Coronary Physiology in the Cardiac Cath Lab provides the foundational knowledge required to understand the concepts behind a variety of coronary physiologic assessments performed and required to apply them effectively when evaluating cardiac patients. Written to bring a practical and evidence-based approach, this book is a valuable resource for interventional and general cardiologists, cardiology researchers, physicians, cardiac catheterization laboratory staff, and anyone interested in understanding the theory and current practice surrounding assessing coronary physiology in the cardiac cath lab.Over the past decade, there has been an explosion of data validating the importance of assessing coronary physiology at the time of coronary angiography. This has led to the development of numerous new techniques and metrics for performing these assessments and also resulted in the inclusion of these indices into practice guidelines.
Human Reproduction: From Basics to Biotechnology is a complete reference for anyone in the field of life, health, and biomedical sciences. The book provides an overview of basics in human reproduction to advanced knowledge of the field, including some evidence from other mammalian species that complement our current knowledge on the anatomy and physiology of the male and female reproductive tract and gametes. This resource covers the most used assisted reproductive techniques and technical advances, human reproduction and infertility disorders, their diagnosis and available treatment options.
A Quick Reference to Obstetric Anesthesia is a comprehensive resource on the latest in anesthetic care for the pregnant patient. It covers the newest evidence on various critical topics in obstetric anesthesia, helping scientists identify opportunities for translational research. The inclusion of recommended perioperative protocols provides definitive references for optimal care. This book serves as an "in the moment" tool for solving challenging clinical problems, while functioning as a reference for both experienced clinicians and trainees. It also includes relevant patient management protocols, plus numerous emerging topics which are lacking in presently available texts.A Quick Reference to Obstetric Anesthesia is meant for anyone seeking immediately accessible research for real-time care of pregnant patients. Its approachable yet deep knowledge base will be appreciated by obstetric professionals at every level.
Insights into Migraine Treatments: Towards Personalized Medicine provides knowledge to facilitate the choice of optimal treatment for each patient in the context of migraine care. It presents the numerous therapies to treat migraines, and the methods by which they function. Further, this book discusses the challenges of determining which option is best for a particular patient. It offers key information on efficacy, safety, and biomarkers of patient responses to currently available therapies, thereby providing a resource to help healthcare professionals choose treatments tailored to individual patients. Researchers and clinicians alike will benefit from its solution-driven perspective.Insights into Migraine Treatments: Towards Personalized Medicine discusses topics ranging from pathophysiology of migraines to acute treatments, pharmacological and non-pharmacological preventive treatments, neuroimaging and neurophysiology, all with a view toward meeting the unique needs of each migraine patient.
Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes, Second Edition offers new discoveries in clinical settings, cellular, molecular, genetic, and epigenetic mechanisms which have led to novel understanding of the key role of endothelium in both cardiovascular and non-cardiovascular diseases. The innovations it presents have implications for both pathophysiological concepts and clinical decisions. Among other topics, cardiovascular and pulmonary medicine, immunity and inflammation, genetics and epigenetics, heart failure, renal disease, familial hypercholesterolemia, diabetes, and hypertension are discussed at length.With 20 new chapters covering everything from endothelium transition to connective tissue disorders, this second edition is sure to be indispensable to anyone wishing to learn the importance of endothelium to every facet of health.
New Opioid Receptor Modulators and Agonists: Relevance for Pain and Opioid Use Disorder Management provides crucial insights for developing ideal synthetic opioids. It discusses opioid receptor modulators’ structures and mechanisms, and their potential applications in treating pain, misuse, and addiction. This comprehensive resource delves into current research and therapeutic development avenues regarding opioid receptors' structure and function. Sections cover the rationale for developing allosteric modulators, identifying allosteric sites on opioid receptors, and the modulators' modes of action. Readers will gain a thorough understanding of creating ideal synthetic opioids and potential future research.It also explores pharmacogenomics, precision medicine, and various syndromes and comorbidities linked to opioid use. Lastly, it reviews novel synthetic opioids and the risks of misuse and overdose.
Pediatric Substance Exposure is a comprehensive resource designed to assist medical practitioners with long-term management of children and support of families affected by addictive substances during pregnancy. The book begins with coverage of epidemiology, global policy and practice, followed by a detailed review of various legal and illegal substances and the impact on the child. Subsequent chapters review fetal management, infant and child management, and social aspects and the family’s needs as the child grows. The book concludes with discussion of future research and policy needs. Clinicians as well as scientistic researchers will find value in this comprehensive guide on the management of pediatric patients at all stages of development exposed to substance use in utero. This book will aid in evidence-based decision making for optimal treatment of these children and support of the families affected by drug use during pregnancy.
Microglial Aging: Basic, Translational, and Clinical Advances covers the latest findings from basic, translational, and clinical research. The chapters review the physiological roles of microglia, the outcomes of aging on their structure and function, and their implication in age-related neurodegenerative diseases. Further, the book examines the effects of lifestyle that can potentiate beneficial microglial functions along the aging trajectory, thus preventing the onset of neurodegenerative diseases. Both pharmacological and non-pharmacological treatment strategies are discussed, including the ketogenic diet, cannabinoids, psychedelics, and non-invasive vagal nerve stimulation. With the demographically aging world population, increasing the quality of life and preventing age-related neurodegenerative diseases is currently of outmost importance. This book is a valuable resource for scientists and clinicians examining the impact of microglial health on aging.
Medications for Older Persons: Recommendations, Harms, Evidence provides a comprehensive resource detailing the benefits of medications for older individuals. It also addresses the potential harms associated with the prescription of potentially inappropriate medications or omissions in prescribing and examines how many adverse events, rehospitalizations, and deaths can be attributed to these medications. The book opens with a summary of medications that most benefit older patients, followed by the impact of older persons’ alcohol consumption, self-medication, and medication list accuracy and how these factors correlate to health outcomes.The remainder of the book is devoted to the assessment of medication groups focusing on Numbers Needed to Treat, Numbers Needed to Harm, and characteristics and numbers of adverse events. Medication groups covered include cardiovascular, central nervous system, renal, gastrointestinal, musculoskeletal, respiratory, endocrine, pain, and fall prevention.
Atlas of Endoscopy Imaging in Inflammatory Bowel Disease, Second Edition, serves as a comprehensive guide to the latest advancements in IBD. This new edition keeps readers updated with cutting-edge medical treatments, state-of-the-art endoscopy, and imaging technologies, as well as the evolution of interventional IBD. It explores the latest advancements in IBD diagnosis and management, including the most recent endoscopy instruments for measuring disease activity and the transformative world of image-enhanced endoscopy. Additionally, it delves into the groundbreaking application of Artificial Intelligence (AI) in IBD, revolutionizing diagnosis, disease monitoring, and dysplasia surveillance. New content introduces a range of topics to stay at the forefront of Inflammatory Bowel Disease (IBD) knowledge. These include Intestinal Ultrasound, Device-Associated Enteroscopy in Crohn’s Disease, insights into IBD-Like Conditions (Autoinflammatory Disorders), and the value of Intraoperative Endoscopy in IBD procedures. The book also integrates New Consensus Guidelines for Endoscopy Imaging in IBD, explores the Applications of Artificial Intelligence (AI) in IBD diagnosis and monitoring, addresses the intersection of COVID, COVID Vaccines, and IBD, and presents New Applications of Interventional IBD techniques. This second edition serves as a dynamic repository of state-of-the-art information, providing invaluable insights on differential diagnosis, advanced endoscopy, and imaging technologies, with a pronounced focus on AI. It also offers updated guidelines for disease activity assessment and the latest advancements in endoscopic therapy modalities. Designed to cater to a diverse range of medical professionals, it stands as an indispensable reference, fostering a comprehensive and up-to-date understanding of Inflammatory Bowel Disease (IBD). Within these pages,Gastroenterologists and IBD specialists will discover a wealth of resources to aid their pursuit of cutting-edge treatments and AI-driven insights. Primary care clinicians will find an expanded list of differential diagnoses that enables more accurate early-stage identification. Surgeons can elevate their expertise by delving into the intricacies of interventional IBD techniques, while pathologists and radiologists can enhance their diagnostic skills through AI and image-enhanced endoscopy. This comprehensive resource ensures that medical professionals across various disciplines are well-equipped to navigate the evolving landscape of IBD diagnosis, treatment, and management.