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Elsevier

Books in Bioengineering and manufacturing

  • Innovations and Human Factors Challenges in Healthcare Product Design

    • 1st Edition
    • Kamalpreet Sandhu + 3 more
    • English
    Innovations and Human Factors Challenges in Healthcare Product Design covers best practices and advanced design methods to capture, document, and validate various challenges at the early stage of the design process, also delving into how to mitigate design strategies to address those challenges without compromising the cost, effort, safety, and quality of the device. The book provides a comprehensive collection of technical notes, research designs, design methods and processes, case studies, comprehensive literature on the industrial impact of design methods and processes, and applications of digital technologies for design, analysis, manufacturing, testing, and deployment. Readers will find multidisciplinary coverage of the application of technology and science for product design in healthcare sectors.

  • Advances in 3D and 4D Printing of Medical Robots and Devices

    • 1st Edition
    • Ankit Sharma + 1 more
    • English
    Advances in 3D and 4D Printing of Medical Robots and Devices presents the most recent innovative breakthroughs in smart manufacturing and biomedical engineering to help enhance knowledge and expertise in 3D/4D printing technologies and advancements in biomedical applications through robotics and medical devices. This book highlights the usage and importance of 3D/4D printing-based prototyping as well as the manufacturing of robotic elements such as energy generators, morphology control, and novel design strategies. This book will help readers to pursue contemporary insights into currently ongoing practices in biomedical and mechatronic engineering including the fabrication of actuators manufacturing; muscles, vibration dampers, bio-inspired structures, pre-surgical and post-surgical tooling, medical assistance robots, drug delivery, microfluidic, and wearable electronics. Academic scholars, manufacturing scientists, and commercial manufacturers of bio-devices and medical robotics will find this book to be useful in adopting competent biomaterials as well as innovative techniques for applications in biomedical engineering.

  • Effect of High-Pressure Technologies on Enzymes

    Science and Applications
    • 1st Edition
    • Bruno Ricardo de Castro Leite Júnior + 1 more
    • English
    Effect of High-Pressure Technologies on Enzyme: Science and Applications provides a deep, practical discussion of high-pressure processing (HPP) and high-pressure homogenization (HPH) technologies and biochemical approaches, applied across research and industry, with applications ranging from food to pharmaceuticals and commercial enzyme production. Early chapters discuss foundational aspects of HPP and HPH approaches; the science of enzyme modification; and basic aspects of enzyme activity, stability, and structure as studied in biochemical processes. Later chapters consider the effect of HPP and HPH technologies and their mechanisms of controlling enzyme modification to improve enzyme performance for chosen applications. Special attention is paid to the application of HPP and HPH technologies and enzyme modifications in food processing, microbial enzyme modification, drug discovery, and production of other commercial enzymes, as well as the challenges of undesirable enzyme inactivation. The final chapter discusses future directions of the field and technologies, and expanded applications.

  • Biotechnology for Beginners

    • 3rd Edition
    • Reinhard Renneberg
    • English
    Biotechnology for Beginners, Third Edition presents the latest developments in the evolving field of biotechnology which has grown to such an extent over the past few years that increasing numbers of professional’s work in areas that are directly impacted by the science. This book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy and animal science. This book will also appeals to lay readers who do not have a scientific background but are interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Loroch discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome.

  • Modern Practical Healthcare Issues in Biomedical Instrumentation

    • 1st Edition
    • Dilber Uzun Ozsahin + 1 more
    • English
    Modern Practical Healthcare Issues in Biomedical Instrumentation describes the designs, applications and principles of several medical devices used in hospitals and at home. The book presents practical devices that can potentially be used for healthcare purposes. Sections cover the use of biosensors to monitor the physiological properties of the human body, focusing on devices used to evaluate, measure and manipulate the biological system, and highlighting practical devices that can potentially be used for healthcare purposes. It is an excellent resource for undergraduate, graduate and post-graduate students of biomedical engineering.

  • Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms

    • 1st Edition
    • Xinyu Liu + 1 more
    • English
    Micro and Nano Systems for Biophysical Studies of Cells and Small Organisms provides a comprehensive introduction to the state-of-the-art micro and nano systems that have recently been developed and applied to biophysical studies of cells and small organisms. These micro and nano systems span from microelectromechanic... systems (MEMS) and microfluidic devices to robotic micro-nanomanipulati... systems. These biophysical studies range from cell mechanics to the neural science of worms and Drosophila. This book will help readers understand the fundamentals surrounding the development of these tools and teach them the most recent advances in cellular and organismal biophysics enabled by these technologies.

  • Autonomous Robot-Aided Optical Manipulation for Biological Cells

    • 1st Edition
    • Mingyang Xie
    • English
    Autonomous Robot-Aided Optical Manipulation for Biological Cells gives a systematically and almost self-contained description of the many facets of modeling, sensing, and control techniques or experimentally exploring emerging trends in optical manipulation of biological cell in micro/nanorobotics systems. To achieve biomedical applications, reliability design, modeling, and precision control are vitally important for the development of engineering systems. With the advances in modeling, sensing, and control techniques, it is opportunistic to exploit them for the benefit of reliability design, actuation, and precision control of micro/nanomanipulati... systems to expanding the applications of robot at the micro and nano scales, especially in biomedical engineering. This book presents new techniques in reliability modeling and advanced control of robot-aided optical manipulation of biological cells systems. The book will be beneficial to the researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts.

  • 3D Printing in Medicine and Surgery

    Applications in Healthcare
    • 1st Edition
    • Daniel J. Thomas + 1 more
    • English
    3D Printing in Medicine and Surgery: Applications in Healthcare is an advanced book on surgical and enhanced medical applications that can be achieved with 3D printing. It is an essential handbook for medical practitioners, giving access to a range of practical methods, while also focusing on applied knowledge. This comprehensive resource features practical experiments and processes for preparing 3D printable materials. Early chapters cover foundational knowledge and background reading, while later chapters discuss and review the current technologies used to engineer specific tissue types, experiments and methods, medical approaches and the challenges that lie ahead for future research. The book is an indispensable reference guide to the various methods used by current medical practitioners working at the forefront of 3D printing applications in medicine.

  • Intelligence-Based Medicine

    Artificial Intelligence and Human Cognition in Clinical Medicine and Healthcare
    • 1st Edition
    • Anthony C. Chang
    • English
    Intelligence-Based Medicine: Data Science, Artificial Intelligence, and Human Cognition in Clinical Medicine and Healthcare provides a multidisciplinary and comprehensive survey of artificial intelligence concepts and methodologies with real life applications in healthcare and medicine. Authored by a senior physician-data scientist, the book presents an intellectual and academic interface between the medical and the data science domains that is symmetric and balanced.The content consists of basic concepts of artificial intelligence and its real-life applications in a myriad of medical areas as well as medical and surgical subspecialties. It brings section summaries to emphasize key concepts delineated in each section; mini-topics authored by world-renowned experts in the respective key areas for their personal perspective; and a compendium of practical resources, such as glossary, references, best articles, and top companies.The goal of the book is to inspire clinicians to embrace the artificial intelligence methodologies as well as to educate data scientists about the medical ecosystem, in order to create a transformational paradigm for healthcare and medicine by using this emerging new technology.

  • Lignocellulosics

    Renewable Feedstock for (Tailored) Functional Materials and Nanotechnology
    • 1st Edition
    • Ilari Filpponen + 2 more
    • English
    Lignocellulosics: Renewable Feedstock for (Tailored) Functional Materials and Nanotechnology gives a comprehensive overview of recent advances in using lignocellulosic substrates in materials science and nanotechnology. The functionalization and processing of lignocellulosics are described via a number of examples that cover films, gels, sensors, pharmaceutics and energy storage. In addition to the research related to functional cellulose nanomaterials, there has been an increased interest in research on lignin and lignocellulosics. This book explains how utilizing biomaterials as a raw material allows ambitious reconstruction of smart materials that are green and multifunctional. As lignin as a valuable material has gained a lot of attention in the last few years, shifting from purely extraction and fundamental characterization, and now also focusing on the preparation of exciting materials, such as nanoparticles, readers will find this to be a comprehensive resource on the topic.

  • Measuring Capacity to Care Using Nursing Data

    • 1st Edition
    • Evelyn J.S. Hovenga AM + 1 more
    • English
    Measuring Capacity to Care Using Nursing Data presents evidence-based solutions regarding the adoption of safe staffing principles and the optimum use of operational data to enable health service delivery strategies that result in improved patient and organizational outcomes. Readers will learn how to make better use of informatics to collect, share, link and process data collected operationally for the purpose of providing real-time information to decision- makers. The book discusses topics such as dynamic health care environments, health care operational inefficiencies and costly events, how to measure nursing care demand, nursing models of care, data quality and governance, and big data. The content of the book is a valuable source for graduate students in informatics, nurses, nursing managers and several members involved in health care who are interested in learning more about the beneficial use of informatics for improving their services.

  • Pan-genomics: Applications, Challenges, and Future Prospects

    • 1st Edition
    • Debmalya Barh + 3 more
    • English
    Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches,” brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics,” thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics”, encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health.

  • Engineering Strategies for Regenerative Medicine

    • 1st Edition
    • Tiago G. Fernandes + 2 more
    • English
    Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development.

  • Data for Nurses

    Understanding and Using Data to Optimize Care Delivery in Hospitals and Health Systems
    • 1st Edition
    • Molly McNett
    • English
    Data for Nurses: Understanding and Using Data to Optimize Care Delivery in Hospitals and Health Systems provides information for nurses on how to work with data to effectively evaluate and improve care delivery for patients. Quality, benchmarking, and research data are increasingly used to guide care in hospitals and health systems, and nurses are expected to actively use this information to identify interventions to optimize outcomes and meet reporting and financial targets. However, not all nurses receive formal training on data utilization, making interpretation and application of the different types of data difficult. This book provides information on topics such as benchmarking and reportable indicators, financial metrics, quality improvement, research, and implementation science, with applications to nursing practice. Important information on protective measures to guarantee integrity and security of personal patient data is also included. The book is a valuable resource for nurses and other healthcare professionals who require a basic understanding of key principles of data utilization in order to increase engagement in evidence-based practices, quality improvement, and mandatory reporting of key indices.

  • Data Processing Handbook for Complex Biological Data Sources

    • 1st Edition
    • Gauri Misra
    • English
    Data Processing Handbook for Complex Biological Data provides relevant and to the point content for those who need to understand the different types of biological data and the techniques to process and interpret them. The book includes feedback the editor received from students studying at both undergraduate and graduate levels, and from her peers. In order to succeed in data processing for biological data sources, it is necessary to master the type of data and general methods and tools for modern data processing. For instance, many labs follow the path of interdisciplinary studies and get their data validated by several methods. Researchers at those labs may not perform all the techniques themselves, but either in collaboration or through outsourcing, they make use of a range of them, because, in the absence of cross validation using different techniques, the chances for acceptance of an article for publication in high profile journals is weakened.

  • EEG Brain Signal Classification for Epileptic Seizure Disorder Detection

    • 1st Edition
    • Sandeep Kumar Satapathy + 3 more
    • English
    EEG Brain Signal Classification for Epileptic Seizure Disorder Detection provides the knowledge necessary to classify EEG brain signals to detect epileptic seizures using machine learning techniques. Chapters present an overview of machine learning techniques and the tools available, discuss previous studies, present empirical studies on the performance of the NN and SVM classifiers, discuss RBF neural networks trained with an improved PSO algorithm for epilepsy identification, and cover ABC algorithm optimized RBFNN for classification of EEG signal. Final chapter present future developments in the field. This book is a valuable source for bioinformaticians, medical doctors and other members of the biomedical field who need the most recent and promising automated techniques for EEG classification.

  • Nanomaterials for Biosensors

    Fundamentals and Applications
    • 1st Edition
    • Bansi D. Malhotra + 1 more
    • English
    Nanomaterials for Biosensors: Fundamentals and Applications provides a detailed summary of the main nanomaterials used in biosensing and their application. It covers recent developments in nanomaterials for the fabrication of biosensor devices for healthcare diagnostics, food freshness and bioprocessing. The various processes used for synthesis and characterization of nanostructured materials are examined, along with the design and fabrication of bioelectronic devices using nanostructured materials as building blocks. Users will find the fundamentals of the main nanomaterials used in biosensing, helping them visualize a systematic and coherent picture of how nanomaterials are used in biosensors. The book also addresses the role of bio-conjugation of nanomaterials in the construction of nano-biointerfaces for application in biosensors. Such applications, including metal nanoparticles, metal oxide nanoparticles, nanocomposites, carbon nanotubes, conducting polymers and plasmonic nanostructures in biosensing are discussed relative to each nanomaterial concerned. Finally, recent advancements in protein functionalized nanomaterials for cancer diagnostics and bio-imaging are also included.

  • Algal Green Chemistry

    Recent Progress in Biotechnology
    • 1st Edition
    • Rajesh Prasad Rastogi + 2 more
    • English
    Algal Green Chemistry: Recent Progress in Biotechnology presents emerging information on green algal technology for the production of diverse chemicals, metabolites, and other products of commercial value. This book describes and emphasizes the emerging information on green algal technology, with a special emphasis on the production of diverse chemicals, metabolites, and products from algae and cyanobacteria. Topics featured in the book are exceedingly valuable for researchers and scientists in the field of algal green chemistry, with many not covered in current academic studies. It is a unique source of information for scientists, researchers, and biotechnologists who are looking for the development of new technologies in bioremediation, eco-friendly and alternative biofuels, biofertilizers, biogenic biocides, bioplastics, cosmeceuticals, sunscreens, antibiotics, anti-aging, and an array of other biotechnologically important chemicals for human life and their contiguous environment. This book is a great asset for students, researchers, and biotechnologists.

  • Glycerol

    The Renewable Platform Chemical
    • 1st Edition
    • Mario Pagliaro
    • English
    Glycerol: The Renewable Platform Chemical provides a valuable overview of the glycerol market, including industrial applications and sustainable production of glycerol. Replacing previous works on the subject, this useful resource describes glycerol, also known as glycerine, and its chemical derivatives, especially the new bioglycerol-derived products. The monograph also discusses how the industrial use of glycerol as raw material for producing commodity chemicals depends on broader scope and lower cost of the catalytic process used to convert glycerol of varying purity grades into valued monomers. New chapters on glycerol polymers, the use of glycerol as antifreeze, and its sustainable production offer relevant information for researchers and professionals from academics and industry alike. The book features new processes, such as low cost and biocompatible glycerol polymers as a major alternative to the conventional polymers, with the first practical applications now emerging in the biomedical and patient care markets. The book offers both a source of inspiration for new projects and a reliable source of information on how glycerol is replacing petrochemicals in many real world applications.

  • Bioprinting

    Techniques and Risks for Regenerative Medicine
    • 1st Edition
    • Maika G. Mitchell
    • English
    Innovation is added value to a known process. Bioprinting: Techniques and Risks for Regenerative Medicine aims to stimulate a scientifically grounded, interdisciplinary, multiscale debate and exchange of ideas using the techniques described in the book. 3D printing and additive manufacturing evolved from within the field of Cell Biology will have the ability to recreate cells queried from large amounts of phenotypic and molecular data. Stem Cell biologists, biotechnologists and material engineers, as well as graduate students will greatly benefit from the practical knowledge and case examples provided throughout this book.

  • Biotechnology for Beginners

    • 2nd Edition
    • Reinhard Renneberg + 1 more
    • English
    Biotechnology for Beginners, Second Edition, presents the latest information and developments from the field of biotechnology—the applied science of using living organisms and their by-products for commercial development—which has grown and evolved to such an extent over the past few years that increasing numbers of professionals work in areas that are directly impacted by the science. For the first time, this book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy, and animal science. This book also appeals to the lay reader without a scientific background who is interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Demain discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome. This stimulating book is the most user-friendly source for a comprehensive overview of this complex field.

  • Current Developments in Biotechnology and Bioengineering

    Production, Isolation and Purification of Industrial Products
    • 1st Edition
    • Ashok Pandey + 2 more
    • English
    Current Developments in Biotechnology and Bioengineering: Production, Isolation and Purification of Industrial Products provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, focusing on industrial biotechnology and bioengineering practices for the production of industrial products, such as enzymes, organic acids, biopolymers, and biosurfactants, and the processes for isolating and purifying them from a production medium. During the last few years, the tools of molecular biology and genetic and metabolic engineering have rendered tremendous improvements in the production of industrial products by fermentation. Structured by industrial product classifications, this book provides an overview of the current practice, status, and future potential for the production of these agents, along with reviews of the industrial scenario relating to their production.

  • Current Developments in Biotechnology and Bioengineering

    Solid Waste Management
    • 1st Edition
    • Jonathan W-C Wong + 2 more
    • English
    Current Developments in Biotechnology and Bioengineering: Solid Waste Management provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, reviewing the latest innovative developments in environmental biotechnology and bioengineering as they pertain to solid wastes, also revealing current research priority areas in solid waste treatment and management. The fate of solid wastes can be divided into three major areas, recycling, energy recovery, and safe disposal. From this foundation, the book covers such key areas as biotechnological production of value added products from solid waste, bioenergy production from various organic solid wastes, and biotechnological solutions for safe, environmentally-frie... treatment and disposal. The state of the art situation, potential advantages, and limitations are discussed, along with proposed strategies on how to overcome limitations.

  • Current Developments in Biotechnology and Bioengineering

    Crop Modification, Nutrition, and Food Production
    • 1st Edition
    • Suresh Kumar Dubey + 2 more
    • English
    Current Developments in Biotechnology and Bioengineering: Crop Modification, Nutrition, and Food Production provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends, presenting data-based scientific knowledge on agribiotechnology and describing world agriculture and the role biotechnology can play in ensuring food security over the next fifty years. The book discusses the effects of climate change in agriculture and the resultant emergence of new crops, including drought tolerant and more nutritious plants. In addition, the book discusses insect and virus resistance in plants and outlines plant metabolic engineering for agriculture, genetically engineered plants, and microbial diseases.

  • Current Developments in Biotechnology and Bioengineering

    Foundations of Biotechnology and Bioengineering
    • 1st Edition
    • Ashok Pandey + 1 more
    • English
    Current Developments in Biotechnology and Bioengineering: Foundations of Biotechnology and Bioengineering is a package of nine books that compile the latest ideas from across the entire arena of biotechnology and bioengineering. This volume focuses on the underlying principles of biochemistry, microbiology, fermentation technology, and chemical engineering as interdisciplinary themes, constructing the foundation of biotechnology and bioengineering.

  • Current Developments in Biotechnology and Bioengineering

    Food and Beverages Industry
    • 1st Edition
    • Ashok Pandey + 4 more
    • English
    Current Developments in Biotechnology and Bioengineering: Food and Beverages Industry provides extensive coverage of new developments, state-of-the-art technologies, and potential future trends compiled from the latest ideas across the entire arena of biotechnology and bioengineering. This volume reviews current developments in the application of food biotechnology and engineering for food and beverage production. As there have been significant advances in the areas of food fermentation, processing, and beverage production, this title highlights the advances in specific transformation processes, including those used for alcoholic beverage and fermented food production. Taking a food process and engineering point-of-view, the book also aims to select important bioengineering principles, highlighting how they can be quantitatively applied in the food and beverages industry.

  • Platform Chemical Biorefinery

    Future Green Chemistry
    • 1st Edition
    • Satinder Kaur Brar + 2 more
    • English
    Platform Chemical Biorefinery: Future Green Chemistry provides information on three different aspects of platform chemical biorefinery. The book first presents a basic introduction to the industry beneficial for university students, then provides engineering details of existing or potential platform chemical biorefinery processes helpful to technical staff of biorefineries. Finally, the book presents a critical review of the entire platform chemical biorefinery process, including extensive global biorefinery practices and their potential environmental and market-related consequences. Platform chemicals are building blocks of different valuable chemicals. The book evaluates the possibility of renewable feedstock-based platform chemical production and the fundamental challenges associated with this objective. Thus, the book is a useful reference for both academic readers and industry technical workers. The book guides the research community working in the field of platform chemical biorefinery to develop new pathways and technologies in combination with their market value and desirability.

  • Engineering of Nanobiomaterials

    Applications of Nanobiomaterials
    • 1st Edition
    • Alexandru Grumezescu
    • English
    Engineering of Nanobiomaterials presents the most recent information regarding the specific modifications of nanomaterials and of their synthesis methods, in order to obtain particular structures for different biomedical purposes. This book enables the results of current research to reach those who wish to use this knowledge in an applied setting. Engineered nanobiomaterials, designed from organic or inorganic raw materials, offer promising alternatives in many biomedical applications. In this book, eminent researchers from around the world discuss the various applications, including antibacterial therapy, biosensors, cancer therapy, stimuli-responsive drug release, drug delivery, gene therapy and visual prostheses. In each case, advantages, drawbacks and future potential are outlined. This book will be of interest to students, postdoctoral researchers and professors engaged in the fields of materials science, biotechnology and applied chemistry. It will also be highly valuable to those working in industry, including pharmaceutics and biotechnology companies, medical researchers, biomedical engineers and advanced clinicians.

  • Biomimetic Technologies

    Principles and Applications
    • 1st Edition
    • Trung Dung Ngo
    • English
    Biomimetic engineering takes the principles of biological organisms and copies, mimics or adapts these in the design and development of new materials and technologies. Biomimetic Technologies reviews the key materials and processes involved in this groundbreaking field, supporting theoretical background by outlining a range of applications. Beginning with an overview of the key principles and materials associated with biomimetic technologies in Part One, the book goes on to explore biomimetic sensors in more detail in Part Two, with bio-inspired tactile, hair-based, gas-sensing and sonar systems all reviewed. Biomimetic actuators are then the focus of Part Three, with vision systems, tissue growth and muscles all discussed. Finally, a wide range of applications are investigated in Part Four, where biomimetic technology and artificial intelligence are reviewed for such uses as bio-inspired climbing robots and multi-robot systems, microrobots with CMOS IC neural networks locomotion control, central pattern generators (CPG’s) and biologically inspired antenna arrays.

  • Ultrafiltration for Bioprocessing

    • 1st Edition
    • Herbert Lutz
    • English
    Ultrafiltration for Bioprocessing is key reading for all those involved in the biotechnology and biopharmaceutical areas. Written by a leading worker in the area, it includes many practical applications and case studies in the key process of ultrafiltration (UF), which is used in almost every bioprocess.

  • Biomechanics and Related Bio-Engineering Topics

    Proceedings of a Symposium Held in Glasgow, September 1964
    • 1st Edition
    • R. M. Kenedi
    • English

  • High Technology Aids for the Disabled

    • 1st Edition
    • W.J. Perkins
    • English
    High Technology Aids for the Disabled presents some technical aids and microcomputers for the disabled. This technology could herald a major advance in improving the quality of life of many disabled people. Organized into four parts, this book begins with an assessment of disability. This book then presents a very wide variety of bioengineering approaches to replacement of function. Subsequent chapters explore the reduction of handicap using computer technology, following three main themes: microcomputer systems, user input controls, and speech training and recognition. The last part discusses the collaboration with user organizations in the development of technological aids. This book will be useful for disabled people in coping with their respective difficulties and for those people involved in helping disabled people maximize their human potential.

  • Modelling and Control of Biotechnical Processes

    Proceedings of the First IFAC Workshop, Helsinki, Finland, August 17-19, 1982
    • 1st Edition
    • A. Halme
    • English
    Modeling and Control of Biotechnical Processes covers the proceedings of the First International Federation of Automatic Control Workshop by the same title, held in Helsinki, Finland on August 17-19, 1982. This book is organized into seven sections encompassing 37 chapters. The opening section deals with the measurement techniques in fermentation processes and the use of automated analyzers to control microbial processes. The next sections consider the concepts of bioreactor modeling and related problems, as well as the modeling and control of biological wastewater treatment processes. Other sections discuss the economic and static optimization, the computer control of production processes, and the application of estimation and identification methods to biotechnological processes. The final sections explore the principles of real-time analysis, use of computer control in specific biotechnical production, process control design, and the modeling of adaptive control. This book is of great value to biotechnologists, biochemists, and control engineers.

  • Advances in Biomedical Engineering

    Published Under the Auspices of the Biomedical Engineering Society
    • 1st Edition
    • J. H. U. Brown + 1 more
    • English
    Advances in Biomedical Engineering, Volume 2, is a collection of papers that discusses the basic sciences, the applied sciences of engineering, the medical sciences, and the delivery of health services. One paper discusses the models of adrenal cortical control, including the secretion and metabolism of cortisol (the controlled process), as well as the initiation and modulation of secretion of ACTH (the controller). Another paper discusses hospital computer systems—application problems, objective evaluation of technology, and multiple pathways for future hospital computer applications. The possible information paths of an orthotic or prosthetic systems using computing ability include the following components: signal sources, transducers, signal processors, output systems, feedback receptors, and local feedback. Ultrasound energy is a powerful diagnostic tool since it is nondestructive and has asertainability characteristics. The medical technician or researcher can also use gas-phase analytical instruments and analytical systems in investigative chemical methods involving microgram, nanogram or pictogram amounts of individual organic compounds. The collection is suitable for biochemists, microbiologists, bio-engineers, and investigators whose works involve biomedical engineering and physiological research.

  • Stem Cell Bioprocessing

    For Cellular Therapy, Diagnostics and Drug Development
    • 1st Edition
    • Tiago G. Fernandes + 2 more
    • English
    Stem cell bioprocessing describes the main large-scale bioprocessing strategies for both stem cell culture and purification, envisaging the application of these cells for regenerative medicine and drug screening. Bioreactor configurations are described, including their applications for stem cell expansion, and stem cell separation techniques such as isolation and purification are discussed. Basic definitions are provided concerning the different types of stem cells, from adult stem cells to the more recent induced pluripotent stem cells. The main characteristics of these different stem cell types are described, alongside the molecular mechanisms underlying their self-renewal and differentiation. The book also focuses on methodologies currently used for in vitro stem cell culture under static conditions, including the challenge of xeno-free culture conditions, as well as culture parameters that influence stem cell culture. Approaches for both stem cell culture and separation in micro-scale conditions are presented, including the use of cellular microarrays for high-throughput screening of the effect of both soluble and extracellular matrix molecules. A further section is dedicated to application of stem cells for regenerative medicine.

  • Lean Biomanufacturing

    Creating Value through Innovative Bioprocessing Approaches
    • 1st Edition
    • Nigel J Smart
    • English
    With decreasing profit margins, increasing cost pressures, growing regulatory compliance concerns, mounting pressure from generic drugs and increasing anxiety about the future of healthcare reimbursement, pharmaceutical manufacturers are now forced to re-examine and re-assess the way they have been doing things. In order to sustain profitability, these companies are looking to reduce waste (of all kinds), improve efficiency and increase productivity. Many of them are taking a closer look at lean manufacturing as a way to achieve these goals. Lean biomanufacturing re-visits lean principles and then applies them sympathetically - in a highly practical approach - to the specific needs of pharmaceutical processes, which present significantly different challenges to more mainstream manufacturing processes. A major goal of the book is to highlight those problems and issues that appear more specific or unique to biopharmaceutical manufacturing situations and to provide some insights into what challenges are the important ones to solve and what techniques, tools and mechanisms to employ to be successful.Following an introduction to lean biomanufacturing, the book goes on to discuss lean technologies and methods applied in biomanufacturing. Later chapters cover the creation and implementation of the Transition Plan, issues facing the biopharmaceutical industry, creating a lean approach towards biopharmaceutical processes and the contribution of simulation models in developing these processes. The final chapter covers examples of new technology innovations which help facilitate lean biomanufacturing.

  • Bioscience and Bioengineering of Titanium Materials

    • 2nd Edition
    • Yoshiki Oshida
    • English
    The second edition of Bioscience and Bioengineering of Titanium Materials is an essential resource for anyone researching titanium in its fundamental aspects and in medical/dental applications. The book organizes and processes the findings from over 2,000 published articles and studies into a coherent and easily accessible volume, deftly weaving together older and newer technologies to give a clear overview. Bridging the gap between medical/dental and engineering/technolo... areas, the book covers material classification, fabrication and modification, as well as applications and biological reactions to titanium implants. The author, with extensive work in academics and industry, helps medical practitioners and students answer many practical questions, including: What is titanium? What type of titanium materials should I use in this case? How can I fabricate my design using titanium? Are there any alternative materials or methods? In the second edition, macro-, micro-, and nano-texturing of titanium surfaces, tissue engineering-related materials including scaffolds, and functionally graded materials and structures are extensively included and analyzed.

  • Biology and the Manufacturing Industries

    Proceedings of Symposium held at the Royal Geographical Society, London on 29 and 30 September 1966
    • 1st Edition
    • M Brook
    • English
    Biology and the Manufacturing Industries focuses on the appreciation of the role of biology in the operations of manufacturing industries. Divided into four parts with 18 chapters, the book contains the literature of various authors who have diligently conducted studies on the relationship of biology and the manufacturing industries. The discussions start with the industrial aspects of microbial food production, particularly focusing on the symba-yeast process, pest control, and the factors affecting continuous fermentation. The book also notes the impact of manufacturing industries on agriculture. The book considers the importance of biological factors to the design and operation of power stations, as well as the biological processes in the treatment and disposal of waste waters. This topic includes actions to be taken regarding microbiological problems as well as the conduct of research sponsored by the manufacturing industries. The discussions progresses to how sensory methods can solve flavor problems in the food industry. The toxicity of potential drugs is also given importance. Lastly, the role of biologists in the industries, as well as their role as industrial engineers, is emphasized. The book is a must for readers who are interested in exploring the role of biology in the manufacturing industries and other fields.

  • Therapeutic Antibody Engineering

    Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry
    • 1st Edition
    • William R Strohl + 1 more
    • English
    The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.

  • The Design and Manufacture of Medical Devices

    • 1st Edition
    • J. Paulo Davim + 1 more
    • English
    Medical devices play an important role in the field of medical and health technology, and encompass a wide range of health care products. Directive 2007/47/EC defines a medical device as any instrument, apparatus, appliance, software, material or other article, whether used alone or in combination, including the software intended by its manufacturer to be used specifically for diagnostic and/or therapeutic purposes and necessary for its proper application, intended by the manufacturer to be used for human beings. The design and manufacture of medical devices brings together a range of articles and case studies dealing with medical device R&D. Chapters in the book cover materials used in medical implants, such as Titanium Oxide, polyurethane, and advanced polymers; devices for specific applications such as spinal and craniofacial implants, and other issues related to medical devices, such as precision machining and integrated telemedicine systems.

  • Adverse Effects of Engineered Nanomaterials

    Exposure, Toxicology, and Impact on Human Health
    • 1st Edition
    • Bengt Fadeel + 2 more
    • English
    Adverse Effects of Engineered Nanoparticles: A Disease-Oriented Approach provides a systematic evaluation of representative engineered nanomaterial (ENM) of high volume production and of high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies and the general public need to know about nanosafety. This book, written by leading international experts in nanotoxicology and nanmoedicine, gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers and patients. The beneficial applications, both diagnostic and therapeutic, of ENM are also highlighted. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, and the clinical and pathological consequences of such exposure in the human population.

  • Advances in Textile Biotechnology

    • 1st Edition
    • V Nierstrasz + 1 more
    • English
    Biotechnology has impacted the textiles industry through the development of more efficient and environmentally friendly manufacturing processes, as well as enabling the design of improved textile materials. This book will provide a thorough overview of current and future focuses of biotechnology in the fibre and textile industry. Part one of the book opens with a review of technologies involved in textile biotechnology. Chapters explore the design and engineering of novel enzymes for textile applications and developments in processes and equipment for enzymatic textile treatments. Part two investigates the modification of particular fibres through the use of biotechnology. Key topics include the treatment of wool and silk fibres and the enzymatic treatment versus conventional processing of cotton.With expert contributions from leaders in their fields, Advances in textile biotechnology is a comprehensive guide for those in the textile and fibre industry, as well as experts in the biology, chemical and environmental engineering industries.

  • Handbook of Textile Fibre Structure

    Volume 2: Natural, Regenerated, inorganic and Specialist Fibres
    • 1st Edition
    • Stephen Eichhorn + 3 more
    • English
    Due to their complexity and diversity, understanding the structure of textile fibres is of key importance. This authoritative two-volume collection provides a comprehensive review of the structure of an extensive range of textile fibres.Volume 2 begins by reviewing natural fibres such as cellulosic, cotton, protein, wool and silk fibres. Part two considers regenerated cellulosic, protein, alginate, chitin and chitosan fibres. The final part of the book discusses inorganic fibres such as glass, carbon and ceramic fibres as well as specialist fibres such as thermally and chemically-resistant fibres, optical and hollow fibres. Chapters review how fibre structure contributes to key mechanical properties. A companion volume reviews the structure of manufactured polymer fibres.Edited by leading authorities on the subject and with a team of international authors, the two volumes of the Handbook of textile fibre structure is an essential reference for textile technologists, fibre scientists, textile engineers and those in academia.

  • Neuromodulation

    • 1st Edition
    • Elliot S. Krames + 2 more
    • English
    Neuromodulation will be the first comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. This book provides a complete discussion of the fundamental principles of neuromodulation and therapies applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs.The textbook is highly structured and organized into overarching sections that cover chronic pain, movement disorders, psychiatric disorders, epilepsy, functional electrical stimulation, cardiac, gastrointestinal, genitourinary and organ neuromodulation. The fundamental principles of electricity and infusion, neural tissue interface, biomedical engineering, neuromodulation devices, basic science, neuroanatomy, neurophysiology, imaging and mechanisms are emphasized. In addition to providing details pertaining to the state-of-the-art current practice, innovative and emerging applications are discussed in specific chapters. Finally, the textbook provides specific chapters focusing on the technical aspects of the various neuromodulation procedures as well as technical specifications of various implantable devices.All of the contributors to Neuromodulation represent leading experts in the field. The editors are internationally renowned in their respective fields of neuromodulation, pain management, functional neurosurgery and biomedical engineering. Neuromodulation will be the first and foremost authoritative text on neuromodulation therapies and will establish the gold standard that defines the field for years to come.

  • Bioceramics and their Clinical Applications

    • 1st Edition
    • Tadashi Kokubo
    • English
    Bioceramics have been used very successfully within the human body for many years. They are commonly used in orthopaedic surgery and dentistry but they are potentially suitable for a wide range of important applications within the medical device industry. This important book reviews the range of bioceramics, their properties and range of clinical uses.Chapters in the first section of the book discusses issues of significance to a range of bioceramics such as their structure, mechanical properties and biological interactions. The second part reviews the fabrication, microstructure and properties of specific bioceramics and glasses, concentrating on the most promising materials. These include alumina and zirconia ceramics, bioactive glasses and bioactive glass-ceramics, calcium sulphate, tricalcium phosphate-based ceramics, hydroxyapatite, tricalcium phosphate/hydroxyapa... biphasic ceramics, si-substrated hydroxyapatite, calcium phosphate cement, calcium phosphate coating, titania-based materials, ceramic-polymer composites, dental ceramics and dental glass-ceramics. The final group of chapters reviews the clinical applications of bioceramics in joint replacement, bone grafts, tissue engineering and dentistry.Bioceramic... and their clinical applications is written by leading academics from around the world and it provides an authoritative review of this highly active area of research. This book is a useful resource for biomaterials scientists and engineers, as well as for clinicians and the academic community.

  • Tissue Engineering Using Ceramics and Polymers

    • 1st Edition
    • Aldo R. Boccaccini + 1 more
    • English
    Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering.

  • Biotechnology Annual Review

    • 1st Edition
    • Volume 11
    • M. Raafat El-Gewely
    • English
    Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists’ knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, vehicles for the production of biotechnology products and methods for their detection, separation and analysis - to topics that are focused on the role of biotechnology in the health sciences. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training.

  • Marine Bioprocess Engineering

    • 1st Edition
    • Volume 35
    • J.G. Burgess + 2 more
    • J. Tramper
    • English
    This book contains full papers of both oral and poster presentations of the international symposium 'Marine Bioprocess Engineering' which was held in Noordwijkerhout, The Netherlands, 1998. The symposium focused on the bioprocessing of marine natural products.Bioprocess engineering has been the key to success in the commercialization of biotechnology, especially with respect to biopharmaceuticals. In marine biotechnology, both new and existing biotechnological techniques are developed an applied to organisms from marine sources. For marine biotechnology, bioprocess engineering represents the link between discovery and commercialization.Th... diversity of marine life points to a myriad of new bioproducts waiting to be discovered and developed commercially.The volume begins to bridge the gap between the isolation of products from marine organisms in the laboratory and industrial applications by focusing on the bioprocess-engineeri... aspects. Reviews and recent developments in product discovery, bio-energy production, cultivation of marine organisms, scale up and product recovery are presented.This publication should ensure that the engineering aspects of marine biotechnology will receive further attention in the future. Exploration of new bioproducts from the ocean should be followed up by a sustainable exploitation of these valuable resources.

  • Animal Cell Culture Methods

    • 1st Edition
    • Volume 57
    • English
    This volume provides complete and thorough coverage of the classical and state-of-the-art methods used in cell culture. It also includes basic principles used in the selection of cells for specific scientific study, as well as analytical and procedural techniques.