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Books in Toxicology general

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61-70 of 300 results in All results

Alcohol, Drugs, Genes and the Clinical Laboratory

  • 1st Edition
  • October 17, 2016
  • Amitava Dasgupta
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 5 4 5 5 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 9 3 3 4 - 4
Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials.

Fundamentals of Toxicology

  • 1st Edition
  • August 24, 2016
  • P.K. Gupta
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 0 5 4 0 3 - 1
Fundamentals of Toxicology: Essential Concepts and Applications provides a crisp, easy-to-understand overview of the most important concepts, applications, and ideas needed to learn the basics of toxicology. Written by a pre-eminent toxicologist with over five decades of teaching experience, this comprehensive resource offers the hands-on knowledge needed for a strong foundation in the wide field of toxicology. Fundamentals of Toxicology includes a clear structure divided into five units to assist learning and understanding. The first unit provides extensive coverage on the background of toxicology including commonly used definitions and historical perspective, while following units cover: basic concepts; regulatory requirements and good laboratory practices, including types of toxicology testing and evaluation; toxic agents and adverse effects on health; and analytical, forensic, and diagnostic toxicology. This is an essential book for advanced students in toxicology and across the biomedical sciences, life sciences, and environmental sciences who want to learn the concepts of toxicology, as well as early researchers needing to refresh outside of their specialty.

Molecular Biological Markers for Toxicology and Risk Assessment

  • 1st Edition
  • June 8, 2016
  • Bruce A. Fowler
  • English
  • Hardback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 0 1 9 0 1 - 6
Molecular Biological Markers for Toxicology and Risk Assessment provides an introduction to the exciting field of biomarkers and their use in toxicology and risk assessment. In recent years, new classes of molecular biomarkers capable of detecting early manifestations of ongoing chemical-induced cell injury and cell death have been developed as a result of advances in analytical chemistry, molecular biology, and computational modeling. The interplay between these emergent tools of science has resulted in new insights into initial mechanisms of chemical-induced toxicity and carcinogenicity. Molecular Biological Markers for Toxicology and Risk Assessment guides the reader through a broad range of molecular biological markers, including the "omic" biomarkers, and provides an examination of the various elements in the evolution of these modern tools. It then explores possible ways in which these markers may be applied to advance the field of chemical risk assessment. Since molecular biomarkers and related technologies are inherently complex, the book concludes with a section on risk communication in order that readers may appreciate both the strengths and limitations of molecular biological marker approaches to risk assessment practice.

Clinical Challenges in Therapeutic Drug Monitoring

  • 1st Edition
  • May 17, 2016
  • William Clarke + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 0 2 0 2 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 2 0 5 2 - 4
Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions and Pharmacogenomics focuses on critical issues in therapeutic drug monitoring including special requirements of therapeutic drug monitoring important to special populations (infants and children, pregnant women, elderly patients, and obese patients). The book also covers issues of free drug monitoring and common interferences in using immunoassays for therapeutic drug monitoring. This book is essential reading for any clinician, fellow, or trainee who wants to gain greater insight into the process of therapeutic drug monitoring for individual dosage adjustment and avoiding drug toxicity for certain drugs within a narrow therapeutic window. The book is written specifically for busy clinicians, fellows, and trainees who order therapeutic drug monitoring and need to get more familiar with testing methodologies, issues of interferences, and interpretation of results in certain patient populations.

Atlas of Histology of the Juvenile Rat

  • 1st Edition
  • May 4, 2016
  • George A Parker + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 2 6 8 2 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 0 2 6 9 6 - 0
Atlas of Histology of the Juvenile Rat should be of interest to toxicologic pathologists, toxicologists, and other biological scientists who are interested in the histomorphology of juvenile rats. For several decades the laboratory rat has been used extensively in nonclinical toxicology studies designed to detect potential human toxicity of drugs, agrochemicals, industrial chemicals, and environmental hazards. These studies traditionally have involved young adult rats that are 8-10 weeks of age as studies are started. It is becoming increasingly apparent that children and young animals may have different responses to drug/chemical exposures, therefore, regulatory agencies are emphasizing toxicology studies in juvenile animals. While the histologic features of organs from young adult and aged laboratory rats are well known, less is known about the histologic features of organs from juvenile rats. Final histologic maturity of many organs is achieved postnatally, thus immature histologic features must be distinguished from chemical- or drug-related effects. While this postnatal organ development is known to exist as a general concept, detailed information regarding postnatal histologic development is not readily available. The Atlas includes organs that are typically sampled in nonclinical toxicology studies and presents the histologic features at weekly intervals, starting at birth and extending through postnatal day 42.

Abstracts

  • 1st Edition
  • April 19, 2016
  • J. R. Boissier + 2 more
  • English
  • eBook
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Abstracts contains the abstracts of work presented at the 7th International Congress of Pharmacology: invited lectures, symposia, methodological seminars, and free communications. The abstracts are organized in chronological order of presentation at the Congress. Some abstracts focus on chemistry and biochemistry of pituitary endorphins and their precursors; the biosynthesis and release of the enkephalins; enkephalin dynamics and neuronal localization; and physiological and pathophysiological relevance of the opiate receptors and their endogenous ligands. Other papers center on the mechanism of muscarinic receptor action; regulation of cholinergic receptor metabolism in skeletal muscle; the role of vitamin E in ozone-induced pulmonary toxicity; alcohol and electrophysiology of the central nervous system; and pharmacokinetic aspects of drug-alcohol interaction.

Engineered Nanoparticles

  • 1st Edition
  • November 24, 2015
  • Ashok K. Singh
  • English
  • Paperback
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  • eBook
    9 7 8 - 0 - 1 2 - 8 0 1 4 9 2 - 9
Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an indispensable introduction to engineered nanomaterials (ENM) and their potential adverse effects on human health and the environment. Although research in the area of pharmacology and toxicology of ENM is rapidly advancing, a possible correlation between their physicochemical properties and biomedical properties or toxicity is not yet fully understood. This understanding is essential to develop strategies for the safe applications and handling of ENM. The book comprehensively defines the current understanding of ENM toxicity, first describing these materials and their physicochemical properties, and then discussing the toxicological theory and methodology before finally demonstrating the potential impact of ENM on the environment and human health. It represents an essential reference for students and investigators in toxicology, pharmacology, chemistry, material sciences, medicine, and those in related disciplines who require an introduction to ENM and their potential toxicological effects.

Advances in Molecular Toxicology

  • 1st Edition
  • Volume 9
  • October 11, 2015
  • James C. Fishbein + 1 more
  • English
  • Hardback
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  • eBook
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Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field.

Case Studies in Nanotoxicology and Particle Toxicology

  • 1st Edition
  • May 26, 2015
  • Antonietta M Gatti + 1 more
  • English
  • Hardback
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  • eBook
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Case Studies in Nanotoxicology and Particle Toxicology presents a highly-illustrated analysis of the most prominent cases on the adverse effects of nanoparticles and their impact on humans and the environment. This comprehensive reference demonstrates the possible risks imposed by managing and handling nanoparticles, showing the effects of involuntary inhalation or ingestion during their use and after their incineration. Through the use of numerous examples, readers will discover the possible risks and effects of working with nanoparticles, along with best practices to prevent these effects. The text is an essential reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians.

Basic Pharmacology

  • 3rd Edition
  • May 11, 2015
  • R W Foster
  • English
  • eBook
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Basic Pharmacology, Third Edition aims to present accounts of drug actions and their mechanisms in a compact, inexpensive, and updated form, and explain the basis of the therapeutic exploitation of drugs. This book is divided into sections that follow a particular theme and is introduced by the relevant pharmacological general principles. In each section, the major groups of drugs related to the theme are discussed with detailed expositions of the important “type” substances. Drugs of lesser importance are placed in proper context. A list of abbreviations that are referenced throughout the book is provided after the introduction. An index is also included at the end. This edition is designed to help students taking pharmacology, including medical students of subjects affiliated to medicine, to appreciate the rationale underlying the uses of drugs in therapeutics.

Related subjects

Toxicology