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Elsevier

Books in Life sciences

  • Understanding Renal Biochemistry

    Insights from Nephrotic Syndrome to Systemic Renal Dynamics
    • 1st Edition
    • Emmanuel Kwaku Ofori + 1 more
    • English
    Understanding Renal Biochemistry: Insights from Nephrotic Syndrome to Systemic Renal Dynamics provides a comprehensive exploration of nephrotic syndrome and related renal disorders. Tailored for academicians, young researchers, and graduate/postgraduat... students worldwide in fields such as renal research, chemical pathology, medical biochemistry, pharmacology, laboratory science, and pathology, this book offers cutting-edge insights into novel diagnostic approaches, underlying pathophysiology, and effective management strategies. Enriched with real-world case studies, it bridges theoretical knowledge with practical application, empowering readers to advance their understanding and make informed decisions in the diagnosis and treatment of renal diseases. The book provides a well-structured exploration of renal biochemistry and related disciplines, guiding readers through foundational concepts to advanced research and future directions in nephrology. Authored by experts, chapters cover topics such as renal biomarkers, diagnostic precision, therapeutic interventions, and management strategies, with case studies illustrating real-world applications. Each chapter begins with a clear outline, incorporates strategic case studies, and concludes with comprehensive summaries, ensuring readers can easily grasp core concepts and benefit from practical insights, enhancing their learning experience and retention of knowledge. With each chapter supplemented by figures, tables, and case studies, this book provides a comprehensive resource for anyone seeking to deepen their understanding of renal pathophysiology and its clinical management. For scientists and researchers, the book fills a crucial gap by providing a comprehensive resource on renal pathophysiology, covering both glomerular and tubular dysfunctions, thus offering valuable insights and the latest advancements in nephrology research. For clinicians, it serves as an essential reference, offering extensive information on relevant biochemical markers for disease diagnosis, providing practical guidance to enhance clinical practice and improve patient outcomes.

  • Pediatric and Adolescent Gynecologic Surgery

    Management, Surgical Approaches, and Post-Operative Care
    • 1st Edition
    • Jennifer E Dietrich + 3 more
    • English
    Pediatric and Adolescent Gynecologic Surgery: Management, Surgical Approaches, and Post-Operative Care is an excellent and novel resource to understanding the management of adolescent gynecologic patients as written by top experts. The book offers detailed pearls of surgery and has a preoperative planning approach to abdominal, laparoscopic, and vaginal surgeries, as well as postoperative considerations. This is a comprehensive but easy-to-follow step-by-step surgical atlas for PAG surgeries organized in a historical context with the most recent research advances in the field. It provides expert views and perspectives with visuals to aid in learning useful to anyone in, or interested in, the field.

  • Diabetes and Alzheimer's Disease

    Mechanisms and Management
    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Diabetes and Alzheimer's Disease: Mechanisms and Management delves into the complex relationship between diabetes and Alzheimer’s disease. The book examines how these conditions intersect and influence each other, providing insights into their pathophysiological and epidemiological aspects. Readers will gain a thorough understanding of metabolic interactions, molecular signaling, and various factors that regulate the confluence of these diseases. Written by experts, this comprehensive guide is essential for researchers, academicians, scientists, and graduate students in biomedical and pharmaceutical sciences. In addition to exploring the mechanisms, the book discusses theranostics and strategies to manage both conditions.It includes sections on drug repositioning, dietary modifications, and the impact of metabolic dysfunction on neurological disorders.

  • Transketolases

    • 1st Edition
    • Volume 722
    • English
    Transketolase is an ubiquitous enzyme which has not yet finished revealing all its secrets. This Methods in Enzymology: Transketolases volume is devoted to the description of cutting-edge methods to its study in biochemistry. Several topics are addressed by world experts in their field.The first part of this volume deals with transketolase at the cellular level. The latest scientific progress on human transketolase TKL1 in relation to certain diseases and to its inhibition are discussed including the involvement of this enzyme in new metabolic pathways or as a diagnostic biomarker.The second part focuses on transketolase at the molecular level. The structural and mechanistic aspects linked to this enzyme are addressed using several approaches including molecular modelling and crystallography, for example. Finally, the experimental methodological approaches relating to the use of transketolase as a tool of choice in biocatalysis is presented.

  • Advances in Parasitology

    • 1st Edition
    • Volume 130
    • English
    Unveiling the Proteolytic Networks of Parasites, Volume 130 in the Advances in Parasitology series, presents a cutting-edge exploration of specific proteases across a spectrum of parasitic organisms. Top researchers in the field conduct multifaceted examinations, shedding light on the distinct roles of these proteases within significant parasite groups, including malaria, trematodes, nematodes, and blood-feeding arthropods. Chapters in this new release include The roundworm Ascaris: recent advances and progress towards elimination, Genetically modified helminths as pharmaceutical bio-factories, Epithelial cytokines in helminth infections, Schistosoma eggs: from conception to eggs-creation, Helminth extracellular vesicles: roles in and beyond parasite-host communication, and more.

  • Bioinformatics, AI, and Machine Learning in Microbial Drug Development

    • 1st Edition
    • Vagish Dwibedi + 3 more
    • English
    Bioinformatics, AI, and Machine Learning in Microbial Drug Development provides a comprehensive framework for integrating diverse fields like microbiology, bioinformatics, artificial intelligence, and machine learning, allowing readers to navigate complex interdisciplinary challenges effectively. This title offers an in-depth exploration of how these technologies are seamlessly integrated into pharmaceutical microbiology. The book, divided into 4 parts and 19 chapters, provides cutting-edge insights, practical guidance, and case studies. It emphasizes the importance of staying current with technological advancements, understanding ethical and regulatory issues, and optimizing drug production, making it an invaluable resource for industry professionals.

  • Nano-Bio-Medicine for Gastrointestinal Diseases

    • 1st Edition
    • Vivek Chaturvedi + 3 more
    • English
    Nano-Bio-Medicine for Gastrointestinal Diseases explores the transformative potential of biomedicine in gastroenterology, from innovative drug delivery systems to nanoscale imaging techniques. The book's content offers a detailed analysis of emerging technologies that are revolutionizing the diagnosis, treatment, and management of gastrointestinal disorders. By addressing conditions like inflammatory bowel disease and gastrointestinal cancers, readers gain a holistic understanding of how biomedicine is reshaping the entire landscape of gastroenterology. With a focus on personalized medicine approaches and future perspectives, this book inspires collaboration and awareness among researchers, medical practitioners, and patients, ultimately leading to improved outcomes and quality of life. Sections cover a wide range of topics that are essential for understanding the intersection of biomedicine and gastroenterology. Beginning with an introduction to NanoBioMedicine and its application in gastrointestinal diseases, readers are guided through nanoscale drug delivery systems, nanoimaging techniques, and nanotheranostics in cancer treatment. Specific chapters address the role of nanotechnology in managing conditions like inflammatory bowel disease and celiac disease, while also exploring the integration of artificial intelligence and big data analytics.

  • Health, Nutrition, and Sustainability

    Exploring Unconventional Food Sources Volume 1
    • 1st Edition
    • Tanmay Sarkar + 1 more
    • English
    Evolving dietary preferences, increasing concerns over food security and a growing awareness of the negative impact traditional food production practices have on the environment, have caused a major shift in the food landscape. Health, Nutrition and Sustainability: Exploring Unconventional Food Sources, Volume 1, addresses the surge in interest in exploring unconventional and alternative food sources that can diversify diets and become new sources of sustainable foods. From the underutilized to the lesser known, these foods are prime to improve nutrition and reduce ecological and carbon footprints. Health, Nutrition and Sustainability: Exploring Unconventional Food Sources, Volume 1, introduces readers to untapped food sources such as novel grains and seeds, underutilized fruits and vegetables, rare spices and herbs, edible invasives and edible flowers, and seaweed and microalgae and highlight their bioactive components and nutritional values. Through topics such as waste valorization, precision agriculture, organic farming and climate-smart agriculture strategies, the book also demonstrates how adaptation of underutilized plant foods play a crucial role in meeting global food security while minimizing environmental impact. The authors also navigate the readers through the safety and toxicity of these foods. A complementary volume highlighting the dietary, sensory, and gastronomic applications of unconventional foods and how they can enhance future product development is also available.

  • Genetic and Reproductive Approaches for Sustainable Livestock Production

    • 1st Edition
    • Sukanta Mondal
    • English
    Though global food demand is ever-increasing, agricultural productivity is declining, largely due to the shrinking of resources like cultivable land. Under such circumstances, the role of the livestock sector to fulfill growing food demand is particularly important for food and nutritional security. Genetic and Reproductive Approaches for Sustainable Livestock Production details the roles of both established and emerging reproductive and genomic technologies in creating more sustainable livestock production. This book outlines a variety of integrated strategies, covering traditional and modern omics approaches (structural, functional, comparative and epigenomics) and genomics-assisted breeding methods. These can be adopted and utilized to dissect and decode the gene regulatory networks involved in the quantitative yield and stress tolerance traits in livestock. Genetic and Reproductive Approaches for Sustainable Livestock Production is a particularly attractive resource for scientists, researchers, educators and professionals in livestock science, veterinary medicine, and food security. The work will allow professional readers to incorporate existing research into their practices and will prompt academics to build on existing research and make new discoveries.

  • Machine Learning in Drug Development: Part 2

    • 1st Edition
    • Volume 65
    • English
    Machine Learning in Drug Development: Part Two, Volume 65 in the Annual Reports on Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors. Chapters in this volume explore Transforming Modern Drug Discovery with Machine Learning – Applications in Ligand-based Drug Design, Optimizing Multi-Modal Drug Design Through Computational Pocket Mapping and Data Integration, Harnessing AI for Nucleic Acid Drug Discovery: Small Molecule Targeting DNA and RNA, AI-aided Drug Development for Protein Degraders: Design, Lead Identification, and Optimization, and more.Additional section delve into Artificial Intelligence in the Development of Antiviral Drugs – Progress and Applications, Artificial Intelligence for Drug Target Identification, and Machine Learning in Proteomic Biomarker Discovery

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