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Books in Toxicology

Elsevier's Toxicology collection provides essential insights for researchers and scientists into mitigating the adverse effects of contaminants on organisms, covering research, analysis, risk assessment, detection, prevention, diagnosis, and treatment of toxic exposure. Including toxicity testing, environmental toxicology it offers valuable knowledge for addressing public health and safety challenges by examining the adverse effects of contaminants on human health, animals, and the environment.

121-130 of 389 results in All results

Biochemical Ecotoxicology

  • 1st Edition
  • July 2, 2014
  • Francois Gagne
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 1 1 6 0 4 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 1 6 2 3 - 8
Biochemical Ecotoxicology: Principles and Methods presents practical approaches to biochemical ecotoxicology experiments for environmental protection and conservation. With its methodical, stepped approach this essential reference introduces readers to current techniques for toxicity endpoint testing, suitable for laboratories of any size and budget. Each chapter presents a state-of-the-art principle, a quick and inexpensive procedure (including appropriate reagents), case studies, and demonstrations on how to analyze your results. Generic techniques are covered, suitable for a variety of organisms, as well as high-throughput techniques like quantitative polymerase chain reactions and enzyme-linked immunoassays. Cutting-edge approaches, including gPCR arrays and lipidomic techniques, are also included, making this is an essential reference for anyone who needs to assess environmental toxicity.

Applied Dermatotoxicology

  • 1st Edition
  • June 20, 2014
  • Howard I. Maibach + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 4 2 0 1 3 0 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 4 2 0 1 9 9 - 6
Applied Dermatotoxicology: Clinical Aspects provides concise, systematic, and state-of-the-art information on the toxicological effects of substances on skin, and recent advances in dermal toxicity testing. This book specifically addresses the clinical presentations borne out of exposure to a variety of chemicals. It begins with an overview of skin biology to provide toxicologists with a basic understanding of its anatomy and physiology. Next it presents a variety of dermatotoxicological effects, as well at the toxic agents that cause them, with color photographs to illustrate these effects. Applied Dermatotoxicology: Clinical Aspects is an essential reference for toxicologists in industry, and for those medical professionals who encounter cases of dermal exposure to toxic agents.

Toxicological Survey of African Medicinal Plants

  • 1st Edition
  • May 30, 2014
  • Victor Kuete
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 0 0 1 8 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 7 5 - 3
Toxicological Survey of African Medicinal Plants provides a detailed overview of toxicological studies relating to traditionally used medicinal plants in Africa, with special emphasis on the methodologies and tools used for data collection and interpretation. The book considers the physical parameters of these plants and their effect upon various areas of the body and human health, including chapters dedicated to genotoxicity, hepatotoxicity, nephrotoxicity, cardiotoxicity, neurotoxicity, and specific organs and systems.Following this discussion of the effects of medicinal plants is a critical review of the guidelines and methods in use for toxicological research as well as the state of toxicology studies in Africa. With up-to-date research provided by a team of experts, Toxicological Survey of African Medicinal Plants is an invaluable resource for researchers and students involved in pharmacology, toxicology, phytochemistry, medicine, pharmacognosy, and pharmaceutical biology.

History of Toxicology and Environmental Health

  • 1st Edition
  • May 22, 2014
  • Philip Wexler
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 0 0 4 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 0 4 6 3 - 0
Toxicology in Antiquity is the first in a series of short format works covering key accomplishments, scientists, and events in the broad field of toxicology, including environmental health and chemical safety. This first volume sets the tone for the series and starts at the very beginning, historically speaking, with a look at toxicology in ancient times. The book explains that before scientific research methods were developed, toxicology thrived as a very practical discipline. People living in ancient civilizations readily learned to distinguish safe substances from hazardous ones, how to avoid these hazardous substances, and how to use them to inflict harm on enemies. It also describes scholars who compiled compendia of toxic agents.

Introduction to Biostatistics

  • 1st Edition
  • May 19, 2014
  • Ronald N. Forthofer + 1 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 2 - 9 6 7 4 - 6
The Biostatistics course is often found in the schools of public Health, medical schools, and, occasionally, in statistics and biology departments. The population of students in these courses is a diverse one, with varying preparedness. The book assumes the reader has at least two years of high school algebra, but no previous exposure to statistics is required.Written for individuals who might be fearful of mathematics, this book minimizes the technical difficulties and emphasizes the importance of statistics in scientific investigation. An understanding of underlying design and analysis is stressed. The limitations of the research, design and analytical techniques are discussed, allowing the reader to accurately interpret results. Real data, both processed and raw, are used extensively in examples and exercises. Statistical computing packages - MINITAB, SAS and Stata - are integrated. The use of the computer and software allows a sharper focus on the concepts, letting the computer do the necessary number-crunching.

Toxicological Aspects of Drug-Facilitated Crimes

  • 1st Edition
  • March 20, 2014
  • Pascal Kintz
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 4 1 6 7 4 8 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 4 1 6 9 6 9 - 2
Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology.

Therapeutic Risk Management of Medicines

  • 1st Edition
  • March 13, 2014
  • Stephen J. Mayall + 1 more
  • English
  • Hardback
    9 7 8 - 1 - 9 0 7 5 6 8 - 4 8 - 0
  • eBook
    9 7 8 - 1 - 9 0 8 8 1 8 - 2 7 - 0
Therapeutic risk management of medicines is an authoritative and practical guide on developing, implementing and evaluating risk management plans for medicines globally. It explains how to assess risks and benefit-risk balance, design and roll out risk minimisation and pharmacovigilance activities, and interact effectively with key stakeholders.A more systematic approach for managing the risks of medicines arose following a number of high-profile drug safety incidents and a need for better access to effective but potentially risky treatments. Regulatory requirements have evolved rapidly over the past decade. Risk management plans (RMPs) are mandatory for new medicinal products in the EU and a Risk Evaluation and Mitigation Strategy (REMS) is needed for certain drugs in the US.This book is an easy-to-read resource that complements current regulatory guidance, by exploring key areas and practical implications in greater detail. It is structured into chapters encompassing a background to therapeutic risk management, strategies for developing RMPs, implementation of RMPs, and the continuing evolution of the risk management field.The topic is of critical importance not only to the pharmaceutical and biotechnology industries, but also regulators and healthcare policymakers.Some chapters feature contributions from selected industry experts.

Encyclopedia of Toxicology

  • 3rd Edition
  • March 11, 2014
  • Philip Wexler
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 8 6 4 5 4 - 3
The third edition of the Encyclopedia of Toxicology, Four Volume Set presents entries devoted to key concepts and specific chemicals, and is updated to reflect current advances in the field. It contains new information on nanotoxicology, epigenetics, persistent organic pollutants, computational toxicology and bioinformatics, controversial chemicals, and much more. Along with the traditional scientific entries, new articles focus on worldwide initiatives, the potential health and environmental effects of new technologies, and the societal implications of global legal and regulatory issues. With thoroughly updated articles, references, and resources for recommended reading, the third edition has been expanded in length, breadth, and depth, and continues to provide an extensive overview of the many facets of toxicology.

Pharmacology of Cholinergic and Adrenergic Transmission

  • 1st Edition
  • February 14, 2014
  • G. B. Koelle + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 5 3 9 - 2
Section on Pharmacology of the International Union of Physiological Sciences (SEPHAR), Proceedings of the Second International Pharmacological Meeting, August 20-23, 1963, Volume 3: Pharmacology of Cholinergic and Adrenergic Transmission focuses on the effects of drugs on muscles, nerve fibers, and the central nervous system. The selection first offers information on the role of sodium ions in the release of acetylcholine and the distribution and release of acetylcholine in muscles. Discussions focus on the effects of sodium deficiency on ACh release in perfused ganglia; effects of sodium pump inhibitors on ganglionic and myoneural transmission; distribution of ACh and choline acetylase in muscle; and ACh release after denervation. The text then ponders on the roles of acetylcholine and acetylcholinesterase in junctional transmission and correlated studies of monoamines and acetylcholinesterase in sympathetic ganglia, manifesting the distribution of adrenergic and cholinergic neurons. The publication examines the action of acetylcholine and related drugs on mammalian nonmyelinated nerve fibers; possible mechanisms of acetylcholine action in muscles; and electrophysiological analysis of cholinergic transmission in sympathetic ganglia. The text then reviews the interactions of cholinomimetic and cholinergic blocking drugs at sympathetic ganglia; evolution of cholinoreceptive sites of locomotor muscle; and pharmacological blocking of central cholinoreactive systems and the possibilities of its therapeutic application. The selection is a dependable source of data for readers interested in the pharmacology of cholinergic and adrenergic transmission.

Biomarkers in Toxicology

  • 1st Edition
  • January 25, 2014
  • Ramesh C Gupta
  • English
  • eBook
    9 7 8 - 0 - 1 2 - 4 0 4 6 4 9 - 8
Biomarkers in Toxicology is a timely and comprehensive reference dedicated to all aspects of biomarkers that relate to chemical exposure and their effects on biological systems. This book includes both vertebrate and non-vertebrate species models for toxicological testing and development of biomarkers. Divided into several key sections, this reference volume contains chapters devoted to topics in molecular-cellular toxicology, as well as a look at the latest cutting-edge technologies used to detect biomarkers of exposure and effects. Each chapter also contains several references to the current literature and important resources for further reading. Given this comprehensive treatment, Biomarkers in Toxicology is an essential reference for all those interested in biomarkers across several scientific and biomedical fields.