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Books in Neuropharmacology

Focusing on drug mechanisms, development, and therapeutic targets in the nervous system, this portfolio supports pharmacologists, neuroscientists, and clinicians. It features innovations in neurodrug delivery, receptor modulation, and treatment of neurological and psychiatric conditions.

  • Pharmacology of 5-HT6 receptors, Part I

    • 1st Edition
    • Volume 94
    • English
    The serotonin 5-HT6 receptor represents a novel pharmacological target whose impact on physiopathology of CNS functions remains undetermined. Some receptor antagonists have been synthesized and they show a modulatory role in learning and memory processes and food intake. The pharmacology of 5-HT6 receptor agonists is still under evaluation. However, both 5-HT6 antagonists and agonists seem to exert potential antidepressant activity. Recently, a second messenger system has been discovered. 5-HT6 receptor function is becoming more and more intriguing. Thus, the aim of the present book is to try to clarify the pharmacology of 5-HT6 receptors.

  • GABAb Receptor Pharmacology: A Tribute to Norman Bowery

    • 1st Edition
    • Volume 58
    • English
    This monograph was assembled to honor Professor Norman Bowery and his work on the 30th anniversary of his discovery of the GABAB receptor. In the present volume, leading neuroscientists from academia and industry provide a perspective of current research, both basic and translational, in the discovery of drugs acting at the GABAB receptor. The topics covered provide a comprehensive review of the field and the current state of research in this area. Included are chapters on the chemistry of GABAB agonists and antagonists, on the genetics and molecular composition of the site, its regulation and trafficking, and its role in controlling cellular, autonomic, and behavioral function. There are also chapters describing the potential clinical utility of drugs regulating GABAB activity receptor in the areas of hypertension, gastroesophageal reflux disease, Down syndrome, depression, and substance abuse. The information contained in this text will be of particular interest to neuroscientists in general and to neuropharmacologists in particular.

  • Nanoneuroscience and Nanoneuropharmacology

    • 1st Edition
    • Volume 180
    • Hari S. Sharma
    • English
    This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

  • Advances in Neuropharmacology

    • 1st Edition
    • Volume 85
    • Giacinto Bagetta + 3 more
    • English
    This volume provides a broad overview of important new advances in the field of Neuropharmacology. In 20 chapters, a selection of international contributors discuss topics including endocannabinoid function, pain, stress, astrocytes etc, and new possibilities for treatments of neurological diseases with neuropharmacological approaches.

  • Pharmacology

    Principles and Practice
    • 1st Edition
    • Miles Hacker + 2 more
    • English
    Pharmacology meets the rapidly emerging needs of programs training pharmacologic scientists seeking careers in basic research and drug discovery rather than such applied fields as pharmacy and medicine. While the market is crowded with many clinical and therapeutic pharmacology textbooks, the field of pharmacology is booming with the prospects of discovering new drugs, and virtually no extant textbook meets this need at the student level. The market is so bereft of such approaches that many pharmaceutical companies will adopt Hacker et al. to help train new drug researchers. The boom in pharmacology is driven by the recent decryption of the human genome and enormous progress in controlling genes and synthesizing proteins, making new and even custom drug design possible. This book makes use of these discoveries in presenting its topics, moving logically from drug receptors to the target molecules drug researchers seek, covering such modern topics along the way as side effects, drug resistance, pharmacogenomics, and even nutriceuticals, one in a string of culminating chapters on the drug discovery process. The book is aimed at advanced undergraduates and beginning graduate students in medical, pharmacy, and graduate schools looking for a solid introduction to the basic science of pharmacology and envisioning careers in drug research.

  • The Mouse Brain in Stereotaxic Coordinates, Compact

    The Coronal Plates and Diagrams
    • 3rd Edition
    • Keith B.J. Franklin + 1 more
    • English
    The Mouse Brain in Stereotaxic Coordinates is the most widely used and cited atlas of the mouse brain in print. It provides researchers and students with both accurate stereotaxic coordinates for laboratory use, and detailed delineations and indexing of structures for reference. The Compact 3rd edition is both a major revision and an expansion of previous compact editions. The 100 high resolution digital photographs of the coronal plane of section from the third full edition now complement the coronal drawings. The photographs of the sections and the intermediate sections are also provided on the accompanying CD. In addition, the compact version has a large introduction on stereotaxic surgery and the use of the atlas in the lab, as well as a number of panoramic simplified diagrams for student instruction. The Compact 3rd edition is in 8.5 x 11 format and is spiral bound suitable for positioning next to microscopes and cryotomes.

  • International Review of Neurobiology

    • 1st Edition
    • Volume 65
    • Ronald J. Bradley + 2 more
    • English
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

  • Chemical Factors in Neural Growth, Degeneration and Repair

    • 1st Edition
    • C. Bell
    • English
    This volume provides an up-to-date survey of current thinking concerning the actions of chemical factors in the regulation of neuronal behaviour under normal and pathological conditions. The book is divided into four sections, dealing with chemical factors involved with the formation of axon pathways, factors involved with neuronal survival and specialization during normal development, factors involved in normal maintenance and repair of adult neurons and, finally, factors that have been implicated as mediators of degenerative changes in neurological and neuropsychiatric disorders.

  • Neurotransmitter Receptors

    • 1st Edition
    • Volume 24
    • F. Hucho
    • English
    This comprehensive compilation provides a wealth of information on receptor sequences produced by recombinant DNA techniques used in combination with classical biochemistry. To minimize redundancies in this wealth of information, only a few receptors (some of which are typical for a whole group of similar receptors, others which are presently of special interest) are dealt with in a full-size chapter. Others are represented in the TIPS Receptor Nomenclature Supplement which is included as a special feature in this book, making this volume more useful as a receptor handbook.