
Advancing Liver Transplantation
A Comprehensive Scientific Exploration of Machine Perfusion Techniques
- 1st Edition - June 1, 2026
- Editor: Andrea Schlegel
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 3 8 3 3 1 - 1
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 3 8 3 3 2 - 8
Advancing Liver Transplantation: A Foundational Exploration of Machine Perfusion Techniques lays the groundwork for understanding the intricate world of liver transp… Read more
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- Offers comprehensive guidance into the underlying mechanisms and practical aspects of machine perfusion, with a strong focus on clinical applications, equipping readers with valuable insights and practical skills
- Provides comprehensive content dedicated to the intricate field of machine perfusion in liver (and organ) transplantation, with pioneering insights and essential knowledge
- Features contributions from leading experts worldwide ensuring a comprehensive and unbiased approach to the content, offering diverse perspectives and cutting-edge research
1. History of liver preservation and machine perfusion
2. The role of machine perfusion in clinical practice: Why do we need it ?
Section 2. Different Types of Machine perfusion techniques in liver transplantation
3. Overview of different liver preservation techniques
4. Mechanism of ischemia-reperfusion injury and protective effects of machine perfusion
5. Normothermic regional perfusion
6. Normothermic machine perfusion
7. Hypothermic machine perfusion
8. Current combinations of different perfusion techniques
9. The role of machine perfusion for liver viability assessment
Section 3: Implementing machine perfusion in clinical practice
10. Establishing a clinical machine perfusion program
11. Impact of machine perfusion on healthcare economics
12. Balanced approach to the technological development of machine perfusion devices
Section 4: Innovations and emerging strategies
13. Prolonged Liver Preservation
14. Biomedical engineering and liver modulation
15. Other emerging liver preservation techniques
16. Future perspectives of liver preservation
- Edition: 1
- Published: June 1, 2026
- Language: English
AS
Andrea Schlegel
Dr. Andrea Schlegel is an academic transplant staff surgeon at the Cleveland Clinic specialized in abdominal transplantation with her own research group. Her treatment philosophy is based on a patient-centric and shared-decision making while incorporating the most recent innovative technologies as she helps patients through their liver transplant journey. Her research interests include experimental and clinical research with a focus on machine perfusion to improve the safe utilization of organs. Dr. Schlegel is an international expert in the field with over 150 publications in high-impact journals on a broad range of topics including underlying mechanisms of machine perfusion and ischemia - reperfusion injury and the development of new biomarkers to predict organ viability. Dr. Schlegel is an associated Editor and Reviewer in over 20 leading journals in the field and delivers over 30 invited lectures per year worldwide.