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Elsevier

Books in Medical biomaterials

  • Magnetic Nanoparticles in Nanomedicine

    • 1st Edition
    • Kai Wu + 1 more
    • English
    Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI).Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.

  • Advanced Technologies and Polymer Materials for Surgical Sutures

    • 1st Edition
    • Sabu Thomas + 4 more
    • English
    Polymeric materials offer a high level of versatility due to the range of applications possible within the biomedical and clinical fields – including wound closure - particularly in comparison to metals or ceramics. These specialised materials also allow for a diverse array of therapeutic effects. Although there have been advances in improving polymeric materials for surgical sutures, there is little information available regarding improving the therapeutic value of sutures, and advanced technologies used to implement this improvement. Advanced Technologies and Polymer Materials for Surgical Sutures provides thorough coverage on suture materials with improved mechanical and therapeutic properties that can improve quality of life; chapter topics include drug-releasing kinetics of sutures, shape memory polymer sutures and future trends.This book is a useful resource for academics and researchers in the materials science and biomedical engineering fields, as well as professionals in biomaterials and biotextiles development and clinicians looking to learn more about suture material properties and suture/body interactions.

  • Mechanical Behavior of Biomaterials

    • 1st Edition
    • J. Paulo Davim
    • English
    Mechanical Behaviour of Biomaterials focuses on the interface between engineering and medicine, where new insights into engineering aspects will prove to be extremely useful in their relation to the biomedical sciences and their applications. The book's main objective focuses on the mechanical behavior of biomaterials, covering key aspects, such as mechanical properties, characterization and performance. Particular emphasis is given to fatigue, creep and wear, fracture, and stress and strain relationships in biomaterials. Chapters look at both experimental and theoretical results. Readers will find this to be an essential reference for academics, biomechanical researchers, medical doctors, biologists, chemists, physicists, mechanical, biomedical and materials engineers and industrial professionals.

  • Mechanical Testing of Orthopaedic Implants

    • 1st Edition
    • Elizabeth Friis
    • English
    Mechanical Testing of Orthopaedic Implants provides readers with a thorough overview of the fundamentals of orthopedic implants and various methods of mechanical testing. Historical aspects are presented, along with case studies that are particularly useful for readers.

  • Orthodontic Applications of Biomaterials

    A Clinical Guide
    • 1st Edition
    • Theodore Eliades + 1 more
    • English
    Orthodontic Applications of Biomaterials: A Clinical Guide reviews the applications of biomaterials and their effects on enamel preparation, bonding, bracket and archwire ligation, mechanotherapy, debonding, and long-term enamel structural, color, and surface effects. The book provides a step-by-step analysis of the phenomena occurring, their clinical importance, and their underlying cause without the use of complex mathematical or physical-chemical analyses, with the goal of providing ‘digestible’ evidence for the clinician.

  • 3D Bioprinting

    Fundamentals, Principles and Applications
    • 1st Edition
    • Ibrahim Tarik Ozbolat
    • English
    3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives. Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics.

  • Metallic Foam Bone

    Processing, Modification and Characterization and Properties
    • 1st Edition
    • Cuie Wen
    • English
    Metallic Foam Bone: Processing, Modification and Characterization and Properties examines the use of porous metals as novel bone replacement materials. With a strong focus on materials science and clinical applications, the book also examines the modification of metals to ensure their biocompatibility and efficacy in vivo. Initial chapters discuss processing and production methods of metals for tissue engineering and biomedical applications that are followed by topics on practical applications in orthopedics and dentistry. Finally, the book addresses the surface science of metallic foam and how it can be tailored for medical applications. This book is a valuable resource for materials scientists, biomedical engineers, and clinicians with an interest in innovative biomaterials for orthopedic and bone restoration.

  • Monitoring and Evaluation of Biomaterials and their Performance In Vivo

    • 1st Edition
    • Roger Narayan
    • English
    Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials.

  • Material-Tissue Interfacial Phenomena

    Contributions from Dental and Craniofacial Reconstructions
    • 1st Edition
    • Paulette Spencer + 1 more
    • English
    Material-Tissue Interfacial Phenomena: Contributions from Dental and Craniofacial Reconstructions explores the material/tissue interfacial phenomena using dental and craniofacial reconstructions as a model system. As the mouth is a particularly caustic environment, the synthetic and/or bio-enabled materials used to repair damaged tissues and restore form, function, and esthetics to oral structures must resist a variety of physical, chemical, and mechanical challenges. These challenges are magnified at the interface between dissimilar structures such as the tooth/material interface. Interfacial reactions at the atomic, molecular, and nano-scales initiate the failure of materials used to repair, restore, and reconstruct dental and craniofacial tissues. Understanding the phenomena that lead to failure at the interface between dissimilar structures, such as synthetic materials and biologic tissues, is confounded by a variety of factors that are thoroughly discussed in this comprehensive book.

  • Medical Biosensors for Point of Care (POC) Applications

    • 1st Edition
    • Roger Narayan
    • English
    Medical Biosensors for Point of Care (POC) Applications discusses advances in this important and emerging field which has the potential to transform patient diagnosis and care. Part 1 covers the fundamentals of medical biosensors for point-of-care applications. Chapters in part 2 go on to look at materials and fabrication of medical biosensors while the next part looks at different technologies and operational techniques. The final set of chapters provide an overview of the current applications of this technology. Traditionally medical diagnostics have been dependent on sophisticated technologies which only trained professionals were able to operate. Recent research has focused on creating point-of-care diagnostic tools. These biosensors are miniaturised, portable, and are designed to be used at the point-of-care by untrained individuals, providing real-time and remote health monitoring.

  • In Situ Tissue Regeneration

    Host Cell Recruitment and Biomaterial Design
    • 1st Edition
    • Sang Jin Lee + 2 more
    • English
    In Situ Tissue Regeneration: Host Cell Recruitment and Biomaterial Design explores the body’s ability to mobilize endogenous stem cells to the site of injury and details the latest strategies developed for inducing and supporting the body’s own regenerating capacity. From the perspective of regenerative medicine and tissue engineering, this book describes the mechanism of host cell recruitment, cell sourcing, cellular and molecular roles in cell differentiation, navigational cues and niche signals, and a tissue-specific smart biomaterial system that can be applied to a wide range of therapies. The work is divided into four sections to provide a thorough overview and helpful hints for future discoveries: endogenous cell sources; biochemical and physical cues; smart biomaterial development; and applications.

  • Wound Healing Biomaterials - Volume 2

    Functional Biomaterials
    • 1st Edition
    • Magnus Ågren
    • English
    Wound Healing Biomaterials: Volume Two, Functional Biomaterials discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal wounds opening up a new area of research in biomaterials and the ways they can be applied to the challenges associated with wound care. Much research is now concerned with new therapies, regeneration methods, and the use of biomaterials that can assist in wound healing and alter healing responses. This book provides readers with a thorough review of the functional biomaterials used for wound healing, with chapters discussing the fundamentals of wound healing biomaterials, films for wound healing applications, polymer-based dressing for wound healing applications, and functional dressings for wound care.

  • Wound Healing Biomaterials - Volume 1

    Therapies and Regeneration
    • 1st Edition
    • Magnus Ågren
    • English
    Wound Healing Biomaterials: Volume One, Therapies and Regeneration discusses the types of wounds associated with trauma, illness, or surgery that can sometimes be extremely complex and difficult to heal. Consequently, there is a prominent drive for scientists and clinicians to find methods to heal these types of wounds, with science increasingly turning towards biomaterials to address these challenges. Much research is now concerned with new therapies, regeneration methods, and biomaterials to assist in wound healing and healing response. This book provides readers with a comprehensive review of the fundamentals and advances in the field of wound healing with regard to therapies and tissue regeneration. Chapters in Part One discuss fundamentals and strategies of wound healing, while Part Two reviews gene, stem cell, and drug delivery therapies for wound healing. Final chapters look at tissue regeneration strategies, making this an all-encompassing book on the topic of wound care and biomaterials.

  • Biomaterials and Regenerative Medicine in Ophthalmology

    • 2nd Edition
    • Traian Chirila + 1 more
    • English
    Biomaterials and Regenerative Medicine in Ophthalmology, Second Edition, focuses on an aging population and the increasing instances of eye diseases. Biomaterials continue to be used for numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. This book provides readers with an updated and expanded look at the present status and future direction of biomaterials and regenerative medicine in this important field.

  • Laser Surface Modification of Biomaterials

    Techniques and Applications
    • 1st Edition
    • Rui Vilar
    • English
    Laser Surface Modification of Biomaterials: Techniques and Applications covers this expanding field, which has many potential applications, including biomaterials. Laser surface modification of biomaterials enables the production of hybrid materials with different functionality in the bulk as well as the thin, sub-micrometer surface layer. This book will provide readers with a comprehensive review of the technology and its applications. Chapters in Part 1 look at the techniques and considerations of laser surface modification, while Part 2 reviews laser surface modification techniques of the most important classes of biomaterials, with a final set of chapters discussing application specific laser surface modification.

  • Nanobiomaterials in Medical Imaging

    Applications of Nanobiomaterials
    • 1st Edition
    • Alexandru Grumezescu
    • English
    Nanobiomaterials in Medical Imaging presents the latest developments in medical exploratory approaches using nanotechnology. Leading researchers from around the world discuss recent progress and state-of-the-art techniques. The book covers synthesis and surface modification of multimodal imaging agents, popular examples of nanoparticles and their applications in different imaging techniques, and combinatorial therapy for the development of multifunctional nanocarriers. The advantages and potential of current techniques are also considered. This book will be of interest to postdoctoral researchers, professors and students engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians.

  • Thin Film Coatings for Biomaterials and Biomedical Applications

    • 1st Edition
    • Hans J Griesser
    • English
    Thin Film Coatings for Biomaterials and Biomedical Applications discusses the latest information on coatings, including their historic use by scientists who are looking to improve the properties and biological responses of the material-host interface. Thin films, in particular, are becoming more widely researched and used as an alternative to traditional sprayed coatings because they have a more uniform structure and therefore greater stability. This book provides readers with a comprehensive guide to thin film coatings and their application in the biomaterials field. Part One of the book details the fundamentals of thin films for biomedical application, while Part Two looks at the special properties of thin films, with a final section reviewing functional thin films and their usage in biomedical applications.

  • Biomaterials Nanoarchitectonics

    • 1st Edition
    • Mitsuhiro Ebara
    • English
    Biomaterials Nanoarchitectonics, written from the perspectives of authors form NIMS and other researchers worldwide, provides readers with an explanation of the theory and techniques of nanoarchitectonics, exploring its applications in biomedical fields, including regenerative medicine, drug delivery, and diagnostic and treatment systems based on pathogenic mechanisms. The book also explains the use of nanomaterials that enable 'materials therapy', in which the materials themselves elicit a sustainable, curative effect from living tissue.

  • Medical Devices

    Regulations, Standards and Practices
    • 1st Edition
    • Seeram Ramakrishna + 4 more
    • English
    Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors’ practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards.

  • Functional Marine Biomaterials

    Properties and Applications
    • 1st Edition
    • Se-Kwon Kim
    • English
    Functional Marine Biomaterials: Properties and Applications provides readers with the latest information on the diverse marine environment as a resource for many new substances, including biopolymers, bioceramics, and biominerals. As recent advances and funding has enabled scientists to begin harnessing many of these materials for biomedical applications from drug delivery to bone tissue engineering and biosensors, this important new text provides readers with a comprehensive review of these materials and their functional applications in the biomedical field. Chapters discuss the properties of the main classes of functional marine biomaterials, applications of marine products in tissue engineering, applications in drug delivery systems, and the role of marine derived materials in medical devices.

  • Biomedical Textiles for Orthopaedic and Surgical Applications

    Fundamentals, Applications and Tissue Engineering
    • 1st Edition
    • Todd Blair
    • English
    Recent concerns over the possible effects of metal-on-metal orthopaedic implants and the evolution of more natural structures made from fibre have made medical device manufacturers consider the potential of fibre. Textiles offer the potential to replace traditional materials with novel fibres which are more suitable for many load bearing applications. Orthopaedics, in particular, is embracing textile technology for repairing, replacing, and regenerating integral pieces of the skeletal system and its associated components. This important new book will provide readers with a comprehensive overview of the role biomedical textiles can play in the orthopaedic field. Chapters in part one will discuss the fundamentals of textiles for orthopaedic applications. Part two will cover textiles for implantable orthopaedic applications whilst the final set of chapters will discuss the role of textiles in orthopaedic tissue engineering.

  • Surface Modification of Magnesium and its Alloys for Biomedical Applications

    Biological Interactions, Mechanical Properties and Testing
    • 1st Edition
    • T.S.N. Sankara Narayanan + 2 more
    • English
    Surface modification of magnesium and its alloys for biomedical applications: Biological interactions, mechanical properties and testing, the first of two volumes, is an essential guide on the use of magnesium as a degradable implant material. Due to their excellent biocompatibility and biodegradability, magnesium based degradable implants provide a viable option for the permanent metallic implants. This volume focuses on the fundamental concepts of surface modification of magnesium, its biological interactions, mechanical properties and, in vitro and in vivo testing. The contents of volume 1 is organized and presented in three parts. Part 1 reviews the fundamental aspects of surface modification of magnesium, including surface design, opportunities, challenges and its role in revolutionizing biodegradable biomaterials. Part 2 addresses the biological and mechanical properties covering an in vivo approach to the bioabsorbable behavior of magnesium alloys, mechanical integrity and, the effects of amino acids and proteins on the performance of surface modified magnesium. Part 3 delves in to testing and characterization, exploring the biocompatibility and effects on fatigue life alongside the primary characteristics of surface modified magnesium. All chapters are written by experts, this two volume series provides systematic and thorough coverage of all major modification technologies and coating types of magnesium and its alloys for biomedical applications.

  • Switchable and Responsive Surfaces and Materials for Biomedical Applications

    • 1st Edition
    • Johnathan Zhang
    • English
    Surface modification of biomaterials can ultimately determine whether a material is accepted or rejected from the human body, and a responsive surface can further make the material "smart" and "intelligent". Switchable and Responsive Surfaces and Materials for Biomedical Applications outlines synthetic and biological materials that are responsive under different stimuli, their surface design and modification techniques, and applicability in regenerative medicine/tissue engineering, drug delivery, medical devices, and biomedical diagnostics. Part one provides a detailed overview of switchable and responsive materials and surfaces, exploring thermo-responsive polymers, environmentally responsive polyelectrolytes and zwitterionic polymers, as well as peptide-based and photonic sensitive switchable materials. Further chapters include a detailed overview of the preparation and analysis of switchable polymer brushes and copolymers for biomedical application. Part two explores the biological interactions and biomedical applications of switchable surfaces, where expert analysis is provided on the interaction of switchable surfaces with proteins and cells. The interaction of stimuli-sensitive polymers for tissue engineering and drug delivery with biosurfaces is critiqued, whilst the editor provides a skillful study into the application of responsive polymers in implantable medical devices and biosensors.

  • Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy

    • 1st Edition
    • Gang Ho Lee + 1 more
    • English
    Most books discuss general and broad topics regarding molecular imagings. However, Ultrasmall Lanthanide Oxide Nanoparticles for Biomedical Imaging and Therapy, will mainly focus on lanthanide oxide nanoparticles for molecular imaging and therapeutics. Multi-modal imaging capabilities will discussed, along with up-converting FI by using lanthanide oxide nanoparticles. The synthesis will cover polyol synthesis of lanthanide oxide nanoparticles, Surface coatings with biocompatible and hydrophilic ligands will be discussed and TEM images and dynamic light scattering (DLS) patterns will be provided. Various techniques which are generally used in analyzing the synthesized surface coated nanoparticles will be explored and this section will also cover FT­, IR analysis, XRD analysis, SQUID analysis, cytotoxicity measurements and proton relaxivity measurements. In vivo MR images, CT images, fluorescence images will be provided and Therapeutic application of gadolinium oxide nanoparticles will be discussed. Finally, future perpectives will be discussed. That is, present status and future works needed for clinical applications of lanthanide oxide nanoparticles to molecular imagings will be discussed.

  • Regulatory Affairs for Biomaterials and Medical Devices

    • 1st Edition
    • Stephen F. Amato + 1 more
    • English
    All biomaterials and medical devices are subject to a long list of regulatory practises and policies which must be adhered to in order to receive clearance. This book provides readers with information on the systems in place in the USA and the rest of the world. Chapters focus on a series of procedures and policies including topics such as commercialization, clinical development, general good practise manufacturing and post market surveillance.

  • Biomaterials for Bone Regeneration

    Novel Techniques and Applications
    • 1st Edition
    • P. Dubruel + 1 more
    • English
    Novel Biomaterials for Bone Regeneration provides a comprehensive review of currently available biomaterials and how they can be applied in bone regeneration. In recent decades, there has been a shift from the idea of using biomaterials as passive substitutes for damaged bones towards the concept of biomaterials as aids for the regeneration of a host's own bone tissue. This has generated an important field of research and a range of technological developments. Part one of this book discusses a wide range of materials, including calcium phosphate cements, hydrogels, biopolymers, synthetic polymers, and shape memory polymers. Part two then turns to the processing and surface modification of biomaterials, as well as how biomaterials can be evaluated both for their mechanical properties and for immunocompatibility with the host. Finally, part three covers a variety of cellular approaches, and production and delivery of biomaterials for bone regeneration. Chapters also consider the potential of electromagnetic and ultrasonic stimulation of biomaterials to aid in the regenerative process. Novel Biomaterials for Bone Regeneration represents an important resource for academics, clinicians, and industry professionals working in the area of biomedical materials, providing them with both an overview of the current state-of-the-art, and an indication of potential future developments.

  • Silk Biomaterials for Tissue Engineering and Regenerative Medicine

    • 1st Edition
    • Subhas C. Kundu
    • English
    Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area. Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering. Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering.

  • Microfluidic Devices for Biomedical Applications

    • 1st Edition
    • Xiujun (James) Li + 1 more
    • English
    Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications.The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis.Microfluid... devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries.

  • Advanced Ceramics for Dentistry

    • 1st Edition
    • James Shen
    • English
    The growth of implant and fixed prosthodontics practices in dentistry has created a rapidly increasing demand for advanced ceramics and ceramic processes. Innovations in ceramics and ceramic processes are vital to ensure reliable and affordable dental-restoration solutions with aesthetically pleasing outcomes. The work aims to engage the bioceramics and engineering communities to meet the challenges of modern dental restoration using advanced ceramics. Incorporating fundamental science, advanced engineering concepts, and clinical outcomes, the work is suitable for bioceramicists, ceramics manufacturers, dental clinicians and biologists.

  • Biomaterials and Medical Tribology

    Research and Development
    • 1st Edition
    • J. Paulo Davim + 1 more
    • English
    Medical tribology can be defined as the science of tribological phenomena in the human body, both those that naturally occur in the tissues or organs and those that arise after implantation of an artificial device, while biomaterials are inert substances designed to be incorporated into living systems. Biomaterials and medical tribology brings together a collection of high quality articles and case studies focussing on new research and developments in these two important fields.The book provides details of the different types of biomaterial available and their applications, including nanoparticles for biomedical applications, synergism effects during fiction and fretting corrosion experiments, application of biomedical-grade titanium alloys in trabecular bone and artificial joints, fatigue strengthening of an orthopaedic Ti6AI4V alloy, wear determination on retrieved metal-on-metal hip arthoplasty, natural articular joints, the importance of bearing porosity in engineering and natural lubrication, tribological characterization of human tooth enamel, and finally, liposome-based carrier systems and devices used for pulmonary drug delivery.Biomaterial... and medical tribology is an essential reference for materials scientists, engineers, and researchers in the field of medical tribology. The title also provides an overview for academics and clinicians in this area.

  • Biocompatibility and Performance of Medical Devices

    • 1st Edition
    • Jean-Pierre Boutrand
    • English
    Implant and device manufacturers are increasingly facing the challenge of proving that their products are safe and biocompatible, and that they will perform as expected. Biocompatibility and performance of medical devices provides an essential guide to the performance analysis of these vital devices.Part one introduces the key concepts and challenges faced in relation to biocompatibility in medical devices, with consideration of biological safety evaluation planning and biomechanical and biochemical compatibility in innovative biomaterials. Part two goes on to discuss the evaluation and characterisation of biocompatibility in medical devices. Topics covered include material and chemical characterisation, allowable limits for toxic leachables, in vivo and in vitro testing and blood compatibility assessment. Testing and interpreting medical device performance is the focus of part three, with chapters describing preclinical performance studies for bone, dental and soft tissue implants, and mechanical testing of soft and hard tissue implants. Part four provides information on the regulation of medical devices in the European Union, Japan and China, and the book concludes with part five, a review of histopathology principles for biocompatibility and performance studies.With its distinguished editor and international team of expert contributors, Biocompatibility and performance of medical devices is a vital tool for all those involved in the research, design, production and application of medical devices, including research directors, production companies and medical regulatory agencies, as well as industry professionals and academics.

  • Biomaterials Science

    An Introduction to Materials in Medicine
    • 3rd Edition
    • Buddy D. Ratner + 3 more
    • English
    The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.

  • Durability and Reliability of Medical Polymers

    • 1st Edition
    • Mike Jenkins + 1 more
    • English
    Given the widespread use of polymers in medical devices, the durability and reliability of this material in use is an area of critical importance. Durability and reliability of medical polymers reviews the performance of both bioresorbable and non-bioresorbable medical polymers.Part one provides a review of the types and properties of bioresorbable medical polymers. The effect of molecular structure on properties is discussed, along with the processing of bioresorbable and other polymers for medical applications. Transport phenomena and the degradation of bioresorbable medical polymers are reviewed, before an exploration of synthetic bioresorbable polymers and their use in orthopaedic tissue regeneration. Part two goes on to explore the durability and reliability of non-bioresorbable medical polymers, and wear processes in polymer implants and ageing processes of biomedical polymers in the body are discussed in depth, before an investigation into manufacturing defects and the failure of synthetic polymeric medical devices.With its distinguished editors and international team of expert contributors, Durability and reliability of medical polymers is an essential tool for all materials scientists, researchers and engineers involved in the design, development and application of medical polymers, whilst also providing a helpful overview of the subject for biologists, chemist and clinicians.

  • Coatings for Biomedical Applications

    • 1st Edition
    • Mike Driver
    • English
    The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications.The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices.With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings.

  • Handbook of Medical Textiles

    • 1st Edition
    • V Bartels
    • English
    With a rising population and the increasing range of textiles for medical products, the need to understand and improve medical textiles is gaining in importance. The Handbook of medical textiles provides an overview of the different types of medical textiles currently available as well as specific information on more specialised topics and applications.In part one, the types and properties of medical textiles are discussed, with chapters covering topics including reusable textiles, textiles for implants and textiles with cosmetic effects. Part two focuses on the interaction of textiles with the skin, examining key issues such as contact sensations, allergies and mechanical irritation. Chapters in part three provide information on the latest developments in textiles for hygiene and infection control, while part four provides a range of applications and case studies, including improvements in medical occupational clothing, medical filters and superabsorbent fibres.With its expert editor and contributions from some of the world’s leading authorities, the Handbook of medical textiles is a standard reference for designers and manufacturers of medical textile products, as well as for biomaterials scientists and medical professionals.

  • Functional Textiles for Improved Performance, Protection and Health

    • 1st Edition
    • N Pan + 1 more
    • English
    The textile industry is increasingly based on ongoing innovation and development of higher performance products, and the field of functional textiles is no exception. This book explores the development of textiles with a wide range of functions, with the aim of improving the performance of the product in terms of the protection and health benefits that it can offer.The book is split into two parts. Part one focuses on functional textiles for improved performance and protection, with chapters reviewing antistatic, flame retardant and infrared functional textiles, among many others. Chapters in part two examine the uses of functional textiles in a medical context, including superhydrophobic materials, antibacterial textiles and insect-repellent materials.With its distinguished editors and contributions from some of the world’s leading authorities, Functional textiles for improved performance, protection and health is invaluable for textile scientists, technologists and engineers as well as those designing and manufacturing textiles. It is also a suitable reference for the academic sector.

  • Advanced Wound Repair Therapies

    • 1st Edition
    • David Farrar
    • English
    Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds.Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices.With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject.

  • Preprosthetic and Maxillofacial Surgery

    Biomaterials, Bone Grafting and Tissue Engineering
    • 1st Edition
    • J Ferri + 1 more
    • English
    One of the most important factors in ensuring successful osseointegration is the stability of the implant after its insertion. In order to achieve optimum conditions for implantation, it is often necessary to prepare the area and reconstruct the bone to ensure that it is the correct shape and size for the implant. Preprosthetic and maxillofacial surgery provides a thorough review of the current status and future direction of this important field. Part one reviews bone grafting for implantology and reconstructive preprosthetic surgery. Chapters in part two discuss reconstruction and rehabilitation whilst the final group of chapters analyse tissue engineering applications.

  • Biomedical Hydrogels

    Biochemistry, Manufacture and Medical Applications
    • 1st Edition
    • Steve Rimmer
    • English
    Hydrogels are very important for biomedical applications because they can be chemically manipulated to alter and control the hydrogel’s interaction with cells and tissues. Their flexibility and high water content is similar to that of natural tissue, making them extremely suitable for biomaterials applications. Biomedical hydrogels explores the diverse range and use of hydrogels, focusing on processing methods and novel applications in the field of implants and prostheses. Part one of this book concentrates on the processing of hydrogels, covering hydrogel swelling behaviour, superabsorbent cellulose-based hydrogels and regulation of novel hydrogel products, as well as chapters focusing on the structure and properties of hydrogels and different fabrication technologies. Part two covers existing and novel applications of hydrogels, including chapters on spinal disc and cartilage replacement implants, hydrogels for ophthalmic prostheses and hydrogels for wound healing applications. The role of hydrogels in imaging implants in situ is also discussed. With its distinguished editor and international team of contributors, Biomedical hydrogels is an excellent reference for biomedical research scientists and engineers in industry and academia, as well as others involved in research in this area, such as research clinicians.

  • Injectable Biomaterials

    Science and Applications
    • 1st Edition
    • Brent Vernon
    • English
    Novel injectable materials for non-invasive surgical procedures are becoming increasingly popular. An advantage of these materials include easy deliverability into the body, however the suitability of their mechanical properties must also be carefully considered. Injectable biomaterials covers the materials, properties and biomedical applications of injectable materials, as well as novel developments in the technology.Part one focuses on materials and properties, with chapters covering the design of injectable biomaterials as well as their rheological properties and the mechanical properties of injectable polymers and composites. Part two covers the clinical applications of injectable biomaterials, including chapters on drug delivery, tissue engineering and orthopaedic applications as well as injectable materials for gene delivery systems. In part three, existing and developing technologies are discussed. Chapters in this part cover such topics as environmentally responsive biomaterials, injectable nanotechnology, injectable biodegradable materials and biocompatibility. There are also chapters focusing on troubleshooting and potential future applications of injectable biomaterials.With its distinguished editor and international team of contributors, Injectable biomaterials is a standard reference for materials scientists and researchers working in the biomaterials industry, as well as those with an academic interest in the subject. It will also be beneficial to clinicians.

  • Surface Modification of Biomaterials

    Methods Analysis and Applications
    • 1st Edition
    • Rachel Williams
    • English
    The surface modification of biomaterials plays a significant role in determining the outcome of biological-material interactions. With the appropriate modification a material’s surface can be tailored to improve biocompatibility, adhesion and cell interactions. Consequently surface modification is vital in the development and design of new biomaterials and medical devices. Surface modification of biomaterials reviews both established surface modifications and those still in the early stages of research and discusses how they can be used to optimise biological interactions and enhance clinical performance.Part one begins with chapters looking at various types and techniques of surface modification including plasma polymerisation, covalent binding of poly (ethylene glycol) (PEG), heparinisation, peptide functionalisation and calcium phosphate deposition before going on to examine metal surface oxidation and biomaterial surface topography to control cellular response with particular reference to technologies, cell behaviour and biomedical applications. Part two studies the analytical techniques and applications of surface modification with chapters on analysing biomaterial surface chemistry, surface structure, morphology and topography before moving onto discuss modifying biomaterial surfaces to optimise interactions with blood, control infection, optimise interactions with soft tissues, repair and regenerate nerve cells, control stem cell growth and differentiation and to optimise interactions with bone.The distinguished editor and international team of contributors to Surface modification of biomaterials have produced a unique overview and detailed chapters on a range of surface modification techniques which will provide an excellent resource for biomaterials researchers and scientists and engineers concerned with improving the properties of biomaterials. It will also be beneficial for academics researching surface modification.

  • Biomaterials and Devices for the Circulatory System

    • 1st Edition
    • Terence Gourlay + 1 more
    • English
    Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods.Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry.Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering.With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field.

  • Biointegration of Medical Implant Materials

    Science and Design
    • 1st Edition
    • Chandra P. Sharma
    • English
    Biointegration is essential for the successful performance of implanted materials and devices within the human body. With an increasing number and wide range of implant procedures being performed, it is critical that materials scientists and engineers effectively design implant materials which will create a positive biological and mechanical response with the host tissue.Biointegratio... of medical implant materials provides a unique and comprehensive review of recent techniques and research into material and tissue interaction and integration. Part one discusses soft tissue biointegration with chapters on the biocompatibility of engineered stem cells, corneal tissue engineering and vascular grafts. Part two then reviews particular techniques in drug delivery including inorganic nanoparticles for targeted drug delivery and alginate based drug delivery devices. Part three covers design considerations with coverage of themes such as biocompatibility of materials and its relevance to drug delivery and tissue engineering, mechanisms of failure of medical implants during long term use and rapid prototyping in biomedical engineering.With its distinguished editor and team of international contributors, Biointegration of medical implant materials: science and design is a standard reference for medical materials scientists and engineers in industry and the academic sector.

  • Biomaterials and Regenerative Medicine in Ophthalmology

    • 1st Edition
    • Traian Chirila + 1 more
    • English
    With an increasingly aged population, eye diseases are becoming more widespread. Biomaterials have contributed in recent years to numerous medical devices for the restoration of eyesight, improving many patients’ quality of life. Consequently, biomaterials and regenerative medicine are becoming increasingly important to the advances of ophthalmology and optometry. Biomaterials and regenerative medicine in ophthalmology reviews the present status and future direction of biomaterials and regenerative medicine in this important field.Part one discusses applications in the anterior segment of the eye with chapters on such topics as advances in intraocular lenses (IOLs), synthetic corneal implants, contact lenses, and tissue engineering of the lens. Part two then reviews applications in the posterior segment of the eye with such chapters on designing hydrogels as vitreous substitutes, retinal repair and regeneration and the development of tissue engineered membranes. Chapters in Part three discuss other pertinent topics such as hydrogel sealants for wound repair in ophthalmic surgery, orbital enucleation implants and polymeric materials for orbital reconstruction.With its distinguished editor and international team of contributors, Biomaterials and regenerative medicine in ophthalmology is a standard reference for scientists and clinicians, as well as all those concerned with this ophthalmology.

  • Biomaterials for Treating Skin Loss

    • 1st Edition
    • D P Orgill + 1 more
    • English
    The primary causes of wounds requiring skin replacement are severe burns and ulcers. Materials must provide an effective temporary barrier, promote healing and minimise scarring. Massive improvements have been made to skin repair biomaterials in the last ten years with widespread adoption of new developments in the medical sector. This book provides a comprehensive review of the range of biomaterials for treating skin loss.Part one discusses the basics of skin replacement with chapters on such topics as markets and regulation, biomechanics and the biological environment of skin. Part two then reviews epidermal and dermal replacement technology with chapters on such topics as alternative delivery of keratinocytes, collagen-based and human origin-based dermal replacement, and lyophilized xenogenic products. The final section explores combined dermis and epidermal replacement technologies and provides a round-up of skin replacement principles.With its distinguished editors and international team of contributors, Biomaterials for treating skin loss is a standard reference for those researching skin replacement technologies, particularly those interested in treating burns and ulcers.

  • Orthopaedic Bone Cements

    • 1st Edition
    • S Deb
    • English
    Bone cements are widely used in orthopaedic applications to anchor implants to existing bone, reconstruct bone and deliver bioactive agents to the body. With an increasing number of bone cements available, it is vital that the correct material is selected for specific clinical procedures. Orthopaedic bone cements reviews the most recent research in this field.Part one discusses the current uses of orthopaedic bone cements with chapters on such topics as hip replacements, verteboplasty and wear particles and osteolysis. Part two reviews materials and types of cement such as acrylic, polymethylmethacryla... and calcium phosphate cements. Chapters in Part three address the mechanical properties of bone cements such as fracture toughness and dynamic creep. The final section examines methods to enhance the properties of bone cements with coverage of themes such as antibiotic loaded bone cements and bioactive cements.With its eminent editor and multidisciplinary team of international contributors, Orthopaedic bone cements is an invaluable reference for materials scientists, medical researchers and all those involved in the development of bone cements for orthopaedic applications and joint replacement.

  • Biomedical Polymers

    • 1st Edition
    • Mike Jenkins
    • English
    Given the rapid development and use of biomaterials, it is becoming increasingly important to understand the structure, processing and properties of biomedical polymers and their medical applications. With its distinguished editor and team of international contributors, Biomedical Polymers reviews the latest research on this important group of biomaterials.The book discusses natural, synthetic, biodegradable and non bio-degradable polymers and their applications. Chapters review polymeric scaffolds for tissue engineering and drug delivery systems, the use of polymers in cell encapsulation, their role as replacement materials for heart valves and arteries, and their applications in joint replacement. The book also discusses the use of polymers in biosensor applications.Biomedi... polymers is an essential reference for scientists and all those concerned with the development and use of this important group of biomaterials

  • Bioscience and Bioengineering of Titanium Materials

    • 1st Edition
    • Yoshiki Oshida
    • English
    This unique book about bioscience and the bioengineering of titanium materials is based on more than 1,000 published articles. It bridges the gap between the medical/dental fields and the engineering/technolo... areas, due to the author’s unique experience in both during the last 30 years. The book covers Materials Classifications, Chemical and Electrochemical Reactions, Oxidation, Biological Reactions, Implant-related Biological Reactions, Applications, Fabri-cation Technologies, Surface Modifications, and Future Perspectives.

  • Medical Textiles and Biomaterials for Healthcare

    • 1st Edition
    • Subhash C. Anand + 3 more
    • English
    Medical textiles are a major growth area within the technical textiles industry and the range of applications continues to grow and increase in diversity with every new development. Recent innovations include novel chitosan-alginate fibres for advanced wound dressings, ultrasonic energy for bleaching cotton medical textiles, durable and rechargeable biocidal textiles, spider silk supportive matrix for cartilage regeneration, barbed bi-directional surgical sutures and intelligent textiles for medical applications.Medical textiles and biomaterials for healthcare is a culmination of the worldwide research into medical textiles and biomaterials. It is divided into eight parts covering the main areas of basic biomaterials, healthcare and hygiene products, infection control and barrier materials, bandaging and pressure garments, woundcare materials, implantable and medical devices and smart technologies. Each part contains a comprehensive overview written by leading experts in the area. The overviews are then followed by a selection of the best papers from the 2003 MEDTEX Conference, hosted by the University of Bolton. It has been extensively edited to produce what is expected to be the leading reference on this subject.

  • Advances in Chemical Engineering

    Molecular and Cellular Foundations of Biomaterials
    • 1st Edition
    • Volume 29
    • Michael J Sefton
    • English
    This latest volume in the Advances in Chemical Engineering series, is a contemporary analysis of the preparation, structure and properties of biomaterials with emphasis on the molecular design and material/polymer interactions. The book addresses cell-biomaterials adhesion, biomaterials and gene therapy, protein adsorption, platelet and white cell activation processes, molecular design and surface modification of novel biomaterials.