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Books in Drug design

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11-20 of 52 results in All results

Coronavirus Drug Discovery

  • 1st Edition
  • July 6, 2022
  • Chukwuebuka Egbuna
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 5 5 7 8 - 2
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 5 5 7 9 - 9
Coronavirus Drug Discovery, Volume Three: Druggable Targets and In Silico Update presents comprehensive information on drug discovery against COVID-19. Chapters in Part One of this volume describe the various druggable targets and associated signaling pathways for effective targeting of SARS-CoV-2. In Part Two, chapters discuss the various computational approaches and in silico studies against SARS-CoV-2. Written by global team of experts, this book is an excellent resource that will be extremely useful to drug developers, medicinal chemists, pharmaceutical companies in R&D, research institutes in both academia and industry, and the National Library of Medicines and Health. In addition, agencies such as the National Institutes of Health, Centers for Disease Control and Prevention, World Health Organization, European Medicines Agency, the US Food and Drug Administration, and all others involved in drug discovery against COVID-19 will find this book useful.

Combination Drug Delivery Approach as an Effective Therapy for Various Diseases

  • 1st Edition
  • March 27, 2022
  • Prashant Kesharwani
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 8 7 3 - 1
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 8 7 6 - 2
Combination Drug Delivery Approach as an Effective Therapy for Various Diseases explores the use of bioengineering tools in combination drug delivery approaches to control various diseases at different clinical stages of synergistic action, varying mechanisms of action, and during the suppression of drug resistance. The book presents fundamental knowledge on the experiential and experimental aspects of drug combination approaches in order to equip rational applications in preventing the emergence of resistance during the treatment of various diseases. It provides a holistic understanding of the principles behind formation, characterization, applications, regulations, toxicity, challenges and future perspectives of combination drug delivery approaches. It will be of interest to researchers and advanced graduate students in pharmaceutical science, chemistry, biology and medicine, as well as pharmaceutical companies and scientific organizations.

Nanotherapeutics in Cancer Vaccination and Challenges

  • 1st Edition
  • March 3, 2022
  • Mahfoozur Rahman + 4 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 6 8 6 - 4
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 6 8 7 - 1
Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy.

Pharmacokinetics and Toxicokinetic Considerations - Vol II

  • 1st Edition
  • February 5, 2022
  • Rakesh Kumar Tekade
  • English
  • Hardback
    9 7 8 - 0 - 3 2 3 - 9 8 3 6 7 - 9
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 3 1 6 - 4
Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.

Systemic Drug Delivery Strategies

  • 1st Edition
  • August 21, 2021
  • Mansoor M. Amiji + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 7 8 1 - 9
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 0 9 2 5 - 9
Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 examines the challenges of delivering immuno-oncology therapies, focusing specifically on the multiple technologies of affective drug delivery strategies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. This volume of Delivery Strategies and Engineering Technologies in Cancer Immunotherapy discusses methods of targeting tumors, CRISPR technology, and vaccine delivery among many other delivery strategies. Systemic Drug Delivery Strategies: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy, Volume 2 creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.

Nano-Pharmacokinetics and Theranostics

  • 1st Edition
  • July 28, 2021
  • Nanasaheb D. Thorat + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 0 5 0 - 6
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 5 9 8 2 - 0
Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy addresses from a comprehensive and multidisciplinary approach the translational aspects and clinical perspectives of nano-pharmacokinetics using cancer as a model disease. Nano-pharmacokinetics is emerging as an important sub discipline of nanoscience and medical sciences because of the increasing safety issues of nanosystems on living organisms. This book reports the dynamics of nanosystems in living organisms for better understanding of nanotoxicity, pharmacology, biochemistry, physiology and medicine perspectives. It further examines current progress of state-of-the art pharmacokinetics mechanisms, which will be of great help to develop more clinical-oriented nanosystems with a wide safety margin. The book is divided into three sections: the first section focuses on the concept of pharmacokinetics with state-of-the-art Nano-Pharmacokinetics (NPK). The second section looks at the engineering of nanoparticles and pharmacokinetics clinical development. The final section focuses on Nano-Pharmacokinetics and Theranostics, elaborating the basic question of how pharmacokinetics of nanomaterials relate to their end applications such as cancer therapy. Nano-Pharmacokinetics and Theranostics: Advancing Cancer Therapy will be useful to researchers in the field of nanoparticle based targeted drug delivery including pharmaceutical scientists, material scientists, chemists, nanotechnologists, biomedical scientists, and clinicians.

Multifunctional Theranostic Nanomedicines in Cancer

  • 1st Edition
  • March 16, 2021
  • Malay K. Das
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 7 1 2 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 7 0 0 - 9
Multifunctional Theranostic Nanomedicines in Cancer focuses on new trends, applications, and the significance of novel multifunctional nanotheranostics in cancer imaging for diagnosis and treatment. Cancer nanotechnology offers new opportunities for cancer diagnosis and treatment. Multifunctional nanoparticles harboring various functions—including targeting, imaging, and therapy—have been intensively studied with the goal of overcoming the limitations of conventional cancer diagnosis and therapy. Thus theranostic nanomedicines have emerged in recent years to provide an efficient and safer alternative in cancer management. This book covers polymer-based therapies, lipid-based therapies, inorganic particle-based therapies, photo-related therapies, radiotherapies, chemotherapies, and surgeries. Multifunctional Theranostic Nanomedicines in Cancer offers an indispensable guide for researchers in academia, industry, and clinical settings; it is also ideal for postgraduate students; and formulation scientists working on cancer.

The Design and Development of Novel Drugs and Vaccines

  • 1st Edition
  • January 21, 2021
  • Tarun Kumar Bhatt + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 4 7 1 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 4 7 5 - 6
The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval.

An Industrial IoT Approach for Pharmaceutical Industry Growth

  • 1st Edition
  • May 15, 2020
  • Valentina Emilia Balas + 2 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 3 2 6 - 1
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 3 2 7 - 8
An Industrial IoT Approach for Pharmaceutical Industry Growth, Volume Two uses an innovative approach to explore how the Internet of Things (IoT) and big data can improve approaches and make discoveries. Rapid growth of the IoT has encouraged many companies in the manufacturing sector to make use of this technology to unlock its potential. Using clear language and real-world case studies, this book discusses systems level from both a human-factors point-of-view and the perspective of networking, databases, privacy and anti-spoofing. The wide variety in topics presented offers multiple perspectives on how to integrate the Internet of Things into pharmaceutical manufacturing.This book represents a useful resource for researchers in pharmaceutical sciences, information and communication technologies, and those who specialize in healthcare and pharmacovigilance.

Cancer-Leading Proteases

  • 1st Edition
  • January 9, 2020
  • Satya Prakash Gupta
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 1 6 8 - 3
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 8 1 6 9 - 0
Cancer-Leading Proteases: Structures, Functions, and Inhibition presents a detailed discussion on the role of proteases as drug targets and how they have been utilized to develop anticancer drugs. Proteases possess outstanding diversity in their functions. Because of their unique properties, proteases are a major focus of attention for the pharmaceutical industry as potential drug targets or as diagnostic and prognostic biomarkers. This book covers the structure and functions of proteases and the chemical and biological rationale of drug design relating to how these proteases can be exploited to find useful chemotherapeutics to fight cancers. In addition, the book encompasses the experimental and theoretical aspects of anticancer drug design based on proteases. It is a useful resource for pharmaceutical scientists, medicinal chemists, biochemists, microbiologists, and cancer researchers working on proteases.