Magnetic Nanoparticles in Nanomedicine provides readers with the fundamental theories and principles of magnetic materials, the synthesis and surface functionalization strategies of MNPs, and the standard techniques for characterizing physicochemical properties of MNPs. Other sections review MNP-based therapies such as magnetic hyperthermia therapy, drug/gene delivery, and magnetic neurostimulation and cover MNP-based in vitro and in vivo disease diagnosis, respectively, including techniques such as magnetoresistive (MR), nuclear magnetic resonance (NMR), magnetic particle spectroscopy (MPS) biosensing platforms, magnetic resonance imaging (MRI), and magnetic particle imaging (MPI).Final chapters address biocompatibility and safety issues in applying MNPs to in vivo biomedical applications, including coverage of the toxicity of MNPs to human tissues, the immune responses of the human body to these particles, as well as blood circulation time of MNPs.
Polymeric materials offer a high level of versatility due to the range of applications possible within the biomedical and clinical fields – including wound closure - particularly in comparison to metals or ceramics. These specialised materials also allow for a diverse array of therapeutic effects. Although there have been advances in improving polymeric materials for surgical sutures, there is little information available regarding improving the therapeutic value of sutures, and advanced technologies used to implement this improvement. Advanced Technologies and Polymer Materials for Surgical Sutures provides thorough coverage on suture materials with improved mechanical and therapeutic properties that can improve quality of life; chapter topics include drug-releasing kinetics of sutures, shape memory polymer sutures and future trends.This book is a useful resource for academics and researchers in the materials science and biomedical engineering fields, as well as professionals in biomaterials and biotextiles development and clinicians looking to learn more about suture material properties and suture/body interactions.
Mechanical Behaviour of Biomaterials focuses on the interface between engineering and medicine, where new insights into engineering aspects will prove to be extremely useful in their relation to the biomedical sciences and their applications. The book's main objective focuses on the mechanical behavior of biomaterials, covering key aspects, such as mechanical properties, characterization and performance. Particular emphasis is given to fatigue, creep and wear, fracture, and stress and strain relationships in biomaterials. Chapters look at both experimental and theoretical results. Readers will find this to be an essential reference for academics, biomechanical researchers, medical doctors, biologists, chemists, physicists, mechanical, biomedical and materials engineers and industrial professionals.
Mechanical Testing of Orthopaedic Implants provides readers with a thorough overview of the fundamentals of orthopedic implants and various methods of mechanical testing. Historical aspects are presented, along with case studies that are particularly useful for readers.
Orthodontic Applications of Biomaterials: A Clinical Guide reviews the applications of biomaterials and their effects on enamel preparation, bonding, bracket and archwire ligation, mechanotherapy, debonding, and long-term enamel structural, color, and surface effects. The book provides a step-by-step analysis of the phenomena occurring, their clinical importance, and their underlying cause without the use of complex mathematical or physical-chemical analyses, with the goal of providing ‘digestible’ evidence for the clinician.
3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives. Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics.
Metallic Foam Bone: Processing, Modification and Characterization and Properties examines the use of porous metals as novel bone replacement materials. With a strong focus on materials science and clinical applications, the book also examines the modification of metals to ensure their biocompatibility and efficacy in vivo. Initial chapters discuss processing and production methods of metals for tissue engineering and biomedical applications that are followed by topics on practical applications in orthopedics and dentistry. Finally, the book addresses the surface science of metallic foam and how it can be tailored for medical applications. This book is a valuable resource for materials scientists, biomedical engineers, and clinicians with an interest in innovative biomaterials for orthopedic and bone restoration.
Monitoring and Evaluation of Biomaterials and Their Performance In Vivo provides essential information for scientists and researchers who need to assess and evaluate performance, monitor biological responses, gauge efficacy, and observe changes over time. Crucially, it also enables the optimization of design for future biomaterials and implants. This book presents readers with comprehensive coverage of the topic of in vivo monitoring of medical implants and biomaterials.
Material-Tissue Interfacial Phenomena: Contributions from Dental and Craniofacial Reconstructions explores the material/tissue interfacial phenomena using dental and craniofacial reconstructions as a model system. As the mouth is a particularly caustic environment, the synthetic and/or bio-enabled materials used to repair damaged tissues and restore form, function, and esthetics to oral structures must resist a variety of physical, chemical, and mechanical challenges. These challenges are magnified at the interface between dissimilar structures such as the tooth/material interface. Interfacial reactions at the atomic, molecular, and nano-scales initiate the failure of materials used to repair, restore, and reconstruct dental and craniofacial tissues. Understanding the phenomena that lead to failure at the interface between dissimilar structures, such as synthetic materials and biologic tissues, is confounded by a variety of factors that are thoroughly discussed in this comprehensive book.
Science and Principles of Biodegradable and Bioresorbable Medical Polymers: Materials and Properties provides a practical guide to the use of biodegradable and bioresorbable polymers for study, research, and applications within medicine. Fundamentals of the basic principles and science behind the use of biodegradable polymers in advanced research and in medical and pharmaceutical applications are presented, as are important new concepts and principles covering materials, properties, and computer modeling, providing the reader with useful tools that will aid their own research, product design, and development. Supported by practical application examples, the scope and contents of the book provide researchers with an important reference and knowledge-based educational and training aid on the basics and fundamentals of these important medical polymers.