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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

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131-140 of 389 results in All results

Toxicogenomics-Based Cellular Models

  • 1st Edition
  • January 2, 2014
  • Jos Kleinjans
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 9 7 8 6 2 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 3 9 7 8 7 1 - 4
Toxicogenomics-Based Cellular Models is a unique and valuable reference for all academic and professional researchers employing toxicogenomic methods with respect to animal testing for chemical safety. This resource offers cutting-edge information on the application of toxicogenomics to developing alternatives to current animal toxicity tests. By illustrating the development of toxicogenomics-based cellular models for critical endpoints of toxicity and providing real-world examples for validation and data analysis, this book provides an assessment of the current state of the field, as well as opportunities and challenges for the future. Written by renowned international toxicological experts, this book explores ‘omics technology for developing new assays for toxicity testing and safety assessment and provides the reader with a focused examination of alternative means to animal testing.

Physico-Chemical Aspects of Drug Action

  • 1st Edition
  • December 28, 2013
  • E. J. Ariëns
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 2 6 9 - 1
Physico-Chemical Aspects of Drug Action, Volume 7 covers topics on drug kinetics and the overall physicochemical properties of the drug in relation therewith, and the physicochemical aspects of the drug-receptor interaction, putting emphasis on receptor mechanisms and specific properties required for certain types of drugs in this respect. The book starts with some contributions dealing with various general aspects of drug kinetics followed by some contributions dealing with the relationship between certain physicochemical properties of drug molecules and their action. The text describes the pharmacokinetics and dose-concentration relationships; the time course of the biological response to drugs; and the empirical equations for correlating biological efficiency of organic compounds. The text also describes molecular basis for the action of chemotherapeutic drugs; the structure-activity studies on sulphonamides; and the water extrusion hypothesis. The mathematical treatment of two-point attachment between drug and receptor; the molecular properties and biological activity of catecholamines and certain related compounds; and the structure-activity relationships of diarylcarbinolethers are also considered. The book further tackles quantum mechanically-derived electronic distributions in the conformers of 2-pam; and the molecular basis for the action of certain drugs in the central nervous system. Pharmacologists and chemists will find the book invaluable.

Immunopharmacology

  • 1st Edition
  • December 28, 2013
  • H. O. Schild + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 5 0 4 2 - 0
Immunopharmacology is the 11th volume of the proceedings of the Third International Pharmacological Meeting held at Sao Paulo, Brazil on July 26, 1966. The volume covers papers that deal with immunoglobulins responsible for hypersensitivity reactions and with the mechanisms of these reactions; pharmacological mediators of immediate and delayed hypersensitivity; Arthus reactions; and soluble factors released by the action of antigen on sensitized lymphocytes. The book concludes with a single paper on the subject of penicillin allergy. Immunologists and pharmacologists will find the volume invaluable.

Pharmacology of Oriental Plants

  • 1st Edition
  • December 26, 2013
  • K. K. Chen + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 4 0 - 8
Pharmacology of Oriental Plants is a collection of papers that details the advancement in research of the pharmacological properties of oriental plants. The topics included in the text cover the chemical behavior and mode of action of plants. Several studies also tackle the medicinal properties of plants that undergo a specific process. The book will be of great use to pharmacologists, botanists, biochemists, horticulturists, and physicians. Advocates of natural and alternative medicine will also find the text interesting.

Biochemical Immunological Pharmacology

  • 1st Edition
  • December 23, 2013
  • H. Yoshida + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 8 4 9 - 6
Advances in Pharmacology & Therapeutics II, Volume 4: Biochemical Immunological Pharmacology covers papers on the developments in pharmacology and therapeutics. The book contains invited lectures on the effect of drugs on immunological control mechanisms; the pharmacology of specific, pure and potent serotonin 5-HT2 or S2-antagonists; and the pharmacology of phospholipases A2 isolated from snake venoms. The text also contains papers on leukotrienes; the guanine nucleotide-binding regulatory component of adenylate cyclase; and the pharmacological and toxicological implications of multiple cytochromes P-450. The impact of the emerging biotechnologies on pharmacology; the action of antipsychotics on LSD-induced neurochemical and behavioral effects in rats; and the effect of histamine and related compounds on the immune response are also considered. The book also presents papers on inflammation; prostacyclin; prostaglandins; and chemical hazards to humans.

Advances in Immunopharmacology

  • 1st Edition
  • December 21, 2013
  • J. Hadden + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 5 3 9 - 6
Advances in Immunopharmacology documents the proceedings of the First International Conference on Immunopharmacology held in Brighton, England, in July 1980. The volume contains 60 papers organized into 10 parts. The papers in Part I examine the pharmacology of immunotherapeutic drugs and immunotoxicology. Part II presents studies on thymic hormones. Part III is devoted to immunopharmacologic approaches to diseases other than cancer. Part IV deals with mechanisms of chemotaxis degranulation and microbicidal action. Part V focuses on cancer immunopharmacology and immunotherapy while Part VI covers the mechanisms of inflammatory and allergic processes. Part VII takes up the immune testing of the actions of immunotherapeutic agents. Part VIII discusses prostaglandins and macrophage suppression. Part IX is devoted to selected topics such as mechanism of action of soluble immune response suppressor and new approaches to the therapy of allergic diseases. Part X presents discussions during the therapy communication sessions.

Handbook of Nanosafety

  • 1st Edition
  • December 17, 2013
  • Ulla Vogel + 5 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 1 6 6 0 4 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 6 6 6 2 - 2
Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment.

Perspectives in Basic and Applied Toxicology

  • 1st Edition
  • December 17, 2013
  • Bryan Ballantyne
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 9 3 5 3 - 3
Perspectives in Basic and Applied Toxicology features a collection of essays on various aspects of toxicology. It aims to relate fundamental knowledge of toxicology to its application in assessing relevance of that information to the causation of adverse health effects, predicting hazardous situations, defining protective and precautionary measures, and the recognition and management of intoxication in humans. Another objective of this volume is to encourage those with responsibility for the training of toxicologists to instill a greater concern about ethical and moral issues as fundamental to the practice of toxicology as a profession with wide-ranging social implications. This book is organized into 14 chapters. The coverage of these chapters include assessment of chemical hazards in the workplace, the relation between animal studies and epidemiology in the context of industrial toxicology, carcinogenicity testing in animals, and biochemical evaluation of neurotoxicity. This book will be of interest to undergraduate and graduate toxicologists, pharmacologists, physicians, industrial hygienists, and other health professionals.

Register for Recording Purchases and Supplies of Dangerous Drugs

  • 1st Edition
  • December 17, 2013
  • Sam Stuart
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 9 5 0 6 - 3
Register for Recording Purchases and Supplies of Dangerous Drugs is a list of registration forms for use by qualified medical practitioners, dentists, veterinarians, who can possess, supply or prepare dangerous drugs in exercise of their professions. This compilation of registration forms includes extracts from regulations made under the Dangerous Drugs Act, 1920 outlining the withdrawal of authority of an authorized person from by the Secretary of State. This book defines the form of prescription, the provisions as to dispensing of prescriptions, and the keeping of records in the register. This book also requires the authorized practitioners to preserve documents such as all registers, records, books, or prescriptions, as well as lists the preparations exempted from the regulations. These exempted preparations include Pasta Arsenicalis, B.P.C. 1934, Pil. Ipecac. c. Scila, B.P.C. 1934, Pulv. Cretae Aromat. C. Opio, B.P. 1932. The practitioner should scan and consult medical journals from time to time for any announcement of changes in the list of exempted drugs. This book lists forms for purchases and supplies for various drugs such as morphine, diamorphine, cocaine, medicinal opium, Indian hemp, Eucodal, Dicodide, Dilaudide, Desomorphine, and Pethidine. This book is intended for the use of physicians, surgeons, dentists, and veterinarians. It can also benefit pharmacists and pharmacologists.

Cleaning with Solvents: Science and Technology

  • 1st Edition
  • November 29, 2013
  • John Durkee
  • English
  • Hardback
    9 7 8 - 1 - 4 5 5 7 - 3 1 3 1 - 2
  • eBook
    9 7 8 - 1 - 4 5 5 7 - 3 1 6 1 - 9
High-precision cleaning is required across a wide range of sectors, including aerospace, defense, medical device manufacturing, pharmaceutical processing, semiconductor/electronics, etc. Cleaning parts and surfaces with solvents is simple, effective and low-cost. Although health and safety and environmental concerns come into play with the use of solvents, this book explores how safe and compliant solvent-based cleaning techniques can be implemented. A key to this is the selection of the right solvent. The author also examines a range of newer "green" solvent cleaning options. This book supplies scientific fundamentals and practical guidance supported by real-world examples. Durkee explains the three principal methods of solvent selection: matching of solubility parameters, reduction of potential for smog formation, and matching of physical properties. He also provides guidance on the safe use of aerosols, wipe-cleaning techniques, solvent stabilization, economics, and many other topics. A compendium of blend rules is included, covering the physical, chemical, and environmental properties of solvents.

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