Nanotheranostics for Treatment and Diagnosis of Infectious Diseases

1st Edition - May 21, 2022
Editors: Keerti Jain, Javed Ahmad
Language: English
Paperback ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 2 0 1 - 3
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 9 1 4 6 9 - 7

Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for appli… Read more

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Nanotheranostics for Treatment and Diagnosis of Infectious Diseases comprises the latest information on the technological advancements made in the field of nanotechnology for application in therapeutics with diagnostic applications. The book focuses on the theranostic applications of nanomaterials in infectious diseases, highlighting that rapid diagnosis, safe and effective treatment and strong preventive measures like vaccines are urgently needed. It compiles all relevant information to help scientists, researchers and students understand the role of nanomaterials, how nanomaterials could be explored simultaneously for therapeutic and diagnostic applications, and how to ensure safety and efficacy of these nanomaterials.

Sections cover fundamental concepts, emerging concerns and challenges to combat infectious diseases, the characterization of nanomaterials for theranostic applications, and the toxicity, biocompatibility and regulatory perspectives in the diagnosis and treatment of infectious diseases.

Cover image
Title page
Table of Contents
Copyright
Dedication
Contributors
Editor’s biographies
Preface
Chapter 1: Emerging concerns of infectious diseases and drug delivery challenges
Abstract
Acknowledgment
1: Introduction
2: Emerging concerns of infectious diseases
3: Drug delivery in infectious diseases
4: Challenges associated with treatment of infectious diseases
5: Drug delivery challenges in infectious diseases
6: Strategies to deal with challenge
7: Current scenario and future perspectives
8: Conclusions and summary
References
Chapter 2: Combating MDR in infectious diseases using nanomaterials
Abstract
Conflict of interest
1: Introduction
2: Mechanism of antimicrobial resistance
3: Strategies to combat drug resistance in infectious diseases
4: Nanomaterials as new weapons to combat MDR
5: Future prospective
6: Conclusion
References
Chapter 3: Engineering and functionalization of nanomaterials for theranostic applications in infectious diseases
Abstract
1: Introduction
2: Engineered nanomaterials for infectious diseases
3: Common methods of diagnosis of microbes using nanoparticles
4: Theranostic nanomaterial for simultaneous imaging and therapy of infected cells
5: Conclusion
References
Chapter 4: In vitro evaluation and spectroscopic characterization of nanomaterials for theranostic applications
Abstract
1: Introduction
2: Different techniques for characterization of nanomaterials
3: Characterization of solid-state properties
4: Evaluation of in vitro absorption profile
5: Conclusion
References
Chapter 5: In vivo evaluation and imaging of nanomaterials for theranostic applications
Abstract
1: Introduction
2: In vivo evaluation of nanoparticles
3: Nanoparticles in imaging
4: Conclusion
References
Chapter 6: Polymeric nanomaterials for infectious diseases
Abstract
1: Introduction
2: Malaria
3: Tuberculosis
4: HIV
5: Hepatitis B
6: Covid-19
7: Zika virus
8: Cholera
9: Influenza
10: Conclusion and future trends
References
Chapter 7: Stimuli-responsive nanomaterials in infectious diseases
Abstract
1: Introduction
2: Endogenous vs exogenous vs dual/multi-stimuli-responsive systems
3: Endogenous stimuli-responsive systems
4: Exogenous stimuli-responsive systems
5: Dual and multi-stimuli-responsive systems
6: Theranostic applications of stimuli-responsive nanomaterials
7: Concluding remarks and future perspectives
References
Chapter 8: Dendrimers and its theranostic applications in infectious diseases
Abstract
1: Introduction
2: Dendrimers as theranostic nanomaterials
3: Dendrimers with other nanomaterials for theranostic applications
4: Theranostic applications of dendrimer in infectious diseases
5: Current scenario and future perspectives
6: Conclusion and future perspectives
References
Chapter 9: Lipid nanoparticles and nanoemulsions exploited in the diagnosis and treatment of infectious diseases
Abstract
1: Introduction
2: Infectious diseases overview
3: Lipid based nanoparticles: Evolution and applications
4: Development methods of iLNPs
5: Application of lipid-based nanoparticles in infectious diseases
6: Nanoemulsions: Evolution and applications
7: Development methods of nanoemulsions
8: Applications of nanoemulsions in infectious diseases
9: Theranostic applications of lipid-based nanoparticles and nanoemulsion in infectious diseases: Author opinion and contemporary research
10: Future perspective of lipid nanocarriers in infectious diseases
References
Chapter 10: Liposomes and their theranostic applications in infectious diseases
Abstract
1: Introduction
2: Liposomes for infectious disease
3: Composition of theranostic liposomes
4: Theranostic liposomes
5: Theranostic liposomes for infectious disease
6: Application of theranostic liposomes
7: Conclusion
References
Chapter 11: Metallic nanomaterials for the diagnosis and treatment of infectious diseases
Abstract
1: Introduction
2: Fabrication of metallic nanoparticles
3: Metallic nanomaterials for the diagnosis and treatment
4: Summary
References
Chapter 12: Tuning the properties of inorganic nanomaterials for theranostic applications in infectious diseases: Carbon nanotubes, quantum dots, graphene, and mesoporous carbon nanoparticles
Abstract
Acknowledgments
1: Introduction
2: Carbon-based inorganic nanomaterials
3: Properties of carbon nanomaterials
4: Theranostics applications of carbon nanomaterials in infectious disease
5: Conclusions and future perspectives
References
Chapter 13: Toxicity and biocompatibility perspective of nanomaterials exploited in diagnosis and treatment of infectious diseases
Abstract
1: Introduction
2: Nanomaterials used in infectious disease
3: Polymeric nanomaterials
4: Factor affecting safety aspects of nanomaterials
5: Safety assessment of nanomaterials in infections disease
6: Conclusion
References
Chapter 14: Regulatory perspectives of nanomaterials for theranostic application
Abstract
1: Introduction
2: Need of nanomaterials regulation
3: Challenges to market authorization of nanomaterials
4: Nanomaterials under clinical trial for theranostic application
5: Global regulatory perspectives of nanomaterials (NMs)
6: Concluding remarks
References
Index

Keerti Jain

Dr Keerti Jain earned her MPharm and doctorate degree from the Department of Pharmaceutical Sciences, Dr HS Gour Central University, Sagar, India. She received her post-doctorate degree from Maharaja Sayajirao University of Baroda, Vadodara, India, as SERB-National Post-doctoral Fellow. She has more than 10 years of research experience in nanomedicine-based drug delivery systems. Currently, she is proficiently fulfilling her responsibilities as Assistant Professor and Scientist at the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, Lucknow, India. Dr Jain has supervised MPharm. and PharmD students in their research, which has been published in quality journals with a high impact factor. She is the author of more than 60 documents in international, peer-reviewed, high-impact journals, including publications in Progress in Polymer Science, having an impact factor of 22.620, Biomaterials, Drug Discovery Today, Nanomedicine, Current Opinion in Pharmacology, Antimicrobial Agents and Chemotherapy, and others with high-impact factors. Her review articles entitled Dendrimer Toxicity: Let’s Meet the Challenge and Dendrimers as Nanocarriers in Drug Delivery, published in the International Journal of Pharmaceutics and Progress in Polymer Science, were listed in the top 25 articles. She has published 1 book and 15 book chapters with international publishers. She has been awarded research fellowships including, SERB – Post-doctorate Fellowship, Senior Research Fellowship (CSIR), Junior Research Fellowship (UGC), Fellowship for Training Young Scientists (MPCST), Travel Grant Award (INSA), and International Travel Fellowship (ICMR and DBT), as well as several other prestigious grants, fellowships, and awards.

Affiliations and expertise

Assistant Professor, National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, Lucknow, India; Scientist, National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, Lucknow, India

Javed Ahmad

Dr Javed Ahmad is presently working as an Assistant Professor in Department of Pharmaceutics, College of Pharmacy, Najran University, Najran, Saudi Arabia. He has research experience of about 10 years in the field of nanomedicine-mediated drug delivery. He obtained his PhD in pharmaceutics from Jamia Hamdard, New Delhi, India. He was awarded with senior research fellowships from the Council of Scientific and Industrial Research (CSIR), Government of India. He was also awarded with international travel grants from the Department of Science and Technology (DST), Government of India. He has more than 50 publications to his credit, in various journals of international repute. He has authored 15 book chapters and edited 2 books for CRC Press and Bentham Science Publisher. Currently, he is involved in drug delivery through nanocarriers, exploiting various routes of administration and 3D printing of pharmaceuticals.

Affiliations and expertise

Assistant Professor, Department of Pharmaceutics, College of Pharmacy, Najran University, Najran, Saudi Arabia

Life Sciences

Physical Sciences & Engineering

Social Sciences & Humanities

Health