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3D Bioprinting

Fundamentals, Principles and Applications

  • 1st Edition - November 21, 2016
  • Latest edition
  • Author: Ibrahim Tarik Ozbolat
  • Language: English

3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains… Read more

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Description

3D Bioprinting: Fundamentals, Principles and Applications provides the latest information on the fundamentals, principles, physics, and applications of 3D bioprinting. It contains descriptions of the various bioprinting processes and technologies used in additive biomanufacturing of tissue constructs, tissues, and organs using living cells. The increasing availability and decreasing costs of 3D printing technologies are driving its use to meet medical needs, and this book provides an overview of these technologies and their integration. Each chapter discusses current limitations on the relevant technology, giving future perspectives.

Professor Ozbolat has pulled together expertise from the fields of bioprinting, tissue engineering, tissue fabrication, and 3D printing in his inclusive table of contents. Topics covered include raw materials, processes, machine technology, products, applications, and limitations. The information in this book will help bioengineers, tissue and manufacturing engineers, and medical doctors understand the features of each bioprinting process, as well as bioink and bioprinter types. In addition, the book presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics.

Key features

  • Describes all aspects of the bioprinting process, from bioink processing through design for bioprinting, bioprinting techniques, bioprinter technologies, organ printing, applications, and future trends
  • Provides a detailed description of each bioprinting technique with an in-depth understanding of its process modeling, underlying physics and characteristics, suitable bioink and cell types printed, and major accomplishments achieved thus far
  • Explains organ printing technology in detail with a step-by-step roadmap for the 3D bioprinting of organs from isolating stem cells to the post-transplantation of organs
  • Presents tactics that can be used to select the appropriate process for a given application, such as tissue engineering and regenerative medicine, transplantation, clinics, or pharmaceutics

Readership

Professionals, students, and researchers in biomedical engineering, tissue engineering, manufacturing engineering, industrial engineering, and the medical and 3D printing industries

Table of contents

1. Introduction1.1 Tissue Engineering1.2 Three-Dimensional Printing in Tissue Engineering1.3 Three-Dimensional Bioprinting1.4 The Organization of the Book1.5 SummaryReferences2. Design for Bioprinting2.1 Introduction2.2 Design Requirements for Three-Dimensional Bioprinting2.3 Medical Imaging2.4 Blueprint Modeling2.5 Toolpath Planning for Bioprinting2.6 Limitations2.7 Future Directions2.8 SummaryReferencesFurther Reading3. The Bioink3.1 Introduction3.2 Bioink Materials3.3 Comparative Evaluation of Bioink Materials3.4 Limitations3.5 Future Directions3.6 SummaryReferences4. Extrusion-Based Bioprinting4.1 Introduction4.2 Extrusion-Based Bioprinting4.3 Process Configurations4.4 Comparison of Extrusion-Based Bioprinting With Other Bioprinting Techniques4.5 Limitations4.6 Future Directions4.7 SummaryReferencesFurther Reading5. Droplet-Based Bioprinting5.1 Introduction5.2 Inkjet Bioprinting5.3 Electrohydrodynamic Jet Bioprinting5.4 Acoustic Bioprinting5.5 Microvalve Bioprinting5.6 Droplet-Substrate Interactions5.7 Biomaterials Used in Droplet-Based Bioprinting5.8 Comparison of Droplet-Based Bioprinting With Other Bioprinting Techniques5.9 Recent Achievements in Droplet-Based Bioprinting5.10 Limitations5.11 Future Directions5.12 SummaryReferences6. Laser-Based Bioprinting6.1 Introduction6.2 Modalities of Laser-Based Bioprinting6.3 Toward Multimaterial Bioprinting6.4 Comparison of Laser-Based Bioprinting With Other Bioprinting Modalities6.5 Recent Achievements in Laser-Based Bioprinting6.6 Limitations6.7 Future Directions6.8 SummaryReferences7. Bioprinter Technologies7.1 Introduction7.2 Bioprinters7.3 Limitations7.4 Future Directions7.5 SummaryReferencesFurther Reading8. Roadmap to Organ Printing8.1 Introduction8.2 State-of-the-Art in Organ Printing8.3 Roadmap to Organ Printing8.4 Limitations8.5 Future Directions8.6 SummaryReferences9. Applications of 3D Bioprinting9.1 Introduction9.2 Tissue Engineering and Regenerative Medicine9.3 Transplantation and Clinics9.4 Drug Screening and High-Throughput Assays9.5 Cancer Research9.6 Limitations9.7 Future Directions9.8 SummaryReferences10. Future Trends10.1 Introduction 10.2 Innovative Developments in Bioprinting Technology and Its Components10.3 Toward Four-Dimensional Bioprinting10.4 Toward Functional Organ Fabrication10.5 From In Vitro to In Situ: Translation of Bioprinting Technologies Into Operating Rooms10.6 Bioprinting New Types of Organs10.7 Bioprinting Deoxyribonucleic Acid for Controlled Gene Therapy10.8 Regulatory Issues10.9 SummaryReferences

Product details

  • Edition: 1
  • Latest edition
  • Published: November 24, 2016
  • Language: English

About the author

IO

Ibrahim Tarik Ozbolat

Dr. Ibrahim T. Ozbolat is a Professor of Engineering Science and Mechanics Department, Biomedical Engineering Department, and Neurosurgery Department and a faculty member of the Huck Institutes of the Life Sciences, Materials Research Institute, and Center for Neural Engineering at Penn State. Dr. Ozbolat’s major research is in the areas of bioprinting and tissue engineering. His research has been widely published, received various awards, and has been featured in national and international media and press numerous times. He has delivered over 100 invited talks and keynotes at national and international forums and conferences. His technology spun off two start-up companies and he is an advisory board member for multiple leading companies in bioprinting.
Affiliations and expertise
Associate Professor, Dept. of Engineering Science and Mechanics, The Huck Institutes of the Life Sciences, Penn State University, University Park, USA

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