, such as the use of cold plasma for space missions. Insights about the required regulations for this technology are also discussed.Written and edited by experts in the field, Advances in Cold Plasma Applications for Food Preservation is aimed at academic researchers, food scientists, and government officials working on disinfection of food products.

  • Plasma Membrane Repair

    • 1st Edition
    • Volume 84
    • English
    Lysosomes and Membrane Function, Volume 84 in the Current Topics in Membranes series, highlights new advances in the field, with this volume presenting interesting chapters on a variety of topics, including Parasite invasion and PMR, Actin dynamics and myosin contractility during plasma membrane repair: Does one ring really heal them all?, The role of intercellular signaling in cell membrane repair, Role of lipids in plasma membrane repair, Lysosomes and plasma membrane repair, Alveolar epithelial cell membrane integrity: a venerable target in the lung, Conservative evolution of natural versus artificial PEG-induced mechanisms of PMR in eukaryotes, and more.

  • Advances in Immunology

    • 1st Edition
    • Volume 143
    • Frederick W. Alt
    • English
    Advances in Immunology, Volume 143, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on the design of vaccine strategies to elicit HIV-1 broadly neutralizing antibodies, gender bias, fungi, fibrinolysis and allergic airway inflammation, updating and interpreting airway epithelial cell reprogramming in bronchial asthma, the link(s) of sensing to the immune response, and the regulatory role of the autonomic system.

  • Exercise on Brain Health

    • 1st Edition
    • Volume 147
    • English
    Exercise on Brain Health, Volume 147 in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on Exercise on bipolar disorder in humans, Exercise on Parkinson’s disease in humans, Exercise on spinal cord injury in animals, Exercise on spinal cord injury in humans, Exercise promotes synaptic plasticity, Exercise promotes neural connectivity, Exercise on spinogenesis, Peripheral-central crosstalk of exercise on brain health, Exercise and Parkinson's, Exercise on binge alcohol consumption, Exercise on depression, and Exercise on chronic fatigue syndrome, and more.

  • Advances in Molecular Toxicology

    • 1st Edition
    • Volume 13
    • James C. Fishbein + 1 more
    • English
    Advances in Molecular Toxicology, Volume Thirteen, features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment, and produced by the human body, manifest themselves as toxins. The work not only documents these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events are also reviewed by leading experts in the field.

  • Sharks in Mexico: Research and Conservation

    • 1st Edition
    • Volume 83
    • English
    Sharks in Mexico: Research and Conservation, Volume 83 in the Advances in Marine Biology series, provides in-depth and up-to-date reviews on all aspects of marine biology that will appeal to postgraduates and researchers in marine biology, fisheries science, ecology, zoology and biological oceanography. New chapters cover The Sharks of Pacific Mexico and their Conservation - Why Should we Care?, Biodiversity and Conservation of Sharks in Pacific Mexico, Shark Ecology, The Role of the Apex Predator and Current Conservation Status, Review of Current Genetic Analyses for Sharks of Pacific Mexico and Conservation Implications, and much more.

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