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Books in Applied immunology

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11-20 of 46 results in All results

System Vaccinology

  • 1st Edition
  • August 20, 2022
  • Vijay Kumar Prajapati
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 8 5 9 4 1 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 8 9 7 8 6 - 0
Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials. My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines. This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens. Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

Clinical Immunology

  • 1st Edition
  • August 16, 2022
  • Nima Rezaei
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 8 0 0 6 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 8 0 0 7 - 5
Clinical Immunology not only introduces the reader to the human immune system, it also covers immunology from clinical manifestation to therapeutic approaches in a wide range of conditions. Each chapter describes an introduction, the clinical manifestations, the immunopathogenesis, diagnosis, lab tests and therapeutic approaches. The book guides clinicians, researchers and students to a better understanding of the matters of immunologic-based diseases that can lead to better decision-making for patients.Because of the growing knowledge regarding the function of immune system in health and disease conditions, clinicians, researchers and students increasingly require an exclusive scientific reference to guide them on matters of immunologic-based diseases. Accordingly, despite the existence of numerous high quality references in basic and cellular/molecular immunology which deeply explain different immunologic mechanisms, there is still a knowledge gap in the field of clinical immunology.

Microbial Crosstalk with Immune System

  • 1st Edition
  • July 26, 2022
  • Asmita Das
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 6 1 2 8 - 8
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 9 5 7 9 - 5
Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters. Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.

Macrophages in the Human Body

  • 1st Edition
  • June 8, 2022
  • Niels Olson Saraiva Camara + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 1 3 8 5 - 8
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 1 3 8 6 - 5
Through recent research, there has been a significant number of findings involving the biology of macrophages. Beyond the 1st line of defense, macrophages have several specific characteristics across different tissues, organs, and systems. Macrophages comprehend a heterogeneous phagocytic population with wide range phenotypes, and tissue-specific functions, such as bone resorption, extracellular matrix production, red blood cells and bacteria removal, among others. Through innate immune receptors macrophages can modulate several pathways that culminate in the production of various types of inflammatory mediators such as chemokines, cytokines, oxygen reactive species, and lipid mediators which ultimately altered the behavior of other cells. Moreover, environment signals modify and induce metabolic reprograming that it alters phenotype and functions.Macrophages in the Human Body: A Tissue Level Approach presents a current overview of the diversity of macrophages across multiple human body systems, their phenotype, function and metabolic characteristics. It covers translational aspects where there is research support to indicate the therapeutic potential.

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

  • 1st Edition
  • May 21, 2022
  • Keerti Jain + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 2 0 1 - 3
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 6 9 - 7
Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials. Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases.

Immunoinformatics of Cancers

  • 1st Edition
  • April 19, 2022
  • Nima Rezaei + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 2 4 0 0 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 2 4 3 0 - 4
Immunoinformatics of Cancers: Practical Machine Learning Approaches Using R takes a bioinformatics approach to understanding and researching the immunological aspects of malignancies. It details biological and computational principles and the current applications of bioinformatic approaches in the study of human malignancies. Three sections cover the role of immunology in cancers and bioinformatics, including databases and tools, R programming and useful packages, and present the foundations of machine learning. The book then gives practical examples to illuminate the application of immunoinformatics to cancer, along with practical details on how computational and biological approaches can best be integrated.This book provides readers with practical computational knowledge and techniques, including programming, and machine learning, enabling them to understand and pursue the immunological aspects of malignancies.

Vaccinology and Methods in Vaccine Research

  • 1st Edition
  • March 10, 2022
  • Rebecca Ashfield + 3 more
  • English
  • Paperback
    9 7 8 - 0 - 3 2 3 - 9 1 1 4 6 - 7
  • eBook
    9 7 8 - 0 - 3 2 3 - 9 1 4 3 8 - 3
Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field. It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodological advice.

Cancer Immunology and Immunotherapy

  • 1st Edition
  • August 18, 2021
  • Mansoor M. Amiji + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 2 3 3 9 7 - 9
  • eBook
    9 7 8 - 0 - 1 2 - 8 2 3 6 3 7 - 6
Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy examines the challenges of delivering immuno-oncology therapies. Immuno-oncology (IO) is a growing field of medicine at the interface of immunology and cancer biology leading to development of novel therapeutic approaches, such as chimeric antigen receptor T-cell (CAR-T) and immune checkpoint blockade antibodies, that are clinically approved approaches for cancer therapy. Although currently approved IO approaches have shown tremendous promise for select types of cancers, broad application of IO strategies could even further improve the clinical success, especially for diseases such as pancreatic cancer, brain tumors where the success of IO so far has been limited. Nanotechnology-based targeted delivery strategies could improve the delivery efficiency of IO agents as well as provide additional avenues for novel therapeutic and vaccination strategies. Additionally, a number of locally-administered immunogenic scaffolds and therapeutic strategies, such as the use of STING agonist, could benefit from rationally designed biomaterials and delivery approaches. Delivery Technologies for Immuno-Oncology: Volume 1: Delivery Strategies and Engineering Technologies in Cancer Immunotherapy creates a comprehensive treaty that engages the scientific and medical community who are involved in the challenges of immunology, cancer biology, and therapeutics with possible solutions from the nanotechnology and drug delivery side.

Epigenetics of the Immune System

  • 1st Edition
  • Volume 16
  • June 4, 2020
  • Dieter Kabelitz + 1 more
  • English
  • Paperback
    9 7 8 - 0 - 1 2 - 8 1 7 9 6 4 - 2
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 7 9 6 5 - 9
Epigenetics of the Immune System focuses on different aspects of epigenetics and immunology, providing readers with the fundamental mechanisms relating to epigenetics and the immune system. This book provides in-depth information on immune cells as a toolbox in deciphering systematically regulated mechanisms using "omics" and computational biology approaches. In addition, the book presents the translational importance of epigenetics and the immune system in our understanding of pathophysiology in diseases and its therapeutic applications.

Stiehm's Immune Deficiencies

  • 2nd Edition
  • May 23, 2020
  • Kathleen E. Sullivan + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 8 1 6 7 6 8 - 7
  • eBook
    9 7 8 - 0 - 1 2 - 8 1 7 2 9 5 - 7
Stiehm’s Immune Deficiencies: Inborn Errors in Immunity, Second Edition, is ideal for physicians and other caregivers who specialize in immunology, allergies, infectious diseases and pulmonary medicine. It provides a validated source of information for care delivery to patients, covering approaches to diagnosis that use both new genetic information and emphasize screening strategies. Management has changed dramatically over the past five years, so approaches to infection and autoimmunity are emphasized in an effort to improve outcomes and disseminate new information on the uses of targeted therapy.

Related subjects

Immunotherapy

Vaccinology