Pharmacokinetics and Toxicokinetic Considerations - Vol II
- 1st Edition - February 5, 2022
- Imprint: Academic Press
- Editor: Rakesh Kumar Tekade
- Language: English
- Hardback ISBN:9 7 8 - 0 - 3 2 3 - 9 8 3 6 7 - 9
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 1 3 1 6 - 4
Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research.… Read more
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Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices.
Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists.
- Allows readers to systematically integrate up-to-date research findings into their laboratory work
- Presents focused explorations of bioanalytical methods for bioavailability and bioequivalence assessment
- Provides clinical applications of concepts
Researchers in pharmacokinetics and scientists who work on animals from both academia and industry; Researchers and advanced students in Pharmaceutical Sciences, Bioengineering, Pharmacology, Drug Development and Chemistry
1. Basic principles and concept in Toxicokinetic
Muktika Tekade
2. Factors Influencing Drug Toxicity
Muktika Tekade
3. Molecular biology of apoptotic, necrotic and necroptotic cell death
Muktika Tekade
4. Toxicogenomic in drug safety assessment
Muktika Tekade
5. Understanding the concept of signal toxicity
Muktika Tekade
6. Importance of toxicity testing
Muktika Tekade
7. Methods and Models for in vitro toxicity
Muktika Tekade
8. New Emerging technologies for genetic toxicity testing
Muktika Tekade
9. Zebrafish models for toxicological screening
Muktika Tekade
10. Impact of ageing on the pharmacokinetics and pharmacodynamics of the drugs
Muktika Tekade
11. Food-Drug Interactions and their Implications on Oral Drug Bioavailability
Muktika Tekade
12. Drug-Drug interactions and their implications on the Pharmacokinetics of the Drugs
Muktika Tekade
13. Clinical Importance of Herb-Drug interaction
Muktika Tekade
14. Insilico methods for the prediction of drug toxicity
Muktika Tekade
15. Organ-on-a-chip for assessing environmental toxicants
Muktika Tekade
16. Toxicity and toxicokinetics consideration in product development and drug research
Muktika Tekade
17. Drug Toxicity and Forensic Pharmacokinetics
Rakesh Tekade
18. Excipient’s toxicity and safety
Muktika Tekade
19. Pharmaceutical excipients: Special focus on Adverse drug interactions
Muktika Tekade
20. Emerging role of novel excipients in drug product development and their safety concerns
Muktika Tekade
21. Toxicity of Pharmaceutical azo dyes
Rakesh Tekade
22. Environmental and Safety Aspects of Bionanotechnology
Rakesh Tekade
23. Toxicological Risk assessment of medical devices
Rakesh Tekade
24. Developmental toxicity of nanomaterials used in healthcare
Rakesh Tekade
25. Ethical defilements in clinical research and potential roles of Institutional review board
Rakesh Tekade
26. Toxicodynamic in Drug research
Muktika Tekade
Muktika Tekade
2. Factors Influencing Drug Toxicity
Muktika Tekade
3. Molecular biology of apoptotic, necrotic and necroptotic cell death
Muktika Tekade
4. Toxicogenomic in drug safety assessment
Muktika Tekade
5. Understanding the concept of signal toxicity
Muktika Tekade
6. Importance of toxicity testing
Muktika Tekade
7. Methods and Models for in vitro toxicity
Muktika Tekade
8. New Emerging technologies for genetic toxicity testing
Muktika Tekade
9. Zebrafish models for toxicological screening
Muktika Tekade
10. Impact of ageing on the pharmacokinetics and pharmacodynamics of the drugs
Muktika Tekade
11. Food-Drug Interactions and their Implications on Oral Drug Bioavailability
Muktika Tekade
12. Drug-Drug interactions and their implications on the Pharmacokinetics of the Drugs
Muktika Tekade
13. Clinical Importance of Herb-Drug interaction
Muktika Tekade
14. Insilico methods for the prediction of drug toxicity
Muktika Tekade
15. Organ-on-a-chip for assessing environmental toxicants
Muktika Tekade
16. Toxicity and toxicokinetics consideration in product development and drug research
Muktika Tekade
17. Drug Toxicity and Forensic Pharmacokinetics
Rakesh Tekade
18. Excipient’s toxicity and safety
Muktika Tekade
19. Pharmaceutical excipients: Special focus on Adverse drug interactions
Muktika Tekade
20. Emerging role of novel excipients in drug product development and their safety concerns
Muktika Tekade
21. Toxicity of Pharmaceutical azo dyes
Rakesh Tekade
22. Environmental and Safety Aspects of Bionanotechnology
Rakesh Tekade
23. Toxicological Risk assessment of medical devices
Rakesh Tekade
24. Developmental toxicity of nanomaterials used in healthcare
Rakesh Tekade
25. Ethical defilements in clinical research and potential roles of Institutional review board
Rakesh Tekade
26. Toxicodynamic in Drug research
Muktika Tekade
- Edition: 1
- Published: February 5, 2022
- Imprint: Academic Press
- Language: English
RT
Rakesh Kumar Tekade
Dr Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, investigates the design, development and characterization of targeted nanotechnology based formulations for the site specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, proteins and peptide for the treatment of cancer. His current research encompasses development of novel polymeric nanomaterial for effective cytosolic delivery of anticancer bioactives. Dr Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. Dr Tekade has over 70 publications, 01 patent, 7 book chapters, and 3 editorial articles. He has delivered several invited research talks and presented research finding in more than 30 scientific conferences.
Affiliations and expertise
Assistant Professor, Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research Ahmedabad, Gujarat, IndiaRead Pharmacokinetics and Toxicokinetic Considerations - Vol II on ScienceDirect