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Books in Pharmacology general

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Anticandidal Agents

  • 1st Edition
  • September 12, 2016
  • Awanish Kumar
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 1 3 1 1 - 0
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 1 3 1 2 - 7
Anticandidal Agents provides the latest information on candida drug resistance and its remedial implications. In this compilation, users will find a comprehensive view on overcoming resistance in anticandidal drugs, along with information on novel molecules. Candida albicans is an opportunistic pathogenic fungus responsible for life threating invasive and nosocomial infections across the globe. Candidiasis is a major cause of morbidity among immunocompromised patients. Infections caused by non-albicans candida like C. glabrata, C. parapsilosis, and C. tropicalis have also imposed a serious threat in the last few decades. Current treatment of candidiasis relies primarily on antifungal agents broadly categorized as azoles, polyenes, echinocandins, allylamines, and pyrimidines. Lately, antifungal resistance has emerged to be an obstruction of current treatment regime. A number of reasons are described in detail. Understanding the mechanisms of resistance is crucial for developing strategies for overcoming the hindrance in current therapeutics.

Pyrantel Parasiticide Therapy in Humans and Domestic Animals

  • 1st Edition
  • June 2, 2016
  • Alan A. Marchiondo
  • English
  • Paperback
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  • eBook
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Pyrantel Parasiticide Therapy in Humans and Domestic Animals presents a single source history and reference on the parasiticide activity and pharmacology of the tetrahydropyrimidines and their salts in humans and domestic animals, also collating evidence that resistance to pyrantel has developed in human and domestic animal nematodes. Other books of this nature have been compiled historically for specific anthelmintic compounds, but none has been written to date for the pyrantel family of drugs. Pyrantel, a nicotinic receptor agonist, has been used in domestic animal and human medicine since the 1970’s to control two important nematode groups, the hookworms and the roundworms. Given the zoonotic potential of these parasites, pyrantel has served a dual role in helping to protect the health of both domestic animals and the public for more than 45 years.

Psychopharmacology of Anxiolytics and Antidepressants

  • 1st Edition
  • April 20, 2016
  • S.E. File
  • English
  • eBook
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Contributed volume reviewing the clinical and animal literature related to the pharmacology of anxiety and depression. The role of the hypothalmic-pituitary-adrenal axis in anxiety and depression is reviewed as well as the response of central catecholamines to chronic stress.

Pharmacological Mechanisms and the Modulation of Pain

  • 1st Edition
  • Volume 75
  • February 23, 2016
  • James E Barrett
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 0 3 8 8 3 - 3
  • eBook
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Pharmacological Mechanisms and the Modulation of Pain, the newest volume in the Advances in Pharmacology series, presents the pharmacological mechanisms and the modulation of pain. With a variety of chapters and the best authors in the field, this volume is an essential resource for pharmacologists, immunologists, and biochemists alike.

Advances in Immunopharmacology

  • 1st Edition
  • January 22, 2016
  • L. Chedid + 4 more
  • English
  • eBook
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With the publication of this third volume in the series, immunopharmacology has established itself as a separate discipline with relevance to oncology, rheumatology, allergy and other medical fields. The manipulation of the immune response is becoming the basis of all modern therapeutics. This volume gathers together symposia and workshop sessions, representing a comprehensive review of the advancing frontier of immunopharmacology.

Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

  • 1st Edition
  • Volume 74
  • July 23, 2015
  • James P Hardwick
  • English
  • Hardback
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  • eBook
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Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer.

Modern Applications of Plant Biotechnology in Pharmaceutical Sciences

  • 1st Edition
  • July 22, 2015
  • Saurabh Bhatia + 3 more
  • English
  • Paperback
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  • eBook
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Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications.

Essential Pharmacokinetics

  • 1st Edition
  • March 25, 2015
  • Thorsteinn Loftsson
  • English
  • eBook
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Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients.

TRP Channels as Therapeutic Targets

  • 1st Edition
  • March 14, 2015
  • Arpad Szallasi
  • English
  • Hardback
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  • eBook
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TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings.

Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B

  • 1st Edition
  • Volume 73
  • January 22, 2015
  • Uwe Rudolph
  • English
  • Hardback
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  • eBook
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Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B, a new volume of Advances in Pharmacology, presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years, which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.

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